PubMed:37697028
Annnotations
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 1167-1174 | Glycan | denotes | lactose | https://api.glycosmos.org/wurcs2image/latest/png/binary/G15541SE |
HP-phenotype
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 54-63 | Phenotype | denotes | neuralgia | HP:0033345 |
| T2 | 166-175 | Phenotype | denotes | neuralgia | HP:0033345 |
| T3 | 300-304 | Phenotype | denotes | pain | HP:0012531 |
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 40-63 | Disease | denotes | post-herpetic neuralgia | http://purl.obolibrary.org/obo/MONDO_0005609|http://purl.obolibrary.org/obo/MONDO_0041052 |
| T3 | 75-84 | Disease | denotes | varicella | http://purl.obolibrary.org/obo/MONDO_0005700 |
| T4 | 85-91 | Disease | denotes | zoster | http://purl.obolibrary.org/obo/MONDO_0005609 |
| T5 | 152-175 | Disease | denotes | post-herpetic neuralgia | http://purl.obolibrary.org/obo/MONDO_0005609|http://purl.obolibrary.org/obo/MONDO_0041052 |
| T7 | 177-180 | Disease | denotes | PHN | http://purl.obolibrary.org/obo/MONDO_0005609 |
| T8 | 193-206 | Disease | denotes | herpes zoster | http://purl.obolibrary.org/obo/MONDO_0005609 |
| T9 | 208-210 | Disease | denotes | HZ | http://purl.obolibrary.org/obo/MONDO_0005609 |
| T10 | 323-326 | Disease | denotes | PHN | http://purl.obolibrary.org/obo/MONDO_0005609 |
| T11 | 664-667 | Disease | denotes | PHN | http://purl.obolibrary.org/obo/MONDO_0005609 |
| T12 | 861-864 | Disease | denotes | PHN | http://purl.obolibrary.org/obo/MONDO_0005609 |
| T13 | 1060-1063 | Disease | denotes | PHN | http://purl.obolibrary.org/obo/MONDO_0005609 |
| T14 | 1257-1260 | Disease | denotes | PHN | http://purl.obolibrary.org/obo/MONDO_0005609 |
| T15 | 1412-1415 | Disease | denotes | PHN | http://purl.obolibrary.org/obo/MONDO_0005609 |
| T16 | 1483-1486 | Disease | denotes | PHN | http://purl.obolibrary.org/obo/MONDO_0005609 |
| T17 | 1498-1500 | Disease | denotes | HZ | http://purl.obolibrary.org/obo/MONDO_0005609 |
GlyCosmos15-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 54-63 | Phenotype | denotes | neuralgia | HP:0033345 |
| T2 | 166-175 | Phenotype | denotes | neuralgia | HP:0033345 |
| T3 | 300-304 | Phenotype | denotes | pain | HP:0012531 |
GlyCosmos15-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 40-63 | Disease | denotes | post-herpetic neuralgia | http://purl.obolibrary.org/obo/MONDO_0005609|http://purl.obolibrary.org/obo/MONDO_0041052 |
| T3 | 75-84 | Disease | denotes | varicella | http://purl.obolibrary.org/obo/MONDO_0005700 |
| T4 | 85-91 | Disease | denotes | zoster | http://purl.obolibrary.org/obo/MONDO_0005609 |
| T5 | 152-175 | Disease | denotes | post-herpetic neuralgia | http://purl.obolibrary.org/obo/MONDO_0005609|http://purl.obolibrary.org/obo/MONDO_0041052 |
| T7 | 177-180 | Disease | denotes | PHN | http://purl.obolibrary.org/obo/MONDO_0005609 |
| T8 | 193-206 | Disease | denotes | herpes zoster | http://purl.obolibrary.org/obo/MONDO_0005609 |
| T9 | 208-210 | Disease | denotes | HZ | http://purl.obolibrary.org/obo/MONDO_0005609 |
| T10 | 323-326 | Disease | denotes | PHN | http://purl.obolibrary.org/obo/MONDO_0005609 |
| T11 | 664-667 | Disease | denotes | PHN | http://purl.obolibrary.org/obo/MONDO_0005609 |
| T12 | 861-864 | Disease | denotes | PHN | http://purl.obolibrary.org/obo/MONDO_0005609 |
| T13 | 1060-1063 | Disease | denotes | PHN | http://purl.obolibrary.org/obo/MONDO_0005609 |
| T14 | 1257-1260 | Disease | denotes | PHN | http://purl.obolibrary.org/obo/MONDO_0005609 |
| T15 | 1412-1415 | Disease | denotes | PHN | http://purl.obolibrary.org/obo/MONDO_0005609 |
| T16 | 1483-1486 | Disease | denotes | PHN | http://purl.obolibrary.org/obo/MONDO_0005609 |
| T17 | 1498-1500 | Disease | denotes | HZ | http://purl.obolibrary.org/obo/MONDO_0005609 |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-92 | Sentence | denotes | Metabolomics profiling in predicting of post-herpetic neuralgia induced by varicella zoster. |
| T2 | 93-212 | Sentence | denotes | To explore potential metabolomics biomarkers in predicting post-herpetic neuralgia (PHN) induced by herpes zoster (HZ). |
| T3 | 213-333 | Sentence | denotes | A total of 90 eligible patients were prospectively enrolled and assigned into an acute pain (ACP) group and a PHN group. |
| T4 | 334-486 | Sentence | denotes | Serum samples were collected before clinical intervention to perform metabolomics profiling analyses using gas chromatography mass spectrometry (GC-MS). |
| T5 | 487-578 | Sentence | denotes | Key metabolites were identified using partial least squares discriminant analysis (PLS-DA). |
| T6 | 579-677 | Sentence | denotes | A binary logistic regression was used to build a combined biomarker model to predict PHN from ACP. |
| T7 | 678-794 | Sentence | denotes | The discriminating efficiency of the combined biomarker model was investigated and validated by internal validation. |
| T8 | 795-865 | Sentence | denotes | Six metabolites were identified as the key metabolites related to PHN. |
| T9 | 866-1070 | Sentence | denotes | All these metabolites (N-Acetyl-5-hydroxytryptaMine, glucose, dehydroascorbic acid, isopropyl-beta-D-thiogalactopyranoside, 1,5-anhydro-D-sorbitol, and glutamic acid) were found elevated in the PHN group. |
| T10 | 1071-1261 | Sentence | denotes | Pathway analyses showed that glucose-alanine cycle, tryptophan metabolism, tyrosine metabolism, lactose degradation, malate-aspartate shuttle were top five metabolic pathways evolved in PHN. |
| T11 | 1262-1416 | Sentence | denotes | The AUC was 0.85 (95% CI 0.76-0.93) for the combined biomarker model, and was 0.91 (95% CI 0.84-1.00) for the internal validation data set to predict PHN. |
| T12 | 1417-1501 | Sentence | denotes | Metabolomics analyses of key metabolites could be used to predict PHN induced by HZ. |
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 1167-1174 | Glycan | denotes | lactose | https://api.glycosmos.org/wurcs2image/latest/png/binary/G15541SE |