| Id |
Subject |
Object |
Predicate |
Lexical cue |
| TextSentencer_T1 |
0-83 |
Sentence |
denotes |
Evidence for structural changes in dermatan sulfate and hyaluronic acid with aging. |
| TextSentencer_T2 |
84-238 |
Sentence |
denotes |
Three dermatan sulfates (DS18, DS28, and DS35) were isolated from women's skin of ages 19 +/- 2.5, 35 +/- 3.5, 47 +/- 1.7, 60 +/- 0.8, and 75 +/- 5 years. |
| TextSentencer_T3 |
239-299 |
Sentence |
denotes |
They sequentially precipitated with 18, 28, and 35% ethanol. |
| TextSentencer_T4 |
300-326 |
Sentence |
denotes |
Their sulfate content was: |
| TextSentencer_T5 |
327-524 |
Sentence |
denotes |
23.5, 25.3, and 29.0% (w/w) for DS18 at ages 19-35, 47, and 60 years, respectively; 29.0, 24.0, and 18.8% for DS28; and 18.0, 20.0, and 20.6% for DS35 at ages 19-47, 60, and 75 years, respectively. |
| TextSentencer_T6 |
525-660 |
Sentence |
denotes |
Both DS18 and DS28 decreased, respectively, from 0.030% (of wet-skin weight) to traces at age 75, and from 0.020 to 0.010% at 60 years. |
| TextSentencer_T7 |
661-705 |
Sentence |
denotes |
At age 75, DS28 apparently increased by 30%. |
| TextSentencer_T8 |
706-763 |
Sentence |
denotes |
The DS35 values (traces-0.006%) had no age-related trend. |
| TextSentencer_T9 |
764-924 |
Sentence |
denotes |
Hyaluronic acid (HA) precipitated with 45% ethanol, was 0.030% of skin-weight at ages 19-47, and decreased to 0.015 and 0.007% at 60 and 75 years, respectively. |
| TextSentencer_T10 |
925-975 |
Sentence |
denotes |
Its electrophoretic mobility was slower at age 47. |
| TextSentencer_T11 |
976-1107 |
Sentence |
denotes |
In the oldest group, i.r. spectra of HA and DS35 displayed no bands at 1650-1600, 1380, and 1320 cm-1, and a new band at 1560 cm-1. |
| TextSentencer_T12 |
1108-1248 |
Sentence |
denotes |
Moreover, ninhydrin-positive material of HA and DS35 increased by 75 and 95%, respectively, and the reducing GlcNAc content of HA decreased. |
| TextSentencer_T13 |
1249-1400 |
Sentence |
denotes |
These data showed three chemically different dermatan sulfates (two of which were preponderant) and N-deacetylation of HA and DS35 of the oldest group. |
| TextSentencer_T14 |
1401-1529 |
Sentence |
denotes |
After age 47, total DS and HA considerably decreased, DS18 and DS35 were oversulfated, and DS28 became undersulfated with aging. |
| T1 |
0-83 |
Sentence |
denotes |
Evidence for structural changes in dermatan sulfate and hyaluronic acid with aging. |
| T2 |
84-238 |
Sentence |
denotes |
Three dermatan sulfates (DS18, DS28, and DS35) were isolated from women's skin of ages 19 +/- 2.5, 35 +/- 3.5, 47 +/- 1.7, 60 +/- 0.8, and 75 +/- 5 years. |
| T3 |
239-299 |
Sentence |
denotes |
They sequentially precipitated with 18, 28, and 35% ethanol. |
| T4 |
300-326 |
Sentence |
denotes |
Their sulfate content was: |
| T5 |
327-524 |
Sentence |
denotes |
23.5, 25.3, and 29.0% (w/w) for DS18 at ages 19-35, 47, and 60 years, respectively; 29.0, 24.0, and 18.8% for DS28; and 18.0, 20.0, and 20.6% for DS35 at ages 19-47, 60, and 75 years, respectively. |
| T6 |
525-660 |
Sentence |
denotes |
Both DS18 and DS28 decreased, respectively, from 0.030% (of wet-skin weight) to traces at age 75, and from 0.020 to 0.010% at 60 years. |
| T7 |
661-705 |
Sentence |
denotes |
At age 75, DS28 apparently increased by 30%. |
| T8 |
706-763 |
Sentence |
denotes |
The DS35 values (traces-0.006%) had no age-related trend. |
| T9 |
764-924 |
Sentence |
denotes |
Hyaluronic acid (HA) precipitated with 45% ethanol, was 0.030% of skin-weight at ages 19-47, and decreased to 0.015 and 0.007% at 60 and 75 years, respectively. |
| T10 |
925-975 |
Sentence |
denotes |
Its electrophoretic mobility was slower at age 47. |
| T11 |
976-1107 |
Sentence |
denotes |
In the oldest group, i.r. spectra of HA and DS35 displayed no bands at 1650-1600, 1380, and 1320 cm-1, and a new band at 1560 cm-1. |
| T12 |
1108-1248 |
Sentence |
denotes |
Moreover, ninhydrin-positive material of HA and DS35 increased by 75 and 95%, respectively, and the reducing GlcNAc content of HA decreased. |
| T13 |
1249-1400 |
Sentence |
denotes |
These data showed three chemically different dermatan sulfates (two of which were preponderant) and N-deacetylation of HA and DS35 of the oldest group. |
| T14 |
1401-1529 |
Sentence |
denotes |
After age 47, total DS and HA considerably decreased, DS18 and DS35 were oversulfated, and DS28 became undersulfated with aging. |