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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T1 364-391 Body_part denotes ribonucleoprotein complexes http://purl.org/sig/ont/fma/fma84762
T2 1066-1070 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 30-34 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T2 540-548 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T3 870-878 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T4 1241-1249 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T5 1575-1583 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1 60-61 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T2 203-204 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T3 331-341 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T4 402-403 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T5 612-613 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T6 789-794 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T7 1066-1070 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T8 1105-1106 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T9 1121-1125 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T10 1141-1142 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T11 1270-1275 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T12 1378-1379 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T13 1461-1468 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T14 1597-1604 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T1 239-252 http://purl.obolibrary.org/obo/GO_0003968 denotes transcriptase
T2 239-252 http://purl.obolibrary.org/obo/GO_0003899 denotes transcriptase
T3 322-341 http://purl.obolibrary.org/obo/GO_0032075 denotes nuclease activation

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
1 30-48 Species denotes SARS coronavirus-2 Tax:2697049
11 540-548 Disease denotes COVID-19 MESH:C000657245
12 556-563 Species denotes patient Tax:9606
13 573-580 Species denotes Patient Tax:9606
14 722-729 Species denotes patient Tax:9606
15 870-880 Species denotes SARS-CoV-2 Tax:2697049
16 1241-1251 Species denotes SARS-CoV-2 Tax:2697049
17 1270-1275 Species denotes human Tax:9606
18 1276-1289 Species denotes coronaviruses Tax:11118
19 1575-1585 Species denotes SARS-CoV-2 Tax:2697049

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T1 0-136 Sentence denotes Rapid, sensitive and specific SARS coronavirus-2 detection: a multi-center comparison between standard qRT-PCR and CRISPR based DETECTR.
T2 137-490 Sentence denotes Recent advances in CRISPR-based diagnostics suggest that DETECTR, a combination of isothermal reverse transcriptase loop mediated amplification (RT-LAMP) and subsequent Cas12 bystander nuclease activation by amplicon targeting ribonucleoprotein complexes, could be a faster and cheaper alternative to qRT-PCR without sacrificing sensitivity/specificity.
T3 491-572 Sentence denotes Here we compare DETECTR with qRT-PCR to diagnose COVID-19 on 378 patient samples.
T4 573-795 Sentence denotes Patient sample dilution assays suggest a higher analytical sensitivity of DETECTR compared to qRT-PCR, however, this was not confirmed in this large patient cohort, were we report 95% reproducibility between the two tests.
T5 796-959 Sentence denotes These data showed that both techniques are equally sensitive in detecting SARS-CoV-2 providing additional value of DETECTR to the currently used qRT-PCR platforms.
T6 960-1071 Sentence denotes For DETECTR, different gRNAs can be used simultaneously to obviate negative results due to mutations in N-gene.
T7 1072-1197 Sentence denotes Lateral flow strips, suitable as a point of care test (POCT), showed a 100% correlation to the high-throughput DETECTR assay.
T8 1198-1290 Sentence denotes Importantly, DETECTR was 100% specific for SARS-CoV-2 relative to other human coronaviruses.
T9 1291-1605 Sentence denotes As there is no need for specialized equipment, DETECTR could be rapidly implemented as a complementary technically independent approach to qRT-PCR thereby increasing the testing capacity of medical microbiological laboratories and relieving the existent PCR-platforms for routine non-SARS-CoV-2 diagnostic testing.