> top > docs > PubMed:3567993 > annotations

PubMed:3567993 JSONTXT

Annnotations TAB JSON ListView MergeView

GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 327-334 Glycan_Motif denotes mannose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G70323CJ
T2 933-940 Glycan_Motif denotes mannose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G70323CJ
T3 982-989 Glycan_Motif denotes mannose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G70323CJ
T4 1104-1111 Glycan_Motif denotes mannose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G70323CJ
T5 1150-1157 Glycan_Motif denotes mannose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G70323CJ
T6 1231-1238 Glycan_Motif denotes mannose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G70323CJ
T7 1562-1569 Glycan_Motif denotes mannose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G70323CJ

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 327-334 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose
T2 933-940 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose
T3 982-989 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose
T4 1104-1111 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose
T5 1150-1157 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose
T6 1231-1238 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose
T7 1562-1569 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-130 Sentence denotes The conformation of glycans of the oligo-D-mannosidic type, and their interaction with concanavalin A: a computer-modelling study.
TextSentencer_T2 131-259 Sentence denotes The favored conformations of glycans of the oligo-D-mannosidic type have been determined by using empirical energy calculations.
TextSentencer_T3 260-505 Sentence denotes An interesting aspect is that the alpha-(1----3)-linked terminal D-mannose residue of the outer trimannosidic core fragment, in all the conformations which fall within 5 kcal.mol-1 of the global minimum, always lies close to the chitobiose core.
TextSentencer_T4 506-575 Sentence denotes These models are in general agreement with the available n.m.r. data.
TextSentencer_T5 576-855 Sentence denotes The probable modes of binding of these glycans to concanavalin A (Con A) were determined, by using a computer-modelling technique which identifies the positions for the different conformers of the carbohydrate in the binding site of Con A, based on stereochemical considerations.
TextSentencer_T6 856-1079 Sentence denotes These studies showed that Con A can bind only to two of the three terminal D-mannose residues in these glycans, because the D-mannose residue which lies close to the chitobiose core is inaccessible for the binding of Con A.
TextSentencer_T7 1080-1185 Sentence denotes Of these two terminal D-mannose residues, the alpha-(1----6)-linked D-mannose may bind the more strongly.
TextSentencer_T8 1186-1327 Sentence denotes Furthermore, it is shown that the internal D-mannose residue will, at best, interact very weakly with the carbohydrate-binding site of Con A.
TextSentencer_T9 1328-1428 Sentence denotes These results rationalize well the available data on the binding affinity of these glycans to Con A.
TextSentencer_T10 1429-1690 Sentence denotes They further support the conclusion that the binding affinity of a glycan to Con A does not depend on the number in the glycan, of D-mannose residues which possess free 3-, 4-, and 6-hydroxyl groups, but, rather, on the accessibility of these residues to Con A.
T1 0-130 Sentence denotes The conformation of glycans of the oligo-D-mannosidic type, and their interaction with concanavalin A: a computer-modelling study.
T2 131-259 Sentence denotes The favored conformations of glycans of the oligo-D-mannosidic type have been determined by using empirical energy calculations.
T3 260-505 Sentence denotes An interesting aspect is that the alpha-(1----3)-linked terminal D-mannose residue of the outer trimannosidic core fragment, in all the conformations which fall within 5 kcal.mol-1 of the global minimum, always lies close to the chitobiose core.
T4 506-575 Sentence denotes These models are in general agreement with the available n.m.r. data.
T5 576-855 Sentence denotes The probable modes of binding of these glycans to concanavalin A (Con A) were determined, by using a computer-modelling technique which identifies the positions for the different conformers of the carbohydrate in the binding site of Con A, based on stereochemical considerations.
T6 856-1079 Sentence denotes These studies showed that Con A can bind only to two of the three terminal D-mannose residues in these glycans, because the D-mannose residue which lies close to the chitobiose core is inaccessible for the binding of Con A.
T7 1080-1185 Sentence denotes Of these two terminal D-mannose residues, the alpha-(1----6)-linked D-mannose may bind the more strongly.
T8 1186-1327 Sentence denotes Furthermore, it is shown that the internal D-mannose residue will, at best, interact very weakly with the carbohydrate-binding site of Con A.
T9 1328-1428 Sentence denotes These results rationalize well the available data on the binding affinity of these glycans to Con A.
T10 1429-1690 Sentence denotes They further support the conclusion that the binding affinity of a glycan to Con A does not depend on the number in the glycan, of D-mannose residues which possess free 3-, 4-, and 6-hydroxyl groups, but, rather, on the accessibility of these residues to Con A.