| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1 |
0-46 |
Sentence |
denotes |
Evaluation of a SARS-CoV-2 rapid antigen test: |
| T2 |
47-89 |
Sentence |
denotes |
Potential to help reduce community spread? |
| T3 |
90-101 |
Sentence |
denotes |
BACKGROUND: |
| T4 |
102-254 |
Sentence |
denotes |
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can spread from symptomatic patients with COVID-19, but also from asymptomatic individuals. |
| T5 |
255-378 |
Sentence |
denotes |
Therefore, robust surveillance and timely interventions are essential for the control of virus spread within the community. |
| T6 |
379-499 |
Sentence |
denotes |
In this regard the frequency of testing and speed of reporting, but not the test sensitivity alone, play a crucial role. |
| T7 |
500-511 |
Sentence |
denotes |
OBJECTIVES: |
| T8 |
512-697 |
Sentence |
denotes |
In order to reduce the costs and meet the expanding demands in real-time RT-PCR (rRT-PCR) testing for SARS-CoV-2, complementary assays, such as rapid antigen tests, have been developed. |
| T9 |
698-838 |
Sentence |
denotes |
Rigorous analysis under varying conditions is required to assess the clinical performance of these tests and to ensure reproducible results. |
| T10 |
839-847 |
Sentence |
denotes |
RESULTS: |
| T11 |
848-982 |
Sentence |
denotes |
We evaluated the sensitivity and specificity of a recently licensed rapid antigen test using 137 clinical samples in two institutions. |
| T12 |
983-1103 |
Sentence |
denotes |
Test sensitivity was between 88.2-89.6 % when applied to samples with viral loads typically seen in infectious patients. |
| T13 |
1104-1243 |
Sentence |
denotes |
Of 32 rRT-PCR positive samples, 19 demonstrated infectivity in cell culture, and 84 % of these samples were reactive with the antigen test. |
| T14 |
1244-1411 |
Sentence |
denotes |
Seven full-genome sequenced SARS-CoV-2 isolates and SARS-CoV-1 were detected with this antigen test, with no cross-reactivity against other common respiratory viruses. |
| T15 |
1412-1424 |
Sentence |
denotes |
CONCLUSIONS: |
| T16 |
1425-1549 |
Sentence |
denotes |
Numerous antigen tests are available for SARS-CoV-2 testing and their performance to detect infectious individuals may vary. |
| T17 |
1550-1683 |
Sentence |
denotes |
Head-to-head comparison along with cell culture testing for infectivity may prove useful to identify better performing antigen tests. |
| T18 |
1684-1766 |
Sentence |
denotes |
The antigen test analyzed in this study is easy-to-use, inexpensive, and scalable. |
| T19 |
1767-1862 |
Sentence |
denotes |
It can be helpful in monitoring infection trends and thus has potential to reduce transmission. |