PubMed:34526539
Annnotations
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 85-92 | Disease | denotes | amyloid | http://purl.obolibrary.org/obo/MONDO_0019065 |
| T2 | 107-126 | Disease | denotes | Alzheimer's disease | http://purl.obolibrary.org/obo/MONDO_0004975 |
| T3 | 185-192 | Disease | denotes | Amyloid | http://purl.obolibrary.org/obo/MONDO_0019065 |
| T4 | 216-223 | Disease | denotes | amyloid | http://purl.obolibrary.org/obo/MONDO_0019065 |
| T5 | 292-309 | Disease | denotes | Alzheimer Disease | http://purl.obolibrary.org/obo/MONDO_0004975 |
| T6 | 349-356 | Disease | denotes | amyloid | http://purl.obolibrary.org/obo/MONDO_0019065 |
| T7 | 371-390 | Disease | denotes | Alzheimer's disease | http://purl.obolibrary.org/obo/MONDO_0004975 |
| T8 | 569-576 | Disease | denotes | amyloid | http://purl.obolibrary.org/obo/MONDO_0019065 |
HP-phenotype
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 107-126 | Phenotype | denotes | Alzheimer's disease | HP:0002511 |
| T2 | 237-260 | Phenotype | denotes | neurofibrillary tangles | HP:0002185 |
| T3 | 292-309 | Phenotype | denotes | Alzheimer Disease | HP:0002511 |
| T4 | 371-390 | Phenotype | denotes | Alzheimer's disease | HP:0002511 |
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 600-605 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/MAT_0000098 |
| T2 | 1149-1164 | Body_part | denotes | cerebral cortex | http://purl.obolibrary.org/obo/MAT_0000108 |
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 887-894 | Glycan | denotes | maltose | https://api.glycosmos.org/wurcs2image/latest/png/binary/G44653LT |
GlyCosmos15-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 107-126 | Phenotype | denotes | Alzheimer's disease | HP:0002511 |
| T2 | 237-260 | Phenotype | denotes | neurofibrillary tangles | HP:0002185 |
| T3 | 292-309 | Phenotype | denotes | Alzheimer Disease | HP:0002511 |
| T4 | 371-390 | Phenotype | denotes | Alzheimer's disease | HP:0002511 |
GlyCosmos15-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 85-92 | Disease | denotes | amyloid | http://purl.obolibrary.org/obo/MONDO_0019065 |
| T2 | 107-126 | Disease | denotes | Alzheimer's disease | http://purl.obolibrary.org/obo/MONDO_0004975 |
| T3 | 185-192 | Disease | denotes | Amyloid | http://purl.obolibrary.org/obo/MONDO_0019065 |
| T4 | 216-223 | Disease | denotes | amyloid | http://purl.obolibrary.org/obo/MONDO_0019065 |
| T5 | 292-309 | Disease | denotes | Alzheimer Disease | http://purl.obolibrary.org/obo/MONDO_0004975 |
| T6 | 349-356 | Disease | denotes | amyloid | http://purl.obolibrary.org/obo/MONDO_0019065 |
| T7 | 371-390 | Disease | denotes | Alzheimer's disease | http://purl.obolibrary.org/obo/MONDO_0004975 |
| T8 | 569-576 | Disease | denotes | amyloid | http://purl.obolibrary.org/obo/MONDO_0019065 |
GlyCosmos15-NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 138-142 | OrganismTaxon | denotes | mice | 10088 |
| T2 | 628-632 | OrganismTaxon | denotes | mice | 10088 |
| T3 | 667-671 | OrganismTaxon | denotes | mice | 10088 |
| T4 | 956-960 | OrganismTaxon | denotes | mice | 10088 |
| T5 | 1213-1217 | OrganismTaxon | denotes | mice | 10088 |
GlyCosmos15-CL
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 839-843 | Cell | denotes | poly | http://purl.obolibrary.org/obo/CL:0000096|http://purl.obolibrary.org/obo/CL:0000775 |
GlyCosmos15-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 600-605 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/UBERON_0000955|http://purl.obolibrary.org/obo/UBERON_6110636 |
| T3 | 895-900 | Body_part | denotes | shell | http://purl.obolibrary.org/obo/UBERON_0006611|http://purl.obolibrary.org/obo/UBERON_0006612 |
| T5 | 1149-1164 | Body_part | denotes | cerebral cortex | http://purl.obolibrary.org/obo/UBERON_0000956 |
GlyCosmos15-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 600-605 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/MAT_0000098 |
| T2 | 1149-1164 | Body_part | denotes | cerebral cortex | http://purl.obolibrary.org/obo/MAT_0000108 |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-184 | Sentence | denotes | In situ identification and G4-PPI-His-Mal-dendrimer-induced reduction of early-stage amyloid aggregates in Alzheimer's disease transgenic mice using synchrotron-based infrared imaging. |
| T2 | 185-465 | Sentence | denotes | Amyloid plaques composed of Aβ amyloid peptides and neurofibrillary tangles are a pathological hallmark of Alzheimer Disease. In situ identification of early-stage amyloid aggregates in Alzheimer's disease is relevant for their importance as potential targets for effective drugs. |
| T3 | 466-652 | Sentence | denotes | Synchrotron-based infrared imaging is here used to identify early-stage oligomeric/granular aggregated amyloid species in situ in the brain of APP/PS1 transgenic mice for the first time. |
| T4 | 653-718 | Sentence | denotes | Also, APP/PS1 mice show fibrillary aggregates at 6 and 12 months. |
| T5 | 719-1035 | Sentence | denotes | A significant decreased burden of early-stage aggregates and fibrillary aggregates is obtained following treatment with poly(propylene imine) dendrimers with histidine-maltose shell (a neurodegenerative protector) in 6-month-old APP/PS1 mice, thus demonstrating their putative therapeutic properties of in AD models. |
| T6 | 1036-1279 | Sentence | denotes | Identification, localization, and characterization using infrared imaging of these non-fibrillary species in the cerebral cortex at early stages of AD progression in transgenic mice point to their relevance as putative pharmacological targets. |
| T7 | 1280-1414 | Sentence | denotes | No less important, early detection of these structures may be useful in the search for markers for non-invasive diagnostic techniques. |
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 887-894 | Glycan | denotes | maltose | https://api.glycosmos.org/wurcs2image/latest/png/binary/G44653LT |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 138-142 | OrganismTaxon | denotes | mice | 10088 |
| T2 | 628-632 | OrganismTaxon | denotes | mice | 10088 |
| T3 | 667-671 | OrganismTaxon | denotes | mice | 10088 |
| T4 | 956-960 | OrganismTaxon | denotes | mice | 10088 |
| T5 | 1213-1217 | OrganismTaxon | denotes | mice | 10088 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 600-605 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/UBERON_0000955|http://purl.obolibrary.org/obo/UBERON_6110636 |
| T3 | 895-900 | Body_part | denotes | shell | http://purl.obolibrary.org/obo/UBERON_0006611|http://purl.obolibrary.org/obo/UBERON_0006612 |
| T5 | 1149-1164 | Body_part | denotes | cerebral cortex | http://purl.obolibrary.org/obo/UBERON_0000956 |
CL-cell
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 839-843 | Cell | denotes | poly | http://purl.obolibrary.org/obo/CL:0000096|http://purl.obolibrary.org/obo/CL:0000775 |