PubMed:38880715
Annnotations
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 1302-1314 | Disease | denotes | inflammation | http://purl.obolibrary.org/obo/MONDO_0021166 |
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 1362-1372 | Body_part | denotes | intestinal | http://purl.obolibrary.org/obo/MAT_0000043 |
| T2 | 1373-1378 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/MAT_0000097 |
| T3 | 1384-1390 | Body_part | denotes | kidney | http://purl.obolibrary.org/obo/MAT_0000119 |
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 27-33 | Glycan | denotes | chitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY |
| T2 | 316-322 | Glycan | denotes | chitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY |
| T3 | 409-415 | Glycan | denotes | chitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY |
| T4 | 466-472 | Glycan | denotes | chitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY |
| T5 | 523-529 | Glycan | denotes | chitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY |
| T6 | 811-817 | Glycan | denotes | chitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY |
| T7 | 906-912 | Glycan | denotes | chitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY |
| T8 | 1000-1006 | Glycan | denotes | chitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY |
| T9 | 1155-1161 | Glycan | denotes | chitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY |
GlyCosmos15-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 1302-1314 | Disease | denotes | inflammation | http://purl.obolibrary.org/obo/MONDO_0021166 |
GlyCosmos15-NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 119-123 | OrganismTaxon | denotes | mice | 10088 |
| T2 | 617-624 | OrganismTaxon | denotes | ammonia | 29189 |
| T3 | 1280-1284 | OrganismTaxon | denotes | mice | 10088 |
GlyCosmos15-CL
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 1139-1149 | Cell | denotes | macrophage | http://purl.obolibrary.org/obo/CL:0000235|http://purl.obolibrary.org/obo/CL:0000394 |
GlyCosmos15-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 1139-1149 | Body_part | denotes | macrophage | http://purl.obolibrary.org/obo/CL_0000235 |
| T2 | 1373-1378 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/UBERON_0002107 |
| T3 | 1384-1390 | Body_part | denotes | kidney | http://purl.obolibrary.org/obo/UBERON_0002113 |
GlyCosmos15-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 1362-1372 | Body_part | denotes | intestinal | http://purl.obolibrary.org/obo/MAT_0000043 |
| T2 | 1373-1378 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/MAT_0000097 |
| T3 | 1384-1390 | Body_part | denotes | kidney | http://purl.obolibrary.org/obo/MAT_0000119 |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-124 | Sentence | denotes | Impact of O-acetylation on chitin oligosaccharides modulating inflammatory responses in LPS-induced RAW264.7 cells and mice. |
| T2 | 125-268 | Sentence | denotes | Chitin oligosaccharides have garnered significant attention due to their biological activities, particularly their immunomodulatory properties. |
| T3 | 269-433 | Sentence | denotes | However, O-acetylation in chemically preparing chitin oligosaccharides seems inevitable and leads to some uncertainty on the bioactivity of chitin oligosaccharides. |
| T4 | 434-731 | Sentence | denotes | In this study, an O-acetyl-free chitin oligosaccharides and three different O-acetylated chitin oligosaccharides with degree of polymerization ranging from 2 to 6 were prepared using ammonia hydrolysis, and their structures and detailed components were further characterized with FTIR, NMR and MS. |
| T5 | 732-874 | Sentence | denotes | Subsequently, the effects of O-acetylation on the immunomodulatory activity of chitin oligosaccharides were investigated in vitro and in vivo. |
| T6 | 875-1150 | Sentence | denotes | The results suggested that the chitin oligosaccharides with O-acetylation exhibited better inflammatory inhibition than pure chitin oligosaccharides, significantly reducing the expression of inflammatory factors, such as IL-6 and iNOS, in the LPS-induced RAW264.7 macrophage. |
| T7 | 1151-1399 | Sentence | denotes | The chitin oligosaccharides with a degree of O-acetylation of 93 % was found to effectively alleviate LPS-induced endotoxemia in mice, including serum inflammation indices reduction and damage repairment of the intestinal liver, and kidney tissues. |
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 27-33 | Glycan | denotes | chitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY |
| T2 | 316-322 | Glycan | denotes | chitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY |
| T3 | 409-415 | Glycan | denotes | chitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY |
| T4 | 466-472 | Glycan | denotes | chitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY |
| T5 | 523-529 | Glycan | denotes | chitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY |
| T6 | 811-817 | Glycan | denotes | chitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY |
| T7 | 906-912 | Glycan | denotes | chitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY |
| T8 | 1000-1006 | Glycan | denotes | chitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY |
| T9 | 1155-1161 | Glycan | denotes | chitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 119-123 | OrganismTaxon | denotes | mice | 10088 |
| T2 | 617-624 | OrganismTaxon | denotes | ammonia | 29189 |
| T3 | 1280-1284 | OrganismTaxon | denotes | mice | 10088 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 1139-1149 | Body_part | denotes | macrophage | http://purl.obolibrary.org/obo/CL_0000235 |
| T2 | 1373-1378 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/UBERON_0002107 |
| T3 | 1384-1390 | Body_part | denotes | kidney | http://purl.obolibrary.org/obo/UBERON_0002113 |
CL-cell
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 1139-1149 | Cell | denotes | macrophage | http://purl.obolibrary.org/obo/CL:0000235|http://purl.obolibrary.org/obo/CL:0000394 |