PubMed:38858439
Annnotations
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 708-711 | Glycan | denotes | GT3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G93899SO |
| T2 | 970-973 | Glycan | denotes | GT3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G93899SO |
| T3 | 1636-1639 | Glycan | denotes | GT3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G93899SO |
| T4 | 2114-2117 | Glycan | denotes | GT3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G93899SO |
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 253-259 | Disease | denotes | injury | http://purl.obolibrary.org/obo/MONDO_0021178 |
| T2 | 518-536 | Disease | denotes | radiation syndrome | http://purl.obolibrary.org/obo/MONDO_0043458 |
| T3 | 1999-2005 | Disease | denotes | injury | http://purl.obolibrary.org/obo/MONDO_0021178 |
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 1342-1366 | Body_part | denotes | gastrointestinal systems | http://purl.obolibrary.org/obo/MAT_0000018 |
| T2 | 1399-1404 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/MAT_0000097 |
| T3 | 1406-1412 | Body_part | denotes | kidney | http://purl.obolibrary.org/obo/MAT_0000119 |
| T4 | 1414-1418 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/MAT_0000135 |
| T5 | 1713-1718 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315 |
| T7 | 1767-1782 | Body_part | denotes | small intestine | http://purl.obolibrary.org/obo/MAT_0000047 |
GlyCosmos-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 708-711 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GT3 | http://www.glycoepitope.jp/epitopes/EP0070 |
| T2 | 970-973 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GT3 | http://www.glycoepitope.jp/epitopes/EP0070 |
| T3 | 1636-1639 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GT3 | http://www.glycoepitope.jp/epitopes/EP0070 |
| T4 | 2114-2117 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GT3 | http://www.glycoepitope.jp/epitopes/EP0070 |
GlyCosmos15-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 253-259 | Disease | denotes | injury | http://purl.obolibrary.org/obo/MONDO_0021178 |
| T2 | 518-536 | Disease | denotes | radiation syndrome | http://purl.obolibrary.org/obo/MONDO_0043458 |
| T3 | 1999-2005 | Disease | denotes | injury | http://purl.obolibrary.org/obo/MONDO_0021178 |
GlyCosmos15-NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 69-77 | OrganismTaxon | denotes | primates | 9443 |
| T2 | 882-890 | OrganismTaxon | denotes | primates | 9443 |
GlyCosmos15-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 988-993 | Body_part | denotes | organ | http://purl.obolibrary.org/obo/UBERON_0000062|http://purl.obolibrary.org/obo/UBERON_0003103 |
| T3 | 1256-1261 | Body_part | denotes | organ | http://purl.obolibrary.org/obo/UBERON_0000062|http://purl.obolibrary.org/obo/UBERON_0003103 |
| T5 | 1342-1366 | Body_part | denotes | gastrointestinal systems | http://purl.obolibrary.org/obo/UBERON_0001007|http://purl.obolibrary.org/obo/UBERON_0005409 |
| T7 | 1399-1404 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/UBERON_0002107 |
| T8 | 1406-1412 | Body_part | denotes | kidney | http://purl.obolibrary.org/obo/UBERON_0002113 |
| T9 | 1414-1418 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
| T10 | 1713-1718 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T11 | 1767-1782 | Body_part | denotes | small intestine | http://purl.obolibrary.org/obo/UBERON_0002108 |
| T12 | 1790-1812 | Body_part | denotes | gastrointestinal tract | http://purl.obolibrary.org/obo/UBERON_0005409 |
| T13 | 2020-2025 | Body_part | denotes | organ | http://purl.obolibrary.org/obo/UBERON_0000062|http://purl.obolibrary.org/obo/UBERON_0003103 |
GlyCosmos15-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 1342-1366 | Body_part | denotes | gastrointestinal systems | http://purl.obolibrary.org/obo/MAT_0000018 |
| T2 | 1399-1404 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/MAT_0000097 |
| T3 | 1406-1412 | Body_part | denotes | kidney | http://purl.obolibrary.org/obo/MAT_0000119 |
| T4 | 1414-1418 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/MAT_0000135 |
| T5 | 1713-1718 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315 |
| T7 | 1767-1782 | Body_part | denotes | small intestine | http://purl.obolibrary.org/obo/MAT_0000047 |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-132 | Sentence | denotes | Pathology of acute sub-lethal or near-lethal irradiation of nonhuman primates prophylaxed with the nutraceutical, gamma tocotrienol. |
| T2 | 133-278 | Sentence | denotes | Exposure to high, marginally lethal doses or higher of ionizing radiation, either intentional or accidental, results in injury to various organs. |
| T3 | 279-431 | Sentence | denotes | Currently, there is only a limited number of safe and effective radiation countermeasures approved by US Food and Drug Administration for such injuries. |
| T4 | 432-669 | Sentence | denotes | These approved agents are effective for only the hematopoietic component of the acute radiation syndrome and must be administered only after the exposure event: currently, there is no FDA-approved agent that can be used prophylactically. |
| T5 | 670-891 | Sentence | denotes | The nutraceutical, gamma-tocotrienol (GT3) has been found to be a promising radioprotector of such exposure-related injuries, especially those of a hematopoietic nature, when tested in either rodents or nonhuman primates. |
| T6 | 892-1169 | Sentence | denotes | We investigated the nature of injuries and the possible protective effects of GT3 within select organ systems/tissues caused by both non-lethal level (4.0 Gy), as well as potentially lethal level (5.8 Gy) of ionizing radiation, delivered as total-body or partial-body exposure. |
| T7 | 1170-1587 | Sentence | denotes | Results indicated that the most severe, dose-dependent injuries occurred within those organ systems with strong self-renewing capacities (e.g., the lymphohematopoietic and gastrointestinal systems), while in other tissues (e.g., liver, kidney, lung) endowed with less self-renewal, the pathologies noted tended to be less pronounced and less dependent on the level of exposure dose or on the applied exposure regimen. |
| T8 | 1588-1813 | Sentence | denotes | The prophylactic use of the test nutraceutical, GT3, appeared to limit the extent of irradiation-associated pathology within blood forming tissues and, to some extent, within the small intestine of the gastrointestinal tract. |
| T9 | 1814-2134 | Sentence | denotes | No distinct, global pattern of bodily protection was noted with the agent's use, although a hint of a possible radioprotective benefit was suggested not only by a lessening of apparent injury within select organ systems, but also by way of noting the lack of early onset of moribundity within select GT3-treated animals. |
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 708-711 | Glycan | denotes | GT3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G93899SO |
| T2 | 970-973 | Glycan | denotes | GT3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G93899SO |
| T3 | 1636-1639 | Glycan | denotes | GT3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G93899SO |
| T4 | 2114-2117 | Glycan | denotes | GT3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G93899SO |
GlyCosmos15-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 708-711 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GT3 | http://www.glycoepitope.jp/epitopes/EP0070 |
| T2 | 970-973 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GT3 | http://www.glycoepitope.jp/epitopes/EP0070 |
| T3 | 1636-1639 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GT3 | http://www.glycoepitope.jp/epitopes/EP0070 |
| T4 | 2114-2117 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GT3 | http://www.glycoepitope.jp/epitopes/EP0070 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 69-77 | OrganismTaxon | denotes | primates | 9443 |
| T2 | 882-890 | OrganismTaxon | denotes | primates | 9443 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 988-993 | Body_part | denotes | organ | http://purl.obolibrary.org/obo/UBERON_0000062|http://purl.obolibrary.org/obo/UBERON_0003103 |
| T3 | 1256-1261 | Body_part | denotes | organ | http://purl.obolibrary.org/obo/UBERON_0000062|http://purl.obolibrary.org/obo/UBERON_0003103 |
| T5 | 1342-1366 | Body_part | denotes | gastrointestinal systems | http://purl.obolibrary.org/obo/UBERON_0001007|http://purl.obolibrary.org/obo/UBERON_0005409 |
| T7 | 1399-1404 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/UBERON_0002107 |
| T8 | 1406-1412 | Body_part | denotes | kidney | http://purl.obolibrary.org/obo/UBERON_0002113 |
| T9 | 1414-1418 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
| T10 | 1713-1718 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T11 | 1767-1782 | Body_part | denotes | small intestine | http://purl.obolibrary.org/obo/UBERON_0002108 |
| T12 | 1790-1812 | Body_part | denotes | gastrointestinal tract | http://purl.obolibrary.org/obo/UBERON_0005409 |
| T13 | 2020-2025 | Body_part | denotes | organ | http://purl.obolibrary.org/obo/UBERON_0000062|http://purl.obolibrary.org/obo/UBERON_0003103 |