PubMed:34257400
Annnotations
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 76-88 | Disease | denotes | preeclampsia | http://purl.obolibrary.org/obo/MONDO_0005081 |
| T2 | 96-120 | Disease | denotes | fetal growth restriction | http://purl.obolibrary.org/obo/MONDO_0005030 |
| T3 | 122-134 | Disease | denotes | Preeclampsia | http://purl.obolibrary.org/obo/MONDO_0005081 |
| T4 | 136-138 | Disease | denotes | PE | http://purl.obolibrary.org/obo/MONDO_0005081 |
| T5 | 144-168 | Disease | denotes | fetal growth restriction | http://purl.obolibrary.org/obo/MONDO_0005030 |
| T6 | 170-173 | Disease | denotes | FGR | http://purl.obolibrary.org/obo/MONDO_0005030 |
| T7 | 382-385 | Disease | denotes | FGR | http://purl.obolibrary.org/obo/MONDO_0005030 |
| T8 | 387-389 | Disease | denotes | PE | http://purl.obolibrary.org/obo/MONDO_0005081 |
| T9 | 398-401 | Disease | denotes | FGR | http://purl.obolibrary.org/obo/MONDO_0005030 |
| T10 | 403-405 | Disease | denotes | PE | http://purl.obolibrary.org/obo/MONDO_0005081 |
| T11 | 408-411 | Disease | denotes | FGR | http://purl.obolibrary.org/obo/MONDO_0005030 |
| T12 | 997-999 | Disease | denotes | PE | http://purl.obolibrary.org/obo/MONDO_0005081 |
| T13 | 1012-1015 | Disease | denotes | FGR | http://purl.obolibrary.org/obo/MONDO_0005030 |
| T14 | 1041-1044 | Disease | denotes | FGR | http://purl.obolibrary.org/obo/MONDO_0005030 |
| T15 | 1048-1050 | Disease | denotes | PE | http://purl.obolibrary.org/obo/MONDO_0005081 |
| T16 | 1381-1384 | Disease | denotes | FGR | http://purl.obolibrary.org/obo/MONDO_0005030 |
| T17 | 1431-1433 | Disease | denotes | PE | http://purl.obolibrary.org/obo/MONDO_0005081 |
| T18 | 1566-1569 | Disease | denotes | FGR | http://purl.obolibrary.org/obo/MONDO_0005030 |
| T19 | 1734-1736 | Disease | denotes | PE | http://purl.obolibrary.org/obo/MONDO_0005081 |
| T20 | 1741-1744 | Disease | denotes | FGR | http://purl.obolibrary.org/obo/MONDO_0005030 |
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 184-192 | Body_part | denotes | placenta | http://purl.obolibrary.org/obo/MAT_0000279 |
| T2 | 1016-1023 | Body_part | denotes | fetuses | http://purl.obolibrary.org/obo/MAT_0000399 |
| T3 | 1404-1411 | Body_part | denotes | fetuses | http://purl.obolibrary.org/obo/MAT_0000399 |
| T4 | 1570-1577 | Body_part | denotes | fetuses | http://purl.obolibrary.org/obo/MAT_0000399 |
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 1209-1215 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
GlyCosmos15-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 76-88 | Disease | denotes | preeclampsia | MONDO:0005081 |
| T2 | 96-120 | Disease | denotes | fetal growth restriction | MONDO:0005030 |
| T3 | 122-134 | Disease | denotes | Preeclampsia | MONDO:0005081 |
| T4 | 136-138 | Disease | denotes | PE | MONDO:0005081 |
| T5 | 144-168 | Disease | denotes | fetal growth restriction | MONDO:0005030 |
| T6 | 170-173 | Disease | denotes | FGR | MONDO:0005030 |
| T7 | 382-385 | Disease | denotes | FGR | MONDO:0005030 |
| T8 | 387-389 | Disease | denotes | PE | MONDO:0005081 |
| T9 | 398-401 | Disease | denotes | FGR | MONDO:0005030 |
| T10 | 403-405 | Disease | denotes | PE | MONDO:0005081 |
| T11 | 408-411 | Disease | denotes | FGR | MONDO:0005030 |
| T12 | 997-999 | Disease | denotes | PE | MONDO:0005081 |
| T13 | 1012-1015 | Disease | denotes | FGR | MONDO:0005030 |
| T14 | 1041-1044 | Disease | denotes | FGR | MONDO:0005030 |
| T15 | 1048-1050 | Disease | denotes | PE | MONDO:0005081 |
| T16 | 1381-1384 | Disease | denotes | FGR | MONDO:0005030 |
| T17 | 1431-1433 | Disease | denotes | PE | MONDO:0005081 |
| T18 | 1566-1569 | Disease | denotes | FGR | MONDO:0005030 |
| T19 | 1734-1736 | Disease | denotes | PE | MONDO:0005081 |
| T20 | 1741-1744 | Disease | denotes | FGR | MONDO:0005030 |
GlyCosmos15-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 61-72 | Body_part | denotes | fingerprint | http://purl.obolibrary.org/obo/UBERON_0013487 |
| T2 | 184-192 | Body_part | denotes | placenta | http://purl.obolibrary.org/obo/UBERON_0001987 |
| T3 | 511-517 | Body_part | denotes | plasma | http://purl.obolibrary.org/obo/UBERON_0001969 |
GlyCosmos15-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 184-192 | Body_part | denotes | placenta | http://purl.obolibrary.org/obo/MAT_0000279 |
| T2 | 1016-1023 | Body_part | denotes | fetuses | http://purl.obolibrary.org/obo/MAT_0000399 |
| T3 | 1404-1411 | Body_part | denotes | fetuses | http://purl.obolibrary.org/obo/MAT_0000399 |
| T4 | 1570-1577 | Body_part | denotes | fetuses | http://purl.obolibrary.org/obo/MAT_0000399 |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-121 | Sentence | denotes | Paired maternal and fetal metabolomics reveal a differential fingerprint in preeclampsia versus fetal growth restriction. |
| T2 | 122-238 | Sentence | denotes | Preeclampsia (PE) and fetal growth restriction (FGR) are both placenta-mediated disorders with unclear pathogenesis. |
| T3 | 239-324 | Sentence | denotes | Metabolomics of maternal and fetal pairs might help in understanding these disorders. |
| T4 | 325-454 | Sentence | denotes | We recruited prospectively pregnancies with normotensive FGR, PE without FGR, PE + FGR and uncomplicated pregnancies as controls. |
| T5 | 455-548 | Sentence | denotes | Nuclear magnetic resonance metabolomics were applied on plasma samples collected at delivery. |
| T6 | 549-645 | Sentence | denotes | Advanced lipoprotein, glycoprotein and choline profiling was performed using the Liposcale test. |
| T7 | 646-732 | Sentence | denotes | The software package Dolphin was used to quantify 24 low-molecular-weight metabolites. |
| T8 | 733-889 | Sentence | denotes | Statistical analysis comprised the comparison between each group of complicated pregnancies versus controls, considering 5% false discovery rate correction. |
| T9 | 890-982 | Sentence | denotes | Lipid profiles were altered in accordance with the clinical presentation of these disorders. |
| T10 | 983-1279 | Sentence | denotes | Specifically, PE mothers and FGR fetuses (with or without FGR or PE, respectively) exhibited a pro-atherogenic and pro-inflammatory profile, with higher concentrations of triglycerides, remnant cholesterol (VLDL, IDL) and Glc/GalNAc-linked and lipid-associated glycoproteins compared to controls. |
| T11 | 1280-1385 | Sentence | denotes | Low-molecular-weight metabolites were extensively disturbed in preeclamptic mothers, with or without FGR. |
| T12 | 1386-1658 | Sentence | denotes | Growth restricted fetuses in the presence of PE showed changes in low-molecular-weight metabolites similar to their mothers (increased creatine and creatinine), while normotensive FGR fetuses presented scarce differences, consistent with undernutrition (lower isoleucine). |
| T13 | 1659-1745 | Sentence | denotes | Further research is warranted to clarify maternal and fetal adaptations to PE and FGR. |
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 1209-1215 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 61-72 | Body_part | denotes | fingerprint | http://purl.obolibrary.org/obo/UBERON_0013487 |
| T2 | 184-192 | Body_part | denotes | placenta | http://purl.obolibrary.org/obo/UBERON_0001987 |
| T3 | 511-517 | Body_part | denotes | plasma | http://purl.obolibrary.org/obo/UBERON_0001969 |