PubMed:6809737
Annnotations
Test-Species-PubTator
| Id | Subject | Object | Predicate | Lexical cue | resolved_to |
|---|---|---|---|---|---|
| 4 | 13-40 | Chemical | denotes | 6-oxoprostaglandin F1 alpha | MESH:D015121 |
| 5 | 42-74 | Chemical | denotes | 6,15-dioxoprostaglandin F1 alpha | - |
| 6 | 80-112 | Chemical | denotes | monohydroxyicosatetraenoic acids | - |
| 7 | 118-134 | Chemical | denotes | arachidonic acid | MESH:D016718 |
| 33 | 241-257 | Chemical | denotes | arachidonic acid | MESH:D016718 |
| 34 | 330-370 | Chemical | denotes | 12-hydroxy-5,8,10-heptadecatrienoic acid | MESH:C008033 |
| 35 | 372-413 | Chemical | denotes | 11-hydroxy-5,8,12,14-icosatetraenoic acid | - |
| 36 | 415-423 | Chemical | denotes | 11h-20:4 | - |
| 37 | 430-471 | Chemical | denotes | 15-hydroxy-5,8,11,13-icosatetraenoic acid | - |
| 38 | 516-557 | Chemical | denotes | 12-hydroxy-5,8,10,14-icosatetraenoic acid | - |
| 39 | 559-567 | Chemical | denotes | 12h-20:4 | - |
| 40 | 755-763 | Chemical | denotes | 11h-20:4 | - |
| 41 | 909-921 | Chemical | denotes | indomethacin | MESH:D007213 |
| 42 | 933-958 | Chemical | denotes | nordihydroguaiaretic acid | MESH:D009637 |
| 43 | 977-985 | Chemical | denotes | 12h-20:4 | - |
| 44 | 1024-1036 | Chemical | denotes | indomethacin | MESH:D007213 |
| 45 | 1105-1133 | Chemical | denotes | hydroxyicosatetraenoic acids | - |
| 46 | 1161-1171 | Chemical | denotes | adrenaline | MESH:D004837 |
| 47 | 1234-1250 | Chemical | denotes | arachidonic acid | MESH:D016718 |
| 48 | 1458-1468 | Chemical | denotes | adrenaline | MESH:D004837 |
| 49 | 1470-1481 | Chemical | denotes | glutathione | MESH:D005978 |
| 50 | 1487-1497 | Chemical | denotes | tryptophan | MESH:D014364 |
| 51 | 1572-1588 | Chemical | denotes | arachidonic acid | MESH:D016718 |
| 52 | 1592-1610 | Chemical | denotes | 15-hydroperoxyPGI2 | - |
| 53 | 1685-1689 | Chemical | denotes | PGI2 | MESH:D011464 |
| 54 | 1712-1722 | Chemical | denotes | 15-oxoPGI2 | - |
| 55 | 1741-1755 | Chemical | denotes | hydroperoxides | MESH:D006861 |
| 56 | 1761-1777 | Chemical | denotes | arachidonic acid | MESH:D016718 |
| 57 | 1821-1825 | Chemical | denotes | PGI2 | MESH:D011464 |
Test-Species-PubDictionaries-PubMedBERT
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 574-578 | Species | denotes | also | 209674 |
| T2 | 684-690 | Species | denotes | normal | 2974449 |
GlyCosmos6-Glycan-Motif-Image
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 32-40 | Glycan_Motif | denotes | F1 alpha | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G61730RY|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G21312EA |
| T3 | 66-74 | Glycan_Motif | denotes | F1 alpha | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G61730RY|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G21312EA |
| T5 | 280-288 | Glycan_Motif | denotes | F1 alpha | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G61730RY|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G21312EA |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-177 | Sentence | denotes | Formation of 6-oxoprostaglandin F1 alpha, 6,15-dioxoprostaglandin F1 alpha, and monohydroxyicosatetraenoic acids from arachidonic acid by fetal calf aorta and ductus arteriosus. |
| T2 | 178-483 | Sentence | denotes | Particulate fractions and slices from fetal calf aorta convert arachidonic acid to 6-oxoprostaglandin F1 alpha (6-oxoPGF1 alpha), 6,15-dioxoPGF1 alpha, 12-hydroxy-5,8,10-heptadecatrienoic acid, 11-hydroxy-5,8,12,14-icosatetraenoic acid (11h-20:4), and 15-hydroxy-5,8,11,13-icosatetraenoic acid (15h-20:4). |
| T3 | 484-588 | Sentence | denotes | In some cases, small amounts of 12-hydroxy-5,8,10,14-icosatetraenoic acid (12h-20:4) were also detected. |
| T4 | 589-749 | Sentence | denotes | The products were all identified by gas chromatography-mass spectrometry after purification by normal phase and argentation high pressure liquid chromatography. |
| T5 | 750-959 | Sentence | denotes | Both 11h-20:4 and 15h-20:4 appeared to be formed by prostaglandin endoperoxide synthetase rather than by lipoxygenases, since their formation was inhibited by indomethacin but not by nordihydroguaiaretic acid. |
| T6 | 960-1087 | Sentence | denotes | The formation of 12h-20:4, on the other hand, was stimulated by indomethacin, probably due to increased substrate availability. |
| T7 | 1088-1172 | Sentence | denotes | The formation of hydroxyicosatetraenoic acids was markedly stimulated by adrenaline. |
| T8 | 1173-1378 | Sentence | denotes | Substantial amounts of 6,15-dioxoPGF1 alpha were formed from arachidonic acid by particulate fractions from fetal calf blood vessels, especially in the presence of relatively high substrate concentrations. |
| T9 | 1379-1498 | Sentence | denotes | The formation of this product was stimulated by methemoglobin and inhibited by adrenaline, glutathione, and tryptophan. |
| T10 | 1499-1723 | Sentence | denotes | It would appear that particulate fractions from fetal calf aorta convert arachidonic acid to 15-hydroperoxyPGI2, which can either be reduced in the presence of various cofactors to form PGI2 or dehydrated to give 15-oxoPGI2. |
| T11 | 1724-1912 | Sentence | denotes | The formation of hydroperoxides from arachidonic acid could be an important factor in regulating PGI2 synthesis in aorta, since PGI2 synthetase is strongly inhibited by such intermediates. |
| T1 | 0-177 | Sentence | denotes | Formation of 6-oxoprostaglandin F1 alpha, 6,15-dioxoprostaglandin F1 alpha, and monohydroxyicosatetraenoic acids from arachidonic acid by fetal calf aorta and ductus arteriosus. |
| T2 | 178-483 | Sentence | denotes | Particulate fractions and slices from fetal calf aorta convert arachidonic acid to 6-oxoprostaglandin F1 alpha (6-oxoPGF1 alpha), 6,15-dioxoPGF1 alpha, 12-hydroxy-5,8,10-heptadecatrienoic acid, 11-hydroxy-5,8,12,14-icosatetraenoic acid (11h-20:4), and 15-hydroxy-5,8,11,13-icosatetraenoic acid (15h-20:4). |
| T3 | 484-588 | Sentence | denotes | In some cases, small amounts of 12-hydroxy-5,8,10,14-icosatetraenoic acid (12h-20:4) were also detected. |
| T4 | 589-749 | Sentence | denotes | The products were all identified by gas chromatography-mass spectrometry after purification by normal phase and argentation high pressure liquid chromatography. |
| T5 | 750-959 | Sentence | denotes | Both 11h-20:4 and 15h-20:4 appeared to be formed by prostaglandin endoperoxide synthetase rather than by lipoxygenases, since their formation was inhibited by indomethacin but not by nordihydroguaiaretic acid. |
| T6 | 960-1087 | Sentence | denotes | The formation of 12h-20:4, on the other hand, was stimulated by indomethacin, probably due to increased substrate availability. |
| T7 | 1088-1172 | Sentence | denotes | The formation of hydroxyicosatetraenoic acids was markedly stimulated by adrenaline. |
| T8 | 1173-1378 | Sentence | denotes | Substantial amounts of 6,15-dioxoPGF1 alpha were formed from arachidonic acid by particulate fractions from fetal calf blood vessels, especially in the presence of relatively high substrate concentrations. |
| T9 | 1379-1498 | Sentence | denotes | The formation of this product was stimulated by methemoglobin and inhibited by adrenaline, glutathione, and tryptophan. |
| T10 | 1499-1723 | Sentence | denotes | It would appear that particulate fractions from fetal calf aorta convert arachidonic acid to 15-hydroperoxyPGI2, which can either be reduced in the presence of various cofactors to form PGI2 or dehydrated to give 15-oxoPGI2. |
| T11 | 1724-1912 | Sentence | denotes | The formation of hydroperoxides from arachidonic acid could be an important factor in regulating PGI2 synthesis in aorta, since PGI2 synthetase is strongly inhibited by such intermediates. |
GlyCosmos6-Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 32-40 | https://glytoucan.org/Structures/Glycans/G21312EA | denotes | F1 alpha |
| T2 | 32-40 | https://glytoucan.org/Structures/Glycans/G61730RY | denotes | F1 alpha |
| T3 | 66-74 | https://glytoucan.org/Structures/Glycans/G21312EA | denotes | F1 alpha |
| T4 | 66-74 | https://glytoucan.org/Structures/Glycans/G61730RY | denotes | F1 alpha |
| T5 | 280-288 | https://glytoucan.org/Structures/Glycans/G21312EA | denotes | F1 alpha |
| T6 | 280-288 | https://glytoucan.org/Structures/Glycans/G61730RY | denotes | F1 alpha |
Glycosmos6-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 32-40 | http://www.glycoepitope.jp/epitopes/EP0024 | denotes | F1 alpha |
| T2 | 66-74 | http://www.glycoepitope.jp/epitopes/EP0024 | denotes | F1 alpha |
| T3 | 280-288 | http://www.glycoepitope.jp/epitopes/EP0024 | denotes | F1 alpha |
Glycosmos6-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 149-154 | http://purl.obolibrary.org/obo/MAT_0000035 | denotes | aorta |
| T2 | 227-232 | http://purl.obolibrary.org/obo/MAT_0000035 | denotes | aorta |
| T3 | 1000-1004 | http://purl.obolibrary.org/obo/MAT_0000091 | denotes | hand |
| T4 | 1292-1305 | http://purl.obolibrary.org/obo/MAT_0000393 | denotes | blood vessels |
| T5 | 1292-1297 | http://purl.obolibrary.org/obo/MAT_0000083 | denotes | blood |
| T6 | 1292-1297 | http://purl.obolibrary.org/obo/MAT_0000315 | denotes | blood |
| T7 | 1558-1563 | http://purl.obolibrary.org/obo/MAT_0000035 | denotes | aorta |
| T8 | 1839-1844 | http://purl.obolibrary.org/obo/MAT_0000035 | denotes | aorta |
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 32-40 | Glycan | denotes | F1 alpha | https://api.glycosmos.org/wurcs2image/latest/png/binary/G61730RY |
| T2 | 66-74 | Glycan | denotes | F1 alpha | https://api.glycosmos.org/wurcs2image/latest/png/binary/G61730RY |
| T3 | 280-288 | Glycan | denotes | F1 alpha | https://api.glycosmos.org/wurcs2image/latest/png/binary/G61730RY |
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 149-154 | Body_part | denotes | aorta | http://purl.obolibrary.org/obo/MAT_0000035 |
| T2 | 227-232 | Body_part | denotes | aorta | http://purl.obolibrary.org/obo/MAT_0000035 |
| T3 | 1000-1004 | Body_part | denotes | hand | http://purl.obolibrary.org/obo/MAT_0000091 |
| T4 | 1292-1305 | Body_part | denotes | blood vessels | http://purl.obolibrary.org/obo/MAT_0000393 |
| T5 | 1558-1563 | Body_part | denotes | aorta | http://purl.obolibrary.org/obo/MAT_0000035 |
| T6 | 1839-1844 | Body_part | denotes | aorta | http://purl.obolibrary.org/obo/MAT_0000035 |
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 32-40 | Glycan | denotes | F1 alpha | https://api.glycosmos.org/wurcs2image/latest/png/binary/G61730RY |
| T2 | 66-74 | Glycan | denotes | F1 alpha | https://api.glycosmos.org/wurcs2image/latest/png/binary/G61730RY |
| T3 | 280-288 | Glycan | denotes | F1 alpha | https://api.glycosmos.org/wurcs2image/latest/png/binary/G61730RY |
GlyCosmos-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 32-40 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | F1 alpha | http://www.glycoepitope.jp/epitopes/EP0024 |
| T2 | 66-74 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | F1 alpha | http://www.glycoepitope.jp/epitopes/EP0024 |
| T3 | 280-288 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | F1 alpha | http://www.glycoepitope.jp/epitopes/EP0024 |
GlyCosmos15-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 159-176 | Phenotype | denotes | ductus arteriosus | HP:0001643 |
GlyCosmos15-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 149-154 | Body_part | denotes | aorta | http://purl.obolibrary.org/obo/UBERON_0000947 |
| T2 | 159-176 | Body_part | denotes | ductus arteriosus | http://purl.obolibrary.org/obo/UBERON_0005440 |
| T3 | 227-232 | Body_part | denotes | aorta | http://purl.obolibrary.org/obo/UBERON_0000947 |
| T4 | 1000-1004 | Body_part | denotes | hand | http://purl.obolibrary.org/obo/UBERON_0002398 |
| T5 | 1292-1305 | Body_part | denotes | blood vessels | http://purl.obolibrary.org/obo/UBERON_0004537 |
| T6 | 1558-1563 | Body_part | denotes | aorta | http://purl.obolibrary.org/obo/UBERON_0000947 |
| T7 | 1839-1844 | Body_part | denotes | aorta | http://purl.obolibrary.org/obo/UBERON_0000947 |
GlyCosmos15-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 32-40 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | F1 alpha | http://www.glycoepitope.jp/epitopes/EP0024 |
| T2 | 66-74 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | F1 alpha | http://www.glycoepitope.jp/epitopes/EP0024 |
| T3 | 280-288 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | F1 alpha | http://www.glycoepitope.jp/epitopes/EP0024 |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-177 | Sentence | denotes | Formation of 6-oxoprostaglandin F1 alpha, 6,15-dioxoprostaglandin F1 alpha, and monohydroxyicosatetraenoic acids from arachidonic acid by fetal calf aorta and ductus arteriosus. |
| T2 | 178-483 | Sentence | denotes | Particulate fractions and slices from fetal calf aorta convert arachidonic acid to 6-oxoprostaglandin F1 alpha (6-oxoPGF1 alpha), 6,15-dioxoPGF1 alpha, 12-hydroxy-5,8,10-heptadecatrienoic acid, 11-hydroxy-5,8,12,14-icosatetraenoic acid (11h-20:4), and 15-hydroxy-5,8,11,13-icosatetraenoic acid (15h-20:4). |
| T3 | 484-588 | Sentence | denotes | In some cases, small amounts of 12-hydroxy-5,8,10,14-icosatetraenoic acid (12h-20:4) were also detected. |
| T4 | 589-749 | Sentence | denotes | The products were all identified by gas chromatography-mass spectrometry after purification by normal phase and argentation high pressure liquid chromatography. |
| T5 | 750-959 | Sentence | denotes | Both 11h-20:4 and 15h-20:4 appeared to be formed by prostaglandin endoperoxide synthetase rather than by lipoxygenases, since their formation was inhibited by indomethacin but not by nordihydroguaiaretic acid. |
| T6 | 960-1087 | Sentence | denotes | The formation of 12h-20:4, on the other hand, was stimulated by indomethacin, probably due to increased substrate availability. |
| T7 | 1088-1172 | Sentence | denotes | The formation of hydroxyicosatetraenoic acids was markedly stimulated by adrenaline. |
| T8 | 1173-1378 | Sentence | denotes | Substantial amounts of 6,15-dioxoPGF1 alpha were formed from arachidonic acid by particulate fractions from fetal calf blood vessels, especially in the presence of relatively high substrate concentrations. |
| T9 | 1379-1498 | Sentence | denotes | The formation of this product was stimulated by methemoglobin and inhibited by adrenaline, glutathione, and tryptophan. |
| T10 | 1499-1723 | Sentence | denotes | It would appear that particulate fractions from fetal calf aorta convert arachidonic acid to 15-hydroperoxyPGI2, which can either be reduced in the presence of various cofactors to form PGI2 or dehydrated to give 15-oxoPGI2. |
| T11 | 1724-1912 | Sentence | denotes | The formation of hydroperoxides from arachidonic acid could be an important factor in regulating PGI2 synthesis in aorta, since PGI2 synthetase is strongly inhibited by such intermediates. |
GlyCosmos15-FMA
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 144-148 | Body_part | denotes | calf | FMA:24984 |
| T2 | 149-154 | Body_part | denotes | aorta | FMA:3734 |
| T3 | 159-176 | Body_part | denotes | ductus arteriosus | FMA:79871 |
| T4 | 222-226 | Body_part | denotes | calf | FMA:24984 |
| T5 | 227-232 | Body_part | denotes | aorta | FMA:3734 |
| T6 | 1000-1004 | Body_part | denotes | hand | FMA:9712 |
| T7 | 1287-1291 | Body_part | denotes | calf | FMA:24984 |
| T8 | 1292-1305 | Body_part | denotes | blood vessels | FMA:63183 |
| T9 | 1553-1557 | Body_part | denotes | calf | FMA:24984 |
| T10 | 1558-1563 | Body_part | denotes | aorta | FMA:3734 |
| T11 | 1839-1844 | Body_part | denotes | aorta | FMA:3734 |
GlyCosmos15-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 149-154 | Body_part | denotes | aorta | http://purl.obolibrary.org/obo/MAT_0000035 |
| T2 | 227-232 | Body_part | denotes | aorta | http://purl.obolibrary.org/obo/MAT_0000035 |
| T3 | 1000-1004 | Body_part | denotes | hand | http://purl.obolibrary.org/obo/MAT_0000091 |
| T4 | 1292-1305 | Body_part | denotes | blood vessels | http://purl.obolibrary.org/obo/MAT_0000393 |
| T5 | 1558-1563 | Body_part | denotes | aorta | http://purl.obolibrary.org/obo/MAT_0000035 |
| T6 | 1839-1844 | Body_part | denotes | aorta | http://purl.obolibrary.org/obo/MAT_0000035 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 149-154 | Body_part | denotes | aorta | http://purl.obolibrary.org/obo/UBERON_0000947 |
| T2 | 159-176 | Body_part | denotes | ductus arteriosus | http://purl.obolibrary.org/obo/UBERON_0005440 |
| T3 | 227-232 | Body_part | denotes | aorta | http://purl.obolibrary.org/obo/UBERON_0000947 |
| T4 | 1000-1004 | Body_part | denotes | hand | http://purl.obolibrary.org/obo/UBERON_0002398 |
| T5 | 1292-1305 | Body_part | denotes | blood vessels | http://purl.obolibrary.org/obo/UBERON_0004537 |
| T6 | 1558-1563 | Body_part | denotes | aorta | http://purl.obolibrary.org/obo/UBERON_0000947 |
| T7 | 1839-1844 | Body_part | denotes | aorta | http://purl.obolibrary.org/obo/UBERON_0000947 |
HP-phenotype
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 159-176 | Phenotype | denotes | ductus arteriosus | HP:0001643 |