PubMed:6193847 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/6193847","sourcedb":"PubMed","sourceid":"6193847","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/6193847","text":"[Fractionation of a sciatic nerve homogenate from normal, trembler and quaking mice on a continuous sucrose gradient].\nTwo fractions, characterized by biochemical criteria [quantity and density of particulate material, localization of myelin specific protein--Po, P1 and Pr--and of 2',3'-cyclic nucleotide 3'-phosphohydrolase (CNP) and of 5'-nucleotidase], were isolated from sciatic nerve homogenate of normal, Trembler and quaking, young and adult Mice, on a continuous sucrose gradient. The fraction, at 0.58-0.6 M, the richest in membrane particles contains the myelin. The fraction at 0.7-0.75 M should contain the plasma membrane of the Schwann cell which synthesizes myelin.","tracks":[{"project":"QFMC_MEDLINE","denotations":[{"id":"T1","span":{"begin":130,"end":188},"obj":"ANAT"},{"id":"T1c","span":{"begin":130,"end":188},"obj":"UMLS:C0036394"},{"id":"T2","span":{"begin":130,"end":147},"obj":"ANAT"},{"id":"T2c","span":{"begin":130,"end":147},"obj":"UMLS:C0027740"},{"id":"T3","span":{"begin":312,"end":400},"obj":"LIVB"},{"id":"T3c","span":{"begin":312,"end":400},"obj":"UMLS:C0025929"},{"id":"T4","span":{"begin":312,"end":364},"obj":"LIVB"},{"id":"T4c","span":{"begin":312,"end":364},"obj":"UMLS:C0025934"},{"id":"T4","span":{"begin":425,"end":432},"obj":"LIVB"},{"id":"T4c","span":{"begin":425,"end":432},"obj":"UMLS:C0025934"},{"id":"T5","span":{"begin":551,"end":668},"obj":"CHEM"},{"id":"T5c","span":{"begin":551,"end":668},"obj":"UMLS:C0038636"},{"id":"T6","span":{"begin":312,"end":364},"obj":"LIVB"},{"id":"T6c","span":{"begin":312,"end":364},"obj":"UMLS:C0025932"},{"id":"T6","span":{"begin":412,"end":420},"obj":"LIVB"},{"id":"T6c","span":{"begin":412,"end":420},"obj":"UMLS:C0025932"}],"relations":[{"id":"#1","pred":"Normalization","subj":"T1","obj":"T1c"},{"id":"#2","pred":"Normalization","subj":"T2","obj":"T2c"},{"id":"#3","pred":"Normalization","subj":"T3","obj":"T3c"},{"id":"#4","pred":"Normalization","subj":"T4","obj":"T4c"},{"id":"#4","pred":"Normalization","subj":"T4","obj":"T4c"},{"id":"#5","pred":"Normalization","subj":"T5","obj":"T5c"},{"id":"#6","pred":"Normalization","subj":"T6","obj":"T6c"},{"id":"#6","pred":"Normalization","subj":"T6","obj":"T6c"}],"namespaces":[{"prefix":"UMLS","uri":"https://uts.nlm.nih.gov/metathesaurus.html#"}],"attributes":[{"subj":"T1","pred":"source","obj":"QFMC_MEDLINE"},{"subj":"T1c","pred":"source","obj":"QFMC_MEDLINE"},{"subj":"T2","pred":"source","obj":"QFMC_MEDLINE"},{"subj":"T2c","pred":"source","obj":"QFMC_MEDLINE"},{"subj":"T3","pred":"source","obj":"QFMC_MEDLINE"},{"subj":"T3c","pred":"source","obj":"QFMC_MEDLINE"},{"subj":"T4","pred":"source","obj":"QFMC_MEDLINE"},{"subj":"T4c","pred":"source","obj":"QFMC_MEDLINE"},{"subj":"T4","pred":"source","obj":"QFMC_MEDLINE"},{"subj":"T4c","pred":"source","obj":"QFMC_MEDLINE"},{"subj":"T5","pred":"source","obj":"QFMC_MEDLINE"},{"subj":"T5c","pred":"source","obj":"QFMC_MEDLINE"},{"subj":"T6","pred":"source","obj":"QFMC_MEDLINE"},{"subj":"T6c","pred":"source","obj":"QFMC_MEDLINE"},{"subj":"T6","pred":"source","obj":"QFMC_MEDLINE"},{"subj":"T6c","pred":"source","obj":"QFMC_MEDLINE"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"QFMC_MEDLINE","color":"#b293ec","default":true}]}]}}