> top > docs > PubMed:33116032 > annotations

PubMed:33116032 JSONTXT

Annnotations TAB JSON ListView MergeView

LitCovid_Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 423-430 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T2 423-430 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin
T3 521-528 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T4 521-528 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin
T5 1263-1270 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T6 1263-1270 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin
T7 1630-1637 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T8 1630-1637 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T1 423-430 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839
T2 521-528 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839
T3 948-954 Body_part denotes Plasma http://purl.org/sig/ont/fma/fma62970
T4 1014-1030 Body_part denotes endothelial cell http://purl.org/sig/ont/fma/fma66772
T5 1026-1030 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T6 1071-1075 Body_part denotes hand http://purl.org/sig/ont/fma/fma9712
T7 1077-1083 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T8 1263-1270 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839
T9 1630-1637 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 1071-1075 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 16-24 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T2 66-98 Disease denotes Acquired von Willebrand Syndrome http://purl.obolibrary.org/obo/MONDO_0020460
T3 121-129 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T4 171-183 Disease denotes coagulopathy http://purl.obolibrary.org/obo/MONDO_0001531
T5 194-204 Disease denotes thrombosis http://purl.obolibrary.org/obo/MONDO_0000831
T6 206-214 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T7 215-224 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T8 244-279 Disease denotes acute respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0006502
T9 250-279 Disease denotes respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0009971
T10 348-358 Disease denotes thrombosis http://purl.obolibrary.org/obo/MONDO_0000831
T11 448-456 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T12 539-571 Disease denotes acquired von Willebrand syndrome http://purl.obolibrary.org/obo/MONDO_0020460
T13 573-577 Disease denotes AVWS http://purl.obolibrary.org/obo/MONDO_0020460
T14 637-641 Disease denotes AVWS http://purl.obolibrary.org/obo/MONDO_0020460
T15 645-653 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T16 675-683 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T17 722-726 Disease denotes AVWS http://purl.obolibrary.org/obo/MONDO_0020460
T18 742-786 Disease denotes disseminated intravascular coagulation (DIC) http://purl.obolibrary.org/obo/MONDO_0001243
T19 1048-1056 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T20 1364-1368 Disease denotes AVWS http://purl.obolibrary.org/obo/MONDO_0020460
T21 1384-1392 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T22 1591-1595 Disease denotes AVWS http://purl.obolibrary.org/obo/MONDO_0020460

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1 14-15 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T2 306-314 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T3 598-601 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T4 673-674 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T5 948-954 http://purl.obolibrary.org/obo/UBERON_0001969 denotes Plasma
T6 982-991 http://www.ebi.ac.uk/efo/EFO_0000876 denotes extremely
T7 1014-1030 http://purl.obolibrary.org/obo/CL_0000115 denotes endothelial cell
T8 1077-1083 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T9 1103-1111 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T10 1248-1249 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T11 1409-1410 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T1 423-430 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T2 521-528 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T3 782-785 Chemical denotes DIC http://purl.obolibrary.org/obo/CHEBI_4305|http://purl.obolibrary.org/obo/CHEBI_53092
T5 969-976 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T6 1263-1270 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T7 1448-1461 Chemical denotes anticoagulant http://purl.obolibrary.org/obo/CHEBI_50249
T8 1630-1637 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T9 1642-1645 Chemical denotes DIC http://purl.obolibrary.org/obo/CHEBI_4305|http://purl.obolibrary.org/obo/CHEBI_53092

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T1 769-780 http://purl.obolibrary.org/obo/GO_0050817 denotes coagulation

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
3 16-24 Disease denotes COVID-19 MESH:C000657245
4 25-32 Species denotes Patient Tax:9606
5 75-98 Disease denotes von Willebrand Syndrome MESH:D014842
50 100-108 Species denotes Patients Tax:9606
51 121-129 Disease denotes COVID-19 MESH:C000657245
52 171-183 Disease denotes coagulopathy MESH:D001778
53 194-204 Disease denotes thrombosis MESH:D013927
54 206-224 Disease denotes COVID-19 pneumonia MESH:C000657245
55 244-279 Disease denotes acute respiratory distress syndrome MESH:D012128
56 348-358 Disease denotes thrombosis MESH:D013927
57 363-371 Disease denotes bleeding MESH:D006470
58 392-397 Disease denotes death MESH:D003643
59 423-430 Chemical denotes heparin MESH:D006493
60 448-456 Disease denotes COVID-19 MESH:C000657245
61 457-465 Species denotes patients Tax:9606
62 484-492 Disease denotes bleeding MESH:D006470
63 521-528 Chemical denotes heparin MESH:D006493
64 548-571 Disease denotes von Willebrand syndrome MESH:D014842
65 573-577 Disease denotes AVWS
66 624-632 Disease denotes bleeding MESH:D006470
67 637-641 Disease denotes AVWS
68 645-653 Disease denotes COVID-19 MESH:C000657245
69 654-662 Species denotes patients Tax:9606
70 675-683 Disease denotes COVID-19 MESH:C000657245
71 684-691 Species denotes patient Tax:9606
72 708-716 Disease denotes bleeding MESH:D006470
73 722-726 Disease denotes AVWS
74 742-780 Disease denotes disseminated intravascular coagulation MESH:D004211
75 782-785 Disease denotes DIC MESH:D004211
76 835-838 Gene denotes VWF Gene:7450
77 965-968 Gene denotes VWF Gene:7450
78 1048-1056 Disease denotes COVID-19 MESH:C000657245
79 1094-1102 Gene denotes ADAMTS13 Gene:11093
80 1162-1169 Species denotes patient Tax:9606
81 1219-1227 Disease denotes bleeding MESH:D006470
82 1263-1270 Chemical denotes heparin MESH:D006493
83 1297-1312 Disease denotes thromboembolism MESH:D013923
84 1337-1344 Species denotes patient Tax:9606
85 1364-1368 Disease denotes AVWS
86 1373-1376 Disease denotes DIC MESH:D004211
87 1384-1392 Disease denotes COVID-19 MESH:C000657245
88 1393-1401 Species denotes patients Tax:9606
89 1411-1421 Disease denotes thrombotic MESH:D013927
90 1512-1529 Disease denotes bleeding symptoms MESH:D051271
91 1591-1595 Disease denotes AVWS
92 1630-1637 Chemical denotes heparin MESH:D006493
93 1642-1645 Disease denotes DIC MESH:D004211

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T1 171-183 Phenotype denotes coagulopathy http://purl.obolibrary.org/obo/HP_0003256
T2 215-224 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T3 250-270 Phenotype denotes respiratory distress http://purl.obolibrary.org/obo/HP_0002098
T4 742-780 Phenotype denotes disseminated intravascular coagulation http://purl.obolibrary.org/obo/HP_0005521
T5 782-785 Phenotype denotes DIC http://purl.obolibrary.org/obo/HP_0005521
T6 1297-1312 Phenotype denotes thromboembolism http://purl.obolibrary.org/obo/HP_0001907
T7 1642-1645 Phenotype denotes DIC http://purl.obolibrary.org/obo/HP_0005521

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T1 0-45 Sentence denotes Management of a COVID-19 Patient during ECMO:
T2 46-99 Sentence denotes Paying Attention to Acquired von Willebrand Syndrome.
T3 100-205 Sentence denotes Patients with severe COVID-19 often experience complications including coagulopathy and fatal thrombosis.
T4 206-398 Sentence denotes COVID-19 pneumonia sometimes leads to acute respiratory distress syndrome, requiring extracorporeal membrane oxygenation (ECMO), during which thrombosis and bleeding are major causes of death.
T5 399-579 Sentence denotes Anticoagulation such as heparin is essential for COVID-19 patients on ECMO; however, bleeding might be caused by not only heparin, but also acquired von Willebrand syndrome (AVWS).
T6 580-799 Sentence denotes To date, no study has examined ECMO-related bleeding and AVWS in COVID-19 patients.We report a COVID-19 patient who experienced bleeding from AVWS in addition to disseminated intravascular coagulation (DIC) during ECMO.
T7 800-947 Sentence denotes The level of high-molecular weight VWF multimers decreased during ECMO therapy, and these findings promptly improved after discontinuation of ECMO.
T8 948-1057 Sentence denotes Plasma levels of VWF antigen were extremely high, probably due to endothelial cell damage caused by COVID-19.
T9 1058-1157 Sentence denotes On the other hand, plasma levels of ADAMTS13 activity were moderately reduced, to 20-30% of normal.
T10 1158-1313 Sentence denotes The patient was successfully treated with cryoprecipitate in bleeding during ECMO without a reduction in heparin, which might have induced thromboembolism.
T11 1314-1470 Sentence denotes Bleeding found in this patient might be caused by AVWS and DIC.Severe COVID-19 patients are in a thrombotic state and need to receive anticoagulant therapy.
T12 1471-1548 Sentence denotes However, once they receive ECMO therapy, bleeding symptoms could be observed.
T13 1549-1646 Sentence denotes In such cases, physicians should think of AVWS in addition to the side effect of heparin and DIC.