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PubMed:3524231 JSON TXT

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DisGeNET

Id	Subject	Object	Predicate	Lexical cue
T0	46-60	gene:2688	denotes	growth hormone
T1	13-40	disease:C0013264	denotes	Duchenne muscular dystrophy
T2	382-396	gene:2688	denotes	growth hormone
T3	374-377	disease:C0026850	denotes	DMD
T4	398-400	gene:2688	denotes	GH
T5	374-377	disease:C0026850	denotes	DMD
T6	1021-1023	gene:2688	denotes	GH
T7	1052-1055	disease:C0026850	denotes	DMD
R1	T0	T1	associated_with	growth hormone,Duchenne muscular dystrophy
R2	T2	T3	associated_with	growth hormone,DMD
R3	T4	T5	associated_with	GH,DMD
R4	T6	T7	associated_with	GH,DMD

performance-test

Id	Subject	Object	Predicate	Lexical cue
PD-UBERON-AE-B_T1	741-746	http://purl.obolibrary.org/obo/UBERON_0001977	denotes	serum

UBERON-AE

Id	Subject	Object	Predicate	Lexical cue
PD-UBERON-AE-B_T1	741-746	http://purl.obolibrary.org/obo/UBERON_0001977	denotes	serum

sentences

Id	Subject	Object	Predicate	Lexical cue
TextSentencer_T1	0-72	Sentence	denotes	Treatment of Duchenne muscular dystrophy with growth hormone inhibitors.
TextSentencer_T2	73-270	Sentence	denotes	A controlled, double-blind therapeutic trial with the drug mazindol, a growth hormone inhibitor, was performed in a pair of 7 1/2 year-old monozygotic twins, with Duchenne muscular dystrophy (DMD).
TextSentencer_T3	271-504	Sentence	denotes	The rationale for this trial was based on a patient (reported previously) affected simultaneously with DMD and growth hormone (GH) deficiency, who is showing a benign course of the dystrophic process and is still walking at 18 years.
TextSentencer_T4	505-590	Sentence	denotes	One of the twins received 2 mg of mazindol daily, while the other received a placebo.
TextSentencer_T5	591-769	Sentence	denotes	The assessment, repeated every 2 months, included weight and height measurements, functional and motor ability tests, ergometry and determinations of serum enzymes and GH levels.
TextSentencer_T6	770-967	Sentence	denotes	After one year of trial the code was broken and it was seen that the twin under placebo treatment was strikingly worse than his brother, the progression of whose condition was practically arrested.
TextSentencer_T7	968-1065	Sentence	denotes	These results strongly suggest that treatment with a GH inhibitor is beneficial for DMD patients.
T1	0-72	Sentence	denotes	Treatment of Duchenne muscular dystrophy with growth hormone inhibitors.
T2	73-270	Sentence	denotes	A controlled, double-blind therapeutic trial with the drug mazindol, a growth hormone inhibitor, was performed in a pair of 7 1/2 year-old monozygotic twins, with Duchenne muscular dystrophy (DMD).
T3	271-504	Sentence	denotes	The rationale for this trial was based on a patient (reported previously) affected simultaneously with DMD and growth hormone (GH) deficiency, who is showing a benign course of the dystrophic process and is still walking at 18 years.
T4	505-590	Sentence	denotes	One of the twins received 2 mg of mazindol daily, while the other received a placebo.
T5	591-769	Sentence	denotes	The assessment, repeated every 2 months, included weight and height measurements, functional and motor ability tests, ergometry and determinations of serum enzymes and GH levels.
T6	770-967	Sentence	denotes	After one year of trial the code was broken and it was seen that the twin under placebo treatment was strikingly worse than his brother, the progression of whose condition was practically arrested.
T7	968-1065	Sentence	denotes	These results strongly suggest that treatment with a GH inhibitor is beneficial for DMD patients.

PubCasesHPO

Id	Subject	Object	Predicate	Lexical cue
TI1	22-40	HP:0003560	denotes	muscular dystrophy
AB1	245-263	HP:0003560	denotes	muscular dystrophy

PubCasesORDO

Id	Subject	Object	Predicate	Lexical cue
TI1	13-40	ORDO:98896	denotes	Duchenne muscular dystrophy
AB1	236-263	ORDO:98896	denotes	Duchenne muscular dystrophy
AB2	265-268	ORDO:98896	denotes	DMD
AB3	374-377	ORDO:98896	denotes	DMD
AB4	1052-1055	ORDO:98896	denotes	DMD

NCBIDiseaseCorpus

Id	Subject	Object	Predicate	Lexical cue
T1	13-40	SpecificDisease:D020388	denotes	Duchenne muscular dystrophy
T2	236-263	SpecificDisease:D020388	denotes	Duchenne muscular dystrophy
T3	265-268	SpecificDisease:D020388	denotes	DMD
T4	374-377	SpecificDisease:D020388	denotes	DMD
T5	382-412	SpecificDisease:OMIM:262400	denotes	growth hormone (GH) deficiency
T6	452-470	DiseaseClass:D009136	denotes	dystrophic process
T7	1052-1055	Modifier:D020388	denotes	DMD

NCBI-Disease-Train

Id	Subject	Object	Predicate	Lexical cue	database_id
T3448	13-40	SpecificDisease	denotes	Duchenne muscular dystrophy	D020388
T3449	236-263	SpecificDisease	denotes	Duchenne muscular dystrophy	D020388
T3450	265-268	SpecificDisease	denotes	DMD	D020388
T3451	374-377	SpecificDisease	denotes	DMD	D020388
T3452	382-412	SpecificDisease	denotes	growth hormone (GH) deficiency	OMIM:262400
T3453	452-470	DiseaseClass	denotes	dystrophic process	D009136
T3454	1052-1055	Modifier	denotes	DMD	D020388

NCBI-Disease-Corpus-All

Id	Subject	Object	Predicate	Lexical cue	database_id
T3448	13-40	SpecificDisease	denotes	Duchenne muscular dystrophy	D020388
T3449	236-263	SpecificDisease	denotes	Duchenne muscular dystrophy	D020388
T3450	265-268	SpecificDisease	denotes	DMD	D020388
T3451	374-377	SpecificDisease	denotes	DMD	D020388
T3452	382-412	SpecificDisease	denotes	growth hormone (GH) deficiency	OMIM:262400
T3453	452-470	DiseaseClass	denotes	dystrophic process	D009136
T3454	1052-1055	Modifier	denotes	DMD	D020388

NCBI-Disease-Corpus-2stage-All

Id	Subject	Object	Predicate	Lexical cue
T1	13-40	SpecificDisease	denotes	Duchenne muscular dystrophy
T2	236-263	SpecificDisease	denotes	Duchenne muscular dystrophy
T3	265-268	SpecificDisease	denotes	DMD
T4	374-412	CompositeMention	denotes	DMD and growth hormone (GH) deficiency
T5	759-761	SpecificDisease	denotes	GH
T6	1021-1023	CompositeMention	denotes	GH
T7	1052-1055	SpecificDisease	denotes	DMD

NCBI-Disease-Corpus-rezarta-All

Id	Subject	Object	Predicate	Lexical cue
T1	13-40	SpecificDisease	denotes	Duchenne muscular dystrophy
T2	236-263	SpecificDisease	denotes	Duchenne muscular dystrophy
T3	265-268	Modifier	denotes	DMD
T4	374-377	Modifier	denotes	DMD
T5	1052-1055	Modifier	denotes	DMD

NCBI-Disease-Corpus-4oGuideline-All

Id	Subject	Object	Predicate	Lexical cue
T1	13-40	SpecificDisease	denotes	Duchenne muscular dystrophy
T2	236-269	SpecificDisease	denotes	Duchenne muscular dystrophy (DMD)
T3	374-377	SpecificDisease	denotes	DMD
T4	382-412	Modifier	denotes	growth hormone (GH) deficiency
T5	1052-1055	SpecificDisease	denotes	DMD

NCBI-Disease-Corpus-Simple-All

Id	Subject	Object	Predicate	Lexical cue
T1	13-40	SpecificDisease	denotes	Duchenne muscular dystrophy
T2	46-71	CompositeMention	denotes	growth hormone inhibitors
T3	144-168	CompositeMention	denotes	growth hormone inhibitor
T4	236-269	SpecificDisease	denotes	Duchenne muscular dystrophy (DMD)
T5	374-377	SpecificDisease	denotes	DMD
T6	382-412	SpecificDisease	denotes	growth hormone (GH) deficiency
T7	759-761	SpecificDisease	denotes	GH
T8	1021-1033	CompositeMention	denotes	GH inhibitor
T9	1052-1055	SpecificDisease	denotes	DMD