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Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-132 Sentence denotes Immunomodulatory Effects of Omega-3 Fatty Acids in Patients with Differentiated Thyroid Cancer Before or After Radioiodine Ablation.
T2 133-144 Sentence denotes BACKGROUND:
T3 145-264 Sentence denotes Thyroid cancer and radioactive iodine (RAI) ablation for postsurgical management may lead to uncontrolled inflammation.
T4 265-275 Sentence denotes OBJECTIVE:
T5 276-444 Sentence denotes This study was intended to assess the prophylactic and therapeutic immunomodulatory effects of omega-3 fatty acids in patients with differentiated thyroid cancer (DTC).
T6 445-453 Sentence denotes METHODS:
T7 454-557 Sentence denotes A total of 85 patients with DTC were allocated into two groups based on RAI dosage after thyroidectomy.
T8 558-772 Sentence denotes Patients in each group were randomly distributed into three subgroups: G1 with RAI ablation only, G2 treated with omega-3 for 30 days before RAI ablation, and G3 treated with omega-3 for 30 days after RAI ablation.
T9 773-827 Sentence denotes Fifteen healthy individuals were included as controls.
T10 828-991 Sentence denotes Serum cytokine levels including IL-2, IL-4, IL-5, IL-6, IL-9, IL-10, IL-13, IL-17A, IL-17F, IL-21, IL-22, TNF-α and IFN-γ were determined by cytometric bead assay.
T11 992-1098 Sentence denotes RESULTS: IL-4, IL-6, IL-21 and IL-22 levels in patients with DTC were higher than in the healthy controls.
T12 1099-1176 Sentence denotes Regardless of RAI dosage, IL-6 showed an increasing trend after RAI ablation.
T13 1177-1288 Sentence denotes IL-4, IL-22, and IL-17A remained at considerably higher levels than in the healthy controls after RAI ablation.
T14 1289-1413 Sentence denotes Within-group comparisons showed a significant reduction in Th1+Th17/Th2+Th22 ratio in G2 patients 1 week after RAI ablation.
T15 1414-1540 Sentence denotes Between-group comparisons showed increased IL-10 levels in G3 compared with G1 patients one week after high-dose RAI ablation.
T16 1541-1687 Sentence denotes In G3, Th1+Th17/Th2+Th22 and Th1+Th17/Th2+Th9+Th22 ratios were remarkably lesser than in G2 patients 1 month after intermediate-dose RAI ablation.
T17 1688-1699 Sentence denotes CONCLUSION:
T18 1700-1886 Sentence denotes Our results showed better anti-inflammatory effects of omega-3 when it was used therapeutically after RAI ablation in patients with DTC than when it was used prophylactically before RAI.
T1 0-132 Sentence denotes Immunomodulatory Effects of Omega-3 Fatty Acids in Patients with Differentiated Thyroid Cancer Before or After Radioiodine Ablation.
T2 133-144 Sentence denotes BACKGROUND:
T3 145-264 Sentence denotes Thyroid cancer and radioactive iodine (RAI) ablation for postsurgical management may lead to uncontrolled inflammation.
T4 265-275 Sentence denotes OBJECTIVE:
T5 276-444 Sentence denotes This study was intended to assess the prophylactic and therapeutic immunomodulatory effects of omega-3 fatty acids in patients with differentiated thyroid cancer (DTC).
T6 445-453 Sentence denotes METHODS:
T7 454-557 Sentence denotes A total of 85 patients with DTC were allocated into two groups based on RAI dosage after thyroidectomy.
T8 558-772 Sentence denotes Patients in each group were randomly distributed into three subgroups: G1 with RAI ablation only, G2 treated with omega-3 for 30 days before RAI ablation, and G3 treated with omega-3 for 30 days after RAI ablation.
T9 773-827 Sentence denotes Fifteen healthy individuals were included as controls.
T10 828-991 Sentence denotes Serum cytokine levels including IL-2, IL-4, IL-5, IL-6, IL-9, IL-10, IL-13, IL-17A, IL-17F, IL-21, IL-22, TNF-α and IFN-γ were determined by cytometric bead assay.
T11 992-1098 Sentence denotes RESULTS: IL-4, IL-6, IL-21 and IL-22 levels in patients with DTC were higher than in the healthy controls.
T12 1099-1176 Sentence denotes Regardless of RAI dosage, IL-6 showed an increasing trend after RAI ablation.
T13 1177-1288 Sentence denotes IL-4, IL-22, and IL-17A remained at considerably higher levels than in the healthy controls after RAI ablation.
T14 1289-1413 Sentence denotes Within-group comparisons showed a significant reduction in Th1+Th17/Th2+Th22 ratio in G2 patients 1 week after RAI ablation.
T15 1414-1540 Sentence denotes Between-group comparisons showed increased IL-10 levels in G3 compared with G1 patients one week after high-dose RAI ablation.
T16 1541-1687 Sentence denotes In G3, Th1+Th17/Th2+Th22 and Th1+Th17/Th2+Th9+Th22 ratios were remarkably lesser than in G2 patients 1 month after intermediate-dose RAI ablation.
T17 1688-1699 Sentence denotes CONCLUSION:
T18 1700-1886 Sentence denotes Our results showed better anti-inflammatory effects of omega-3 when it was used therapeutically after RAI ablation in patients with DTC than when it was used prophylactically before RAI.

yangbin123xm_800_3

Id Subject Object Predicate Lexical cue
T1 65-94 DP denotes Differentiated Thyroid Cancer
T10 1755-1762 CI denotes omega-3
T11 733-740 CI denotes omega-3
T2 408-437 DP denotes differentiated thyroid cancer
T3 439-442 DP denotes DTC
T4 482-485 DP denotes DTC
T5 1053-1056 DP denotes DTC
T6 1832-1835 DP denotes DTC
T8 371-390 CI denotes omega-3 fatty acids
T9 672-679 CI denotes omega-3
T12 28-47 CI denotes Omega-3 Fatty Acids
T13 145-159 DP denotes Thyroid cancer

chenxin_473849_800_3

Id Subject Object Predicate Lexical cue
T1 28-47 CI denotes Omega-3 Fatty Acids
T10 439-442 DP denotes DTC
T11 482-485 DP denotes DTC
T12 1053-1056 DP denotes DTC
T13 1832-1835 DP denotes DTC
T2 371-390 CI denotes omega-3 fatty acids
T3 672-679 CI denotes omega-3
T5 733-740 CI denotes omega-3
T6 1755-1762 CI denotes omega-3
T7 145-159 DP denotes Thyroid cancer
T14 408-437 DP denotes differentiated thyroid cancer
T15 65-94 DP denotes Differentiated Thyroid Cancer