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Id Subject Object Predicate Lexical cue resolved_to
11268 1814-1818 Gene denotes LDHC 3948
11269 1820-1825 Gene denotes PDHA2 5161
11270 1827-1831 Gene denotes TNP1 7141
11271 1833-1837 Gene denotes TNP2 7142
11272 1839-1843 Gene denotes ODF1 4956
11273 1845-1849 Gene denotes ODF2 4957
11274 1851-1857 Gene denotes SPINK2 6691
11275 1859-1865 Gene denotes PCDHB3 56132
11276 1996-2001 Gene denotes ADAD1 132612
11277 2003-2008 Gene denotes BANF2 140836
11278 2010-2017 Gene denotes BCL2L14 79370
11279 2019-2027 Gene denotes C12orf50 160419
11280 2029-2038 Gene denotes C20orf173 140873
11281 2040-2048 Gene denotes C22orf23 84645
11282 2050-2057 Gene denotes C6orf99 100130967
11283 2059-2067 Gene denotes C9orf131 138724
11284 2069-2076 Gene denotes C9orf24 84688
11285 2078-2083 Gene denotes CABS1 85438
11286 2085-2091 Gene denotes CAPZA3 93661
11287 2093-2100 Gene denotes CCDC187 399693
11288 2102-2108 Gene denotes CCDC54 84692
11289 2110-2115 Gene denotes CDKN3 1033
11290 2117-2123 Gene denotes CEP170 9859
11291 2125-2132 Gene denotes CFAP206 154313
11292 2134-2140 Gene denotes CRISP2 7180
11293 2142-2146 Gene denotes CT83 203413
11294 2148-2155 Gene denotes CXorf65 158830
11295 2157-2164 Gene denotes FAM209A 200232
11296 2166-2173 Gene denotes FAM71F1 84691
11297 2175-2181 Gene denotes FAM81B 153643
11298 2183-2190 Gene denotes GALNTL5 168391
11299 2192-2197 Gene denotes GTSF1 121355
11300 2199-2204 Gene denotes H1FNT 341567
11301 2206-2211 Gene denotes HEMGN 55363
11302 2213-2218 Gene denotes HMGB4 127540
11303 2220-2225 Gene denotes KIF2B 84643
11304 2227-2231 Gene denotes LDHC 3948
11305 2233-2242 Gene denotes LOC441601 441601
11306 2244-2249 Gene denotes LYZL2 119180
11307 2251-2255 Gene denotes ODF1 4956
11308 2257-2261 Gene denotes ODF2 4957
11309 2263-2269 Gene denotes PCDHB3 56132
11310 2271-2276 Gene denotes PDHA2 5161
11311 2278-2282 Gene denotes PGK2 5232
11312 2284-2290 Gene denotes PIH1D2 120379
11313 2292-2297 Gene denotes PLCZ1 89869
11314 2299-2305 Gene denotes PROCA1 147011
11315 2307-2313 Gene denotes RIMBP3 85376
11316 2315-2321 Gene denotes ROPN1L 83853
11317 2323-2330 Gene denotes SHCBP1L 81626
11318 2332-2336 Gene denotes SMCP 4184
11319 2338-2345 Gene denotes SPATA16 83893
11320 2347-2354 Gene denotes SPATA19 219938
11321 2356-2362 Gene denotes SPINK2 6691
11322 2364-2369 Gene denotes TEX33 339669
11323 2371-2376 Gene denotes TKTL2 84076
11324 2378-2383 Gene denotes TMCO2 127391
11325 2385-2391 Gene denotes TMCO5A 145942
11326 2393-2397 Gene denotes TNP1 7141
11327 2399-2403 Gene denotes TNP2 7142
11328 2405-2412 Gene denotes TSPAN16 26526
11329 2414-2420 Gene denotes TSSK1B 83942
11330 2422-2427 Gene denotes TTLL2 83887
11331 2429-2435 Gene denotes UBQLN3 50613
11332 1581-1608 Disease denotes non-obstructive azoospermia MESH:D053713
11333 1731-1748 Disease denotes sperm dysfunction MESH:D009845
11334 1704-1729 Disease denotes spermatogenic dysfunction MESH:C564030
11335 1691-1694 Disease denotes NOA MESH:D053713
11336 208-224 Disease denotes male infertility MESH:D007248
11337 1973-1976 Disease denotes NOA MESH:D053713
11338 1641-1643 Disease denotes OA MESH:D053713
11339 1616-1639 Disease denotes obstructive azoospermia MESH:D053713
11340 408-424 Disease denotes male infertility MESH:D007248
11341 81-97 Disease denotes Male infertility MESH:D007248
11342 2784-2800 Disease denotes male infertility MESH:D007248
11343 1699-1701 Disease denotes OA MESH:D053713
11344 1321-1337 Disease denotes male infertility MESH:D007248
11345 1544-1560 Disease denotes male infertility MESH:D007248
11346 1646-1689 Disease denotes non-obstructive and obstructive azoospermia MESH:C536718
11347 1098-1114 Disease denotes male infertility MESH:D007248
11348 626-642 Disease denotes male infertility MESH:D007248
11349 2940-2956 Disease denotes male infertility MESH:D007248
11350 1984-1987 Disease denotes NOA MESH:D053713
11351 1610-1613 Disease denotes NOA MESH:D053713
11352 1992-1994 Disease denotes OA MESH:D053713
11528 2784-2800 Disease denotes male infertility MESH:D007248
11529 1098-1114 Disease denotes male infertility MESH:D007248
11567 1704-1729 Disease denotes spermatogenic dysfunction MESH:C564030
11579 1704-1729 Disease denotes spermatogenic dysfunction MESH:C564030

Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-27 Sentence denotes Omics and Male Infertility:
T2 28-80 Sentence denotes Highlighting the Application of Transcriptomic Data.
T3 81-191 Sentence denotes Male infertility is a multifaceted disorder affecting approximately 50% of male partners in infertile couples.
T4 192-449 Sentence denotes Over the years, male infertility has been diagnosed mainly through semen analysis, hormone evaluations, medical records and physical examinations, which of course are fundamental, but yet inefficient, because 30% of male infertility cases remain idiopathic.
T5 450-583 Sentence denotes This dilemmatic status of the unknown needs to be addressed with more sophisticated and result-driven technologies and/or techniques.
T6 584-739 Sentence denotes Genetic alterations have been linked with male infertility, thereby unveiling the practicality of investigating this disorder from the "omics" perspective.
T7 740-1014 Sentence denotes Omics aims at analyzing the structure and functions of a whole constituent of a given biological function at different levels, including the molecular gene level (genomics), transcript level (transcriptomics), protein level (proteomics) and metabolites level (metabolomics).
T8 1015-1244 Sentence denotes In the current study, an overview of the four branches of omics and their roles in male infertility are briefly discussed; the potential usefulness of assessing transcriptomic data to understand this pathology is also elucidated.
T9 1245-1463 Sentence denotes After assessing the publicly obtainable transcriptomic data for datasets on male infertility, a total of 1385 datasets were retrieved, of which 10 datasets met the inclusion criteria and were used for further analysis.
T10 1464-1561 Sentence denotes These datasets were classified into groups according to the disease or cause of male infertility.
T11 1562-1781 Sentence denotes The groups include non-obstructive azoospermia (NOA), obstructive azoospermia (OA), non-obstructive and obstructive azoospermia (NOA and OA), spermatogenic dysfunction, sperm dysfunction, and Y chromosome microdeletion.
T12 1782-1933 Sentence denotes Findings revealed that 8 genes (LDHC, PDHA2, TNP1, TNP2, ODF1, ODF2, SPINK2, PCDHB3) were commonly differentially expressed between all disease groups.
T13 1934-2437 Sentence denotes Likewise, 56 genes were common between NOA versus NOA and OA (ADAD1, BANF2, BCL2L14, C12orf50, C20orf173, C22orf23, C6orf99, C9orf131, C9orf24, CABS1, CAPZA3, CCDC187, CCDC54, CDKN3, CEP170, CFAP206, CRISP2, CT83, CXorf65, FAM209A, FAM71F1, FAM81B, GALNTL5, GTSF1, H1FNT, HEMGN, HMGB4, KIF2B, LDHC, LOC441601, LYZL2, ODF1, ODF2, PCDHB3, PDHA2, PGK2, PIH1D2, PLCZ1, PROCA1, RIMBP3, ROPN1L, SHCBP1L, SMCP, SPATA16, SPATA19, SPINK2, TEX33, TKTL2, TMCO2, TMCO5A, TNP1, TNP2, TSPAN16, TSSK1B, TTLL2, UBQLN3).
T14 2438-2686 Sentence denotes These genes, particularly the above-mentioned 8 genes, are involved in diverse biological processes such as germ cell development, spermatid development, spermatid differentiation, regulation of proteolysis, spermatogenesis and metabolic processes.
T15 2687-2801 Sentence denotes Owing to the stage-specific expression of these genes, any mal-expression can ultimately lead to male infertility.
T16 2802-3022 Sentence denotes Therefore, currently available data on all branches of omics relating to male fertility can be used to identify biomarkers for diagnosing male infertility, which can potentially help in unravelling some idiopathic cases.
T1 0-27 Sentence denotes Omics and Male Infertility:
T2 28-80 Sentence denotes Highlighting the Application of Transcriptomic Data.
T3 81-191 Sentence denotes Male infertility is a multifaceted disorder affecting approximately 50% of male partners in infertile couples.
T4 192-449 Sentence denotes Over the years, male infertility has been diagnosed mainly through semen analysis, hormone evaluations, medical records and physical examinations, which of course are fundamental, but yet inefficient, because 30% of male infertility cases remain idiopathic.
T5 450-583 Sentence denotes This dilemmatic status of the unknown needs to be addressed with more sophisticated and result-driven technologies and/or techniques.
T6 584-739 Sentence denotes Genetic alterations have been linked with male infertility, thereby unveiling the practicality of investigating this disorder from the "omics" perspective.
T7 740-1014 Sentence denotes Omics aims at analyzing the structure and functions of a whole constituent of a given biological function at different levels, including the molecular gene level (genomics), transcript level (transcriptomics), protein level (proteomics) and metabolites level (metabolomics).
T8 1015-1244 Sentence denotes In the current study, an overview of the four branches of omics and their roles in male infertility are briefly discussed; the potential usefulness of assessing transcriptomic data to understand this pathology is also elucidated.
T9 1245-1463 Sentence denotes After assessing the publicly obtainable transcriptomic data for datasets on male infertility, a total of 1385 datasets were retrieved, of which 10 datasets met the inclusion criteria and were used for further analysis.
T10 1464-1561 Sentence denotes These datasets were classified into groups according to the disease or cause of male infertility.
T11 1562-1781 Sentence denotes The groups include non-obstructive azoospermia (NOA), obstructive azoospermia (OA), non-obstructive and obstructive azoospermia (NOA and OA), spermatogenic dysfunction, sperm dysfunction, and Y chromosome microdeletion.
T12 1782-1933 Sentence denotes Findings revealed that 8 genes (LDHC, PDHA2, TNP1, TNP2, ODF1, ODF2, SPINK2, PCDHB3) were commonly differentially expressed between all disease groups.
T13 1934-2437 Sentence denotes Likewise, 56 genes were common between NOA versus NOA and OA (ADAD1, BANF2, BCL2L14, C12orf50, C20orf173, C22orf23, C6orf99, C9orf131, C9orf24, CABS1, CAPZA3, CCDC187, CCDC54, CDKN3, CEP170, CFAP206, CRISP2, CT83, CXorf65, FAM209A, FAM71F1, FAM81B, GALNTL5, GTSF1, H1FNT, HEMGN, HMGB4, KIF2B, LDHC, LOC441601, LYZL2, ODF1, ODF2, PCDHB3, PDHA2, PGK2, PIH1D2, PLCZ1, PROCA1, RIMBP3, ROPN1L, SHCBP1L, SMCP, SPATA16, SPATA19, SPINK2, TEX33, TKTL2, TMCO2, TMCO5A, TNP1, TNP2, TSPAN16, TSSK1B, TTLL2, UBQLN3).
T14 2438-2686 Sentence denotes These genes, particularly the above-mentioned 8 genes, are involved in diverse biological processes such as germ cell development, spermatid development, spermatid differentiation, regulation of proteolysis, spermatogenesis and metabolic processes.
T15 2687-2801 Sentence denotes Owing to the stage-specific expression of these genes, any mal-expression can ultimately lead to male infertility.
T16 2802-3022 Sentence denotes Therefore, currently available data on all branches of omics relating to male fertility can be used to identify biomarkers for diagnosing male infertility, which can potentially help in unravelling some idiopathic cases.