PubMed:33055313
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T1 | 1891-1897 | Body_part | denotes | embryo | http://purl.org/sig/ont/fma/fma296970 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 1891-1897 | Body_part | denotes | embryo | http://purl.obolibrary.org/obo/UBERON_0000922 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 29-37 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T2 | 129-137 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T3 | 172-219 | Disease | denotes | severe acute respiratory syndrome coronavirus 2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T4 | 172-205 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T5 | 221-229 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T6 | 356-364 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T7 | 582-590 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T8 | 630-638 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T9 | 702-710 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T10 | 1406-1414 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T11 | 1720-1728 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 157-167 | http://purl.obolibrary.org/obo/BFO_0000030 | denotes | Objectives |
| T2 | 383-386 | http://purl.obolibrary.org/obo/PR_000001343 | denotes | aim |
| T3 | 421-429 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T4 | 969-971 | http://purl.obolibrary.org/obo/CLO_0001382 | denotes | 48 |
| T5 | 985-987 | http://purl.obolibrary.org/obo/CLO_0001000 | denotes | 35 |
| T6 | 1842-1847 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T7 | 1891-1897 | http://purl.obolibrary.org/obo/UBERON_0000922 | denotes | embryo |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T1 | 540-544 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T2 | 1099-1104 | Chemical | denotes | drugs | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T3 | 1158-1163 | Chemical | denotes | drugs | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T4 | 1301-1313 | Chemical | denotes | azithromycin | http://purl.obolibrary.org/obo/CHEBI_2955 |
| T5 | 1373-1385 | Chemical | denotes | azithromycin | http://purl.obolibrary.org/obo/CHEBI_2955 |
| T6 | 1570-1593 | Chemical | denotes | lopinavir and ritonavir | http://purl.obolibrary.org/obo/CHEBI_145924 |
| T7 | 1570-1579 | Chemical | denotes | lopinavir | http://purl.obolibrary.org/obo/CHEBI_31781 |
| T8 | 1584-1593 | Chemical | denotes | ritonavir | http://purl.obolibrary.org/obo/CHEBI_45409 |
| T9 | 1653-1662 | Chemical | denotes | darunavir | http://purl.obolibrary.org/obo/CHEBI_367163 |
| T10 | 1667-1677 | Chemical | denotes | cobicistat | http://purl.obolibrary.org/obo/CHEBI_72291 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 887-896 | http://purl.obolibrary.org/obo/GO_0007595 | denotes | lactation |
| T2 | 1259-1268 | http://purl.obolibrary.org/obo/GO_0007595 | denotes | lactation |
| T3 | 1488-1497 | http://purl.obolibrary.org/obo/GO_0007595 | denotes | lactation |
| T4 | 1560-1569 | http://purl.obolibrary.org/obo/GO_0007595 | denotes | lactation |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 3 | 29-37 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 4 | 61-66 | Species | denotes | women | Tax:9606 |
| 5 | 129-137 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 29 | 172-219 | Species | denotes | severe acute respiratory syndrome coronavirus 2 | Tax:2697049 |
| 30 | 221-229 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 31 | 356-364 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 32 | 582-590 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 33 | 614-622 | Species | denotes | patients | Tax:9606 |
| 34 | 630-638 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 35 | 702-710 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 36 | 734-739 | Species | denotes | women | Tax:9606 |
| 37 | 999-1007 | Species | denotes | patients | Tax:9606 |
| 38 | 1038-1043 | Species | denotes | women | Tax:9606 |
| 39 | 1278-1296 | Chemical | denotes | Hydroxychloroquine | MESH:D006886 |
| 40 | 1301-1313 | Chemical | denotes | azithromycin | MESH:D017963 |
| 41 | 1350-1368 | Chemical | denotes | Hydroxychloroquine | MESH:D006886 |
| 42 | 1373-1385 | Chemical | denotes | azithromycin | MESH:D017963 |
| 43 | 1406-1414 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 44 | 1570-1579 | Chemical | denotes | lopinavir | MESH:D061466 |
| 45 | 1584-1593 | Chemical | denotes | ritonavir | MESH:D019438 |
| 46 | 1653-1662 | Chemical | denotes | darunavir | MESH:D000069454 |
| 47 | 1667-1677 | Chemical | denotes | cobicistat | MESH:D000069547 |
| 48 | 1686-1697 | Chemical | denotes | Tocilizumab | MESH:C502936 |
| 49 | 1720-1728 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 50 | 1842-1847 | Species | denotes | human | Tax:9606 |
| 51 | 1904-1912 | Disease | denotes | toxicity | MESH:D064420 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-156 | Sentence | denotes | Medications prescriptions in COVID-19 pregnant and lactating women: the Bergamo Teratology Information Service experience during COVID-19 outbreak in Italy. |
| T2 | 157-378 | Sentence | denotes | Objectives The severe acute respiratory syndrome coronavirus 2 (COVID-19) outbreak in Italy, especially in Lombardy and Bergamo city, represented probably nowadays one of the first major clusters of COVID-19 in the world. |
| T3 | 379-657 | Sentence | denotes | The aim of this report is to describe the activity of Bergamo Teratology Information Service (TIS) in supporting the public and health-care personnel in case of drug prescriptions in suspected/confirmed COVID-19 pregnant and lactating patients during COVID-19 outbreak in Italy. |
| T4 | 658-806 | Sentence | denotes | Methods All Bergamo TIS requests concerning COVID-19 pregnant and lactating women have been retrospectively evaluated from 1 March to 15 April 2020. |
| T5 | 807-910 | Sentence | denotes | Type of medications, drug's safety profile and compatibility with pregnancy and lactation are reported. |
| T6 | 911-1008 | Sentence | denotes | Results Our service received information calls concerning 48 (9 pregnant, 35 lactating) patients. |
| T7 | 1009-1132 | Sentence | denotes | Among pregnant and lactating women, the requests of information were related to 16 and 60 drugs prescriptions respectively. |
| T8 | 1133-1277 | Sentence | denotes | More than half concerned drugs prescriptions during the first and second trimester (13/16) and during the first six months of lactation (37/60). |
| T9 | 1278-1337 | Sentence | denotes | Hydroxychloroquine and azithromycin were the most involved. |
| T10 | 1338-1498 | Sentence | denotes | Conclusions Hydroxychloroquine and azithromycin at dosages used for COVID-19 may be considered compatible and reasonably safe either in pregnancy and lactation. |
| T11 | 1499-1552 | Sentence | denotes | Antivirals may be considered acceptable in pregnancy. |
| T12 | 1553-1685 | Sentence | denotes | During lactation lopinavir and ritonavir probably exhibit some supportive data from literature that darunavir and cobicistat do not. |
| T13 | 1686-1802 | Sentence | denotes | Tocilizumab may be considered for COVID-19 treatment because no increased malformation rate were observed until now. |
| T14 | 1803-1932 | Sentence | denotes | However caution may be advised because human data are limited and the potential risk of embryo-fetal toxicity cannot be excluded. |