> top > docs > PubMed:33163956 > annotations

PubMed:33163956 JSONTXT

Annnotations TAB JSON ListView MergeView

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T1 173-178 Body_part denotes brain http://purl.org/sig/ont/fma/fma50801
T2 316-324 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T3 348-361 Body_part denotes interleukin 6 http://purl.org/sig/ont/fma/fma264829
T4 348-359 Body_part denotes interleukin http://purl.org/sig/ont/fma/fma86578
T5 596-611 Body_part denotes immunoglobulins http://purl.org/sig/ont/fma/fma62871
T6 616-624 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T7 723-729 Body_part denotes mental http://purl.org/sig/ont/fma/fma264279
T8 781-786 Body_part denotes brain http://purl.org/sig/ont/fma/fma50801
T9 850-855 Body_part denotes brain http://purl.org/sig/ont/fma/fma50801
T10 897-912 Body_part denotes frontal regions http://purl.org/sig/ont/fma/fma61824
T11 914-928 Body_part denotes right thalamus http://purl.org/sig/ont/fma/fma258714
T12 940-954 Body_part denotes temporal lobes http://purl.org/sig/ont/fma/fma61825
T13 959-977 Body_part denotes cerebral peduncles http://purl.org/sig/ont/fma/fma62394
T14 1015-1034 Body_part denotes Cerebrospinal fluid http://purl.org/sig/ont/fma/fma20935
T15 1036-1039 Body_part denotes CSF http://purl.org/sig/ont/fma/fma20935
T16 1050-1059 Body_part denotes leukocyte http://purl.org/sig/ont/fma/fma62852
T17 1080-1091 Body_part denotes lymphocytes http://purl.org/sig/ont/fma/fma62863
T18 1094-1101 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T19 1126-1133 Body_part denotes glucose http://purl.org/sig/ont/fma/fma82743
T20 1260-1263 Body_part denotes CSF http://purl.org/sig/ont/fma/fma20935
T21 1299-1304 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T22 1324-1334 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T23 1465-1480 Body_part denotes immunoglobulins http://purl.org/sig/ont/fma/fma62871
T24 1485-1493 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 173-178 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955
T2 781-786 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955
T3 850-855 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955
T4 940-954 Body_part denotes temporal lobes http://purl.obolibrary.org/obo/UBERON_0001871
T5 959-977 Body_part denotes cerebral peduncles http://purl.obolibrary.org/obo/UBERON_0002623
T6 1015-1034 Body_part denotes Cerebrospinal fluid http://purl.obolibrary.org/obo/UBERON_0001359
T7 1299-1304 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 0-8 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T2 20-32 Disease denotes encephalitis http://purl.obolibrary.org/obo/MONDO_0019956
T3 98-110 Disease denotes encephalitis http://purl.obolibrary.org/obo/MONDO_0019956
T4 134-148 Disease denotes viral diseases http://purl.obolibrary.org/obo/MONDO_0005108
T5 156-165 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T6 219-243 Disease denotes coronavirus disease 2019 http://purl.obolibrary.org/obo/MONDO_0100096
T7 245-253 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T8 409-421 Disease denotes encephalitis http://purl.obolibrary.org/obo/MONDO_0019956
T9 451-498 Disease denotes severe acute respiratory syndrome coronavirus-2 http://purl.obolibrary.org/obo/MONDO_0100096
T10 451-484 Disease denotes severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T11 500-508 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T12 512-521 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T13 1147-1155 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T14 1593-1610 Disease denotes encephalomyelitis http://purl.obolibrary.org/obo/MONDO_0005156
T15 1764-1772 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T16 1791-1803 Disease denotes encephalitis http://purl.obolibrary.org/obo/MONDO_0019956
T17 1843-1860 Disease denotes encephalomyelitis http://purl.obolibrary.org/obo/MONDO_0005156

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1 173-178 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T2 173-178 http://www.ebi.ac.uk/efo/EFO_0000302 denotes brain
T3 274-275 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T4 348-361 http://purl.obolibrary.org/obo/PR_000001393 denotes interleukin 6
T5 380-381 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T6 648-649 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T7 779-780 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T8 781-786 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T9 781-786 http://www.ebi.ac.uk/efo/EFO_0000302 denotes brain
T10 850-855 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T11 850-855 http://www.ebi.ac.uk/efo/EFO_0000302 denotes brain
T12 1048-1049 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T13 1299-1304 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T14 1299-1304 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T15 1305-1310 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T16 1389-1390 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T17 1629-1630 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T1 363-365 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T3 1094-1101 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T4 1126-1133 Chemical denotes glucose http://purl.obolibrary.org/obo/CHEBI_17234|http://purl.obolibrary.org/obo/CHEBI_4167
T6 1364-1366 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T8 1508-1519 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T9 1524-1526 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T11 1538-1548 Chemical denotes antagonist http://purl.obolibrary.org/obo/CHEBI_48706

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T1 289-310 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammatory response
T2 1206-1219 http://purl.obolibrary.org/obo/GO_0003968 denotes transcriptase
T3 1206-1219 http://purl.obolibrary.org/obo/GO_0003899 denotes transcriptase
T4 1697-1718 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammatory response

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
2 0-8 Disease denotes COVID-19 MESH:C000657245
3 20-32 Disease denotes encephalitis MESH:D004660
28 98-110 Disease denotes encephalitis MESH:D004660
29 134-148 Disease denotes viral diseases MESH:D001102
30 156-178 Disease denotes infection of the brain MESH:D007239
31 213-238 Disease denotes novel coronavirus disease MESH:C000657245
32 245-253 Disease denotes COVID-19 MESH:C000657245
33 348-361 Gene denotes interleukin 6 Gene:3569
34 363-367 Gene denotes IL-6 Gene:3569
35 403-421 Disease denotes acute encephalitis MESH:D000071072
36 451-498 Species denotes severe acute respiratory syndrome coronavirus-2 Tax:2697049
37 500-510 Species denotes SARS-CoV-2 Tax:2697049
38 512-521 Disease denotes infection MESH:D007239
39 723-744 Disease denotes mental disorientation MESH:D003221
40 759-764 Disease denotes fever MESH:D005334
41 769-777 Disease denotes headache MESH:D006261
42 1126-1133 Chemical denotes glucose MESH:D005947
43 1147-1157 Species denotes SARS-CoV-2 Tax:2697049
44 1364-1368 Gene denotes IL-6 Gene:3569
45 1508-1519 Chemical denotes tocilizumab MESH:C502936
46 1524-1528 Gene denotes IL-6 Gene:3569
47 1579-1610 Disease denotes demyelinating encephalomyelitis MESH:D003711
48 1616-1623 Species denotes patient Tax:9606
49 1764-1772 Disease denotes COVID-19 MESH:C000657245
50 1791-1812 Disease denotes encephalitis syndrome MESH:D004660
51 1823-1860 Disease denotes acute demyelinating encephalomyelitis MESH:D004684

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T1 0-79 Sentence denotes COVID-19-associated encephalitis successfully treated with combination therapy.
T2 80-91 Sentence denotes Background:
T3 92-205 Sentence denotes Acute encephalitis can occur in different viral diseases due to infection of the brain or by an immune mechanism.
T4 206-369 Sentence denotes Severe novel coronavirus disease 2019 (COVID-19) is associated with a major immune inflammatory response with cytokine upregulation including interleukin 6 (IL-6).
T5 370-634 Sentence denotes We report a case presenting with acute encephalitis that was diagnosed as having severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection with hyperinflammatory systemic response and recovered after therapy with immunoglobulins and cytokine blockade.
T6 635-647 Sentence denotes Case report:
T7 648-778 Sentence denotes A 39-year-old-man was brought to the Emergency Department with drowsiness, mental disorientation, intermittent fever and headache.
T8 779-1014 Sentence denotes A brain magnetic resonance imaging showed extensive involvement of the brain including cortical and subcortical right frontal regions, right thalamus, bilateral temporal lobes and cerebral peduncles, with no leptomeningeal enhancement.
T9 1015-1146 Sentence denotes Cerebrospinal fluid (CSF) showed a leukocyte count of 20/µL (90% lymphocytes), protein level of 198 mg/dL, and glucose of 48 mg/dL.
T10 1147-1264 Sentence denotes SARS-CoV-2 was detected in nasopharyngeal swabs by reverse-transcriptase-PCR (RT-PCR) but it was negative in the CSF.
T11 1265-1381 Sentence denotes Remarkable laboratory findings in blood tests included low lymphocyte count and elevated ferritin, IL-6 and D-dimer.
T12 1382-1452 Sentence denotes He had a complicated clinical course requiring mechanical ventilation.
T13 1453-1611 Sentence denotes Intravenous immunoglobulins and cytokine blockade with tocilizumab, an IL-6 receptor antagonist, were added considering acute demyelinating encephalomyelitis.
T14 1612-1719 Sentence denotes The patient made a full recovery, suggesting that it could have been related to host inflammatory response.
T15 1720-1731 Sentence denotes Conclusion:
T16 1732-1910 Sentence denotes This case report indicates that COVID-19 may present as an encephalitis syndrome mimicking acute demyelinating encephalomyelitis that could be amenable to therapeutic modulation.

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T1 20-32 Phenotype denotes encephalitis http://purl.obolibrary.org/obo/HP_0002383
T2 98-110 Phenotype denotes encephalitis http://purl.obolibrary.org/obo/HP_0002383
T3 409-421 Phenotype denotes encephalitis http://purl.obolibrary.org/obo/HP_0002383
T4 711-721 Phenotype denotes drowsiness http://purl.obolibrary.org/obo/HP_0002329
T5 723-744 Phenotype denotes mental disorientation http://purl.obolibrary.org/obo/HP_0001289
T6 746-764 Phenotype denotes intermittent fever http://purl.obolibrary.org/obo/HP_0001954
T7 769-777 Phenotype denotes headache http://purl.obolibrary.org/obo/HP_0002315
T8 987-1013 Phenotype denotes leptomeningeal enhancement http://purl.obolibrary.org/obo/HP_0032070
T9 1579-1592 Phenotype denotes demyelinating http://purl.obolibrary.org/obo/HP_0011096
T10 1791-1803 Phenotype denotes encephalitis http://purl.obolibrary.org/obo/HP_0002383
T11 1829-1842 Phenotype denotes demyelinating http://purl.obolibrary.org/obo/HP_0011096

Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-79 Sentence denotes COVID-19-associated encephalitis successfully treated with combination therapy.
T2 80-91 Sentence denotes Background:
T3 92-205 Sentence denotes Acute encephalitis can occur in different viral diseases due to infection of the brain or by an immune mechanism.
T4 206-369 Sentence denotes Severe novel coronavirus disease 2019 (COVID-19) is associated with a major immune inflammatory response with cytokine upregulation including interleukin 6 (IL-6).
T5 370-634 Sentence denotes We report a case presenting with acute encephalitis that was diagnosed as having severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection with hyperinflammatory systemic response and recovered after therapy with immunoglobulins and cytokine blockade.
T6 635-647 Sentence denotes Case report:
T7 648-778 Sentence denotes A 39-year-old-man was brought to the Emergency Department with drowsiness, mental disorientation, intermittent fever and headache.
T8 779-1014 Sentence denotes A brain magnetic resonance imaging showed extensive involvement of the brain including cortical and subcortical right frontal regions, right thalamus, bilateral temporal lobes and cerebral peduncles, with no leptomeningeal enhancement.
T9 1015-1146 Sentence denotes Cerebrospinal fluid (CSF) showed a leukocyte count of 20/µL (90% lymphocytes), protein level of 198 mg/dL, and glucose of 48 mg/dL.
T10 1147-1264 Sentence denotes SARS-CoV-2 was detected in nasopharyngeal swabs by reverse-transcriptase-PCR (RT-PCR) but it was negative in the CSF.
T11 1265-1381 Sentence denotes Remarkable laboratory findings in blood tests included low lymphocyte count and elevated ferritin, IL-6 and D-dimer.
T12 1382-1452 Sentence denotes He had a complicated clinical course requiring mechanical ventilation.
T13 1453-1611 Sentence denotes Intravenous immunoglobulins and cytokine blockade with tocilizumab, an IL-6 receptor antagonist, were added considering acute demyelinating encephalomyelitis.
T14 1612-1719 Sentence denotes The patient made a full recovery, suggesting that it could have been related to host inflammatory response.
T15 1720-1731 Sentence denotes Conclusion:
T16 1732-1910 Sentence denotes This case report indicates that COVID-19 may present as an encephalitis syndrome mimicking acute demyelinating encephalomyelitis that could be amenable to therapeutic modulation.
T1 0-79 Sentence denotes COVID-19-associated encephalitis successfully treated with combination therapy.
T2 80-91 Sentence denotes Background:
T3 92-205 Sentence denotes Acute encephalitis can occur in different viral diseases due to infection of the brain or by an immune mechanism.
T4 206-369 Sentence denotes Severe novel coronavirus disease 2019 (COVID-19) is associated with a major immune inflammatory response with cytokine upregulation including interleukin 6 (IL-6).
T5 370-634 Sentence denotes We report a case presenting with acute encephalitis that was diagnosed as having severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection with hyperinflammatory systemic response and recovered after therapy with immunoglobulins and cytokine blockade.
T6 635-647 Sentence denotes Case report:
T7 648-778 Sentence denotes A 39-year-old-man was brought to the Emergency Department with drowsiness, mental disorientation, intermittent fever and headache.
T8 779-1014 Sentence denotes A brain magnetic resonance imaging showed extensive involvement of the brain including cortical and subcortical right frontal regions, right thalamus, bilateral temporal lobes and cerebral peduncles, with no leptomeningeal enhancement.
T9 1015-1146 Sentence denotes Cerebrospinal fluid (CSF) showed a leukocyte count of 20/µL (90% lymphocytes), protein level of 198 mg/dL, and glucose of 48 mg/dL.
T10 1147-1264 Sentence denotes SARS-CoV-2 was detected in nasopharyngeal swabs by reverse-transcriptase-PCR (RT-PCR) but it was negative in the CSF.
T11 1265-1381 Sentence denotes Remarkable laboratory findings in blood tests included low lymphocyte count and elevated ferritin, IL-6 and D-dimer.
T12 1382-1452 Sentence denotes He had a complicated clinical course requiring mechanical ventilation.
T13 1453-1611 Sentence denotes Intravenous immunoglobulins and cytokine blockade with tocilizumab, an IL-6 receptor antagonist, were added considering acute demyelinating encephalomyelitis.
T14 1612-1719 Sentence denotes The patient made a full recovery, suggesting that it could have been related to host inflammatory response.
T15 1720-1731 Sentence denotes Conclusion:
T16 1732-1910 Sentence denotes This case report indicates that COVID-19 may present as an encephalitis syndrome mimicking acute demyelinating encephalomyelitis that could be amenable to therapeutic modulation.