| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1 |
0-50 |
Sentence |
denotes |
Cutaneous reactions to intradermal prostaglandins. |
| T2 |
51-53 |
Sentence |
denotes |
1. |
| T3 |
54-192 |
Sentence |
denotes |
The effects of intradermally injected prostaglandins (PGs) E(1), E(2), F(1alpha) and F(2alpha) have been examined in the rat and in man.2. |
| T4 |
193-491 |
Sentence |
denotes |
PGE(1) and PGE(2) caused an increase in local vascular permeability in rat skin; their potency was comparable with that of other putative mediators of inflammation (histamine, bradykinin, and 5-hydroxytryptamine), but PGF(1alpha) and PGF(2alpha) were only slightly active even at a dose of 1 mug.3. |
| T5 |
492-704 |
Sentence |
denotes |
Prior administration of mepyramine and methysergide, or depletion of skin mast cell amines with compound 48/80, indicated that PGE(2) exerted its permeability effect in the rat by a release of mast cell amines.4. |
| T6 |
705-876 |
Sentence |
denotes |
Nanogramme doses of PGE(1) and PGE(2) or microgramme doses of PGF(1alpha) and PGF(2alpha) injected intradermally into the human forearm induced weal and flare responses.5. |
| T7 |
877-1041 |
Sentence |
denotes |
It is concluded that prostaglandins E(1) and E(2) can act as intermediates in the production of hyperaemia and oedema resulting from cell damage in the rat and man. |
| T1 |
0-50 |
Sentence |
denotes |
Cutaneous reactions to intradermal prostaglandins. |
| T2 |
51-53 |
Sentence |
denotes |
1. |
| T3 |
54-192 |
Sentence |
denotes |
The effects of intradermally injected prostaglandins (PGs) E(1), E(2), F(1alpha) and F(2alpha) have been examined in the rat and in man.2. |
| T4 |
193-491 |
Sentence |
denotes |
PGE(1) and PGE(2) caused an increase in local vascular permeability in rat skin; their potency was comparable with that of other putative mediators of inflammation (histamine, bradykinin, and 5-hydroxytryptamine), but PGF(1alpha) and PGF(2alpha) were only slightly active even at a dose of 1 mug.3. |
| T5 |
492-704 |
Sentence |
denotes |
Prior administration of mepyramine and methysergide, or depletion of skin mast cell amines with compound 48/80, indicated that PGE(2) exerted its permeability effect in the rat by a release of mast cell amines.4. |
| T6 |
705-876 |
Sentence |
denotes |
Nanogramme doses of PGE(1) and PGE(2) or microgramme doses of PGF(1alpha) and PGF(2alpha) injected intradermally into the human forearm induced weal and flare responses.5. |
| T7 |
877-1041 |
Sentence |
denotes |
It is concluded that prostaglandins E(1) and E(2) can act as intermediates in the production of hyperaemia and oedema resulting from cell damage in the rat and man. |