| Id |
Subject |
Object |
Predicate |
Lexical cue |
| TextSentencer_T1 |
0-96 |
Sentence |
denotes |
Synthesis of a close analog of the repeating unit of the antifreeze glycoproteins of polar fish. |
| TextSentencer_T2 |
97-397 |
Sentence |
denotes |
The protected glycopeptide N-(benzyloxycarbonyl)-L-alanyl-[O-(2,3,4,6-tetra-O-benzoyl-beta-D- galactopyranosyl)-(1----3)-O-(2,4,6-tri-O-benzyl-alpha-D-galactopyranosy l)- (1----3)]-L-threonyl-L-alanine 2,2,2-trichloroethyl ester was made by coupling the respective disaccharide and tripeptide blocks. |
| TextSentencer_T3 |
398-754 |
Sentence |
denotes |
The disaccharide block was generated by coupling tetra-O-benzoyl-alpha-D-galactopyranosyl bromide to allyl 2,4,6-tri-O-benzyl-alpha-D-galactopyranoside and converting the product into O-(2,3,4,6-tetra-O-benzoyl-beta-D-galactopyranosyl)-(1----3)-2,4,6-tri-O -benzyl - alpha-D-galactopyranosyl chloride via the 1-propenyl glycoside and the free (1-OH) sugar. |
| TextSentencer_T4 |
755-934 |
Sentence |
denotes |
Alternatively, the 1-propenyl intermediate was obtained directly by using 1-propenyl 2,4,6-tri-O-benzyl-alpha-D-galactopyranoside as the acceptor in the initial coupling reaction. |
| TextSentencer_T5 |
935-1169 |
Sentence |
denotes |
An efficient 3-step synthesis of 10 was accomplished by the dibutyltin oxide-assisted, selective crotylation of allyl alpha-D-galactopyranoside at O-3, followed by benzylation and treatment of the product with potassium tert-butoxide. |
| TextSentencer_T6 |
1170-1320 |
Sentence |
denotes |
The N-benzyloxycarbonyl (Z) and N-tert-butoxycarbonyl (Boc) 2,2,2-trichloroethyl esters of Thr-Ala and Ala-Thr-Ala were formed by sequential coupling. |
| TextSentencer_T7 |
1321-1546 |
Sentence |
denotes |
The silver triflate-promoted glycosylation of the Z-protected dipeptide and tripeptide by 2,3,4,6-tetra-O-benzyl-alpha-D-galactopyranosyl chloride, and of the tripeptide by 6, proceeded with excellent alpha-stereoselectivity. |
| TextSentencer_T8 |
1547-1657 |
Sentence |
denotes |
From the disaccharide tripeptide 21, the carboxyl-deprotected and fully deprotected derivatives were prepared. |
| T1 |
0-96 |
Sentence |
denotes |
Synthesis of a close analog of the repeating unit of the antifreeze glycoproteins of polar fish. |
| T2 |
97-397 |
Sentence |
denotes |
The protected glycopeptide N-(benzyloxycarbonyl)-L-alanyl-[O-(2,3,4,6-tetra-O-benzoyl-beta-D- galactopyranosyl)-(1----3)-O-(2,4,6-tri-O-benzyl-alpha-D-galactopyranosy l)- (1----3)]-L-threonyl-L-alanine 2,2,2-trichloroethyl ester was made by coupling the respective disaccharide and tripeptide blocks. |
| T3 |
398-754 |
Sentence |
denotes |
The disaccharide block was generated by coupling tetra-O-benzoyl-alpha-D-galactopyranosyl bromide to allyl 2,4,6-tri-O-benzyl-alpha-D-galactopyranoside and converting the product into O-(2,3,4,6-tetra-O-benzoyl-beta-D-galactopyranosyl)-(1----3)-2,4,6-tri-O -benzyl - alpha-D-galactopyranosyl chloride via the 1-propenyl glycoside and the free (1-OH) sugar. |
| T4 |
755-934 |
Sentence |
denotes |
Alternatively, the 1-propenyl intermediate was obtained directly by using 1-propenyl 2,4,6-tri-O-benzyl-alpha-D-galactopyranoside as the acceptor in the initial coupling reaction. |
| T5 |
935-1169 |
Sentence |
denotes |
An efficient 3-step synthesis of 10 was accomplished by the dibutyltin oxide-assisted, selective crotylation of allyl alpha-D-galactopyranoside at O-3, followed by benzylation and treatment of the product with potassium tert-butoxide. |
| T6 |
1170-1320 |
Sentence |
denotes |
The N-benzyloxycarbonyl (Z) and N-tert-butoxycarbonyl (Boc) 2,2,2-trichloroethyl esters of Thr-Ala and Ala-Thr-Ala were formed by sequential coupling. |
| T7 |
1321-1546 |
Sentence |
denotes |
The silver triflate-promoted glycosylation of the Z-protected dipeptide and tripeptide by 2,3,4,6-tetra-O-benzyl-alpha-D-galactopyranosyl chloride, and of the tripeptide by 6, proceeded with excellent alpha-stereoselectivity. |
| T8 |
1547-1657 |
Sentence |
denotes |
From the disaccharide tripeptide 21, the carboxyl-deprotected and fully deprotected derivatives were prepared. |