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PubMed:38509156 JSONTXT

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mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 257-263 Disease denotes asthma http://purl.obolibrary.org/obo/MONDO_0004979
T2 265-282 Disease denotes allergic rhinitis http://purl.obolibrary.org/obo/MONDO_0011786
T3 288-300 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T4 519-536 Disease denotes fungal infections http://purl.obolibrary.org/obo/MONDO_0002041
T5 1069-1086 Disease denotes allergic response http://purl.obolibrary.org/obo/MONDO_0005271
T6 1821-1827 Disease denotes asthma http://purl.obolibrary.org/obo/MONDO_0004979
T7 2105-2115 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550

HP-phenotype

Id Subject Object Predicate Lexical cue hp_id
T1 257-263 Phenotype denotes asthma HP:0002099
T2 265-282 Phenotype denotes allergic rhinitis HP:0003193
T3 1821-1827 Phenotype denotes asthma HP:0002099

Glycan-GlyCosmos

Id Subject Object Predicate Lexical cue image
T1 1424-1430 Glycan denotes chitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY

GlyCosmos15-HP

Id Subject Object Predicate Lexical cue hp_id
T1 257-263 Phenotype denotes asthma HP:0002099
T2 265-282 Phenotype denotes allergic rhinitis HP:0003193
T3 1821-1827 Phenotype denotes asthma HP:0002099

GlyCosmos15-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 257-263 Disease denotes asthma http://purl.obolibrary.org/obo/MONDO_0004979
T2 265-282 Disease denotes allergic rhinitis http://purl.obolibrary.org/obo/MONDO_0011786
T3 288-300 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T4 519-536 Disease denotes fungal infections http://purl.obolibrary.org/obo/MONDO_0002041
T5 1069-1086 Disease denotes allergic response http://purl.obolibrary.org/obo/MONDO_0005271
T6 1821-1827 Disease denotes asthma http://purl.obolibrary.org/obo/MONDO_0004979
T7 2105-2115 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550

GlyCosmos15-NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 100-120 OrganismTaxon denotes Alternaria alternata 5599
T2 190-210 OrganismTaxon denotes Alternaria alternata 5599

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-151 Sentence denotes In silico approaches for the identification of potential allergens among hypothetical proteins from Alternaria alternata and its functional annotation.
T2 152-301 Sentence denotes Direct exposure to the fungal species Alternaria alternata is a major risk factor for the development of asthma, allergic rhinitis, and inflammation.
T3 302-433 Sentence denotes As of November 23rd 2020, the NCBI protein database showed 11,227 proteins from A. alternata genome as hypothetical proteins (HPs).
T4 434-537 Sentence denotes Allergens are the main causative of several life-threatening diseases, especially in fungal infections.
T5 538-796 Sentence denotes Therefore, the main aim of the study is to identify the potentially allergenic inducible proteins from the HPs in A. alternata and their associated functional assignment for the complete understanding of the complex biological systems at the molecular level.
T6 797-940 Sentence denotes AlgPred and Structural Database of Allergenic Proteins (SDAP) were used for the prediction of potential allergens from the HPs of A. alternata.
T7 941-1102 Sentence denotes While analyzing the proteome data, 29 potential allergens were predicted by AlgPred and further screening in SDAP confirmed the allergic response of 10 proteins.
T8 1103-1377 Sentence denotes Extensive bioinformatics tools including protein family classification, sequence-function relationship, protein motif discovery, pathway interactions, and intrinsic features from the amino acid sequence were used to successfully predict the probable functions of the 10 HPs.
T9 1378-1511 Sentence denotes The functions of the HPs are characterized as chitin-binding, ribosomal protein P1, thaumatin, glycosyl hydrolase, and NOB1 proteins.
T10 1512-1665 Sentence denotes The subcellular localization and signal peptide prediction of these 10 proteins has further provided additional information on localization and function.
T11 1666-1847 Sentence denotes The allergens prediction and functional annotation of the 10 proteins may facilitate a better understanding of the allergenic mechanism of A. alternata in asthma and other diseases.
T12 1848-2008 Sentence denotes The functional domain level insights and predicted structural features of the allergenic proteins help to understand the pathogenesis and host immune tolerance.
T13 2009-2116 Sentence denotes The outcomes of the study would aid in the development of specific drugs to combat A. alternata infections.

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue image
T1 1424-1430 Glycan denotes chitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 100-120 OrganismTaxon denotes Alternaria alternata 5599
T2 190-210 OrganismTaxon denotes Alternaria alternata 5599