PubMed:33123081
Annnotations
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T1 | 678-682 | Body_part | denotes | head | http://purl.org/sig/ont/fma/fma7154 |
T2 | 834-838 | Body_part | denotes | eyes | http://purl.org/sig/ont/fma/fma54448 |
T3 | 957-979 | Body_part | denotes | acetylcholine receptor | http://purl.org/sig/ont/fma/fma67251 |
T4 | 1060-1070 | Body_part | denotes | Antibodies | http://purl.org/sig/ont/fma/fma62871 |
T5 | 1072-1075 | Body_part | denotes | IgA | http://purl.org/sig/ont/fma/fma62874 |
T6 | 1076-1079 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
T7 | 1187-1192 | Body_part | denotes | serum | http://purl.org/sig/ont/fma/fma63083 |
T8 | 1343-1358 | Body_part | denotes | immunoglobulins | http://purl.org/sig/ont/fma/fma62871 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T1 | 678-682 | Body_part | denotes | head | http://purl.obolibrary.org/obo/UBERON_0000033 |
T2 | 1187-1192 | Body_part | denotes | serum | http://purl.obolibrary.org/obo/UBERON_0001977 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T1 | 24-41 | Disease | denotes | Myasthenia Gravis | http://purl.obolibrary.org/obo/MONDO_0009688 |
T2 | 47-55 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T3 | 141-158 | Disease | denotes | myasthenia gravis | http://purl.obolibrary.org/obo/MONDO_0009688 |
T4 | 165-173 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T5 | 209-216 | Disease | denotes | anosmia | http://purl.obolibrary.org/obo/MONDO_0010528 |
T6 | 582-588 | Disease | denotes | ptosis | http://purl.obolibrary.org/obo/MONDO_0000728 |
T7 | 713-720 | Disease | denotes | anosmia | http://purl.obolibrary.org/obo/MONDO_0010528 |
T8 | 1041-1058 | Disease | denotes | myasthenia gravis | http://purl.obolibrary.org/obo/MONDO_0009688 |
T9 | 1089-1097 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T10 | 1244-1254 | Disease | denotes | infectious | http://purl.obolibrary.org/obo/MONDO_0005550 |
T11 | 1450-1467 | Disease | denotes | myasthenia gravis | http://purl.obolibrary.org/obo/MONDO_0009688 |
T12 | 1502-1510 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 45-46 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T2 | 65-74 | http://purl.obolibrary.org/obo/BFO_0000030 | denotes | Objective |
T3 | 98-99 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T4 | 456-462 | http://purl.obolibrary.org/obo/UBERON_0003100 | denotes | female |
T5 | 668-673 | http://www.ebi.ac.uk/efo/EFO_0000876 | denotes | limbs |
T6 | 678-682 | http://purl.obolibrary.org/obo/UBERON_0000033 | denotes | head |
T7 | 678-682 | http://www.ebi.ac.uk/efo/EFO_0000964 | denotes | head |
T8 | 834-838 | http://www.ebi.ac.uk/efo/EFO_0000827 | denotes | eyes |
T9 | 901-902 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T10 | 912-916 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | test |
T11 | 1134-1139 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | tests |
T12 | 1500-1501 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T1 | 922-942 | Chemical | denotes | edrophonium chloride | http://purl.obolibrary.org/obo/CHEBI_4759 |
T2 | 922-933 | Chemical | denotes | edrophonium | http://purl.obolibrary.org/obo/CHEBI_251408 |
T3 | 934-942 | Chemical | denotes | chloride | http://purl.obolibrary.org/obo/CHEBI_17996 |
T4 | 957-970 | Chemical | denotes | acetylcholine | http://purl.obolibrary.org/obo/CHEBI_15355 |
LitCovid-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T1 | 24-34 | Phenotype | denotes | Myasthenia | http://purl.obolibrary.org/obo/HP_0003473 |
T2 | 141-151 | Phenotype | denotes | myasthenia | http://purl.obolibrary.org/obo/HP_0003473 |
T3 | 209-216 | Phenotype | denotes | anosmia | http://purl.obolibrary.org/obo/HP_0000458 |
T4 | 217-224 | Phenotype | denotes | ageusia | http://purl.obolibrary.org/obo/HP_0041051 |
T5 | 515-528 | Phenotype | denotes | double vision | http://purl.obolibrary.org/obo/HP_0000651 |
T6 | 582-588 | Phenotype | denotes | ptosis | http://purl.obolibrary.org/obo/HP_0000508 |
T7 | 691-696 | Phenotype | denotes | fever | http://purl.obolibrary.org/obo/HP_0001945 |
T8 | 713-720 | Phenotype | denotes | anosmia | http://purl.obolibrary.org/obo/HP_0000458 |
T9 | 721-728 | Phenotype | denotes | ageusia | http://purl.obolibrary.org/obo/HP_0041051 |
T10 | 828-833 | Phenotype | denotes | tired | http://purl.obolibrary.org/obo/HP_0012378 |
T11 | 856-869 | Phenotype | denotes | double vision | http://purl.obolibrary.org/obo/HP_0000651 |
T12 | 1041-1051 | Phenotype | denotes | myasthenia | http://purl.obolibrary.org/obo/HP_0003473 |
T13 | 1450-1460 | Phenotype | denotes | myasthenia | http://purl.obolibrary.org/obo/HP_0003473 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 522-528 | http://purl.obolibrary.org/obo/GO_0007601 | denotes | vision |
T2 | 863-869 | http://purl.obolibrary.org/obo/GO_0007601 | denotes | vision |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
3 | 24-41 | Disease | denotes | Myasthenia Gravis | MESH:D009157 |
4 | 47-55 | Disease | denotes | COVID-19 | MESH:C000657245 |
5 | 56-63 | Species | denotes | Patient | Tax:9606 |
31 | 106-111 | Species | denotes | woman | Tax:9606 |
32 | 141-158 | Disease | denotes | myasthenia gravis | MESH:D009157 |
33 | 165-173 | Disease | denotes | COVID-19 | MESH:C000657245 |
34 | 184-204 | Disease | denotes | respiratory symptoms | MESH:D012818 |
35 | 209-224 | Disease | denotes | anosmia/ageusia | MESH:D000370 |
36 | 291-298 | Species | denotes | Patient | Tax:9606 |
37 | 422-429 | Species | denotes | patient | Tax:9606 |
38 | 463-470 | Species | denotes | patient | Tax:9606 |
39 | 582-588 | Disease | denotes | ptosis | MESH:C564553 |
40 | 639-659 | Disease | denotes | respiratory symptoms | MESH:D012818 |
41 | 691-696 | Disease | denotes | fever | MESH:D005334 |
42 | 713-728 | Disease | denotes | anosmia/ageusia | MESH:D000370 |
43 | 799-806 | Species | denotes | patient | Tax:9606 |
44 | 828-838 | Disease | denotes | tired eyes | MESH:C537575 |
45 | 922-942 | Chemical | denotes | edrophonium chloride | MESH:D004491 |
46 | 957-970 | Chemical | denotes | acetylcholine | MESH:D000109 |
47 | 1041-1058 | Disease | denotes | myasthenia gravis | MESH:D009157 |
48 | 1089-1099 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
49 | 1218-1229 | Species | denotes | coronavirus | Tax:11118 |
50 | 1268-1275 | Species | denotes | patient | Tax:9606 |
51 | 1281-1300 | Disease | denotes | myasthenic syndrome | MESH:D020294 |
52 | 1368-1382 | Chemical | denotes | pyridostigmine | MESH:D011729 |
53 | 1450-1467 | Disease | denotes | myasthenia gravis | MESH:D009157 |
54 | 1502-1510 | Disease | denotes | COVID-19 | MESH:C000657245 |
55 | 1511-1518 | Species | denotes | patient | Tax:9606 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-64 | Sentence | denotes | Postinfectious Onset of Myasthenia Gravis in a COVID-19 Patient. |
T2 | 65-75 | Sentence | denotes | Objective: |
T3 | 76-281 | Sentence | denotes | We report the case of a young woman with postinfectious onset of myasthenia gravis after COVID-19 with mild respiratory symptoms and anosmia/ageusia 1 month before admission to our neurological department. |
T4 | 282-290 | Sentence | denotes | Methods: |
T5 | 291-374 | Sentence | denotes | Patient data were derived from medical records of Hannover Medical School, Germany. |
T6 | 375-430 | Sentence | denotes | Written informed consent was obtained from the patient. |
T7 | 431-439 | Sentence | denotes | Results: |
T8 | 440-589 | Sentence | denotes | The 21-year-old female patient presented with subacute, vertically shifted double vision evoked by right sided partial oculomotor paresis and ptosis. |
T9 | 590-729 | Sentence | denotes | About 4 weeks earlier she had suffered from mild respiratory symptoms, aching limbs and head without fever, accompanied by anosmia/ageusia. |
T10 | 730-870 | Sentence | denotes | During the persistence of the latter symptoms for around 10 days the patient had already noticed "tired eyes" and fluctuating double vision. |
T11 | 871-1059 | Sentence | denotes | Clinical assessment including a positive test with edrophonium chloride and increased acetylcholine receptor antibodies related the ocular manifestation etiologically to myasthenia gravis. |
T12 | 1060-1276 | Sentence | denotes | Antibodies (IgA/IgG) against SARS-CoV-2 using three different serological tests (Abbott, DiaSorin, Euroimmun) were detected in serum suggesting this specific coronavirus as previously infectious agent in our patient. |
T13 | 1277-1383 | Sentence | denotes | The myasthenic syndrome was treated successfully with intravenous immunoglobulins and oral pyridostigmine. |
T14 | 1384-1395 | Sentence | denotes | Conclusion: |
T15 | 1396-1519 | Sentence | denotes | This is the first case presentation of postinfectious myasthenia gravis as neurological complication in a COVID-19 patient. |