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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T1 0-7 Body_part denotes Thyroid http://purl.org/sig/ont/fma/fma9603
T2 92-99 Body_part denotes thyroid http://purl.org/sig/ont/fma/fma9603
T3 100-104 Body_part denotes axis http://purl.org/sig/ont/fma/fma12520
T4 205-212 Body_part denotes thyroid http://purl.org/sig/ont/fma/fma9603
T5 295-302 Body_part denotes thyroid http://purl.org/sig/ont/fma/fma9603
T6 648-655 Body_part denotes thyroid http://purl.org/sig/ont/fma/fma9603
T7 1173-1180 Body_part denotes thyroid http://purl.org/sig/ont/fma/fma9603
T8 1604-1613 Body_part denotes thyroidal http://purl.org/sig/ont/fma/fma9603
T9 1671-1678 Body_part denotes thyroid http://purl.org/sig/ont/fma/fma9603

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 0-7 Body_part denotes Thyroid http://purl.obolibrary.org/obo/UBERON_0002046
T2 92-99 Body_part denotes thyroid http://purl.obolibrary.org/obo/UBERON_0002046
T3 205-212 Body_part denotes thyroid http://purl.obolibrary.org/obo/UBERON_0002046
T4 295-302 Body_part denotes thyroid http://purl.obolibrary.org/obo/UBERON_0002046
T5 648-655 Body_part denotes thyroid http://purl.obolibrary.org/obo/UBERON_0002046
T6 1173-1180 Body_part denotes thyroid http://purl.obolibrary.org/obo/UBERON_0002046
T7 1671-1678 Body_part denotes thyroid http://purl.obolibrary.org/obo/UBERON_0002046

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 42-50 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T2 76-84 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T3 171-185 Disease denotes thyrotoxicosis http://purl.obolibrary.org/obo/MONDO_0010138
T4 283-291 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T5 372-380 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T6 556-564 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T7 648-663 Disease denotes thyroid disease http://purl.obolibrary.org/obo/MONDO_0003240
T8 756-764 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T9 892-900 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T10 959-967 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T11 1016-1030 Disease denotes thyrotoxicosis http://purl.obolibrary.org/obo/MONDO_0010138
T12 1046-1054 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T13 1115-1123 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T14 1132-1140 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T15 1336-1344 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T16 1503-1511 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T17 1661-1669 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1 139-142 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T2 232-241 http://purl.obolibrary.org/obo/BFO_0000030 denotes OBJECTIVE
T3 590-592 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T4 1059-1060 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T5 1190-1195 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T6 1307-1308 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T7 1598-1599 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T8 1688-1693 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T1 0-7 Chemical denotes Thyroid http://purl.obolibrary.org/obo/CHEBI_9584
T2 390-396 Chemical denotes Cohort http://purl.obolibrary.org/obo/CHEBI_34935
T3 694-703 Chemical denotes thyroxine http://purl.obolibrary.org/obo/CHEBI_305790|http://purl.obolibrary.org/obo/CHEBI_30660
T5 713-716 Chemical denotes TSH http://purl.obolibrary.org/obo/CHEBI_137741|http://purl.obolibrary.org/obo/CHEBI_17842
T7 805-808 Chemical denotes TSH http://purl.obolibrary.org/obo/CHEBI_137741|http://purl.obolibrary.org/obo/CHEBI_17842
T9 1077-1080 Chemical denotes TSH http://purl.obolibrary.org/obo/CHEBI_137741|http://purl.obolibrary.org/obo/CHEBI_17842
T11 1217-1220 Chemical denotes TSH http://purl.obolibrary.org/obo/CHEBI_137741|http://purl.obolibrary.org/obo/CHEBI_17842
T13 1244-1247 Chemical denotes TSH http://purl.obolibrary.org/obo/CHEBI_137741|http://purl.obolibrary.org/obo/CHEBI_17842
T15 1359-1362 Chemical denotes TSH http://purl.obolibrary.org/obo/CHEBI_137741|http://purl.obolibrary.org/obo/CHEBI_17842
T17 1421-1424 Chemical denotes TSH http://purl.obolibrary.org/obo/CHEBI_137741|http://purl.obolibrary.org/obo/CHEBI_17842
T19 1570-1573 Chemical denotes TSH http://purl.obolibrary.org/obo/CHEBI_137741|http://purl.obolibrary.org/obo/CHEBI_17842

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
1 42-50 Disease denotes COVID-19 MESH:C000657245
29 76-84 Disease denotes COVID-19 MESH:C000657245
30 171-185 Disease denotes thyrotoxicosis MESH:D013971
31 283-291 Disease denotes COVID-19 MESH:C000657245
32 372-380 Disease denotes COVID-19 MESH:C000657245
33 418-430 Species denotes PARTICIPANTS Tax:9606
34 450-458 Species denotes patients Tax:9606
35 556-564 Disease denotes COVID-19 MESH:C000657245
36 648-663 Disease denotes thyroid disease MESH:D013959
37 694-703 Chemical denotes thyroxine MESH:D013974
38 738-746 Species denotes patients Tax:9606
39 756-764 Disease denotes COVID-19 MESH:C000657245
40 892-900 Disease denotes COVID-19 MESH:C000657245
41 926-934 Species denotes patients Tax:9606
42 959-967 Disease denotes COVID-19 MESH:C000657245
43 1016-1030 Disease denotes thyrotoxicosis MESH:D013971
44 1032-1040 Species denotes Patients Tax:9606
45 1046-1054 Disease denotes COVID-19 MESH:C000657245
46 1115-1123 Disease denotes COVID-19 MESH:C000657245
47 1132-1140 Disease denotes COVID-19 MESH:C000657245
48 1141-1149 Species denotes patients Tax:9606
49 1336-1344 Disease denotes COVID-19 MESH:C000657245
50 1345-1353 Species denotes patients Tax:9606
51 1489-1497 Species denotes patients Tax:9606
52 1503-1511 Disease denotes COVID-19 MESH:C000657245
53 1525-1537 Disease denotes euthyroidism MESH:D005067
54 1604-1630 Disease denotes thyroidal illness syndrome MESH:D013959
55 1661-1669 Disease denotes COVID-19 MESH:C000657245

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T1 0-51 Sentence denotes Thyroid function before, during and after COVID-19.
T2 52-60 Sentence denotes CONTEXT:
T3 61-122 Sentence denotes The effects of COVID-19 on the thyroid axis remain uncertain.
T4 123-231 Sentence denotes Recent evidence has been conflicting, with both thyrotoxicosis and suppression of thyroid function reported.
T5 232-242 Sentence denotes OBJECTIVE:
T6 243-381 Sentence denotes We aimed to detail the acute effects of COVID-19 on thyroid function and determine if these effects persisted upon recovery from COVID-19.
T7 382-389 Sentence denotes DESIGN:
T8 390-417 Sentence denotes Cohort observational study.
T9 418-443 Sentence denotes PARTICIPANTS AND SETTING:
T10 444-730 Sentence denotes Adult patients admitted to Imperial College Healthcare National Health Service Trust, London, UK with suspected COVID-19 between March 9 to April 22, 2020 were included, excluding those with pre-existing thyroid disease and those missing either free thyroxine (FT4) or TSH measurements.
T11 731-781 Sentence denotes Of 456 patients, 334 had COVID-19 and 122 did not.
T12 782-911 Sentence denotes MAIN OUTCOME MEASURES: TSH and FT4 measurements at admission, and where available, those taken in 2019 and at COVID-19 follow-up.
T13 912-920 Sentence denotes RESULTS:
T14 921-1031 Sentence denotes Most patients (86·6%) presenting with COVID-19 were euthyroid, with none presenting with overt thyrotoxicosis.
T15 1032-1124 Sentence denotes Patients with COVID-19 had a lower admission TSH and FT4 compared to those without COVID-19.
T16 1125-1303 Sentence denotes In the COVID-19 patients with matching baseline thyroid function tests from 2019 (n=185 for TSH and 104 for FT4), both TSH and FT4 were reduced at admission compared to baseline.
T17 1304-1470 Sentence denotes In a complete cases analysis of COVID-19 patients with TSH measurements at follow-up, admission and baseline (n=55), TSH was seen to recover to baseline at follow-up.
T18 1471-1483 Sentence denotes CONCLUSIONS:
T19 1484-1538 Sentence denotes Most patients with COVID-19 present with euthyroidism.
T20 1539-1631 Sentence denotes We observed mild reductions in TSH and FT4 in keeping with a non-thyroidal illness syndrome.
T21 1632-1728 Sentence denotes Furthermore, in survivors of COVID-19, thyroid function tests at follow-up returned to baseline.

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T1 648-663 Phenotype denotes thyroid disease http://purl.obolibrary.org/obo/HP_0000820