PubMed:33089863
Annnotations
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T1 | 87-92 | Body_part | denotes | Bowel | http://purl.org/sig/ont/fma/fma7199 |
T2 | 430-435 | Body_part | denotes | bowel | http://purl.org/sig/ont/fma/fma7199 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T1 | 38-46 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T2 | 47-56 | Disease | denotes | Infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T3 | 74-101 | Disease | denotes | Inflammatory Bowel Diseases | http://purl.obolibrary.org/obo/MONDO_0005265 |
T4 | 207-231 | Disease | denotes | coronavirus disease 2019 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T5 | 233-241 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T6 | 359-367 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T7 | 417-443 | Disease | denotes | inflammatory bowel disease | http://purl.obolibrary.org/obo/MONDO_0005265 |
T8 | 445-448 | Disease | denotes | IBD | http://purl.obolibrary.org/obo/MONDO_0005052|http://purl.obolibrary.org/obo/MONDO_0005265 |
T10 | 524-527 | Disease | denotes | IBD | http://purl.obolibrary.org/obo/MONDO_0005052|http://purl.obolibrary.org/obo/MONDO_0005265 |
T12 | 627-635 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T13 | 693-740 | Disease | denotes | severe acute respiratory syndrome coronavirus 2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T14 | 693-726 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
T15 | 838-846 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T16 | 894-897 | Disease | denotes | IBD | http://purl.obolibrary.org/obo/MONDO_0005052|http://purl.obolibrary.org/obo/MONDO_0005265 |
T18 | 928-936 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T19 | 991-994 | Disease | denotes | IBD | http://purl.obolibrary.org/obo/MONDO_0005052|http://purl.obolibrary.org/obo/MONDO_0005265 |
T21 | 1021-1029 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T22 | 1043-1051 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T23 | 1304-1312 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T24 | 1385-1392 | Disease | denotes | obesity | http://purl.obolibrary.org/obo/MONDO_0011122 |
T25 | 1430-1438 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T26 | 1583-1590 | Disease | denotes | obesity | http://purl.obolibrary.org/obo/MONDO_0011122 |
T27 | 1655-1663 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T28 | 1664-1673 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T29 | 1771-1779 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T30 | 1829-1832 | Disease | denotes | IBD | http://purl.obolibrary.org/obo/MONDO_0005052|http://purl.obolibrary.org/obo/MONDO_0005265 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 243-246 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T2 | 371-372 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T3 | 483-485 | http://purl.obolibrary.org/obo/CLO_0050510 | denotes | 18 |
T4 | 647-648 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T5 | 684-688 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | test |
T6 | 877-878 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T7 | 1413-1414 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T8 | 1783-1784 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T1 | 324-339 | Chemical | denotes | immunomodulator | http://purl.obolibrary.org/obo/CHEBI_50846 |
LitCovid-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T1 | 74-101 | Phenotype | denotes | Inflammatory Bowel Diseases | http://purl.obolibrary.org/obo/HP_0002037 |
T2 | 417-443 | Phenotype | denotes | inflammatory bowel disease | http://purl.obolibrary.org/obo/HP_0002037 |
T3 | 445-448 | Phenotype | denotes | IBD | http://purl.obolibrary.org/obo/HP_0002037 |
T4 | 524-527 | Phenotype | denotes | IBD | http://purl.obolibrary.org/obo/HP_0002037 |
T5 | 894-897 | Phenotype | denotes | IBD | http://purl.obolibrary.org/obo/HP_0002037 |
T6 | 991-994 | Phenotype | denotes | IBD | http://purl.obolibrary.org/obo/HP_0002037 |
T7 | 1385-1392 | Phenotype | denotes | obesity | http://purl.obolibrary.org/obo/HP_0001513 |
T8 | 1583-1590 | Phenotype | denotes | obesity | http://purl.obolibrary.org/obo/HP_0001513 |
T9 | 1829-1832 | Phenotype | denotes | IBD | http://purl.obolibrary.org/obo/HP_0002037 |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
4 | 38-46 | Disease | denotes | COVID-19 | MESH:C000657245 |
5 | 47-56 | Disease | denotes | Infection | MESH:D007239 |
6 | 60-68 | Species | denotes | Patients | Tax:9606 |
7 | 74-101 | Disease | denotes | Inflammatory Bowel Diseases | MESH:D015212 |
37 | 201-226 | Disease | denotes | novel coronavirus disease | MESH:C000657245 |
38 | 233-241 | Disease | denotes | COVID-19 | MESH:C000657245 |
39 | 359-367 | Disease | denotes | COVID-19 | MESH:C000657245 |
40 | 403-411 | Species | denotes | patients | Tax:9606 |
41 | 417-443 | Disease | denotes | inflammatory bowel disease | MESH:D015212 |
42 | 445-448 | Disease | denotes | IBD | MESH:D015212 |
43 | 474-482 | Species | denotes | patients | Tax:9606 |
44 | 524-527 | Disease | denotes | IBD | MESH:D015212 |
45 | 627-635 | Disease | denotes | COVID-19 | MESH:C000657245 |
46 | 693-740 | Species | denotes | severe acute respiratory syndrome coronavirus 2 | Tax:2697049 |
47 | 838-846 | Disease | denotes | COVID-19 | MESH:C000657245 |
48 | 894-897 | Disease | denotes | IBD | MESH:D015212 |
49 | 898-906 | Species | denotes | patients | Tax:9606 |
50 | 928-936 | Disease | denotes | COVID-19 | MESH:C000657245 |
51 | 991-994 | Disease | denotes | IBD | MESH:D015212 |
52 | 995-1003 | Species | denotes | patients | Tax:9606 |
53 | 1021-1029 | Disease | denotes | COVID-19 | MESH:C000657245 |
54 | 1043-1051 | Disease | denotes | COVID-19 | MESH:C000657245 |
55 | 1072-1080 | Species | denotes | patients | Tax:9606 |
56 | 1304-1312 | Disease | denotes | COVID-19 | MESH:C000657245 |
57 | 1385-1392 | Disease | denotes | obesity | MESH:D009765 |
58 | 1430-1438 | Disease | denotes | COVID-19 | MESH:C000657245 |
59 | 1562-1567 | Disease | denotes | death | MESH:D003643 |
60 | 1583-1590 | Disease | denotes | obesity | MESH:D009765 |
61 | 1655-1663 | Disease | denotes | COVID-19 | MESH:C000657245 |
62 | 1664-1673 | Disease | denotes | infection | MESH:D007239 |
63 | 1771-1779 | Disease | denotes | COVID-19 | MESH:C000657245 |
64 | 1815-1823 | Species | denotes | patients | Tax:9606 |
65 | 1829-1832 | Disease | denotes | IBD | MESH:D015212 |
Inflammaging
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-102 | Sentence | denotes | Immunosuppressive Therapy and Risk of COVID-19 Infection in Patients With Inflammatory Bowel Diseases. |
T2 | 103-114 | Sentence | denotes | BACKGROUND: |
T3 | 115-268 | Sentence | denotes | The effect of immunosuppressive treatment for immune-mediated diseases on risk of the novel coronavirus disease 2019 (COVID-19) has not been established. |
T4 | 269-450 | Sentence | denotes | We aimed to define the effect of targeted biologic and immunomodulator therapy on risk of COVID-19 in a multi-institutional cohort of patients with inflammatory bowel disease (IBD). |
T5 | 451-459 | Sentence | denotes | METHODS: |
T6 | 460-587 | Sentence | denotes | We identified patients 18 years and older who received care for IBD at Partners Healthcare between January 2019 and April 2020. |
T7 | 588-741 | Sentence | denotes | The primary outcome was development of COVID-19 defined as a positive polymerase chain reaction test for severe acute respiratory syndrome coronavirus 2. |
T8 | 742-864 | Sentence | denotes | Multivariable regression models were used to examine the effect of immunosuppression on risk of COVID-19 and its outcomes. |
T9 | 865-873 | Sentence | denotes | RESULTS: |
T10 | 874-937 | Sentence | denotes | In a cohort of 5302 IBD patients, 39 (0.7%) developed COVID-19. |
T11 | 938-1030 | Sentence | denotes | There was no difference in age, sex, or race between IBD patients with and without COVID-19. |
T12 | 1031-1170 | Sentence | denotes | The rate of COVID-19 was similar between patients treated with immunosuppression (0.8%) compared with those who were not (0.64%; P = 0.55). |
T13 | 1171-1368 | Sentence | denotes | After adjusting for age, sex, race, and comorbidities, use of immunosuppressive therapy was not associated with an increased risk of COVID-19 (odds ratio, 1.73; 95% confidence interval, 0.82-3.63). |
T14 | 1369-1495 | Sentence | denotes | The presence of obesity was associated with a higher risk of COVID-19 (odds ratio, 8.29; 95% confidence interval, 3.72-18.47). |
T15 | 1496-1568 | Sentence | denotes | There were 7 hospitalizations, 3 intensive care unit stays, and 1 death. |
T16 | 1569-1674 | Sentence | denotes | Older age and obesity but not immunosuppressive treatment were associated with severe COVID-19 infection. |
T17 | 1675-1687 | Sentence | denotes | CONCLUSIONS: |
T18 | 1688-1833 | Sentence | denotes | The use of systemic immunosuppression was not associated with an increased risk of COVID-19 in a multi-institutional cohort of patients with IBD. |
T1 | 0-102 | Sentence | denotes | Immunosuppressive Therapy and Risk of COVID-19 Infection in Patients With Inflammatory Bowel Diseases. |
T2 | 103-114 | Sentence | denotes | BACKGROUND: |
T3 | 115-268 | Sentence | denotes | The effect of immunosuppressive treatment for immune-mediated diseases on risk of the novel coronavirus disease 2019 (COVID-19) has not been established. |
T4 | 269-450 | Sentence | denotes | We aimed to define the effect of targeted biologic and immunomodulator therapy on risk of COVID-19 in a multi-institutional cohort of patients with inflammatory bowel disease (IBD). |
T5 | 451-459 | Sentence | denotes | METHODS: |
T6 | 460-587 | Sentence | denotes | We identified patients 18 years and older who received care for IBD at Partners Healthcare between January 2019 and April 2020. |
T7 | 588-741 | Sentence | denotes | The primary outcome was development of COVID-19 defined as a positive polymerase chain reaction test for severe acute respiratory syndrome coronavirus 2. |
T8 | 742-864 | Sentence | denotes | Multivariable regression models were used to examine the effect of immunosuppression on risk of COVID-19 and its outcomes. |
T9 | 865-873 | Sentence | denotes | RESULTS: |
T10 | 874-937 | Sentence | denotes | In a cohort of 5302 IBD patients, 39 (0.7%) developed COVID-19. |
T11 | 938-1030 | Sentence | denotes | There was no difference in age, sex, or race between IBD patients with and without COVID-19. |
T12 | 1031-1170 | Sentence | denotes | The rate of COVID-19 was similar between patients treated with immunosuppression (0.8%) compared with those who were not (0.64%; P = 0.55). |
T13 | 1171-1368 | Sentence | denotes | After adjusting for age, sex, race, and comorbidities, use of immunosuppressive therapy was not associated with an increased risk of COVID-19 (odds ratio, 1.73; 95% confidence interval, 0.82-3.63). |
T14 | 1369-1495 | Sentence | denotes | The presence of obesity was associated with a higher risk of COVID-19 (odds ratio, 8.29; 95% confidence interval, 3.72-18.47). |
T15 | 1496-1568 | Sentence | denotes | There were 7 hospitalizations, 3 intensive care unit stays, and 1 death. |
T16 | 1569-1674 | Sentence | denotes | Older age and obesity but not immunosuppressive treatment were associated with severe COVID-19 infection. |
T17 | 1675-1687 | Sentence | denotes | CONCLUSIONS: |
T18 | 1688-1833 | Sentence | denotes | The use of systemic immunosuppression was not associated with an increased risk of COVID-19 in a multi-institutional cohort of patients with IBD. |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-102 | Sentence | denotes | Immunosuppressive Therapy and Risk of COVID-19 Infection in Patients With Inflammatory Bowel Diseases. |
T2 | 103-114 | Sentence | denotes | BACKGROUND: |
T3 | 115-268 | Sentence | denotes | The effect of immunosuppressive treatment for immune-mediated diseases on risk of the novel coronavirus disease 2019 (COVID-19) has not been established. |
T4 | 269-450 | Sentence | denotes | We aimed to define the effect of targeted biologic and immunomodulator therapy on risk of COVID-19 in a multi-institutional cohort of patients with inflammatory bowel disease (IBD). |
T5 | 451-459 | Sentence | denotes | METHODS: |
T6 | 460-587 | Sentence | denotes | We identified patients 18 years and older who received care for IBD at Partners Healthcare between January 2019 and April 2020. |
T7 | 588-741 | Sentence | denotes | The primary outcome was development of COVID-19 defined as a positive polymerase chain reaction test for severe acute respiratory syndrome coronavirus 2. |
T8 | 742-864 | Sentence | denotes | Multivariable regression models were used to examine the effect of immunosuppression on risk of COVID-19 and its outcomes. |
T9 | 865-873 | Sentence | denotes | RESULTS: |
T10 | 874-937 | Sentence | denotes | In a cohort of 5302 IBD patients, 39 (0.7%) developed COVID-19. |
T11 | 938-1030 | Sentence | denotes | There was no difference in age, sex, or race between IBD patients with and without COVID-19. |
T12 | 1031-1170 | Sentence | denotes | The rate of COVID-19 was similar between patients treated with immunosuppression (0.8%) compared with those who were not (0.64%; P = 0.55). |
T13 | 1171-1368 | Sentence | denotes | After adjusting for age, sex, race, and comorbidities, use of immunosuppressive therapy was not associated with an increased risk of COVID-19 (odds ratio, 1.73; 95% confidence interval, 0.82-3.63). |
T14 | 1369-1495 | Sentence | denotes | The presence of obesity was associated with a higher risk of COVID-19 (odds ratio, 8.29; 95% confidence interval, 3.72-18.47). |
T15 | 1496-1568 | Sentence | denotes | There were 7 hospitalizations, 3 intensive care unit stays, and 1 death. |
T16 | 1569-1674 | Sentence | denotes | Older age and obesity but not immunosuppressive treatment were associated with severe COVID-19 infection. |
T17 | 1675-1687 | Sentence | denotes | CONCLUSIONS: |
T18 | 1688-1833 | Sentence | denotes | The use of systemic immunosuppression was not associated with an increased risk of COVID-19 in a multi-institutional cohort of patients with IBD. |