PubMed:37150898
Annnotations
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 138-144 | Body_part | denotes | Saliva | http://purl.obolibrary.org/obo/MAT_0000444 |
| T2 | 339-345 | Body_part | denotes | saliva | http://purl.obolibrary.org/obo/MAT_0000444 |
| T3 | 2181-2187 | Body_part | denotes | saliva | http://purl.obolibrary.org/obo/MAT_0000444 |
GlyCosmos15-Species
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| 2 | 80-90 | Species | denotes | SARS-CoV-2 | 2697049 |
| 26 | 198-208 | Species | denotes | SARS-CoV-2 | 2697049 |
| 27 | 269-316 | Species | denotes | severe acute respiratory syndrome coronavirus 2 | 2697049 |
| 28 | 318-328 | Species | denotes | SARS-CoV-2 | 2697049 |
| 35 | 832-842 | Species | denotes | SARS-CoV-2 | 2697049 |
| 36 | 900-910 | Species | denotes | SARS-CoV-2 | 2697049 |
| 38 | 956-966 | Species | denotes | SARS-CoV-2 | 2697049 |
| 44 | 1602-1612 | Species | denotes | SARS-CoV-2 | 2697049 |
| 45 | 1636-1646 | Species | denotes | SARS-CoV-2 | 2697049 |
| 46 | 1727-1737 | Species | denotes | SARS-CoV-2 | 2697049 |
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 433-440 | Glycan | denotes | maltose | https://api.glycosmos.org/wurcs2image/latest/png/binary/G44653LT |
| T2 | 487-494 | Glycan | denotes | maltose | https://api.glycosmos.org/wurcs2image/latest/png/binary/G44653LT |
HP-phenotype
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 97-100 | Phenotype | denotes | RBD | HP:5200291 |
| T2 | 240-243 | Phenotype | denotes | RBD | HP:5200291 |
| T3 | 769-772 | Phenotype | denotes | RBD | HP:5200291 |
| T4 | 849-852 | Phenotype | denotes | RBD | HP:5200291 |
| T5 | 1619-1622 | Phenotype | denotes | RBD | HP:5200291 |
| T6 | 1744-1747 | Phenotype | denotes | RBD | HP:5200291 |
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 80-90 | Disease | denotes | SARS-CoV-2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T2 | 118-128 | Disease | denotes | SARS-CoV-2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T3 | 198-208 | Disease | denotes | SARS-CoV-2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T4 | 269-316 | Disease | denotes | severe acute respiratory syndrome coronavirus 2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T5 | 318-328 | Disease | denotes | SARS-CoV-2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T6 | 832-842 | Disease | denotes | SARS-CoV-2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T7 | 900-910 | Disease | denotes | SARS-CoV-2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T8 | 956-966 | Disease | denotes | SARS-CoV-2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T9 | 1602-1612 | Disease | denotes | SARS-CoV-2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T10 | 1636-1646 | Disease | denotes | SARS-CoV-2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T11 | 1727-1737 | Disease | denotes | SARS-CoV-2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T12 | 1836-1844 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T13 | 1923-1933 | Disease | denotes | SARS-CoV-2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 433-440 | Glycan | denotes | maltose | https://api.glycosmos.org/wurcs2image/latest/png/binary/G44653LT |
| T2 | 487-494 | Glycan | denotes | maltose | https://api.glycosmos.org/wurcs2image/latest/png/binary/G44653LT |
GlyCosmos15-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 138-144 | Body_part | denotes | Saliva | http://purl.obolibrary.org/obo/UBERON_0001836 |
| T2 | 339-345 | Body_part | denotes | saliva | http://purl.obolibrary.org/obo/UBERON_0001836 |
| T3 | 791-805 | Body_part | denotes | microparticles | http://purl.obolibrary.org/obo/GO_1903561 |
| T4 | 1073-1087 | Body_part | denotes | microparticles | http://purl.obolibrary.org/obo/GO_1903561 |
| T5 | 1233-1247 | Body_part | denotes | microparticles | http://purl.obolibrary.org/obo/GO_1903561 |
| T6 | 2181-2187 | Body_part | denotes | saliva | http://purl.obolibrary.org/obo/UBERON_0001836 |
GlyCosmos15-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 80-90 | Disease | denotes | SARS-CoV-2 | MONDO:0100096 |
| T2 | 118-128 | Disease | denotes | SARS-CoV-2 | MONDO:0100096 |
| T3 | 198-208 | Disease | denotes | SARS-CoV-2 | MONDO:0100096 |
| T4 | 269-316 | Disease | denotes | severe acute respiratory syndrome coronavirus 2 | MONDO:0100096 |
| T5 | 318-328 | Disease | denotes | SARS-CoV-2 | MONDO:0100096 |
| T6 | 832-842 | Disease | denotes | SARS-CoV-2 | MONDO:0100096 |
| T7 | 900-910 | Disease | denotes | SARS-CoV-2 | MONDO:0100096 |
| T8 | 956-966 | Disease | denotes | SARS-CoV-2 | MONDO:0100096 |
| T9 | 1602-1612 | Disease | denotes | SARS-CoV-2 | MONDO:0100096 |
| T10 | 1636-1646 | Disease | denotes | SARS-CoV-2 | MONDO:0100096 |
| T11 | 1727-1737 | Disease | denotes | SARS-CoV-2 | MONDO:0100096 |
| T12 | 1836-1844 | Disease | denotes | COVID-19 | MONDO:0100096 |
| T13 | 1923-1933 | Disease | denotes | SARS-CoV-2 | MONDO:0100096 |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-155 | Sentence | denotes | Utilization of a Glucometer Test Strip and Enzymatic Reactions to Quantify Anti-SARS-CoV-2 Spike RBD IgG Antibody and SARS-CoV-2 Virus in Saliva and Serum. |
| T2 | 156-370 | Sentence | denotes | A sensor capable of quantifying both anti-SARS-CoV-2 spike receptor-binding domain (RBD) antibody levels and the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus in saliva and serum was developed. |
| T3 | 371-631 | Sentence | denotes | This was accomplished by exploiting the enzymatic reaction of maltose and orthophosphate (PO43-) in the presence of maltose phosphorylase to generate an equivalent amount of glucose that was detected using a commercial glucometer test strip and a potentiostat. |
| T4 | 632-768 | Sentence | denotes | Important for this approach is the ability to generate PO43- in an amount that is directly related to the concentration of the analytes. |
| T5 | 769-1019 | Sentence | denotes | RBD-modified magnetic microparticles were used to capture anti-SARS-CoV-2 spike RBD antibodies, while particles modified with anti-SARS-CoV-2 nucleocapsid antibodies were used to capture SARS-CoV-2 nucleocapsid protein from inactivated virus samples. |
| T6 | 1020-1248 | Sentence | denotes | A magnet was used to isolate and purify the magnetic microparticles (with analyte attached), and alkaline phosphatase-conjugated secondary antibodies were bound to the analytes attached to the respective magnetic microparticles. |
| T7 | 1249-1466 | Sentence | denotes | Finally, through enzymatic reactions, specific amounts of PO43- (and subsequently glucose) were generated in proportion to the analyte concentration, which was then quantified using a commercial glucometer test strip. |
| T8 | 1467-1661 | Sentence | denotes | Utilizing glucose test strips makes the sensor relatively inexpensive, with a cost per test of ∼US $7 and ∼US $12 for quantifying anti-SARS-CoV-2 spike RBD antibody and SARS-CoV-2, respectively. |
| T9 | 1662-1891 | Sentence | denotes | Our sensor exhibited a limit of detection of 0.42 ng/mL for anti-SARS-CoV-2 spike RBD antibody, which is sensitive enough to quantify typical concentrations of antibodies in COVID-19-infected or vaccinated individuals (>1 μg/mL). |
| T10 | 1892-2047 | Sentence | denotes | The limit of detection for the SARS-CoV-2 virus is 300 pfu/mL (5.4 × 106 RNA copies/mL), which exceeds the performance recommended by the WHO (500 pfu/mL). |
| T11 | 2048-2252 | Sentence | denotes | In addition, the sensor exhibited good selectivity when challenged with competing analytes and could be used to quantify analytes in saliva and serum matrices with an accuracy of >94% compared to RT-qPCR. |
GlyCosmos15-FMA
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 138-144 | Body_part | denotes | Saliva | FMA:59862 |
| T2 | 149-154 | Body_part | denotes | Serum | FMA:63083 |
| T3 | 339-345 | Body_part | denotes | saliva | FMA:59862 |
| T4 | 350-355 | Body_part | denotes | serum | FMA:63083 |
| T5 | 2181-2187 | Body_part | denotes | saliva | FMA:59862 |
| T6 | 2192-2197 | Body_part | denotes | serum | FMA:63083 |
GlyCosmos15-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 138-144 | Body_part | denotes | Saliva | http://purl.obolibrary.org/obo/MAT_0000444 |
| T2 | 339-345 | Body_part | denotes | saliva | http://purl.obolibrary.org/obo/MAT_0000444 |
| T3 | 2181-2187 | Body_part | denotes | saliva | http://purl.obolibrary.org/obo/MAT_0000444 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 80-88 | OrganismTaxon | denotes | SARS-CoV | 694009 |
| T2 | 118-126 | OrganismTaxon | denotes | SARS-CoV | 694009 |
| T3 | 198-206 | OrganismTaxon | denotes | SARS-CoV | 694009 |
| T4 | 269-302 | OrganismTaxon | denotes | severe acute respiratory syndrome | 694009 |
| T5 | 318-326 | OrganismTaxon | denotes | SARS-CoV | 694009 |
| T6 | 832-840 | OrganismTaxon | denotes | SARS-CoV | 694009 |
| T7 | 900-908 | OrganismTaxon | denotes | SARS-CoV | 694009 |
| T8 | 956-964 | OrganismTaxon | denotes | SARS-CoV | 694009 |
| T9 | 1602-1610 | OrganismTaxon | denotes | SARS-CoV | 694009 |
| T10 | 1636-1644 | OrganismTaxon | denotes | SARS-CoV | 694009 |
| T11 | 1727-1735 | OrganismTaxon | denotes | SARS-CoV | 694009 |
| T12 | 1923-1931 | OrganismTaxon | denotes | SARS-CoV | 694009 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 138-144 | Body_part | denotes | Saliva | http://purl.obolibrary.org/obo/UBERON_0001836 |
| T2 | 339-345 | Body_part | denotes | saliva | http://purl.obolibrary.org/obo/UBERON_0001836 |
| T3 | 791-805 | Body_part | denotes | microparticles | http://purl.obolibrary.org/obo/GO_1903561 |
| T4 | 1073-1087 | Body_part | denotes | microparticles | http://purl.obolibrary.org/obo/GO_1903561 |
| T5 | 1233-1247 | Body_part | denotes | microparticles | http://purl.obolibrary.org/obo/GO_1903561 |
| T6 | 2181-2187 | Body_part | denotes | saliva | http://purl.obolibrary.org/obo/UBERON_0001836 |