PubMed:39073901
Annnotations
CL-cell
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 203-208 | Cell | denotes | sperm | http://purl.obolibrary.org/obo/CL:0000019 |
| T2 | 331-336 | Cell | denotes | sperm | http://purl.obolibrary.org/obo/CL:0000019 |
| T3 | 986-991 | Cell | denotes | sperm | http://purl.obolibrary.org/obo/CL:0000019 |
| T4 | 1076-1081 | Cell | denotes | sperm | http://purl.obolibrary.org/obo/CL:0000019 |
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 358-369 | Disease | denotes | infertility | http://purl.obolibrary.org/obo/MONDO_0005047 |
| T2 | 1127-1142 | Disease | denotes | seminal vesicle | http://purl.obolibrary.org/obo/MONDO_0004767 |
| T3 | 1422-1438 | Disease | denotes | male infertility | http://purl.obolibrary.org/obo/MONDO_0005372 |
| T4 | 1517-1533 | Disease | denotes | male infertility | http://purl.obolibrary.org/obo/MONDO_0005372 |
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 203-208 | Body_part | denotes | sperm | http://purl.obolibrary.org/obo/MAT_0000131|http://purl.obolibrary.org/obo/MAT_0000218 |
| T3 | 331-336 | Body_part | denotes | sperm | http://purl.obolibrary.org/obo/MAT_0000131|http://purl.obolibrary.org/obo/MAT_0000218 |
| T5 | 986-991 | Body_part | denotes | sperm | http://purl.obolibrary.org/obo/MAT_0000131|http://purl.obolibrary.org/obo/MAT_0000218 |
| T7 | 1076-1081 | Body_part | denotes | sperm | http://purl.obolibrary.org/obo/MAT_0000131|http://purl.obolibrary.org/obo/MAT_0000218 |
| T9 | 1127-1142 | Body_part | denotes | seminal vesicle | http://purl.obolibrary.org/obo/MAT_0000171 |
| T10 | 1422-1426 | Body_part | denotes | male | http://purl.obolibrary.org/obo/MAT_0000029 |
| T11 | 1517-1521 | Body_part | denotes | male | http://purl.obolibrary.org/obo/MAT_0000029 |
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 793-800 | Glycan | denotes | lewis x | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00051MO |
| T2 | 802-809 | Glycan | denotes | lewis y | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00052MO |
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 793-800 | Glycan | denotes | lewis x | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00051MO |
| T2 | 802-809 | Glycan | denotes | lewis y | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00052MO |
GlyCosmos-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 793-800 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | lewis x | http://www.glycoepitope.jp/epitopes/EP0011 |
| T2 | 802-809 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | lewis y | http://www.glycoepitope.jp/epitopes/EP0018 |
GlyCosmos15-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 95-112 | Phenotype | denotes | asthenozoospermia | HP:0012207 |
| T2 | 358-369 | Phenotype | denotes | infertility | HP:0000789 |
| T3 | 550-567 | Phenotype | denotes | asthenozoospermia | HP:0012207 |
| T4 | 731-748 | Phenotype | denotes | asthenozoospermia | HP:0012207 |
| T5 | 867-884 | Phenotype | denotes | asthenozoospermia | HP:0012207 |
| T6 | 1280-1297 | Phenotype | denotes | asthenozoospermia | HP:0012207 |
| T7 | 1422-1438 | Phenotype | denotes | male infertility | HP:0003251 |
| T8 | 1517-1533 | Phenotype | denotes | male infertility | HP:0003251 |
GlyCosmos15-CL
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 203-208 | Cell | denotes | sperm | http://purl.obolibrary.org/obo/CL:0000019 |
| T2 | 331-336 | Cell | denotes | sperm | http://purl.obolibrary.org/obo/CL:0000019 |
| T3 | 986-991 | Cell | denotes | sperm | http://purl.obolibrary.org/obo/CL:0000019 |
| T4 | 1076-1081 | Cell | denotes | sperm | http://purl.obolibrary.org/obo/CL:0000019 |
GlyCosmos15-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 77-91 | Body_part | denotes | seminal plasma | http://purl.obolibrary.org/obo/UBERON_0006530 |
| T2 | 149-163 | Body_part | denotes | seminal plasma | http://purl.obolibrary.org/obo/UBERON_0006530 |
| T3 | 203-208 | Body_part | denotes | sperm | http://purl.obolibrary.org/obo/CL_0000019|http://purl.obolibrary.org/obo/UBERON_0001968 |
| T5 | 263-277 | Body_part | denotes | seminal plasma | http://purl.obolibrary.org/obo/UBERON_0006530 |
| T6 | 331-336 | Body_part | denotes | sperm | http://purl.obolibrary.org/obo/CL_0000019|http://purl.obolibrary.org/obo/UBERON_0001968 |
| T8 | 532-546 | Body_part | denotes | seminal plasma | http://purl.obolibrary.org/obo/UBERON_0006530 |
| T9 | 578-583 | Body_part | denotes | scale | http://purl.obolibrary.org/obo/UBERON_0002542 |
| T10 | 642-656 | Body_part | denotes | seminal plasma | http://purl.obolibrary.org/obo/UBERON_0006530 |
| T11 | 957-971 | Body_part | denotes | seminal plasma | http://purl.obolibrary.org/obo/UBERON_0006530 |
| T12 | 986-991 | Body_part | denotes | sperm | http://purl.obolibrary.org/obo/CL_0000019|http://purl.obolibrary.org/obo/UBERON_0001968 |
| T14 | 1076-1081 | Body_part | denotes | sperm | http://purl.obolibrary.org/obo/CL_0000019|http://purl.obolibrary.org/obo/UBERON_0001968 |
| T16 | 1127-1142 | Body_part | denotes | seminal vesicle | http://purl.obolibrary.org/obo/UBERON_0000998 |
| T17 | 1262-1276 | Body_part | denotes | seminal plasma | http://purl.obolibrary.org/obo/UBERON_0006530 |
GlyCosmos15-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 793-800 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | lewis x | http://www.glycoepitope.jp/epitopes/EP0011 |
| T2 | 802-809 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | lewis y | http://www.glycoepitope.jp/epitopes/EP0018 |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-113 | Sentence | denotes | Site-specific N-glycoproteomic analysis reveals up-regulated fucosylation in seminal plasma of asthenozoospermia. |
| T2 | 114-244 | Sentence | denotes | N-linked glycoproteins are rich in seminal plasma, playing essential roles in supporting sperm function and fertilization process. |
| T3 | 245-370 | Sentence | denotes | The alteration of seminal plasma glycans and its correspond glycoproteins may lead to sperm dysfunction and even infertility. |
| T4 | 371-568 | Sentence | denotes | In present study, an integrative analysis of glycoproteomic and proteomic was performed to investigate the changes of site-specific glycans and glycoptoteins in seminal plasma of asthenozoospermia. |
| T5 | 569-749 | Sentence | denotes | By large scale profiling and quantifying 5,018 intact N-glycopeptides in seminal plasma, we identified 92 intact N-glycopeptides from 34 glycoproteins changed in asthenozoospermia. |
| T6 | 750-912 | Sentence | denotes | Especially, fucosylated glycans containing lewis x, lewis y and core fucosylation were significantly up-regulated in asthenozoospermia compared to healthy donors. |
| T7 | 913-1091 | Sentence | denotes | The up-regulation of fucosylated glycans in seminal plasma may interfere sperm surface compositions and regulation of immune response, which subsequently disrupts sperm function. |
| T8 | 1092-1298 | Sentence | denotes | Three differentiated expression of seminal vesicle-specific glycoproteins (fibronectin, seminogelin-2, and glycodelin) were also detected with fucosylation alteration in seminal plasma of asthenozoospermia. |
| T9 | 1299-1534 | Sentence | denotes | The interpretation of the altered site-specific glycan structures provides data for the diagnosis and etiology analysis of male infertility, as well as providing new insights into the potential therapeutic targets for male infertility. |
GlyCosmos15-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 358-369 | Disease | denotes | infertility | MONDO:0005047 |
| T2 | 1422-1438 | Disease | denotes | male infertility | MONDO:0005372 |
| T3 | 1517-1533 | Disease | denotes | male infertility | MONDO:0005372 |
GlyCosmos15-FMA
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 85-91 | Body_part | denotes | plasma | FMA:62970 |
| T2 | 157-163 | Body_part | denotes | plasma | FMA:62970 |
| T3 | 203-208 | Body_part | denotes | sperm | FMA:67338 |
| T4 | 271-277 | Body_part | denotes | plasma | FMA:62970 |
| T5 | 331-336 | Body_part | denotes | sperm | FMA:67338 |
| T6 | 540-546 | Body_part | denotes | plasma | FMA:62970 |
| T7 | 650-656 | Body_part | denotes | plasma | FMA:62970 |
| T8 | 965-971 | Body_part | denotes | plasma | FMA:62970 |
| T9 | 986-991 | Body_part | denotes | sperm | FMA:67338 |
| T10 | 1076-1081 | Body_part | denotes | sperm | FMA:67338 |
| T11 | 1127-1142 | Body_part | denotes | seminal vesicle | FMA:19386 |
| T12 | 1270-1276 | Body_part | denotes | plasma | FMA:62970 |
GlyCosmos15-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 203-208 | Body_part | denotes | sperm | http://purl.obolibrary.org/obo/MAT_0000131|http://purl.obolibrary.org/obo/MAT_0000218 |
| T3 | 331-336 | Body_part | denotes | sperm | http://purl.obolibrary.org/obo/MAT_0000131|http://purl.obolibrary.org/obo/MAT_0000218 |
| T5 | 986-991 | Body_part | denotes | sperm | http://purl.obolibrary.org/obo/MAT_0000131|http://purl.obolibrary.org/obo/MAT_0000218 |
| T7 | 1076-1081 | Body_part | denotes | sperm | http://purl.obolibrary.org/obo/MAT_0000131|http://purl.obolibrary.org/obo/MAT_0000218 |
| T9 | 1127-1142 | Body_part | denotes | seminal vesicle | http://purl.obolibrary.org/obo/MAT_0000171 |
| T10 | 1422-1426 | Body_part | denotes | male | http://purl.obolibrary.org/obo/MAT_0000029 |
| T11 | 1517-1521 | Body_part | denotes | male | http://purl.obolibrary.org/obo/MAT_0000029 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 77-91 | Body_part | denotes | seminal plasma | http://purl.obolibrary.org/obo/UBERON_0006530 |
| T2 | 149-163 | Body_part | denotes | seminal plasma | http://purl.obolibrary.org/obo/UBERON_0006530 |
| T3 | 203-208 | Body_part | denotes | sperm | http://purl.obolibrary.org/obo/CL_0000019|http://purl.obolibrary.org/obo/UBERON_0001968 |
| T5 | 263-277 | Body_part | denotes | seminal plasma | http://purl.obolibrary.org/obo/UBERON_0006530 |
| T6 | 331-336 | Body_part | denotes | sperm | http://purl.obolibrary.org/obo/CL_0000019|http://purl.obolibrary.org/obo/UBERON_0001968 |
| T8 | 532-546 | Body_part | denotes | seminal plasma | http://purl.obolibrary.org/obo/UBERON_0006530 |
| T9 | 578-583 | Body_part | denotes | scale | http://purl.obolibrary.org/obo/UBERON_0002542 |
| T10 | 642-656 | Body_part | denotes | seminal plasma | http://purl.obolibrary.org/obo/UBERON_0006530 |
| T11 | 957-971 | Body_part | denotes | seminal plasma | http://purl.obolibrary.org/obo/UBERON_0006530 |
| T12 | 986-991 | Body_part | denotes | sperm | http://purl.obolibrary.org/obo/CL_0000019|http://purl.obolibrary.org/obo/UBERON_0001968 |
| T14 | 1076-1081 | Body_part | denotes | sperm | http://purl.obolibrary.org/obo/CL_0000019|http://purl.obolibrary.org/obo/UBERON_0001968 |
| T16 | 1127-1142 | Body_part | denotes | seminal vesicle | http://purl.obolibrary.org/obo/UBERON_0000998 |
| T17 | 1262-1276 | Body_part | denotes | seminal plasma | http://purl.obolibrary.org/obo/UBERON_0006530 |
HP-phenotype
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 95-112 | Phenotype | denotes | asthenozoospermia | HP:0012207 |
| T2 | 358-369 | Phenotype | denotes | infertility | HP:0000789 |
| T3 | 550-567 | Phenotype | denotes | asthenozoospermia | HP:0012207 |
| T4 | 731-748 | Phenotype | denotes | asthenozoospermia | HP:0012207 |
| T5 | 867-884 | Phenotype | denotes | asthenozoospermia | HP:0012207 |
| T6 | 1280-1297 | Phenotype | denotes | asthenozoospermia | HP:0012207 |
| T7 | 1422-1438 | Phenotype | denotes | male infertility | HP:0003251 |
| T8 | 1517-1533 | Phenotype | denotes | male infertility | HP:0003251 |