PubMed:33180877
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T1 | 94-99 | Body_part | denotes | chest | http://purl.org/sig/ont/fma/fma9576 |
| T2 | 172-187 | Body_part | denotes | neural networks | http://purl.org/sig/ont/fma/fma74616 |
| T3 | 915-920 | Body_part | denotes | chest | http://purl.org/sig/ont/fma/fma9576 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 94-99 | Body_part | denotes | chest | http://purl.obolibrary.org/obo/UBERON_0001443 |
| T2 | 915-920 | Body_part | denotes | chest | http://purl.obolibrary.org/obo/UBERON_0001443 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 72-80 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T2 | 863-887 | Disease | denotes | Coronavirus disease 2019 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T3 | 889-897 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T4 | 1120-1128 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T5 | 2084-2092 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 94-99 | http://www.ebi.ac.uk/efo/EFO_0000965 | denotes | chest |
| T2 | 321-326 | http://purl.obolibrary.org/obo/UBERON_0001456 | denotes | faces |
| T3 | 760-761 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T4 | 915-920 | http://www.ebi.ac.uk/efo/EFO_0000965 | denotes | chest |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T1 | 140-142 | Chemical | denotes | DL | http://purl.obolibrary.org/obo/CHEBI_68596 |
| T2 | 575-577 | Chemical | denotes | DL | http://purl.obolibrary.org/obo/CHEBI_68596 |
| T3 | 689-691 | Chemical | denotes | GT | http://purl.obolibrary.org/obo/CHEBI_73920 |
| T4 | 819-830 | Chemical | denotes | application | http://purl.obolibrary.org/obo/CHEBI_33232 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 59-67 | http://purl.obolibrary.org/obo/GO_0007612 | denotes | learning |
| T2 | 130-138 | http://purl.obolibrary.org/obo/GO_0007612 | denotes | learning |
| T3 | 255-261 | http://purl.obolibrary.org/obo/GO_0007601 | denotes | vision |
| T4 | 308-314 | http://purl.obolibrary.org/obo/GO_0007601 | denotes | vision |
| T5 | 525-533 | http://purl.obolibrary.org/obo/GO_0007612 | denotes | learning |
| T6 | 588-596 | http://purl.obolibrary.org/obo/GO_0007610 | denotes | behavior |
| T7 | 715-723 | http://purl.obolibrary.org/obo/GO_0007612 | denotes | learning |
| T8 | 1314-1322 | http://purl.obolibrary.org/obo/GO_0007612 | denotes | learning |
| T9 | 1410-1418 | http://purl.obolibrary.org/obo/GO_0007610 | denotes | behavior |
| T10 | 1498-1510 | http://purl.obolibrary.org/obo/GO_0051179 | denotes | localization |
| T11 | 1569-1581 | http://purl.obolibrary.org/obo/GO_0051179 | denotes | localization |
| T12 | 1740-1752 | http://purl.obolibrary.org/obo/GO_0051179 | denotes | localization |
| T13 | 2003-2015 | http://purl.obolibrary.org/obo/GO_0051179 | denotes | localization |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 1 | 72-80 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 6 | 863-887 | Disease | denotes | Coronavirus disease 2019 | MESH:C000657245 |
| 7 | 889-897 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 8 | 1120-1128 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 9 | 2084-2092 | Disease | denotes | COVID-19 | MESH:C000657245 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-112 | Sentence | denotes | Analyzing inter-reader variability affecting deep ensemble learning for COVID-19 detection in chest radiographs. |
| T2 | 113-268 | Sentence | denotes | Data-driven deep learning (DL) methods using convolutional neural networks (CNNs) demonstrate promising performance in natural image computer vision tasks. |
| T3 | 269-739 | Sentence | denotes | However, their use in medical computer vision tasks faces several limitations, viz., (i) adapting to visual characteristics that are unlike natural images; (ii) modeling random noise during training due to stochastic optimization and backpropagation-based learning strategy; (iii) challenges in explaining DL black-box behavior to support clinical decision-making; and (iv) inter-reader variability in the ground truth (GT) annotations affecting learning and evaluation. |
| T4 | 740-935 | Sentence | denotes | This study proposes a systematic approach to address these limitations through application to the pandemic-caused need for Coronavirus disease 2019 (COVID-19) detection using chest X-rays (CXRs). |
| T5 | 936-1669 | Sentence | denotes | Specifically, our contribution highlights significant benefits obtained through (i) pretraining specific to CXRs in transferring and fine-tuning the learned knowledge toward improving COVID-19 detection performance; (ii) using ensembles of the fine-tuned models to further improve performance over individual constituent models; (iii) performing statistical analyses at various learning stages for validating results; (iv) interpreting learned individual and ensemble model behavior through class-selective relevance mapping (CRM)-based region of interest (ROI) localization; and, (v) analyzing inter-reader variability and ensemble localization performance using Simultaneous Truth and Performance Level Estimation (STAPLE) methods. |
| T6 | 1670-1889 | Sentence | denotes | We find that ensemble approaches markedly improved classification and localization performance, and that inter-reader variability and performance level assessment helps guide algorithm design and parameter optimization. |
| T7 | 1890-2111 | Sentence | denotes | To the best of our knowledge, this is the first study to construct ensembles, perform ensemble-based disease ROI localization, and analyze inter-reader variability and algorithm performance for COVID-19 detection in CXRs. |