PubMed:6773658 JSONTXT

{"project":"Test-Species-PubTator","denotations":[{"id":"2","span":{"begin":33,"end":41},"obj":"Chemical"},{"id":"3","span":{"begin":124,"end":144},"obj":"Species"},{"id":"23","span":{"begin":146,"end":211},"obj":"Chemical"},{"id":"24","span":{"begin":227,"end":235},"obj":"Chemical"},{"id":"25","span":{"begin":256,"end":272},"obj":"Chemical"},{"id":"26","span":{"begin":327,"end":347},"obj":"Species"},{"id":"27","span":{"begin":366,"end":383},"obj":"Species"},{"id":"28","span":{"begin":414,"end":419},"obj":"Chemical"},{"id":"29","span":{"begin":450,"end":459},"obj":"Chemical"},{"id":"30","span":{"begin":462,"end":470},"obj":"Chemical"},{"id":"31","span":{"begin":473,"end":479},"obj":"Chemical"},{"id":"32","span":{"begin":482,"end":487},"obj":"Chemical"},{"id":"33","span":{"begin":515,"end":523},"obj":"Chemical"},{"id":"34","span":{"begin":544,"end":557},"obj":"Chemical"},{"id":"35","span":{"begin":559,"end":607},"obj":"Chemical"},{"id":"36","span":{"begin":653,"end":669},"obj":"Chemical"},{"id":"37","span":{"begin":671,"end":697},"obj":"Chemical"},{"id":"38","span":{"begin":880,"end":896},"obj":"Chemical"},{"id":"39","span":{"begin":935,"end":950},"obj":"Chemical"},{"id":"40","span":{"begin":1010,"end":1026},"obj":"Chemical"},{"id":"41","span":{"begin":1086,"end":1092},"obj":"Chemical"}],"attributes":[{"id":"A2","pred":"resolved_to","subj":"2","obj":"MESH:D048271"},{"id":"A3","pred":"resolved_to","subj":"3","obj":"1911"},{"id":"A23","pred":"resolved_to","subj":"23","obj":"-"},{"id":"A24","pred":"resolved_to","subj":"24","obj":"MESH:D048271"},{"id":"A25","pred":"resolved_to","subj":"25","obj":"MESH:C012693"},{"id":"A26","pred":"resolved_to","subj":"26","obj":"1911"},{"id":"A28","pred":"resolved_to","subj":"28","obj":"-"},{"id":"A29","pred":"resolved_to","subj":"29","obj":"-"},{"id":"A30","pred":"resolved_to","subj":"30","obj":"-"},{"id":"A31","pred":"resolved_to","subj":"31","obj":"-"},{"id":"A32","pred":"resolved_to","subj":"32","obj":"-"},{"id":"A33","pred":"resolved_to","subj":"33","obj":"MESH:D048271"},{"id":"A34","pred":"resolved_to","subj":"34","obj":"-"},{"id":"A35","pred":"resolved_to","subj":"35","obj":"-"},{"id":"A36","pred":"resolved_to","subj":"36","obj":"-"},{"id":"A37","pred":"resolved_to","subj":"37","obj":"-"},{"id":"A38","pred":"resolved_to","subj":"38","obj":"MESH:C012693"},{"id":"A39","pred":"resolved_to","subj":"39","obj":"-"},{"id":"A40","pred":"resolved_to","subj":"40","obj":"MESH:C012693"},{"id":"A41","pred":"resolved_to","subj":"41","obj":"MESH:D002686"}],"text":"The effects of N-substitution of chitosan and the physical form of the products on the rate of hydrolysis by chitinase from Streptomyces griseus.\nN-Formyl, N-chloroacetyl, N-glycyl, N-isobutyryl, and N-pentanoyl derivatives of chitosan have been prepared. N-Acetylchitosan was the derivative most susceptible to chitinase from Streptomyces griseus and lysozyme from chicken egg-white, but with respect to R in the RCOHN group were CH3 \u003e CH3CH2 \u003e H \u003e CH3CH2CH2 \u003e (CH3)2CH \u003e NH2CH2 \u003e CICH2. Neither enzyme hydrolysed chitosan or its N-methylene. N-benzylidene, N-benzoyl, N-nicotinyl, and N-fatty acyl (C5-C18) derivatives, and lysozyme did not hydrolyse N-butyrychitosan. N-Acetylhexanoyl-chitosans, which had d.s. ratios of approximately 0.7: approximately 0.3 and approximately 0.3: approximately 0.7, were hydrolysed at approximately 0.75 and approximately 0.004 of the rate of N-acetylchitosan (powder) by chitinase. O-Acylation of N-acylchitosans caused a decrease in the rates of hydrolysis by chitinase. N-Acetylchitosan gels were hydrolysed at 8-13 times the rate for crab-shell chitin. These results indicate that not only N- and O-substituents but also the physical form of the substrates influence the rates of hydrolysis by these enzymes."}

{"project":"Test-Species-PubDictionaries","denotations":[{"id":"T1","span":{"begin":124,"end":144},"obj":"OrganismTaxon"},{"id":"T2","span":{"begin":327,"end":347},"obj":"OrganismTaxon"}],"attributes":[{"id":"A1","pred":"db_id","subj":"T1","obj":"1911"},{"id":"A2","pred":"db_id","subj":"T2","obj":"1911"}],"text":"The effects of N-substitution of chitosan and the physical form of the products on the rate of hydrolysis by chitinase from Streptomyces griseus.\nN-Formyl, N-chloroacetyl, N-glycyl, N-isobutyryl, and N-pentanoyl derivatives of chitosan have been prepared. N-Acetylchitosan was the derivative most susceptible to chitinase from Streptomyces griseus and lysozyme from chicken egg-white, but with respect to R in the RCOHN group were CH3 \u003e CH3CH2 \u003e H \u003e CH3CH2CH2 \u003e (CH3)2CH \u003e NH2CH2 \u003e CICH2. Neither enzyme hydrolysed chitosan or its N-methylene. N-benzylidene, N-benzoyl, N-nicotinyl, and N-fatty acyl (C5-C18) derivatives, and lysozyme did not hydrolyse N-butyrychitosan. N-Acetylhexanoyl-chitosans, which had d.s. ratios of approximately 0.7: approximately 0.3 and approximately 0.3: approximately 0.7, were hydrolysed at approximately 0.75 and approximately 0.004 of the rate of N-acetylchitosan (powder) by chitinase. O-Acylation of N-acylchitosans caused a decrease in the rates of hydrolysis by chitinase. N-Acetylchitosan gels were hydrolysed at 8-13 times the rate for crab-shell chitin. These results indicate that not only N- and O-substituents but also the physical form of the substrates influence the rates of hydrolysis by these enzymes."}

{"project":"Test-Species-PubDictionaries-PubMedBERT","denotations":[{"id":"T1","span":{"begin":109,"end":144},"obj":"Species"},{"id":"T2","span":{"begin":312,"end":347},"obj":"Species"},{"id":"T3","span":{"begin":366,"end":373},"obj":"Species"},{"id":"T4","span":{"begin":378,"end":383},"obj":"Species"},{"id":"T5","span":{"begin":420,"end":425},"obj":"Species"},{"id":"T6","span":{"begin":1075,"end":1079},"obj":"Species"},{"id":"T7","span":{"begin":1157,"end":1161},"obj":"Species"}],"attributes":[{"id":"A1","pred":"db_id","subj":"T1","obj":"2752516"},{"id":"A2","pred":"db_id","subj":"T2","obj":"2752516"},{"id":"A3","pred":"db_id","subj":"T3","obj":"9031"},{"id":"A4","pred":"db_id","subj":"T4","obj":"64459"},{"id":"A5","pred":"db_id","subj":"T5","obj":"536441"},{"id":"A6","pred":"db_id","subj":"T6","obj":"4270"},{"id":"A7","pred":"db_id","subj":"T7","obj":"209674"}],"text":"The effects of N-substitution of chitosan and the physical form of the products on the rate of hydrolysis by chitinase from Streptomyces griseus.\nN-Formyl, N-chloroacetyl, N-glycyl, N-isobutyryl, and N-pentanoyl derivatives of chitosan have been prepared. N-Acetylchitosan was the derivative most susceptible to chitinase from Streptomyces griseus and lysozyme from chicken egg-white, but with respect to R in the RCOHN group were CH3 \u003e CH3CH2 \u003e H \u003e CH3CH2CH2 \u003e (CH3)2CH \u003e NH2CH2 \u003e CICH2. Neither enzyme hydrolysed chitosan or its N-methylene. N-benzylidene, N-benzoyl, N-nicotinyl, and N-fatty acyl (C5-C18) derivatives, and lysozyme did not hydrolyse N-butyrychitosan. N-Acetylhexanoyl-chitosans, which had d.s. ratios of approximately 0.7: approximately 0.3 and approximately 0.3: approximately 0.7, were hydrolysed at approximately 0.75 and approximately 0.004 of the rate of N-acetylchitosan (powder) by chitinase. O-Acylation of N-acylchitosans caused a decrease in the rates of hydrolysis by chitinase. N-Acetylchitosan gels were hydrolysed at 8-13 times the rate for crab-shell chitin. These results indicate that not only N- and O-substituents but also the physical form of the substrates influence the rates of hydrolysis by these enzymes."}

{"project":"GlyCosmos15-Species","denotations":[{"id":"3","span":{"begin":124,"end":144},"obj":"Species"},{"id":"26","span":{"begin":327,"end":347},"obj":"Species"},{"id":"27","span":{"begin":366,"end":383},"obj":"Species"}],"attributes":[{"id":"A3","pred":"db_id","subj":"3","obj":"1911"},{"id":"A26","pred":"db_id","subj":"26","obj":"1911"}],"text":"The effects of N-substitution of chitosan and the physical form of the products on the rate of hydrolysis by chitinase from Streptomyces griseus.\nN-Formyl, N-chloroacetyl, N-glycyl, N-isobutyryl, and N-pentanoyl derivatives of chitosan have been prepared. N-Acetylchitosan was the derivative most susceptible to chitinase from Streptomyces griseus and lysozyme from chicken egg-white, but with respect to R in the RCOHN group were CH3 \u003e CH3CH2 \u003e H \u003e CH3CH2CH2 \u003e (CH3)2CH \u003e NH2CH2 \u003e CICH2. Neither enzyme hydrolysed chitosan or its N-methylene. N-benzylidene, N-benzoyl, N-nicotinyl, and N-fatty acyl (C5-C18) derivatives, and lysozyme did not hydrolyse N-butyrychitosan. N-Acetylhexanoyl-chitosans, which had d.s. ratios of approximately 0.7: approximately 0.3 and approximately 0.3: approximately 0.7, were hydrolysed at approximately 0.75 and approximately 0.004 of the rate of N-acetylchitosan (powder) by chitinase. O-Acylation of N-acylchitosans caused a decrease in the rates of hydrolysis by chitinase. N-Acetylchitosan gels were hydrolysed at 8-13 times the rate for crab-shell chitin. These results indicate that not only N- and O-substituents but also the physical form of the substrates influence the rates of hydrolysis by these enzymes."}

{"project":"Glycosmos6-MAT","denotations":[{"id":"T1","span":{"begin":374,"end":377},"obj":"http://purl.obolibrary.org/obo/MAT_0000213"}],"text":"The effects of N-substitution of chitosan and the physical form of the products on the rate of hydrolysis by chitinase from Streptomyces griseus.\nN-Formyl, N-chloroacetyl, N-glycyl, N-isobutyryl, and N-pentanoyl derivatives of chitosan have been prepared. N-Acetylchitosan was the derivative most susceptible to chitinase from Streptomyces griseus and lysozyme from chicken egg-white, but with respect to R in the RCOHN group were CH3 \u003e CH3CH2 \u003e H \u003e CH3CH2CH2 \u003e (CH3)2CH \u003e NH2CH2 \u003e CICH2. Neither enzyme hydrolysed chitosan or its N-methylene. N-benzylidene, N-benzoyl, N-nicotinyl, and N-fatty acyl (C5-C18) derivatives, and lysozyme did not hydrolyse N-butyrychitosan. N-Acetylhexanoyl-chitosans, which had d.s. ratios of approximately 0.7: approximately 0.3 and approximately 0.3: approximately 0.7, were hydrolysed at approximately 0.75 and approximately 0.004 of the rate of N-acetylchitosan (powder) by chitinase. O-Acylation of N-acylchitosans caused a decrease in the rates of hydrolysis by chitinase. N-Acetylchitosan gels were hydrolysed at 8-13 times the rate for crab-shell chitin. These results indicate that not only N- and O-substituents but also the physical form of the substrates influence the rates of hydrolysis by these enzymes."}

{"project":"sentences","denotations":[{"id":"TextSentencer_T1","span":{"begin":0,"end":145},"obj":"Sentence"},{"id":"TextSentencer_T2","span":{"begin":146,"end":255},"obj":"Sentence"},{"id":"TextSentencer_T3","span":{"begin":256,"end":488},"obj":"Sentence"},{"id":"TextSentencer_T4","span":{"begin":489,"end":543},"obj":"Sentence"},{"id":"TextSentencer_T5","span":{"begin":544,"end":670},"obj":"Sentence"},{"id":"TextSentencer_T6","span":{"begin":671,"end":919},"obj":"Sentence"},{"id":"TextSentencer_T7","span":{"begin":920,"end":1009},"obj":"Sentence"},{"id":"TextSentencer_T8","span":{"begin":1010,"end":1093},"obj":"Sentence"},{"id":"TextSentencer_T9","span":{"begin":1094,"end":1249},"obj":"Sentence"},{"id":"T1","span":{"begin":0,"end":145},"obj":"Sentence"},{"id":"T2","span":{"begin":146,"end":255},"obj":"Sentence"},{"id":"T3","span":{"begin":256,"end":488},"obj":"Sentence"},{"id":"T4","span":{"begin":489,"end":543},"obj":"Sentence"},{"id":"T5","span":{"begin":544,"end":670},"obj":"Sentence"},{"id":"T6","span":{"begin":671,"end":919},"obj":"Sentence"},{"id":"T7","span":{"begin":920,"end":1009},"obj":"Sentence"},{"id":"T8","span":{"begin":1010,"end":1093},"obj":"Sentence"},{"id":"T9","span":{"begin":1094,"end":1249},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"The effects of N-substitution of chitosan and the physical form of the products on the rate of hydrolysis by chitinase from Streptomyces griseus.\nN-Formyl, N-chloroacetyl, N-glycyl, N-isobutyryl, and N-pentanoyl derivatives of chitosan have been prepared. N-Acetylchitosan was the derivative most susceptible to chitinase from Streptomyces griseus and lysozyme from chicken egg-white, but with respect to R in the RCOHN group were CH3 \u003e CH3CH2 \u003e H \u003e CH3CH2CH2 \u003e (CH3)2CH \u003e NH2CH2 \u003e CICH2. Neither enzyme hydrolysed chitosan or its N-methylene. N-benzylidene, N-benzoyl, N-nicotinyl, and N-fatty acyl (C5-C18) derivatives, and lysozyme did not hydrolyse N-butyrychitosan. N-Acetylhexanoyl-chitosans, which had d.s. ratios of approximately 0.7: approximately 0.3 and approximately 0.3: approximately 0.7, were hydrolysed at approximately 0.75 and approximately 0.004 of the rate of N-acetylchitosan (powder) by chitinase. O-Acylation of N-acylchitosans caused a decrease in the rates of hydrolysis by chitinase. N-Acetylchitosan gels were hydrolysed at 8-13 times the rate for crab-shell chitin. These results indicate that not only N- and O-substituents but also the physical form of the substrates influence the rates of hydrolysis by these enzymes."}

{"project":"GlyCosmos15-Glycan","denotations":[{"id":"T1","span":{"begin":1086,"end":1092},"obj":"Glycan"}],"attributes":[{"id":"A1","pred":"glycosmos_id","subj":"T1","obj":"https://glycosmos.org/glycans/show/G97099AY"},{"id":"A2","pred":"image","subj":"T1","obj":"https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY"}],"text":"The effects of N-substitution of chitosan and the physical form of the products on the rate of hydrolysis by chitinase from Streptomyces griseus.\nN-Formyl, N-chloroacetyl, N-glycyl, N-isobutyryl, and N-pentanoyl derivatives of chitosan have been prepared. N-Acetylchitosan was the derivative most susceptible to chitinase from Streptomyces griseus and lysozyme from chicken egg-white, but with respect to R in the RCOHN group were CH3 \u003e CH3CH2 \u003e H \u003e CH3CH2CH2 \u003e (CH3)2CH \u003e NH2CH2 \u003e CICH2. Neither enzyme hydrolysed chitosan or its N-methylene. N-benzylidene, N-benzoyl, N-nicotinyl, and N-fatty acyl (C5-C18) derivatives, and lysozyme did not hydrolyse N-butyrychitosan. N-Acetylhexanoyl-chitosans, which had d.s. ratios of approximately 0.7: approximately 0.3 and approximately 0.3: approximately 0.7, were hydrolysed at approximately 0.75 and approximately 0.004 of the rate of N-acetylchitosan (powder) by chitinase. O-Acylation of N-acylchitosans caused a decrease in the rates of hydrolysis by chitinase. N-Acetylchitosan gels were hydrolysed at 8-13 times the rate for crab-shell chitin. These results indicate that not only N- and O-substituents but also the physical form of the substrates influence the rates of hydrolysis by these enzymes."}

{"project":"Glycan-GlyCosmos","denotations":[{"id":"T1","span":{"begin":1086,"end":1092},"obj":"Glycan"}],"attributes":[{"id":"A1","pred":"glycosmos_id","subj":"T1","obj":"https://glycosmos.org/glycans/show/G97099AY"},{"id":"A2","pred":"image","subj":"T1","obj":"https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY"}],"text":"The effects of N-substitution of chitosan and the physical form of the products on the rate of hydrolysis by chitinase from Streptomyces griseus.\nN-Formyl, N-chloroacetyl, N-glycyl, N-isobutyryl, and N-pentanoyl derivatives of chitosan have been prepared. N-Acetylchitosan was the derivative most susceptible to chitinase from Streptomyces griseus and lysozyme from chicken egg-white, but with respect to R in the RCOHN group were CH3 \u003e CH3CH2 \u003e H \u003e CH3CH2CH2 \u003e (CH3)2CH \u003e NH2CH2 \u003e CICH2. Neither enzyme hydrolysed chitosan or its N-methylene. N-benzylidene, N-benzoyl, N-nicotinyl, and N-fatty acyl (C5-C18) derivatives, and lysozyme did not hydrolyse N-butyrychitosan. N-Acetylhexanoyl-chitosans, which had d.s. ratios of approximately 0.7: approximately 0.3 and approximately 0.3: approximately 0.7, were hydrolysed at approximately 0.75 and approximately 0.004 of the rate of N-acetylchitosan (powder) by chitinase. O-Acylation of N-acylchitosans caused a decrease in the rates of hydrolysis by chitinase. N-Acetylchitosan gels were hydrolysed at 8-13 times the rate for crab-shell chitin. These results indicate that not only N- and O-substituents but also the physical form of the substrates influence the rates of hydrolysis by these enzymes."}

{"project":"GlyCosmos15-UBERON","denotations":[{"id":"T1","span":{"begin":374,"end":383},"obj":"Body_part"},{"id":"T2","span":{"begin":1080,"end":1085},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"uberon_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/UBERON_0008944"},{"id":"A2","pred":"uberon_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/UBERON_0006611"},{"id":"A3","pred":"uberon_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/UBERON_0006612"}],"text":"The effects of N-substitution of chitosan and the physical form of the products on the rate of hydrolysis by chitinase from Streptomyces griseus.\nN-Formyl, N-chloroacetyl, N-glycyl, N-isobutyryl, and N-pentanoyl derivatives of chitosan have been prepared. N-Acetylchitosan was the derivative most susceptible to chitinase from Streptomyces griseus and lysozyme from chicken egg-white, but with respect to R in the RCOHN group were CH3 \u003e CH3CH2 \u003e H \u003e CH3CH2CH2 \u003e (CH3)2CH \u003e NH2CH2 \u003e CICH2. Neither enzyme hydrolysed chitosan or its N-methylene. N-benzylidene, N-benzoyl, N-nicotinyl, and N-fatty acyl (C5-C18) derivatives, and lysozyme did not hydrolyse N-butyrychitosan. N-Acetylhexanoyl-chitosans, which had d.s. ratios of approximately 0.7: approximately 0.3 and approximately 0.3: approximately 0.7, were hydrolysed at approximately 0.75 and approximately 0.004 of the rate of N-acetylchitosan (powder) by chitinase. O-Acylation of N-acylchitosans caused a decrease in the rates of hydrolysis by chitinase. N-Acetylchitosan gels were hydrolysed at 8-13 times the rate for crab-shell chitin. These results indicate that not only N- and O-substituents but also the physical form of the substrates influence the rates of hydrolysis by these enzymes."}

{"project":"GlyCosmos15-Sentences","blocks":[{"id":"T1","span":{"begin":0,"end":145},"obj":"Sentence"},{"id":"T2","span":{"begin":146,"end":255},"obj":"Sentence"},{"id":"T3","span":{"begin":256,"end":488},"obj":"Sentence"},{"id":"T4","span":{"begin":489,"end":543},"obj":"Sentence"},{"id":"T5","span":{"begin":544,"end":670},"obj":"Sentence"},{"id":"T6","span":{"begin":671,"end":919},"obj":"Sentence"},{"id":"T7","span":{"begin":920,"end":1009},"obj":"Sentence"},{"id":"T8","span":{"begin":1010,"end":1093},"obj":"Sentence"},{"id":"T9","span":{"begin":1094,"end":1249},"obj":"Sentence"}],"text":"The effects of N-substitution of chitosan and the physical form of the products on the rate of hydrolysis by chitinase from Streptomyces griseus.\nN-Formyl, N-chloroacetyl, N-glycyl, N-isobutyryl, and N-pentanoyl derivatives of chitosan have been prepared. N-Acetylchitosan was the derivative most susceptible to chitinase from Streptomyces griseus and lysozyme from chicken egg-white, but with respect to R in the RCOHN group were CH3 \u003e CH3CH2 \u003e H \u003e CH3CH2CH2 \u003e (CH3)2CH \u003e NH2CH2 \u003e CICH2. Neither enzyme hydrolysed chitosan or its N-methylene. N-benzylidene, N-benzoyl, N-nicotinyl, and N-fatty acyl (C5-C18) derivatives, and lysozyme did not hydrolyse N-butyrychitosan. N-Acetylhexanoyl-chitosans, which had d.s. ratios of approximately 0.7: approximately 0.3 and approximately 0.3: approximately 0.7, were hydrolysed at approximately 0.75 and approximately 0.004 of the rate of N-acetylchitosan (powder) by chitinase. O-Acylation of N-acylchitosans caused a decrease in the rates of hydrolysis by chitinase. N-Acetylchitosan gels were hydrolysed at 8-13 times the rate for crab-shell chitin. These results indicate that not only N- and O-substituents but also the physical form of the substrates influence the rates of hydrolysis by these enzymes."}

{"project":"GlyCosmos15-MAT","denotations":[{"id":"T1","span":{"begin":374,"end":377},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"mat_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/MAT_0000213"}],"text":"The effects of N-substitution of chitosan and the physical form of the products on the rate of hydrolysis by chitinase from Streptomyces griseus.\nN-Formyl, N-chloroacetyl, N-glycyl, N-isobutyryl, and N-pentanoyl derivatives of chitosan have been prepared. N-Acetylchitosan was the derivative most susceptible to chitinase from Streptomyces griseus and lysozyme from chicken egg-white, but with respect to R in the RCOHN group were CH3 \u003e CH3CH2 \u003e H \u003e CH3CH2CH2 \u003e (CH3)2CH \u003e NH2CH2 \u003e CICH2. Neither enzyme hydrolysed chitosan or its N-methylene. N-benzylidene, N-benzoyl, N-nicotinyl, and N-fatty acyl (C5-C18) derivatives, and lysozyme did not hydrolyse N-butyrychitosan. N-Acetylhexanoyl-chitosans, which had d.s. ratios of approximately 0.7: approximately 0.3 and approximately 0.3: approximately 0.7, were hydrolysed at approximately 0.75 and approximately 0.004 of the rate of N-acetylchitosan (powder) by chitinase. O-Acylation of N-acylchitosans caused a decrease in the rates of hydrolysis by chitinase. N-Acetylchitosan gels were hydrolysed at 8-13 times the rate for crab-shell chitin. These results indicate that not only N- and O-substituents but also the physical form of the substrates influence the rates of hydrolysis by these enzymes."}

{"project":"NCBITAXON","denotations":[{"id":"T1","span":{"begin":124,"end":144},"obj":"OrganismTaxon"},{"id":"T2","span":{"begin":327,"end":347},"obj":"OrganismTaxon"}],"attributes":[{"id":"A1","pred":"db_id","subj":"T1","obj":"1911"},{"id":"A2","pred":"db_id","subj":"T2","obj":"1911"}],"text":"The effects of N-substitution of chitosan and the physical form of the products on the rate of hydrolysis by chitinase from Streptomyces griseus.\nN-Formyl, N-chloroacetyl, N-glycyl, N-isobutyryl, and N-pentanoyl derivatives of chitosan have been prepared. N-Acetylchitosan was the derivative most susceptible to chitinase from Streptomyces griseus and lysozyme from chicken egg-white, but with respect to R in the RCOHN group were CH3 \u003e CH3CH2 \u003e H \u003e CH3CH2CH2 \u003e (CH3)2CH \u003e NH2CH2 \u003e CICH2. Neither enzyme hydrolysed chitosan or its N-methylene. N-benzylidene, N-benzoyl, N-nicotinyl, and N-fatty acyl (C5-C18) derivatives, and lysozyme did not hydrolyse N-butyrychitosan. N-Acetylhexanoyl-chitosans, which had d.s. ratios of approximately 0.7: approximately 0.3 and approximately 0.3: approximately 0.7, were hydrolysed at approximately 0.75 and approximately 0.004 of the rate of N-acetylchitosan (powder) by chitinase. O-Acylation of N-acylchitosans caused a decrease in the rates of hydrolysis by chitinase. N-Acetylchitosan gels were hydrolysed at 8-13 times the rate for crab-shell chitin. These results indicate that not only N- and O-substituents but also the physical form of the substrates influence the rates of hydrolysis by these enzymes."}

{"project":"Anatomy-UBERON","denotations":[{"id":"T1","span":{"begin":374,"end":383},"obj":"Body_part"},{"id":"T2","span":{"begin":1080,"end":1085},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"uberon_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/UBERON_0008944"},{"id":"A2","pred":"uberon_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/UBERON_0006611"},{"id":"A3","pred":"uberon_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/UBERON_0006612"}],"text":"The effects of N-substitution of chitosan and the physical form of the products on the rate of hydrolysis by chitinase from Streptomyces griseus.\nN-Formyl, N-chloroacetyl, N-glycyl, N-isobutyryl, and N-pentanoyl derivatives of chitosan have been prepared. N-Acetylchitosan was the derivative most susceptible to chitinase from Streptomyces griseus and lysozyme from chicken egg-white, but with respect to R in the RCOHN group were CH3 \u003e CH3CH2 \u003e H \u003e CH3CH2CH2 \u003e (CH3)2CH \u003e NH2CH2 \u003e CICH2. Neither enzyme hydrolysed chitosan or its N-methylene. N-benzylidene, N-benzoyl, N-nicotinyl, and N-fatty acyl (C5-C18) derivatives, and lysozyme did not hydrolyse N-butyrychitosan. N-Acetylhexanoyl-chitosans, which had d.s. ratios of approximately 0.7: approximately 0.3 and approximately 0.3: approximately 0.7, were hydrolysed at approximately 0.75 and approximately 0.004 of the rate of N-acetylchitosan (powder) by chitinase. O-Acylation of N-acylchitosans caused a decrease in the rates of hydrolysis by chitinase. N-Acetylchitosan gels were hydrolysed at 8-13 times the rate for crab-shell chitin. These results indicate that not only N- and O-substituents but also the physical form of the substrates influence the rates of hydrolysis by these enzymes."}

{"project":"Anatomy-MAT","denotations":[{"id":"T1","span":{"begin":374,"end":377},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"mat_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/MAT_0000213"}],"text":"The effects of N-substitution of chitosan and the physical form of the products on the rate of hydrolysis by chitinase from Streptomyces griseus.\nN-Formyl, N-chloroacetyl, N-glycyl, N-isobutyryl, and N-pentanoyl derivatives of chitosan have been prepared. N-Acetylchitosan was the derivative most susceptible to chitinase from Streptomyces griseus and lysozyme from chicken egg-white, but with respect to R in the RCOHN group were CH3 \u003e CH3CH2 \u003e H \u003e CH3CH2CH2 \u003e (CH3)2CH \u003e NH2CH2 \u003e CICH2. Neither enzyme hydrolysed chitosan or its N-methylene. N-benzylidene, N-benzoyl, N-nicotinyl, and N-fatty acyl (C5-C18) derivatives, and lysozyme did not hydrolyse N-butyrychitosan. N-Acetylhexanoyl-chitosans, which had d.s. ratios of approximately 0.7: approximately 0.3 and approximately 0.3: approximately 0.7, were hydrolysed at approximately 0.75 and approximately 0.004 of the rate of N-acetylchitosan (powder) by chitinase. O-Acylation of N-acylchitosans caused a decrease in the rates of hydrolysis by chitinase. N-Acetylchitosan gels were hydrolysed at 8-13 times the rate for crab-shell chitin. These results indicate that not only N- and O-substituents but also the physical form of the substrates influence the rates of hydrolysis by these enzymes."}