PubMed:38336175
Annnotations
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 757-760 | Disease | denotes | MS2 | http://purl.obolibrary.org/obo/MONDO_0012956 |
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 585-593 | Glycan | denotes | O-GlcNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G49108TO |
| T2 | 816-824 | Glycan | denotes | O-GlcNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G49108TO |
| T3 | 1152-1160 | Glycan | denotes | O-GlcNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G49108TO |
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 585-593 | Glycan | denotes | O-GlcNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G49108TO |
| T2 | 816-824 | Glycan | denotes | O-GlcNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G49108TO |
| T3 | 1152-1160 | Glycan | denotes | O-GlcNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G49108TO |
GlyCosmos-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 585-593 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | O-GlcNAc | http://www.glycoepitope.jp/epitopes/EP0004 |
| T2 | 816-824 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | O-GlcNAc | http://www.glycoepitope.jp/epitopes/EP0004 |
| T3 | 1152-1160 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | O-GlcNAc | http://www.glycoepitope.jp/epitopes/EP0004 |
GlyCosmos15-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 69-87 | Body_part | denotes | Cellular Processes | http://purl.obolibrary.org/obo/GO_0042995 |
| T2 | 1222-1240 | Body_part | denotes | cellular processes | http://purl.obolibrary.org/obo/GO_0042995 |
GlyCosmos15-Taxon
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 91-102 | Organism | denotes | Arabidopsis | 3701 |
| T2 | 707-718 | Organism | denotes | Arabidopsis | 3701 |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-103 | Sentence | denotes | SECRET AGENT O-GlcNAcylates Hundreds of Proteins Involved in Diverse Cellular Processes in Arabidopsis. |
| T2 | 104-261 | Sentence | denotes | O-GlcNAcylation is a critical post-translational modification of proteins observed in both plants and animals and plays a key role in growth and development. |
| T3 | 262-402 | Sentence | denotes | While considerable knowledge exists about over 3000 substrates in animals, our understanding of this modification in plants remains limited. |
| T4 | 403-542 | Sentence | denotes | Unlike animals, plants possess two putative homologs: SECRET AGENT (SEC) and SPINDLY, with SPINDLY also exhibiting O-fucosylation activity. |
| T5 | 543-768 | Sentence | denotes | To investigate the role of SEC as a major O-GlcNAc transferase in plants, we utilized lectin-weak affinity chromatography enrichment and stable isotope labeling in Arabidopsis labeling, quantifying at both MS1 and MS2 levels. |
| T6 | 769-916 | Sentence | denotes | Our findings reveal a significant reduction in O-GlcNAc levels in the sec mutant, indicating the critical role of SEC in mediating O-GlcNAcylation. |
| T7 | 917-1196 | Sentence | denotes | Through a comprehensive approach, combining higher-energy collision dissociation and electron-transfer high-energy collision dissociation fragmentation with substantial fractionations, we expanded our GlcNAc profiling, identifying 436 O-GlcNAc targets, including 227 new targets. |
| T8 | 1197-1299 | Sentence | denotes | The targets span diverse cellular processes, suggesting broad regulatory functions of O-GlcNAcylation. |
| T9 | 1300-1402 | Sentence | denotes | The expanded targets also enabled exploration of crosstalk between O-GlcNAcylation and O-fucosylation. |
| T10 | 1403-1507 | Sentence | denotes | We also examined electron-transfer high-energy collision dissociation fragmentation for site assignment. |
| T11 | 1508-1621 | Sentence | denotes | This report advances our understanding of O-GlcNAcylation in plants, facilitating further research in this field. |
GlyCosmos15-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 585-593 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | O-GlcNAc | http://www.glycoepitope.jp/epitopes/EP0004 |
| T2 | 816-824 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | O-GlcNAc | http://www.glycoepitope.jp/epitopes/EP0004 |
| T3 | 1152-1160 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | O-GlcNAc | http://www.glycoepitope.jp/epitopes/EP0004 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 91-102 | OrganismTaxon | denotes | Arabidopsis | 3701 |
| T2 | 707-718 | OrganismTaxon | denotes | Arabidopsis | 3701 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 69-87 | Body_part | denotes | Cellular Processes | http://purl.obolibrary.org/obo/GO_0042995 |
| T2 | 1222-1240 | Body_part | denotes | cellular processes | http://purl.obolibrary.org/obo/GO_0042995 |