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Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-212 Sentence denotes Effect of high-intensity exercise on cardiorespiratory fitness, cardiovascular disease risk and disease activity in patients with inflammatory joint disease: protocol for the ExeHeart randomised controlled trial.
T2 213-226 Sentence denotes INTRODUCTION:
T3 227-402 Sentence denotes Inflammatory joint disease (IJD) is associated with increased risk of cardiovascular disease (CVD) fostered by systemic inflammation and a high prevalence of CVD risk factors.
T4 403-529 Sentence denotes Cardiorespiratory fitness (CRF) is an important health parameter and CRF-measures are advocated in routine health evaluations.
T5 530-679 Sentence denotes CRF associates with CVD risk, and exercise modalities such as high intensity interval training (HIIT) can increase CRF and mitigate CVD risk factors.
T6 680-786 Sentence denotes In IJD, exercise is rarely used in CVD risk management and the cardioprotective effect of HIIT is unclear.
T7 787-906 Sentence denotes Furthermore, the clinical applicability of HIIT to primary care settings is largely unknown and warrants investigation.
T8 907-995 Sentence denotes The primary aim is to assess the effect of a HIIT programme on CRF in patients with IJD.
T9 996-1195 Sentence denotes Second, we will evaluate the effect of HIIT on CVD risk and disease activity in patients with IJD, feasibility of HIIT in primary care and validity of non-exercise algorithms to detect change in CRF.
T10 1196-1217 Sentence denotes METHODS AND ANALYSIS:
T11 1218-1276 Sentence denotes ExeHeart is a single-blinded, randomised controlled trial.
T12 1277-1394 Sentence denotes Sixty patients with IJD will be recruited from the Preventive Cardio-Rheuma clinic at Diakonhjemmet Hospital, Norway.
T13 1395-1593 Sentence denotes Patients will be assigned to receive standard care (relevant lifestyle advice and cardio-preventive medication) or standard care plus a 12-week HIIT intervention by physiotherapists in primary care.
T14 1594-1657 Sentence denotes HIIT sessions will be prescribed at 90%-95% of peak heart rate.
T15 1658-1942 Sentence denotes Outcomes include CRF (primary outcome), CVD risk factors, anthropometric measures, disease activity and patient-reported outcomes related to pain, fatigue, disease, physical activity and exercise and will be assessed at baseline, 3 months (primary endpoint) and 6 months postbaseline.
T16 1943-1968 Sentence denotes ETHICS AND DISSEMINATION:
T17 1969-2080 Sentence denotes Ethical approval has been obtained from the Regional Committee for Medical and Health Research Ethics (201227).
T18 2081-2147 Sentence denotes Participants are required to sign a written informed consent form.
T19 2148-2276 Sentence denotes Results will be discussed with patient representatives, submitted to peer-reviewed journals and presented at relevant platforms.
T20 2277-2316 Sentence denotes TRIAL REGISTRATION NUMBER: NCT04922840.
T1 0-212 Sentence denotes Effect of high-intensity exercise on cardiorespiratory fitness, cardiovascular disease risk and disease activity in patients with inflammatory joint disease: protocol for the ExeHeart randomised controlled trial.
T2 213-226 Sentence denotes INTRODUCTION:
T3 227-402 Sentence denotes Inflammatory joint disease (IJD) is associated with increased risk of cardiovascular disease (CVD) fostered by systemic inflammation and a high prevalence of CVD risk factors.
T4 403-529 Sentence denotes Cardiorespiratory fitness (CRF) is an important health parameter and CRF-measures are advocated in routine health evaluations.
T5 530-679 Sentence denotes CRF associates with CVD risk, and exercise modalities such as high intensity interval training (HIIT) can increase CRF and mitigate CVD risk factors.
T6 680-786 Sentence denotes In IJD, exercise is rarely used in CVD risk management and the cardioprotective effect of HIIT is unclear.
T7 787-906 Sentence denotes Furthermore, the clinical applicability of HIIT to primary care settings is largely unknown and warrants investigation.
T8 907-995 Sentence denotes The primary aim is to assess the effect of a HIIT programme on CRF in patients with IJD.
T9 996-1195 Sentence denotes Second, we will evaluate the effect of HIIT on CVD risk and disease activity in patients with IJD, feasibility of HIIT in primary care and validity of non-exercise algorithms to detect change in CRF.
T10 1196-1217 Sentence denotes METHODS AND ANALYSIS:
T11 1218-1276 Sentence denotes ExeHeart is a single-blinded, randomised controlled trial.
T12 1277-1394 Sentence denotes Sixty patients with IJD will be recruited from the Preventive Cardio-Rheuma clinic at Diakonhjemmet Hospital, Norway.
T13 1395-1593 Sentence denotes Patients will be assigned to receive standard care (relevant lifestyle advice and cardio-preventive medication) or standard care plus a 12-week HIIT intervention by physiotherapists in primary care.
T14 1594-1657 Sentence denotes HIIT sessions will be prescribed at 90%-95% of peak heart rate.
T15 1658-1942 Sentence denotes Outcomes include CRF (primary outcome), CVD risk factors, anthropometric measures, disease activity and patient-reported outcomes related to pain, fatigue, disease, physical activity and exercise and will be assessed at baseline, 3 months (primary endpoint) and 6 months postbaseline.
T16 1943-1968 Sentence denotes ETHICS AND DISSEMINATION:
T17 1969-2080 Sentence denotes Ethical approval has been obtained from the Regional Committee for Medical and Health Research Ethics (201227).
T18 2081-2147 Sentence denotes Participants are required to sign a written informed consent form.
T19 2148-2276 Sentence denotes Results will be discussed with patient representatives, submitted to peer-reviewed journals and presented at relevant platforms.
T20 2277-2316 Sentence denotes TRIAL REGISTRATION NUMBER: NCT04922840.

Zierdiyeerkenaili_800_3

Id Subject Object Predicate Lexical cue
T1 255-258 DP denotes IJD
T2 683-686 DP denotes IJD
T3 991-994 DP denotes IJD
T4 1090-1093 DP denotes IJD
T5 1297-1300 DP denotes IJD
T6 227-253 DP denotes Inflammatory joint disease
T7 130-156 DP denotes inflammatory joint disease

yaoziqian_800_3

Id Subject Object Predicate Lexical cue
T1 130-156 DP denotes inflammatory joint disease
T2 227-253 DP denotes Inflammatory joint disease
T3 255-258 DP denotes IJD
T5 991-994 DP denotes IJD
T6 1297-1300 DP denotes IJD
T7 683-686 DP denotes IJD
T8 1090-1093 DP denotes IJD