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GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 165-172 Glycan_Motif denotes heparin https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G54161DR|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00021MO
T3 367-374 Glycan_Motif denotes heparin https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G54161DR|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00021MO
T5 394-415 Glycan_Motif denotes chondroitin 6-sulfate https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G34992DF
T6 394-405 Glycan_Motif denotes chondroitin https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT
T7 652-659 Glycan_Motif denotes heparin https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G54161DR|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00021MO
T9 664-675 Glycan_Motif denotes chondroitin https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT
T10 843-850 Glycan_Motif denotes heparin https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G54161DR|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00021MO
T12 889-900 Glycan_Motif denotes chondroitin https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT

Glycosmos6-GlycoEpitope

Id Subject Object Predicate Lexical cue
T1 394-415 http://www.glycoepitope.jp/epitopes/EP0083 denotes chondroitin 6-sulfate
T2 394-405 http://www.glycoepitope.jp/epitopes/EP0081 denotes chondroitin
T3 664-675 http://www.glycoepitope.jp/epitopes/EP0081 denotes chondroitin
T4 889-900 http://www.glycoepitope.jp/epitopes/EP0081 denotes chondroitin

sentences

Id Subject Object Predicate Lexical cue
T1 0-82 Sentence denotes A sulfatase specific for glucuronic acid 2-sulfate residues in glycosaminoglycans.
T2 83-269 Sentence denotes Although 2-O-sulfated L-iduronic acid (IdoA) residues have been known to occur in heparin, 2-O-sulfated D-glucuronic acid (GlcA) residues have been reported only recently (Bienkowski, M.
T3 270-288 Sentence denotes J., and Conrad, H.
T4 289-301 Sentence denotes E. (1985) J.
T5 302-307 Sentence denotes Biol.
T6 308-313 Sentence denotes Chem.
T7 314-328 Sentence denotes 250, 356-365).
T8 329-566 Sentence denotes Disaccharides prepared by cleavage of heparin and N-deacetylated chondroitin 6-sulfate with nitrous acid were used to demonstrate a new sulfatase that catalyzed the removal of the 2-O-sulfate substituents from GlcA but not IdoA residues.
T9 567-808 Sentence denotes The deamination products were labeled by NaB3H4 reduction to give disaccharides from heparin and chondroitin sulfate which had reducing terminal 2,5-anhydro-D-mannitol ([3H]AManR) and 2,5-anhydro-D-talitol ([3H]ATalR) residues, respectively.
T10 809-945 Sentence denotes IdoA(2-SO4)-[3H]AManR(6-SO4) from heparin and GlcA(2-SO4)-[3H]ATalR(6-SO4) from chondroitin sulfate were purified for use as substrates.
T11 946-1069 Sentence denotes GlcA(2-SO4)-[3H]AManR(6-SO4) was prepared by epimerization of IdoA(2-SO4)-[3H]AManR(6-SO4) with hydrazine at 100 degrees C.
T12 1070-1355 Sentence denotes Lysosomal enzyme preparations from chick embryo chondrocytes and from two normal human fibroblast cell lines catalyzed the removal of the 2-O-SO4 substituent from the uronic acid residues of IdoA(2-SO4)-[3H]AManR(6-SO4), GlcA(2-SO4)-[3H] AManR(6-SO4), and GlcA(2-SO4)-[3H]ATalR(6-SO4).
T13 1356-1646 Sentence denotes In contrast, a lysosomal enzyme preparation from a human fibroblast cell line deficient in idurono-2-sulfatase (Hunter's-syndrome), which had no activity on the IdoA(2-SO4)-[3H]AManR(6-SO4), converted GlcA(2-SO4)-[3H]AManR(6-SO4) to a mixture of GlcA-[3H] AManR(6-SO4) and [3H]AManR(6-SO4).
T14 1647-1762 Sentence denotes This enzyme also converted GlcA(2-SO4)-[3H]ATalR(6-SO4) to a mixture of GlcA-[3H]ATalR(6-SO4) and [3H]ATalR(6-SO4).
T15 1763-1947 Sentence denotes Digestion of both GlcA(2-SO4)-[3H]AManR(6-SO4) and GlcA(2-SO4)-[3H]ATalR(6-SO4) was inhibited by 35SO2-4 and was arrested at the monosulfated disaccharide stage by 1,4-saccharolactone.
T16 1948-2002 Sentence denotes The glucurono-2-sulfatase exhibited a pH optimum of 4.
T17 2003-2151 Sentence denotes The results indicate that there exists a separate sulfatase for the removal of sulfate substituents from C-2 of GlcA residues in glycosaminoglycans.
T1 0-82 Sentence denotes A sulfatase specific for glucuronic acid 2-sulfate residues in glycosaminoglycans.
T2 83-269 Sentence denotes Although 2-O-sulfated L-iduronic acid (IdoA) residues have been known to occur in heparin, 2-O-sulfated D-glucuronic acid (GlcA) residues have been reported only recently (Bienkowski, M.
T3 270-288 Sentence denotes J., and Conrad, H.
T4 289-301 Sentence denotes E. (1985) J.
T5 302-307 Sentence denotes Biol.
T6 308-313 Sentence denotes Chem.
T7 314-328 Sentence denotes 250, 356-365).
T8 329-566 Sentence denotes Disaccharides prepared by cleavage of heparin and N-deacetylated chondroitin 6-sulfate with nitrous acid were used to demonstrate a new sulfatase that catalyzed the removal of the 2-O-sulfate substituents from GlcA but not IdoA residues.
T9 567-808 Sentence denotes The deamination products were labeled by NaB3H4 reduction to give disaccharides from heparin and chondroitin sulfate which had reducing terminal 2,5-anhydro-D-mannitol ([3H]AManR) and 2,5-anhydro-D-talitol ([3H]ATalR) residues, respectively.
T10 809-945 Sentence denotes IdoA(2-SO4)-[3H]AManR(6-SO4) from heparin and GlcA(2-SO4)-[3H]ATalR(6-SO4) from chondroitin sulfate were purified for use as substrates.
T11 946-1069 Sentence denotes GlcA(2-SO4)-[3H]AManR(6-SO4) was prepared by epimerization of IdoA(2-SO4)-[3H]AManR(6-SO4) with hydrazine at 100 degrees C.
T12 1070-1355 Sentence denotes Lysosomal enzyme preparations from chick embryo chondrocytes and from two normal human fibroblast cell lines catalyzed the removal of the 2-O-SO4 substituent from the uronic acid residues of IdoA(2-SO4)-[3H]AManR(6-SO4), GlcA(2-SO4)-[3H] AManR(6-SO4), and GlcA(2-SO4)-[3H]ATalR(6-SO4).
T13 1356-1646 Sentence denotes In contrast, a lysosomal enzyme preparation from a human fibroblast cell line deficient in idurono-2-sulfatase (Hunter's-syndrome), which had no activity on the IdoA(2-SO4)-[3H]AManR(6-SO4), converted GlcA(2-SO4)-[3H]AManR(6-SO4) to a mixture of GlcA-[3H] AManR(6-SO4) and [3H]AManR(6-SO4).
T14 1647-1762 Sentence denotes This enzyme also converted GlcA(2-SO4)-[3H]ATalR(6-SO4) to a mixture of GlcA-[3H]ATalR(6-SO4) and [3H]ATalR(6-SO4).
T15 1763-1947 Sentence denotes Digestion of both GlcA(2-SO4)-[3H]AManR(6-SO4) and GlcA(2-SO4)-[3H]ATalR(6-SO4) was inhibited by 35SO2-4 and was arrested at the monosulfated disaccharide stage by 1,4-saccharolactone.
T16 1948-2002 Sentence denotes The glucurono-2-sulfatase exhibited a pH optimum of 4.
T17 2003-2151 Sentence denotes The results indicate that there exists a separate sulfatase for the removal of sulfate substituents from C-2 of GlcA residues in glycosaminoglycans.

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 165-172 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T2 165-172 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin
T3 367-374 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T4 367-374 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin
T5 394-415 https://glytoucan.org/Structures/Glycans/G34992DF denotes chondroitin 6-sulfate
T6 394-405 https://glytoucan.org/Structures/Glycans/G43702JT denotes chondroitin
T7 652-659 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T8 652-659 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin
T9 664-675 https://glytoucan.org/Structures/Glycans/G43702JT denotes chondroitin
T10 843-850 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T11 843-850 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin
T12 889-900 https://glytoucan.org/Structures/Glycans/G43702JT denotes chondroitin

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 1111-1117 http://purl.obolibrary.org/obo/MAT_0000226 denotes embryo

bionlp-st-pc-2013-training

Id Subject Object Predicate Lexical cue
T1 25-50 Simple_chemical denotes glucuronic acid 2-sulfate
T2 63-81 Simple_chemical denotes glycosaminoglycans
T3 105-120 Simple_chemical denotes L-iduronic acid
T4 122-126 Simple_chemical denotes IdoA
T5 165-172 Simple_chemical denotes heparin
T6 187-204 Simple_chemical denotes D-glucuronic acid
T7 206-210 Simple_chemical denotes GlcA
T8 367-374 Simple_chemical denotes heparin
T9 394-415 Simple_chemical denotes chondroitin 6-sulfate
T10 421-433 Simple_chemical denotes nitrous acid
T11 509-520 Simple_chemical denotes 2-O-sulfate
T12 539-543 Simple_chemical denotes GlcA
T13 552-556 Simple_chemical denotes IdoA
T14 608-614 Simple_chemical denotes NaB3H4
T15 652-659 Simple_chemical denotes heparin
T16 664-683 Simple_chemical denotes chondroitin sulfate
T17 712-734 Simple_chemical denotes 2,5-anhydro-D-mannitol
T18 736-745 Simple_chemical denotes [3H]AManR
T19 751-772 Simple_chemical denotes 2,5-anhydro-D-talitol
T20 774-783 Simple_chemical denotes [3H]ATalR
T21 809-837 Simple_chemical denotes IdoA(2-SO4)-[3H]AManR(6-SO4)
T22 843-850 Simple_chemical denotes heparin
T23 855-883 Simple_chemical denotes GlcA(2-SO4)-[3H]ATalR(6-SO4)
T24 889-908 Simple_chemical denotes chondroitin sulfate
T25 946-974 Simple_chemical denotes GlcA(2-SO4)-[3H]AManR(6-SO4)
T26 1008-1036 Simple_chemical denotes IdoA(2-SO4)-[3H]AManR(6-SO4)
T27 1042-1051 Simple_chemical denotes hydrazine
T28 1070-1079 Cellular_component denotes Lysosomal
T29 1208-1215 Simple_chemical denotes 2-O-SO4
T30 1237-1248 Simple_chemical denotes uronic acid
T31 1261-1289 Simple_chemical denotes IdoA(2-SO4)-[3H]AManR(6-SO4)
T32 1291-1320 Simple_chemical denotes GlcA(2-SO4)-[3H] AManR(6-SO4)
T33 1326-1354 Simple_chemical denotes GlcA(2-SO4)-[3H]ATalR(6-SO4)
T34 1371-1380 Cellular_component denotes lysosomal
T35 1447-1466 Gene_or_gene_product denotes idurono-2-sulfatase
T36 1517-1545 Simple_chemical denotes IdoA(2-SO4)-[3H]AManR(6-SO4)
T37 1557-1585 Simple_chemical denotes GlcA(2-SO4)-[3H]AManR(6-SO4)
T38 1602-1624 Simple_chemical denotes GlcA-[3H] AManR(6-SO4)
T39 1629-1645 Simple_chemical denotes [3H]AManR(6-SO4)
T40 1674-1702 Simple_chemical denotes GlcA(2-SO4)-[3H]ATalR(6-SO4)
T41 1719-1740 Simple_chemical denotes GlcA-[3H]ATalR(6-SO4)
T42 1745-1761 Simple_chemical denotes [3H]ATalR(6-SO4)
T43 1781-1809 Simple_chemical denotes GlcA(2-SO4)-[3H]AManR(6-SO4)
T44 1814-1842 Simple_chemical denotes GlcA(2-SO4)-[3H]ATalR(6-SO4)
T45 1860-1867 Simple_chemical denotes 35SO2-4
T46 1892-1917 Simple_chemical denotes monosulfated disaccharide
T47 1927-1946 Simple_chemical denotes 1,4-saccharolactone
T48 1952-1973 Gene_or_gene_product denotes glucurono-2-sulfatase
T49 2082-2089 Simple_chemical denotes sulfate
T50 2108-2111 Simple_chemical denotes C-2
T51 2115-2119 Simple_chemical denotes GlcA
T52 2132-2150 Simple_chemical denotes glycosaminoglycans

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 1111-1117 Body_part denotes embryo http://purl.obolibrary.org/obo/MAT_0000226

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 1468-1485 Disease denotes Hunter's-syndrome http://purl.obolibrary.org/obo/MONDO_0010674

Glycan-GlyCosmos

Id Subject Object Predicate Lexical cue image
T1 394-415 Glycan denotes chondroitin 6-sulfate https://api.glycosmos.org/wurcs2image/latest/png/binary/G34992DF
T2 664-675 Glycan denotes chondroitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT
T3 889-900 Glycan denotes chondroitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT

GlyCosmos-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 394-415 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes chondroitin 6-sulfate http://www.glycoepitope.jp/epitopes/EP0083
T2 664-675 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes chondroitin http://www.glycoepitope.jp/epitopes/EP0081
T3 889-900 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes chondroitin http://www.glycoepitope.jp/epitopes/EP0081

GlyCosmos15-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 1468-1485 Disease denotes Hunter's-syndrome http://purl.obolibrary.org/obo/MONDO_0010674

GlyCosmos15-NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 1151-1156 OrganismTaxon denotes human 9606
T2 1407-1412 OrganismTaxon denotes human 9606

GlyCosmos15-CL

Id Subject Object Predicate Lexical cue cl_id
T1 1118-1130 Cell denotes chondrocytes http://purl.obolibrary.org/obo/CL:0000138
T2 1157-1167 Cell denotes fibroblast http://purl.obolibrary.org/obo/CL:0000057
T3 1413-1423 Cell denotes fibroblast http://purl.obolibrary.org/obo/CL:0000057

GlyCosmos15-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 1111-1117 Body_part denotes embryo http://purl.obolibrary.org/obo/UBERON_0000922
T2 1118-1130 Body_part denotes chondrocytes http://purl.obolibrary.org/obo/CL_0000138
T3 1157-1167 Body_part denotes fibroblast http://purl.obolibrary.org/obo/CL_0000057
T4 1413-1423 Body_part denotes fibroblast http://purl.obolibrary.org/obo/CL_0000057

GlyCosmos15-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 1111-1117 Body_part denotes embryo http://purl.obolibrary.org/obo/MAT_0000226

sentences

Id Subject Object Predicate Lexical cue
T1 0-82 Sentence denotes A sulfatase specific for glucuronic acid 2-sulfate residues in glycosaminoglycans.
T2 83-269 Sentence denotes Although 2-O-sulfated L-iduronic acid (IdoA) residues have been known to occur in heparin, 2-O-sulfated D-glucuronic acid (GlcA) residues have been reported only recently (Bienkowski, M.
T3 270-288 Sentence denotes J., and Conrad, H.
T4 289-301 Sentence denotes E. (1985) J.
T5 302-307 Sentence denotes Biol.
T6 308-313 Sentence denotes Chem.
T7 314-328 Sentence denotes 250, 356-365).
T8 329-566 Sentence denotes Disaccharides prepared by cleavage of heparin and N-deacetylated chondroitin 6-sulfate with nitrous acid were used to demonstrate a new sulfatase that catalyzed the removal of the 2-O-sulfate substituents from GlcA but not IdoA residues.
T9 567-808 Sentence denotes The deamination products were labeled by NaB3H4 reduction to give disaccharides from heparin and chondroitin sulfate which had reducing terminal 2,5-anhydro-D-mannitol ([3H]AManR) and 2,5-anhydro-D-talitol ([3H]ATalR) residues, respectively.
T10 809-945 Sentence denotes IdoA(2-SO4)-[3H]AManR(6-SO4) from heparin and GlcA(2-SO4)-[3H]ATalR(6-SO4) from chondroitin sulfate were purified for use as substrates.
T11 946-1069 Sentence denotes GlcA(2-SO4)-[3H]AManR(6-SO4) was prepared by epimerization of IdoA(2-SO4)-[3H]AManR(6-SO4) with hydrazine at 100 degrees C.
T12 1070-1355 Sentence denotes Lysosomal enzyme preparations from chick embryo chondrocytes and from two normal human fibroblast cell lines catalyzed the removal of the 2-O-SO4 substituent from the uronic acid residues of IdoA(2-SO4)-[3H]AManR(6-SO4), GlcA(2-SO4)-[3H] AManR(6-SO4), and GlcA(2-SO4)-[3H]ATalR(6-SO4).
T13 1356-1646 Sentence denotes In contrast, a lysosomal enzyme preparation from a human fibroblast cell line deficient in idurono-2-sulfatase (Hunter's-syndrome), which had no activity on the IdoA(2-SO4)-[3H]AManR(6-SO4), converted GlcA(2-SO4)-[3H]AManR(6-SO4) to a mixture of GlcA-[3H] AManR(6-SO4) and [3H]AManR(6-SO4).
T14 1647-1762 Sentence denotes This enzyme also converted GlcA(2-SO4)-[3H]ATalR(6-SO4) to a mixture of GlcA-[3H]ATalR(6-SO4) and [3H]ATalR(6-SO4).
T15 1763-1947 Sentence denotes Digestion of both GlcA(2-SO4)-[3H]AManR(6-SO4) and GlcA(2-SO4)-[3H]ATalR(6-SO4) was inhibited by 35SO2-4 and was arrested at the monosulfated disaccharide stage by 1,4-saccharolactone.
T16 1948-2002 Sentence denotes The glucurono-2-sulfatase exhibited a pH optimum of 4.
T17 2003-2151 Sentence denotes The results indicate that there exists a separate sulfatase for the removal of sulfate substituents from C-2 of GlcA residues in glycosaminoglycans.
T1 0-82 Sentence denotes A sulfatase specific for glucuronic acid 2-sulfate residues in glycosaminoglycans.
T2 83-269 Sentence denotes Although 2-O-sulfated L-iduronic acid (IdoA) residues have been known to occur in heparin, 2-O-sulfated D-glucuronic acid (GlcA) residues have been reported only recently (Bienkowski, M.
T3 270-288 Sentence denotes J., and Conrad, H.
T4 289-301 Sentence denotes E. (1985) J.
T5 302-307 Sentence denotes Biol.
T6 308-313 Sentence denotes Chem.
T7 314-328 Sentence denotes 250, 356-365).
T8 329-566 Sentence denotes Disaccharides prepared by cleavage of heparin and N-deacetylated chondroitin 6-sulfate with nitrous acid were used to demonstrate a new sulfatase that catalyzed the removal of the 2-O-sulfate substituents from GlcA but not IdoA residues.
T9 567-808 Sentence denotes The deamination products were labeled by NaB3H4 reduction to give disaccharides from heparin and chondroitin sulfate which had reducing terminal 2,5-anhydro-D-mannitol ([3H]AManR) and 2,5-anhydro-D-talitol ([3H]ATalR) residues, respectively.
T10 809-945 Sentence denotes IdoA(2-SO4)-[3H]AManR(6-SO4) from heparin and GlcA(2-SO4)-[3H]ATalR(6-SO4) from chondroitin sulfate were purified for use as substrates.
T11 946-1069 Sentence denotes GlcA(2-SO4)-[3H]AManR(6-SO4) was prepared by epimerization of IdoA(2-SO4)-[3H]AManR(6-SO4) with hydrazine at 100 degrees C.
T12 1070-1355 Sentence denotes Lysosomal enzyme preparations from chick embryo chondrocytes and from two normal human fibroblast cell lines catalyzed the removal of the 2-O-SO4 substituent from the uronic acid residues of IdoA(2-SO4)-[3H]AManR(6-SO4), GlcA(2-SO4)-[3H] AManR(6-SO4), and GlcA(2-SO4)-[3H]ATalR(6-SO4).
T13 1356-1646 Sentence denotes In contrast, a lysosomal enzyme preparation from a human fibroblast cell line deficient in idurono-2-sulfatase (Hunter's-syndrome), which had no activity on the IdoA(2-SO4)-[3H]AManR(6-SO4), converted GlcA(2-SO4)-[3H]AManR(6-SO4) to a mixture of GlcA-[3H] AManR(6-SO4) and [3H]AManR(6-SO4).
T14 1647-1762 Sentence denotes This enzyme also converted GlcA(2-SO4)-[3H]ATalR(6-SO4) to a mixture of GlcA-[3H]ATalR(6-SO4) and [3H]ATalR(6-SO4).
T15 1763-1947 Sentence denotes Digestion of both GlcA(2-SO4)-[3H]AManR(6-SO4) and GlcA(2-SO4)-[3H]ATalR(6-SO4) was inhibited by 35SO2-4 and was arrested at the monosulfated disaccharide stage by 1,4-saccharolactone.
T16 1948-2002 Sentence denotes The glucurono-2-sulfatase exhibited a pH optimum of 4.
T17 2003-2151 Sentence denotes The results indicate that there exists a separate sulfatase for the removal of sulfate substituents from C-2 of GlcA residues in glycosaminoglycans.

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-82 Sentence denotes A sulfatase specific for glucuronic acid 2-sulfate residues in glycosaminoglycans.
T2 83-328 Sentence denotes Although 2-O-sulfated L-iduronic acid (IdoA) residues have been known to occur in heparin, 2-O-sulfated D-glucuronic acid (GlcA) residues have been reported only recently (Bienkowski, M. J., and Conrad, H. E. (1985) J. Biol. Chem. 250, 356-365).
T3 329-566 Sentence denotes Disaccharides prepared by cleavage of heparin and N-deacetylated chondroitin 6-sulfate with nitrous acid were used to demonstrate a new sulfatase that catalyzed the removal of the 2-O-sulfate substituents from GlcA but not IdoA residues.
T4 567-808 Sentence denotes The deamination products were labeled by NaB3H4 reduction to give disaccharides from heparin and chondroitin sulfate which had reducing terminal 2,5-anhydro-D-mannitol ([3H]AManR) and 2,5-anhydro-D-talitol ([3H]ATalR) residues, respectively.
T5 809-945 Sentence denotes IdoA(2-SO4)-[3H]AManR(6-SO4) from heparin and GlcA(2-SO4)-[3H]ATalR(6-SO4) from chondroitin sulfate were purified for use as substrates.
T6 946-1355 Sentence denotes GlcA(2-SO4)-[3H]AManR(6-SO4) was prepared by epimerization of IdoA(2-SO4)-[3H]AManR(6-SO4) with hydrazine at 100 degrees C. Lysosomal enzyme preparations from chick embryo chondrocytes and from two normal human fibroblast cell lines catalyzed the removal of the 2-O-SO4 substituent from the uronic acid residues of IdoA(2-SO4)-[3H]AManR(6-SO4), GlcA(2-SO4)-[3H] AManR(6-SO4), and GlcA(2-SO4)-[3H]ATalR(6-SO4).
T7 1356-1646 Sentence denotes In contrast, a lysosomal enzyme preparation from a human fibroblast cell line deficient in idurono-2-sulfatase (Hunter's-syndrome), which had no activity on the IdoA(2-SO4)-[3H]AManR(6-SO4), converted GlcA(2-SO4)-[3H]AManR(6-SO4) to a mixture of GlcA-[3H] AManR(6-SO4) and [3H]AManR(6-SO4).
T8 1647-1762 Sentence denotes This enzyme also converted GlcA(2-SO4)-[3H]ATalR(6-SO4) to a mixture of GlcA-[3H]ATalR(6-SO4) and [3H]ATalR(6-SO4).
T9 1763-1947 Sentence denotes Digestion of both GlcA(2-SO4)-[3H]AManR(6-SO4) and GlcA(2-SO4)-[3H]ATalR(6-SO4) was inhibited by 35SO2-4 and was arrested at the monosulfated disaccharide stage by 1,4-saccharolactone.
T10 1948-2002 Sentence denotes The glucurono-2-sulfatase exhibited a pH optimum of 4.
T11 2003-2151 Sentence denotes The results indicate that there exists a separate sulfatase for the removal of sulfate substituents from C-2 of GlcA residues in glycosaminoglycans.

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue image
T1 394-415 Glycan denotes chondroitin 6-sulfate https://api.glycosmos.org/wurcs2image/latest/png/binary/G34992DF
T2 664-675 Glycan denotes chondroitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT
T3 889-900 Glycan denotes chondroitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT

GlyCosmos15-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 394-415 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes chondroitin 6-sulfate http://www.glycoepitope.jp/epitopes/EP0083
T2 664-675 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes chondroitin http://www.glycoepitope.jp/epitopes/EP0081
T3 889-900 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes chondroitin http://www.glycoepitope.jp/epitopes/EP0081

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 1151-1156 OrganismTaxon denotes human 9606
T2 1407-1412 OrganismTaxon denotes human 9606

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 1111-1117 Body_part denotes embryo http://purl.obolibrary.org/obo/UBERON_0000922
T2 1118-1130 Body_part denotes chondrocytes http://purl.obolibrary.org/obo/CL_0000138
T3 1157-1167 Body_part denotes fibroblast http://purl.obolibrary.org/obo/CL_0000057
T4 1413-1423 Body_part denotes fibroblast http://purl.obolibrary.org/obo/CL_0000057

CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 1118-1130 Cell denotes chondrocytes http://purl.obolibrary.org/obo/CL:0000138
T2 1157-1167 Cell denotes fibroblast http://purl.obolibrary.org/obo/CL:0000057
T3 1413-1423 Cell denotes fibroblast http://purl.obolibrary.org/obo/CL:0000057