PubMed:33089039
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T1 | 43-53 | Body_part | denotes | sinus node | http://purl.org/sig/ont/fma/fma9477 |
| T2 | 245-255 | Body_part | denotes | sinus node | http://purl.org/sig/ont/fma/fma9477 |
| T3 | 780-785 | Body_part | denotes | heart | http://purl.org/sig/ont/fma/fma7088 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 780-785 | Body_part | denotes | heart | http://purl.obolibrary.org/obo/UBERON_0000948 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 22-30 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T2 | 124-132 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T3 | 290-298 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T4 | 402-410 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T5 | 536-544 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T6 | 651-670 | Disease | denotes | respiratory failure | http://purl.obolibrary.org/obo/MONDO_0021113 |
| T7 | 684-692 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T8 | 693-702 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
| T9 | 815-826 | Disease | denotes | hypotension | http://purl.obolibrary.org/obo/MONDO_0005468 |
| T10 | 905-920 | Disease | denotes | aortic aneurysm | http://purl.obolibrary.org/obo/MONDO_0005160 |
| T11 | 922-934 | Disease | denotes | hypertension | http://purl.obolibrary.org/obo/MONDO_0005044 |
| T12 | 993-1001 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T13 | 1024-1043 | Disease | denotes | respiratory failure | http://purl.obolibrary.org/obo/MONDO_0021113 |
| T14 | 1277-1285 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T15 | 1386-1394 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T16 | 1403-1426 | Disease | denotes | myocardial inflammation | http://purl.obolibrary.org/obo/MONDO_0004496 |
| T17 | 1414-1426 | Disease | denotes | inflammation | http://purl.obolibrary.org/obo/MONDO_0021166 |
| T18 | 1481-1489 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 67-68 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T2 | 559-560 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T3 | 573-579 | http://purl.obolibrary.org/obo/UBERON_0003100 | denotes | female |
| T4 | 753-754 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T5 | 780-785 | http://purl.obolibrary.org/obo/UBERON_0000948 | denotes | heart |
| T6 | 780-785 | http://purl.obolibrary.org/obo/UBERON_0007100 | denotes | heart |
| T7 | 780-785 | http://purl.obolibrary.org/obo/UBERON_0015228 | denotes | heart |
| T8 | 780-785 | http://www.ebi.ac.uk/efo/EFO_0000815 | denotes | heart |
| T9 | 856-860 | http://purl.obolibrary.org/obo/UBERON_0003101 | denotes | male |
| T10 | 856-860 | http://www.ebi.ac.uk/efo/EFO_0000970 | denotes | male |
| T11 | 866-867 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T12 | 905-911 | http://www.ebi.ac.uk/efo/EFO_0000265 | denotes | aortic |
| T13 | 1301-1304 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T1 | 856-860 | Chemical | denotes | male | http://purl.obolibrary.org/obo/CHEBI_30780 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 952-957 | http://purl.obolibrary.org/obo/GO_0030431 | denotes | sleep |
| T2 | 1176-1182 | http://purl.obolibrary.org/obo/GO_0048511 | denotes | rhythm |
| T3 | 1414-1426 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammation |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 2 | 22-30 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 3 | 43-65 | Disease | denotes | sinus node dysfunction | MESH:D012804 |
| 34 | 100-114 | Disease | denotes | coronavirus-19 | MESH:C000657245 |
| 35 | 124-132 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 36 | 194-203 | Disease | denotes | mortality | MESH:D003643 |
| 37 | 245-267 | Disease | denotes | sinus node dysfunction | MESH:D012804 |
| 38 | 290-298 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 39 | 402-410 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 40 | 411-419 | Species | denotes | patients | Tax:9606 |
| 41 | 503-511 | Species | denotes | patients | Tax:9606 |
| 42 | 536-544 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 43 | 546-553 | Species | denotes | Patient | Tax:9606 |
| 44 | 643-670 | Disease | denotes | hypoxic respiratory failure | MESH:D012131 |
| 45 | 684-702 | Disease | denotes | COVID-19 pneumonia | MESH:C000657245 |
| 46 | 727-744 | Disease | denotes | sinus bradycardia | MESH:D012804 |
| 47 | 815-826 | Disease | denotes | hypotension | MESH:D007022 |
| 48 | 828-835 | Species | denotes | Patient | Tax:9606 |
| 49 | 905-920 | Disease | denotes | aortic aneurysm | MESH:D001014 |
| 50 | 922-934 | Disease | denotes | hypertension | MESH:D006973 |
| 51 | 940-964 | Disease | denotes | obstructive sleep apnoea | MESH:D012893 |
| 52 | 993-1001 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 53 | 1010-1043 | Disease | denotes | acute hypoxic respiratory failure | MESH:D012120 |
| 54 | 1068-1085 | Disease | denotes | sinus bradycardia | MESH:D012804 |
| 55 | 1227-1235 | Species | denotes | patients | Tax:9606 |
| 56 | 1252-1263 | Disease | denotes | bradycardia | MESH:D001919 |
| 57 | 1277-1285 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 58 | 1372-1380 | Species | denotes | patients | Tax:9606 |
| 59 | 1386-1394 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 60 | 1414-1426 | Disease | denotes | inflammation | MESH:D007249 |
| 61 | 1457-1465 | Species | denotes | Patients | Tax:9606 |
| 62 | 1481-1489 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 63 | 1541-1556 | Disease | denotes | bradyarrhythmia | MESH:D001919 |
Inflammaging
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-81 | Sentence | denotes | Novel coronavirus 19 (COVID-19) associated sinus node dysfunction: a case series. |
| T2 | 82-93 | Sentence | denotes | Background: |
| T3 | 94-204 | Sentence | denotes | Novel coronavirus-19 disease (COVID-19) is associated with significant cardiovascular morbidity and mortality. |
| T4 | 205-299 | Sentence | denotes | To date, there have not been reports of sinus node dysfunction (SND) associated with COVID-19. |
| T5 | 300-447 | Sentence | denotes | This case series describes clinical characteristics, potential mechanisms, and short-term outcomes of COVID-19 patients who experience de novo SND. |
| T6 | 448-461 | Sentence | denotes | Case summary: |
| T7 | 462-545 | Sentence | denotes | We present two cases of new-onset SND in patients recently diagnosed with COVID-19. |
| T8 | 546-827 | Sentence | denotes | Patient 1 is a 70-year-old female with no major past medical history who was intubated for acute hypoxic respiratory failure secondary to COVID-19 pneumonia and developed new-onset sinus bradycardia without a compensatory increase in heart rate in response to relative hypotension. |
| T9 | 828-1183 | Sentence | denotes | Patient 2 is an 81-year-old male with a past medical history of an ascending aortic aneurysm, hypertension, and obstructive sleep apnoea who required intubation for COVID-19-induced acute hypoxic respiratory failure and exhibited new-onset sinus bradycardia followed by numerous episodes of haemodynamically significant accelerated idioventricular rhythm. |
| T10 | 1184-1264 | Sentence | denotes | Two weeks following the onset of SND, both patients remain in sinus bradycardia. |
| T11 | 1265-1335 | Sentence | denotes | Discussion: COVID-19-associated SND has not previously been described. |
| T12 | 1336-1456 | Sentence | denotes | The potential mechanisms for SND in patients with COVID-19 include myocardial inflammation or direct viral infiltration. |
| T13 | 1457-1586 | Sentence | denotes | Patients diagnosed with COVID-19 should be monitored closely for the development of bradyarrhythmia and haemodynamic instability. |
| T1 | 0-81 | Sentence | denotes | Novel coronavirus 19 (COVID-19) associated sinus node dysfunction: a case series. |
| T2 | 82-93 | Sentence | denotes | Background: |
| T3 | 94-204 | Sentence | denotes | Novel coronavirus-19 disease (COVID-19) is associated with significant cardiovascular morbidity and mortality. |
| T4 | 205-299 | Sentence | denotes | To date, there have not been reports of sinus node dysfunction (SND) associated with COVID-19. |
| T5 | 300-447 | Sentence | denotes | This case series describes clinical characteristics, potential mechanisms, and short-term outcomes of COVID-19 patients who experience de novo SND. |
| T6 | 448-461 | Sentence | denotes | Case summary: |
| T7 | 462-545 | Sentence | denotes | We present two cases of new-onset SND in patients recently diagnosed with COVID-19. |
| T8 | 546-827 | Sentence | denotes | Patient 1 is a 70-year-old female with no major past medical history who was intubated for acute hypoxic respiratory failure secondary to COVID-19 pneumonia and developed new-onset sinus bradycardia without a compensatory increase in heart rate in response to relative hypotension. |
| T9 | 828-1183 | Sentence | denotes | Patient 2 is an 81-year-old male with a past medical history of an ascending aortic aneurysm, hypertension, and obstructive sleep apnoea who required intubation for COVID-19-induced acute hypoxic respiratory failure and exhibited new-onset sinus bradycardia followed by numerous episodes of haemodynamically significant accelerated idioventricular rhythm. |
| T10 | 1184-1264 | Sentence | denotes | Two weeks following the onset of SND, both patients remain in sinus bradycardia. |
| T11 | 1265-1335 | Sentence | denotes | Discussion: COVID-19-associated SND has not previously been described. |
| T12 | 1336-1456 | Sentence | denotes | The potential mechanisms for SND in patients with COVID-19 include myocardial inflammation or direct viral infiltration. |
| T13 | 1457-1586 | Sentence | denotes | Patients diagnosed with COVID-19 should be monitored closely for the development of bradyarrhythmia and haemodynamic instability. |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-81 | Sentence | denotes | Novel coronavirus 19 (COVID-19) associated sinus node dysfunction: a case series. |
| T2 | 82-93 | Sentence | denotes | Background: |
| T3 | 94-204 | Sentence | denotes | Novel coronavirus-19 disease (COVID-19) is associated with significant cardiovascular morbidity and mortality. |
| T4 | 205-299 | Sentence | denotes | To date, there have not been reports of sinus node dysfunction (SND) associated with COVID-19. |
| T5 | 300-447 | Sentence | denotes | This case series describes clinical characteristics, potential mechanisms, and short-term outcomes of COVID-19 patients who experience de novo SND. |
| T6 | 448-461 | Sentence | denotes | Case summary: |
| T7 | 462-545 | Sentence | denotes | We present two cases of new-onset SND in patients recently diagnosed with COVID-19. |
| T8 | 546-827 | Sentence | denotes | Patient 1 is a 70-year-old female with no major past medical history who was intubated for acute hypoxic respiratory failure secondary to COVID-19 pneumonia and developed new-onset sinus bradycardia without a compensatory increase in heart rate in response to relative hypotension. |
| T9 | 828-1183 | Sentence | denotes | Patient 2 is an 81-year-old male with a past medical history of an ascending aortic aneurysm, hypertension, and obstructive sleep apnoea who required intubation for COVID-19-induced acute hypoxic respiratory failure and exhibited new-onset sinus bradycardia followed by numerous episodes of haemodynamically significant accelerated idioventricular rhythm. |
| T10 | 1184-1264 | Sentence | denotes | Two weeks following the onset of SND, both patients remain in sinus bradycardia. |
| T11 | 1265-1335 | Sentence | denotes | Discussion: COVID-19-associated SND has not previously been described. |
| T12 | 1336-1456 | Sentence | denotes | The potential mechanisms for SND in patients with COVID-19 include myocardial inflammation or direct viral infiltration. |
| T13 | 1457-1586 | Sentence | denotes | Patients diagnosed with COVID-19 should be monitored closely for the development of bradyarrhythmia and haemodynamic instability. |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 651-670 | Phenotype | denotes | respiratory failure | http://purl.obolibrary.org/obo/HP_0002878 |
| T2 | 693-702 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
| T3 | 727-744 | Phenotype | denotes | sinus bradycardia | http://purl.obolibrary.org/obo/HP_0001688 |
| T4 | 768-790 | Phenotype | denotes | increase in heart rate | http://purl.obolibrary.org/obo/HP_0001649 |
| T5 | 815-826 | Phenotype | denotes | hypotension | http://purl.obolibrary.org/obo/HP_0002615 |
| T6 | 895-920 | Phenotype | denotes | ascending aortic aneurysm | http://purl.obolibrary.org/obo/HP_0004970 |
| T7 | 922-934 | Phenotype | denotes | hypertension | http://purl.obolibrary.org/obo/HP_0000822 |
| T8 | 940-964 | Phenotype | denotes | obstructive sleep apnoea | http://purl.obolibrary.org/obo/HP_0002870 |
| T9 | 1024-1043 | Phenotype | denotes | respiratory failure | http://purl.obolibrary.org/obo/HP_0002878 |
| T10 | 1068-1085 | Phenotype | denotes | sinus bradycardia | http://purl.obolibrary.org/obo/HP_0001688 |
| T11 | 1246-1263 | Phenotype | denotes | sinus bradycardia | http://purl.obolibrary.org/obo/HP_0001688 |