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Id Subject Object Predicate Lexical cue resolved_to
596 6-13 Gene denotes Adropin 375704
597 38-58 Disease denotes Rheumatoid Arthritis MESH:D001172
598 24-32 Species denotes Patients 9606
599 60-67 Gene denotes Adropin 375704
600 213-220 Gene denotes adropin 375704
601 328-335 Gene denotes adropin 375704
602 429-436 Gene denotes adropin 375704
603 541-548 Gene denotes adropin 375704
604 630-637 Gene denotes adropin 375704
605 782-789 Gene denotes adropin 375704
606 1111-1118 Gene denotes adropin 375704
607 1317-1324 Gene denotes adropin 375704
609 267-287 Disease denotes rheumatoid arthritis MESH:D001172
610 923-930 Chemical denotes glucose MESH:D005947
611 1374-1376 Disease denotes RA MESH:D001172
612 766-768 Disease denotes RA MESH:D001172
613 289-291 Disease denotes RA MESH:D001172
614 234-255 Disease denotes inflammatory diseases MESH:D007249
615 455-457 Disease denotes RA MESH:D001172
616 847-858 Chemical denotes cholesterol MESH:D002784
617 673-675 Disease denotes RA MESH:D001172
618 476-483 Chemical denotes glucose MESH:D005947
619 510-522 Disease denotes inflammatory MESH:D007249
620 1184-1191 Chemical denotes glucose MESH:D005947
621 676-684 Species denotes patients 9606
622 354-362 Species denotes patients 9606
623 1011-1029 Disease denotes insulin resistance MESH:D007333
624 368-370 Disease denotes RA MESH:D001172
763 630-637 Gene denotes adropin 375704
764 676-684 Species denotes patients 9606
765 682-684 Disease denotes ts MESH:D001172
766 782-789 Gene denotes adropin 375704
767 1111-1118 Gene denotes adropin 375704
768 847-858 Chemical denotes cholesterol MESH:D002784
769 923-930 Chemical denotes glucose MESH:D005947
1009 1011-1018 Gene denotes insulin 3630
1021 6-13 Gene denotes Adropin 375704
1027 6-13 Gene denotes Adropin 375704
1039 1011-1018 Gene denotes insulin 3630
1073 1111-1118 Gene denotes adropin 375704

Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-59 Sentence denotes Serum Adropin Levels in Patients with Rheumatoid Arthritis.
T2 60-160 Sentence denotes Adropin is a secretory protein that mainly modulates metabolic homeostasis and endothelial function.
T3 161-293 Sentence denotes There is growing evidence supporting association of adropin with various inflammatory diseases, including rheumatoid arthritis (RA).
T4 294-403 Sentence denotes This study aimed to compare serum adropin levels between 70 patients with RA and 70 matched healthy controls.
T5 404-534 Sentence denotes Furthermore, we explored adropin correlations with RA disease activity, glucose metabolism parameters and inflammatory biomarkers.
T6 535-623 Sentence denotes Serum adropin levels were determined by a competitive enzyme-linked immunosorbent assay.
T7 624-758 Sentence denotes Serum adropin levels were significantly lower in RA patients than in the control group (2.85 ± 0.91 vs. 4.02 ± 0.99 ng/mL, p < 0.001).
T8 759-1056 Sentence denotes In the RA group, serum adropin levels had a significant negative correlation with total cholesterol (r = -0.172, p = 0.043), HbA1c (r = -0.406, p < 0.001), fasting glucose (r = -0.377, p < 0.001) and HOMA-IR (the homeostasis model assessment-estimated insulin resistance; (r = -0.315, p = 0.008)).
T9 1057-1290 Sentence denotes Multiple linear regression analysis showed that serum adropin levels retained a significant association with levels of fasting glucose (β ± SE, -0.450 ± 0.140, p = 0.002) and HbA1c (-0.528 ± 0.223, p = 0.021) after model adjustments.
T10 1291-1458 Sentence denotes These findings imply that adropin could have an impact on metabolic homeostasis in RA, although further well-designed studies are warranted in order to establish this.
T1 0-59 Sentence denotes Serum Adropin Levels in Patients with Rheumatoid Arthritis.
T2 60-160 Sentence denotes Adropin is a secretory protein that mainly modulates metabolic homeostasis and endothelial function.
T3 161-293 Sentence denotes There is growing evidence supporting association of adropin with various inflammatory diseases, including rheumatoid arthritis (RA).
T4 294-403 Sentence denotes This study aimed to compare serum adropin levels between 70 patients with RA and 70 matched healthy controls.
T5 404-534 Sentence denotes Furthermore, we explored adropin correlations with RA disease activity, glucose metabolism parameters and inflammatory biomarkers.
T6 535-623 Sentence denotes Serum adropin levels were determined by a competitive enzyme-linked immunosorbent assay.
T7 624-758 Sentence denotes Serum adropin levels were significantly lower in RA patients than in the control group (2.85 ± 0.91 vs. 4.02 ± 0.99 ng/mL, p < 0.001).
T8 759-1056 Sentence denotes In the RA group, serum adropin levels had a significant negative correlation with total cholesterol (r = -0.172, p = 0.043), HbA1c (r = -0.406, p < 0.001), fasting glucose (r = -0.377, p < 0.001) and HOMA-IR (the homeostasis model assessment-estimated insulin resistance; (r = -0.315, p = 0.008)).
T9 1057-1290 Sentence denotes Multiple linear regression analysis showed that serum adropin levels retained a significant association with levels of fasting glucose (β ± SE, -0.450 ± 0.140, p = 0.002) and HbA1c (-0.528 ± 0.223, p = 0.021) after model adjustments.
T10 1291-1458 Sentence denotes These findings imply that adropin could have an impact on metabolic homeostasis in RA, although further well-designed studies are warranted in order to establish this.