| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1 |
0-138 |
Sentence |
denotes |
Comparison between Egg Intake versus Choline Supplementation on Gut Microbiota and Plasma Carotenoids in Subjects with Metabolic Syndrome. |
| T2 |
139-301 |
Sentence |
denotes |
We previously demonstrated that intake of three eggs/d for 4 weeks increased plasma choline and decreased inflammation in subjects with metabolic syndrome (MetS). |
| T3 |
302-576 |
Sentence |
denotes |
The purpose of the current study was to further explore the effects of phosphatidylcholine (PC) provided by eggs versus a choline bitartrate (CB) supplement on the gut microbiota, trimethylamine N-oxide (TMAO) formation, and plasma carotenoids lutein and zeaxanthin in MetS. |
| T4 |
577-661 |
Sentence |
denotes |
This randomized, controlled crossover clinical trial included 23 subjects with MetS. |
| T5 |
662-895 |
Sentence |
denotes |
Following a washout period of 2 weeks without consuming any choline-containing foods, subjects were randomly allocated to consume either three eggs/d or a CB supplement for 4 weeks (both diets had a choline equivalent of 400 mg/day). |
| T6 |
896-993 |
Sentence |
denotes |
DNA was extracted from stool samples to sequence the 16S rRNA gene region for community analysis. |
| T7 |
994-1103 |
Sentence |
denotes |
Operational taxonomic units (OTUs) and the α-diversity of the community were determined using QIIME software. |
| T8 |
1104-1259 |
Sentence |
denotes |
Plasma TMAO, methionine, betaine, and dimethylglycine (DMG) were quantified by stable isotope dilution liquid chromatography with tandem mass spectrometry. |
| T9 |
1260-1377 |
Sentence |
denotes |
Plasma carotenoids, lutein, and zeaxanthin were measured using reversed-phase high-performance liquid chromatography. |
| T10 |
1378-1526 |
Sentence |
denotes |
There were significant increases in plasma lutein and zeaxanthin after egg intake compared to the baseline or intake of CB supplement (p < 0.01). |
| T11 |
1527-1621 |
Sentence |
denotes |
In contrast, TMAO was not different between treatments compared to the baseline (p > 0.05). |
| T12 |
1622-1803 |
Sentence |
denotes |
Additionally, while diet intervention had no effects on microbiota diversity measures or relative taxa abundances, a correlation between bacterial biodiversity and HDL was observed. |
| T13 |
1804-1968 |
Sentence |
denotes |
Following egg intake, the observed increases in plasma lutein and zeaxanthin may suggest additional protection against oxidative stress, a common condition in MetS. |
| T1 |
0-138 |
Sentence |
denotes |
Comparison between Egg Intake versus Choline Supplementation on Gut Microbiota and Plasma Carotenoids in Subjects with Metabolic Syndrome. |
| T2 |
139-301 |
Sentence |
denotes |
We previously demonstrated that intake of three eggs/d for 4 weeks increased plasma choline and decreased inflammation in subjects with metabolic syndrome (MetS). |
| T3 |
302-576 |
Sentence |
denotes |
The purpose of the current study was to further explore the effects of phosphatidylcholine (PC) provided by eggs versus a choline bitartrate (CB) supplement on the gut microbiota, trimethylamine N-oxide (TMAO) formation, and plasma carotenoids lutein and zeaxanthin in MetS. |
| T4 |
577-661 |
Sentence |
denotes |
This randomized, controlled crossover clinical trial included 23 subjects with MetS. |
| T5 |
662-895 |
Sentence |
denotes |
Following a washout period of 2 weeks without consuming any choline-containing foods, subjects were randomly allocated to consume either three eggs/d or a CB supplement for 4 weeks (both diets had a choline equivalent of 400 mg/day). |
| T6 |
896-993 |
Sentence |
denotes |
DNA was extracted from stool samples to sequence the 16S rRNA gene region for community analysis. |
| T7 |
994-1103 |
Sentence |
denotes |
Operational taxonomic units (OTUs) and the α-diversity of the community were determined using QIIME software. |
| T8 |
1104-1259 |
Sentence |
denotes |
Plasma TMAO, methionine, betaine, and dimethylglycine (DMG) were quantified by stable isotope dilution liquid chromatography with tandem mass spectrometry. |
| T9 |
1260-1377 |
Sentence |
denotes |
Plasma carotenoids, lutein, and zeaxanthin were measured using reversed-phase high-performance liquid chromatography. |
| T10 |
1378-1526 |
Sentence |
denotes |
There were significant increases in plasma lutein and zeaxanthin after egg intake compared to the baseline or intake of CB supplement (p < 0.01). |
| T11 |
1527-1621 |
Sentence |
denotes |
In contrast, TMAO was not different between treatments compared to the baseline (p > 0.05). |
| T12 |
1622-1803 |
Sentence |
denotes |
Additionally, while diet intervention had no effects on microbiota diversity measures or relative taxa abundances, a correlation between bacterial biodiversity and HDL was observed. |
| T13 |
1804-1968 |
Sentence |
denotes |
Following egg intake, the observed increases in plasma lutein and zeaxanthin may suggest additional protection against oxidative stress, a common condition in MetS. |