PubMed:33060199 / 312-603 JSONTXT

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T1","span":{"begin":0,"end":1},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T2","span":{"begin":27,"end":32},"obj":"http://purl.obolibrary.org/obo/UBERON_0007688"},{"id":"T3","span":{"begin":33,"end":36},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T4","span":{"begin":121,"end":127},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T5","span":{"begin":133,"end":139},"obj":"http://purl.obolibrary.org/obo/UBERON_0002553"},{"id":"T6","span":{"begin":285,"end":290},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"}],"text":"A critical question in the field has been what the protonation states of the ionizable residues in the substrate-binding active site cavity are; resolving this point would help understand the catalytic details of the enzyme and inform rational drug development against this pernicious virus."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T2","span":{"begin":244,"end":248},"obj":"Chemical"}],"attributes":[{"id":"A2","pred":"chebi_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/CHEBI_23888"}],"text":"A critical question in the field has been what the protonation states of the ionizable residues in the substrate-binding active site cavity are; resolving this point would help understand the catalytic details of the enzyme and inform rational drug development against this pernicious virus."}

{"project":"LitCovid-sentences","denotations":[{"id":"T4","span":{"begin":0,"end":291},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"A critical question in the field has been what the protonation states of the ionizable residues in the substrate-binding active site cavity are; resolving this point would help understand the catalytic details of the enzyme and inform rational drug development against this pernicious virus."}

{"project":"sentences","denotations":[{"id":"T4","span":{"begin":0,"end":291},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"A critical question in the field has been what the protonation states of the ionizable residues in the substrate-binding active site cavity are; resolving this point would help understand the catalytic details of the enzyme and inform rational drug development against this pernicious virus."}

{"project":"Anatomy-UBERON","denotations":[{"id":"T1","span":{"begin":133,"end":139},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"uberon_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/UBERON_0002553"}],"text":"A critical question in the field has been what the protonation states of the ionizable residues in the substrate-binding active site cavity are; resolving this point would help understand the catalytic details of the enzyme and inform rational drug development against this pernicious virus."}