PubMed:37349387
Annnotations
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 753-765 | Disease | denotes | yellow fever | http://purl.obolibrary.org/obo/MONDO_0020502 |
HP-phenotype
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 760-765 | Phenotype | denotes | fever | HP:0001945 |
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 437-444 | Body_part | denotes | cuticle | http://purl.obolibrary.org/obo/MAT_0000150 |
| T2 | 581-588 | Body_part | denotes | Cuticle | http://purl.obolibrary.org/obo/MAT_0000150 |
| T3 | 991-998 | Body_part | denotes | cuticle | http://purl.obolibrary.org/obo/MAT_0000150 |
| T4 | 1223-1230 | Body_part | denotes | cuticle | http://purl.obolibrary.org/obo/MAT_0000150 |
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 475-481 | Glycan | denotes | chitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY |
GlyCosmos15-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 430-444 | Body_part | denotes | insect cuticle | http://purl.obolibrary.org/obo/UBERON_0001001 |
| T2 | 581-588 | Body_part | denotes | Cuticle | http://purl.obolibrary.org/obo/UBERON_0001001|http://purl.obolibrary.org/obo/UBERON_0001002|http://purl.obolibrary.org/obo/UBERON_0004882 |
| T5 | 991-998 | Body_part | denotes | cuticle | http://purl.obolibrary.org/obo/UBERON_0001001|http://purl.obolibrary.org/obo/UBERON_0001002|http://purl.obolibrary.org/obo/UBERON_0004882 |
| T8 | 1223-1230 | Body_part | denotes | cuticle | http://purl.obolibrary.org/obo/UBERON_0001001|http://purl.obolibrary.org/obo/UBERON_0001002|http://purl.obolibrary.org/obo/UBERON_0004882 |
GlyCosmos15-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 760-765 | Phenotype | denotes | fever | HP:0001945 |
GlyCosmos15-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 753-765 | Disease | denotes | yellow fever | http://purl.obolibrary.org/obo/MONDO_0020502 |
GlyCosmos15-NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 45-58 | OrganismTaxon | denotes | Aedes aegypti | 7159 |
| T2 | 776-789 | OrganismTaxon | denotes | Aedes aegypti | 7159 |
GlyCosmos15-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 437-444 | Body_part | denotes | cuticle | http://purl.obolibrary.org/obo/MAT_0000150 |
| T2 | 581-588 | Body_part | denotes | Cuticle | http://purl.obolibrary.org/obo/MAT_0000150 |
| T3 | 991-998 | Body_part | denotes | cuticle | http://purl.obolibrary.org/obo/MAT_0000150 |
| T4 | 1223-1230 | Body_part | denotes | cuticle | http://purl.obolibrary.org/obo/MAT_0000150 |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-59 | Sentence | denotes | Cuticular profiling of insecticide resistant Aedes aegypti. |
| T2 | 60-151 | Sentence | denotes | Insecticides have made great strides in reducing the global burden of vector-borne disease. |
| T3 | 152-280 | Sentence | denotes | Nonetheless, serious public health concerns remain because insecticide-resistant vector populations continue to spread globally. |
| T4 | 281-377 | Sentence | denotes | To circumvent insecticide resistance, it is essential to understand all contributing mechanisms. |
| T5 | 378-580 | Sentence | denotes | Contact-based insecticides are absorbed through the insect cuticle, which is comprised mainly of chitin polysaccharides, cuticular proteins, hydrocarbons, and phenolic biopolymers sclerotin and melanin. |
| T6 | 581-707 | Sentence | denotes | Cuticle interface alterations can slow or prevent insecticide penetration in a phenomenon referred to as cuticular resistance. |
| T7 | 708-802 | Sentence | denotes | Cuticular resistance characterization of the yellow fever mosquito, Aedes aegypti, is lacking. |
| T8 | 803-1103 | Sentence | denotes | In the current study, we utilized solid-state nuclear magnetic resonance spectroscopy, gas chromatography/mass spectrometry, and transmission electron microscopy to gain insights into the cuticle composition of congenic cytochrome P450 monooxygenase insecticide resistant and susceptible Ae. aegypti. |
| T9 | 1104-1197 | Sentence | denotes | No differences in cuticular hydrocarbon content or phenolic biopolymer deposition were found. |
| T10 | 1198-1344 | Sentence | denotes | In contrast, we observed cuticle thickness of insecticide resistant Ae. aegypti increased over time and exhibited higher polysaccharide abundance. |
| T11 | 1345-1557 | Sentence | denotes | Moreover, we found these local cuticular changes correlated with global metabolic differences in the whole mosquito, suggesting the existence of novel cuticular resistance mechanisms in this major disease vector. |
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 475-481 | Glycan | denotes | chitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 45-58 | OrganismTaxon | denotes | Aedes aegypti | 7159 |
| T2 | 776-789 | OrganismTaxon | denotes | Aedes aegypti | 7159 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 430-444 | Body_part | denotes | insect cuticle | http://purl.obolibrary.org/obo/UBERON_0001001 |
| T2 | 581-588 | Body_part | denotes | Cuticle | http://purl.obolibrary.org/obo/UBERON_0001001|http://purl.obolibrary.org/obo/UBERON_0001002|http://purl.obolibrary.org/obo/UBERON_0004882 |
| T5 | 991-998 | Body_part | denotes | cuticle | http://purl.obolibrary.org/obo/UBERON_0001001|http://purl.obolibrary.org/obo/UBERON_0001002|http://purl.obolibrary.org/obo/UBERON_0004882 |
| T8 | 1223-1230 | Body_part | denotes | cuticle | http://purl.obolibrary.org/obo/UBERON_0001001|http://purl.obolibrary.org/obo/UBERON_0001002|http://purl.obolibrary.org/obo/UBERON_0004882 |