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PubMed:4092214 JSON TXT

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sentences

Id	Subject	Object	Predicate	Lexical cue
TextSentencer_T1	0-45	Sentence	denotes	Reaction of human serum albumin with aldoses.
TextSentencer_T2	46-143	Sentence	denotes	The reaction of human serum albumin (HSA) with aldoses (C3-C6) and acetaldehyde has been studied.
TextSentencer_T3	144-294	Sentence	denotes	U.v. and fluorescent spectra of the HSA-glyceraldehyde and HSA-GlcN adducts reveal yellow chromophores absorbing at 300-350 nm and emitting at 435 nm.
TextSentencer_T4	295-400	Sentence	denotes	However, even limited reaction of HSA with acetaldehyde induced perturbation in the Trp microenvironment.
TextSentencer_T5	401-568	Sentence	denotes	C.d. spectra of the adducts show an average 20% decrement in mean residual ellipticity [theta], which is independent of the extent of the reaction and the aldose used.
TextSentencer_T6	569-666	Sentence	denotes	It is concluded that most of the reactions with aldoses occur at the surface of the HSA molecule.
TextSentencer_T7	667-780	Sentence	denotes	With the exception of the GlcN adduct, the HSA adducts rearrange to produce pyrrole rings on the protein surface.
TextSentencer_T8	781-980	Sentence	denotes	I.e.f. analysis shows that the pI values of the modified HSA are almost linearly correlated with the chain length of the reacting aldose: from pI 4.2 for HSA-glyceraldehyde up to pI 5.0 for HSA-GlcN.
T1	0-45	Sentence	denotes	Reaction of human serum albumin with aldoses.
T2	46-143	Sentence	denotes	The reaction of human serum albumin (HSA) with aldoses (C3-C6) and acetaldehyde has been studied.
T3	144-294	Sentence	denotes	U.v. and fluorescent spectra of the HSA-glyceraldehyde and HSA-GlcN adducts reveal yellow chromophores absorbing at 300-350 nm and emitting at 435 nm.
T4	295-400	Sentence	denotes	However, even limited reaction of HSA with acetaldehyde induced perturbation in the Trp microenvironment.
T5	401-568	Sentence	denotes	C.d. spectra of the adducts show an average 20% decrement in mean residual ellipticity [theta], which is independent of the extent of the reaction and the aldose used.
T6	569-666	Sentence	denotes	It is concluded that most of the reactions with aldoses occur at the surface of the HSA molecule.
T7	667-780	Sentence	denotes	With the exception of the GlcN adduct, the HSA adducts rearrange to produce pyrrole rings on the protein surface.
T8	781-980	Sentence	denotes	I.e.f. analysis shows that the pI values of the modified HSA are almost linearly correlated with the chain length of the reacting aldose: from pI 4.2 for HSA-glyceraldehyde up to pI 5.0 for HSA-GlcN.

mondo_disease

Id	Subject	Object	Predicate	Lexical cue	mondo_id
T1	83-86	Disease	denotes	HSA	http://purl.obolibrary.org/obo/MONDO_0011848
T2	180-183	Disease	denotes	HSA	http://purl.obolibrary.org/obo/MONDO_0011848
T3	203-206	Disease	denotes	HSA	http://purl.obolibrary.org/obo/MONDO_0011848
T4	329-332	Disease	denotes	HSA	http://purl.obolibrary.org/obo/MONDO_0011848
T5	653-656	Disease	denotes	HSA	http://purl.obolibrary.org/obo/MONDO_0011848
T6	710-713	Disease	denotes	HSA	http://purl.obolibrary.org/obo/MONDO_0011848
T7	838-841	Disease	denotes	HSA	http://purl.obolibrary.org/obo/MONDO_0011848
T8	935-938	Disease	denotes	HSA	http://purl.obolibrary.org/obo/MONDO_0011848
T9	971-974	Disease	denotes	HSA	http://purl.obolibrary.org/obo/MONDO_0011848

NCBITAXON

Id	Subject	Object	Predicate	Lexical cue	db_id
T1	12-17	OrganismTaxon	denotes	human	9606
T2	62-67	OrganismTaxon	denotes	human	9606