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sentences

Id Subject Object Predicate Lexical cue
T1 0-93 Sentence denotes Biochemical and amino acid sequence analysis of human eosinophil granule major basic protein.
T2 94-272 Sentence denotes Eosinophil granule major basic protein (MBP) is a relatively low molecular weight cationic (pI greater than 10) protein present in the crystalloid core of the eosinophil granule.
T3 273-455 Sentence denotes Amino acid sequence analysis of this protein was undertaken as part of an analysis of the structural basis of the potent cytotoxic activities of MBP on parasites and mammalian cells.
T4 456-622 Sentence denotes Many conventional sequencing strategies were unworkable because of the unusual amino acid composition of MBP and its insolubility in solutions buffered at neutral pH.
T5 623-864 Sentence denotes Less conventional chemical reactions, including cyanogen bromide-induced cleavage at tryptophan and acid-induced cleavage at aspartic acid, were used successfully to obtain peptides which allowed definition of the amino acid sequence of MBP.
T6 865-1065 Sentence denotes Characterization of MBP by reverse-phase high pressure liquid chromatography and two-dimensional gel analysis showed no microheterogeneity that might be attributed to post-translational modifications.
T7 1066-1218 Sentence denotes Comparison of the MBP sequence with a protein sequence data base showed that MBP has no significant sequence homology with other characterized proteins.
T8 1219-1411 Sentence denotes The basicity (pI 10.9) and hydrophobicity predicted from the MBP sequence are likely responsible for the observed affinity of this cytotoxic molecule for cell surfaces and some serum proteins.
T1 0-93 Sentence denotes Biochemical and amino acid sequence analysis of human eosinophil granule major basic protein.
T2 94-272 Sentence denotes Eosinophil granule major basic protein (MBP) is a relatively low molecular weight cationic (pI greater than 10) protein present in the crystalloid core of the eosinophil granule.
T3 273-455 Sentence denotes Amino acid sequence analysis of this protein was undertaken as part of an analysis of the structural basis of the potent cytotoxic activities of MBP on parasites and mammalian cells.
T4 456-622 Sentence denotes Many conventional sequencing strategies were unworkable because of the unusual amino acid composition of MBP and its insolubility in solutions buffered at neutral pH.
T5 623-864 Sentence denotes Less conventional chemical reactions, including cyanogen bromide-induced cleavage at tryptophan and acid-induced cleavage at aspartic acid, were used successfully to obtain peptides which allowed definition of the amino acid sequence of MBP.
T6 865-1065 Sentence denotes Characterization of MBP by reverse-phase high pressure liquid chromatography and two-dimensional gel analysis showed no microheterogeneity that might be attributed to post-translational modifications.
T7 1066-1218 Sentence denotes Comparison of the MBP sequence with a protein sequence data base showed that MBP has no significant sequence homology with other characterized proteins.
T8 1219-1411 Sentence denotes The basicity (pI 10.9) and hydrophobicity predicted from the MBP sequence are likely responsible for the observed affinity of this cytotoxic molecule for cell surfaces and some serum proteins.

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 48-53 OrganismTaxon denotes human 9606

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 54-64 Body_part denotes eosinophil http://purl.obolibrary.org/obo/CL_0017502
T2 253-263 Body_part denotes eosinophil http://purl.obolibrary.org/obo/CL_0017502

CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 54-64 Cell denotes eosinophil http://purl.obolibrary.org/obo/CL:0000771
T2 94-104 Cell denotes Eosinophil http://purl.obolibrary.org/obo/CL:0000771
T3 253-263 Cell denotes eosinophil http://purl.obolibrary.org/obo/CL:0000771