PubMed:33164997
Annnotations
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T1 | 262-278 | Body_part | denotes | epithelial cells | http://purl.org/sig/ont/fma/fma66768 |
T2 | 273-278 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T3 | 657-662 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T4 | 671-680 | Body_part | denotes | cytokines | http://purl.org/sig/ont/fma/fma84050 |
T5 | 700-706 | Body_part | denotes | tissue | http://purl.org/sig/ont/fma/fma9637 |
T6 | 714-730 | Body_part | denotes | epithelial cells | http://purl.org/sig/ont/fma/fma66768 |
T7 | 725-730 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T8 | 864-869 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T9 | 894-899 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T10 | 997-1007 | Body_part | denotes | (Th1) cell | http://purl.org/sig/ont/fma/fma84382 |
T11 | 1003-1007 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T12 | 1130-1139 | Body_part | denotes | cytokines | http://purl.org/sig/ont/fma/fma84050 |
T13 | 1149-1165 | Body_part | denotes | epithelial cells | http://purl.org/sig/ont/fma/fma66768 |
T14 | 1160-1165 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T15 | 1204-1220 | Body_part | denotes | epithelial cells | http://purl.org/sig/ont/fma/fma66768 |
T16 | 1215-1220 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T17 | 1301-1307 | Body_part | denotes | tissue | http://purl.org/sig/ont/fma/fma9637 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T1 | 700-706 | Body_part | denotes | tissue | http://purl.obolibrary.org/obo/UBERON_0000479 |
T2 | 1301-1307 | Body_part | denotes | tissue | http://purl.obolibrary.org/obo/UBERON_0000479 |
LitCovid-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T1 | 450-462 | Phenotype | denotes | nasal polyps | http://purl.obolibrary.org/obo/HP_0100582 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T1 | 50-58 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T2 | 79-103 | Disease | denotes | Coronavirus disease 2019 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T3 | 105-113 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T4 | 136-183 | Disease | denotes | severe acute respiratory syndrome coronavirus 2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T5 | 136-169 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
T6 | 185-193 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T7 | 305-313 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T8 | 316-325 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T9 | 422-444 | Disease | denotes | chronic rhinosinusitis | http://purl.obolibrary.org/obo/MONDO_0006031 |
T10 | 450-462 | Disease | denotes | nasal polyps | http://purl.obolibrary.org/obo/MONDO_0006314 |
T11 | 500-508 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T12 | 511-520 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T13 | 606-618 | Disease | denotes | inflammation | http://purl.obolibrary.org/obo/MONDO_0021166 |
T14 | 843-851 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T15 | 925-933 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T16 | 936-945 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T17 | 1279-1291 | Disease | denotes | inflammation | http://purl.obolibrary.org/obo/MONDO_0021166 |
T18 | 1333-1341 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T19 | 1344-1353 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T20 | 1436-1444 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 116-117 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T2 | 198-201 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T3 | 217-218 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T4 | 262-272 | http://purl.obolibrary.org/obo/CL_0000066 | denotes | epithelial |
T5 | 273-278 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T6 | 657-662 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T7 | 714-724 | http://purl.obolibrary.org/obo/CL_0000066 | denotes | epithelial |
T8 | 725-730 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T9 | 864-869 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T10 | 894-899 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T11 | 972-982 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activation |
T12 | 1003-1007 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T13 | 1149-1159 | http://purl.obolibrary.org/obo/CL_0000066 | denotes | epithelial |
T14 | 1160-1165 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T15 | 1204-1214 | http://purl.obolibrary.org/obo/CL_0000066 | denotes | epithelial |
T16 | 1215-1220 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T1 | 762-773 | Chemical | denotes | angiotensin | http://purl.obolibrary.org/obo/CHEBI_48433 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 606-618 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammation |
T2 | 1279-1291 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammation |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
1 | 50-58 | Disease | denotes | COVID-19 | MESH:C000657245 |
20 | 79-103 | Disease | denotes | Coronavirus disease 2019 | MESH:C000657245 |
21 | 105-113 | Disease | denotes | COVID-19 | MESH:C000657245 |
22 | 136-183 | Species | denotes | severe acute respiratory syndrome coronavirus 2 | Tax:2697049 |
23 | 185-195 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
24 | 310-325 | Disease | denotes | CoV-2 infection | MESH:C000657245 |
25 | 430-462 | Disease | denotes | rhinosinusitis with nasal polyps | MESH:D009298 |
26 | 500-520 | Disease | denotes | SARS-CoV-2 infection | MESH:C000657245 |
27 | 606-618 | Disease | denotes | inflammation | MESH:D007249 |
28 | 762-793 | Gene | denotes | angiotensin-converting enzyme 2 | Gene:59272 |
29 | 795-799 | Gene | denotes | ACE2 | Gene:59272 |
30 | 843-853 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
31 | 925-945 | Disease | denotes | SARS-CoV-2 infection | MESH:C000657245 |
32 | 1055-1059 | Gene | denotes | ACE2 | Gene:59272 |
33 | 1190-1194 | Gene | denotes | ACE2 | Gene:59272 |
34 | 1279-1291 | Disease | denotes | inflammation | MESH:D007249 |
35 | 1333-1353 | Disease | denotes | SARS-CoV-2 infection | MESH:C000657245 |
36 | 1370-1374 | Gene | denotes | ACE2 | Gene:59272 |
37 | 1436-1444 | Disease | denotes | COVID-19 | MESH:C000657245 |
Inflammaging
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-59 | Sentence | denotes | Inflammatory endotypes of CRSwNP and responses to COVID-19. |
T2 | 60-78 | Sentence | denotes | PURPOSE OF REVIEW: |
T3 | 79-255 | Sentence | denotes | Coronavirus disease 2019 (COVID-19), a disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has quickly become a great public health hazard globally. |
T4 | 256-342 | Sentence | denotes | Nasal epithelial cells are an important site for SARS-CoV-2 infection and replication. |
T5 | 343-521 | Sentence | denotes | The purpose of this review is to summarize recent findings on the endotypes of chronic rhinosinusitis with nasal polyps (CRSwNP) and the potential impact of SARS-CoV-2 infection. |
T6 | 522-538 | Sentence | denotes | RECENT FINDINGS: |
T7 | 539-707 | Sentence | denotes | Endotypes of CRSwNP are characterized by type 1, type 2 and type 3 inflammation according to patterns of inflammatory cells and the cytokines expressed in nasal tissue. |
T8 | 708-924 | Sentence | denotes | Nasal epithelial cells show the highest expression of angiotensin-converting enzyme 2 (ACE2), the receptor for attachment and entry of SARS-CoV-2 into host cells, among all investigated cells in the respiratory tree. |
T9 | 925-1018 | Sentence | denotes | SARS-CoV-2 infection likely leads to increased activation of T-helper-1 (Th1) cell responses. |
T10 | 1019-1166 | Sentence | denotes | Recent studies further suggest that ACE2 may be upregulated by type 1 and downregulated by type 2 inflammatory cytokines in nasal epithelial cells. |
T11 | 1167-1175 | Sentence | denotes | SUMMARY: |
T12 | 1176-1271 | Sentence | denotes | Expression of ACE2 in nasal epithelial cells is influenced by inflammatory endotypes of CRSwNP. |
T13 | 1272-1386 | Sentence | denotes | Type 1 inflammation in nasal tissue may increase the risk of SARS-CoV-2 infection by upregulating ACE2 expression. |
T14 | 1387-1462 | Sentence | denotes | However, clinical association between CRSwNP and COVID-19 is still unclear. |
T1 | 0-59 | Sentence | denotes | Inflammatory endotypes of CRSwNP and responses to COVID-19. |
T2 | 60-78 | Sentence | denotes | PURPOSE OF REVIEW: |
T3 | 79-255 | Sentence | denotes | Coronavirus disease 2019 (COVID-19), a disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has quickly become a great public health hazard globally. |
T4 | 256-342 | Sentence | denotes | Nasal epithelial cells are an important site for SARS-CoV-2 infection and replication. |
T5 | 343-521 | Sentence | denotes | The purpose of this review is to summarize recent findings on the endotypes of chronic rhinosinusitis with nasal polyps (CRSwNP) and the potential impact of SARS-CoV-2 infection. |
T6 | 522-538 | Sentence | denotes | RECENT FINDINGS: |
T7 | 539-707 | Sentence | denotes | Endotypes of CRSwNP are characterized by type 1, type 2 and type 3 inflammation according to patterns of inflammatory cells and the cytokines expressed in nasal tissue. |
T8 | 708-924 | Sentence | denotes | Nasal epithelial cells show the highest expression of angiotensin-converting enzyme 2 (ACE2), the receptor for attachment and entry of SARS-CoV-2 into host cells, among all investigated cells in the respiratory tree. |
T9 | 925-1018 | Sentence | denotes | SARS-CoV-2 infection likely leads to increased activation of T-helper-1 (Th1) cell responses. |
T10 | 1019-1166 | Sentence | denotes | Recent studies further suggest that ACE2 may be upregulated by type 1 and downregulated by type 2 inflammatory cytokines in nasal epithelial cells. |
T11 | 1167-1175 | Sentence | denotes | SUMMARY: |
T12 | 1176-1271 | Sentence | denotes | Expression of ACE2 in nasal epithelial cells is influenced by inflammatory endotypes of CRSwNP. |
T13 | 1272-1386 | Sentence | denotes | Type 1 inflammation in nasal tissue may increase the risk of SARS-CoV-2 infection by upregulating ACE2 expression. |
T14 | 1387-1462 | Sentence | denotes | However, clinical association between CRSwNP and COVID-19 is still unclear. |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-59 | Sentence | denotes | Inflammatory endotypes of CRSwNP and responses to COVID-19. |
T2 | 60-78 | Sentence | denotes | PURPOSE OF REVIEW: |
T3 | 79-255 | Sentence | denotes | Coronavirus disease 2019 (COVID-19), a disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has quickly become a great public health hazard globally. |
T4 | 256-342 | Sentence | denotes | Nasal epithelial cells are an important site for SARS-CoV-2 infection and replication. |
T5 | 343-521 | Sentence | denotes | The purpose of this review is to summarize recent findings on the endotypes of chronic rhinosinusitis with nasal polyps (CRSwNP) and the potential impact of SARS-CoV-2 infection. |
T6 | 522-538 | Sentence | denotes | RECENT FINDINGS: |
T7 | 539-707 | Sentence | denotes | Endotypes of CRSwNP are characterized by type 1, type 2 and type 3 inflammation according to patterns of inflammatory cells and the cytokines expressed in nasal tissue. |
T8 | 708-924 | Sentence | denotes | Nasal epithelial cells show the highest expression of angiotensin-converting enzyme 2 (ACE2), the receptor for attachment and entry of SARS-CoV-2 into host cells, among all investigated cells in the respiratory tree. |
T9 | 925-1018 | Sentence | denotes | SARS-CoV-2 infection likely leads to increased activation of T-helper-1 (Th1) cell responses. |
T10 | 1019-1166 | Sentence | denotes | Recent studies further suggest that ACE2 may be upregulated by type 1 and downregulated by type 2 inflammatory cytokines in nasal epithelial cells. |
T11 | 1167-1175 | Sentence | denotes | SUMMARY: |
T12 | 1176-1271 | Sentence | denotes | Expression of ACE2 in nasal epithelial cells is influenced by inflammatory endotypes of CRSwNP. |
T13 | 1272-1386 | Sentence | denotes | Type 1 inflammation in nasal tissue may increase the risk of SARS-CoV-2 infection by upregulating ACE2 expression. |
T14 | 1387-1462 | Sentence | denotes | However, clinical association between CRSwNP and COVID-19 is still unclear. |
LitCovid_AGAC_only
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
p284353s19 | 1370-1374 | Gene | denotes | ACE2 |
p284353s20 | 1375-1385 | MPA | denotes | expression |