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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T1 224-235 Body_part denotes pneumocytes http://purl.org/sig/ont/fma/fma62499
T2 248-256 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T3 719-721 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T4 777-779 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T5 1227-1229 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T6 1233-1235 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T7 1627-1629 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T8 1637-1639 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 87-95 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T2 98-107 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T3 280-288 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T4 291-300 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T5 443-451 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T6 454-463 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T7 541-549 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T8 552-561 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T9 1698-1706 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T10 1709-1718 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1 140-150 http://purl.obolibrary.org/obo/BFO_0000030 denotes OBJECTIVES
T2 563-571 http://purl.obolibrary.org/obo/UBERON_0001637 denotes arterial
T3 563-571 http://www.ebi.ac.uk/efo/EFO_0000814 denotes arterial
T4 1134-1135 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T5 1291-1293 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T6 1311-1312 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T7 1719-1720 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T1 67-82 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T2 175-184 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T3 404-419 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T4 572-578 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T5 624-630 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T6 662-681 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T7 662-671 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T8 672-681 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T9 702-717 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T10 719-721 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T11 722-727 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T12 740-755 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T13 777-779 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T14 780-785 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T15 836-842 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T16 1011-1017 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T17 1227-1229 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T18 1233-1235 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T19 1236-1241 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T20 1365-1371 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T21 1627-1629 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T22 1637-1639 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462
T23 1640-1645 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T24 1753-1768 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T25 1850-1865 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T1 98-107 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T2 248-262 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T3 291-300 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T4 454-463 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T5 552-561 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T6 1709-1718 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T1 0-139 Sentence denotes Baricitinib improves respiratory function in patients treated with corticosteroids for SARS-CoV-2 pneumonia: an observational cohort study.
T2 140-151 Sentence denotes OBJECTIVES:
T3 152-301 Sentence denotes The Janus kinase (JAK) inhibitor baricitinib may block viral entry into pneumocytes and prevent cytokine storm in patients with SARS-CoV-2 pneumonia.
T4 302-464 Sentence denotes We aimed to assess whether baricitinib improved pulmonary function in patients treated with high-dose corticosteroids for moderate to severe SARS-CoV-2 pneumonia.
T5 465-473 Sentence denotes METHODS:
T6 474-795 Sentence denotes This observational study enrolled patients with moderate to severe SARS-CoV-2 pneumonia [arterial oxygen partial pressure (PaO2)/fraction of inspired oxygen (FiO2) <200 mmHg] who received lopinavir/ritonavir and HCQ plus either corticosteroids (CS group, n = 50) or corticosteroids and baricitinib (BCT-CS group, n = 62).
T7 796-930 Sentence denotes The primary end point was the change in oxygen saturation as measured by pulse oximetry (SpO2)/FiO2 from hospitalization to discharge.
T8 931-1049 Sentence denotes Secondary end points included the proportion of patients requiring supplemental oxygen at discharge and 1 month later.
T9 1050-1124 Sentence denotes Statistics were adjusted by the inverse propensity score weighting (IPSW).
T10 1125-1133 Sentence denotes RESULTS:
T11 1134-1290 Sentence denotes A greater improvement in SpO2/FiO2 from hospitalization to discharge was observed in the BCT-CS vs CS group (mean differences adjusted for IPSW, 49; 95% CI:
T12 1291-1310 Sentence denotes 22, 77; P < 0.001).
T13 1311-1472 Sentence denotes A higher proportion of patients required supplemental oxygen both at discharge (62.0% vs 25.8%; reduction of the risk by 82%, OR adjusted for IPSW, 0.18; 95% CI:
T14 1473-1596 Sentence denotes 0.08, 0.43; P < 0.001) and 1 month later (28.0% vs 12.9%, reduction of the risk by 69%, OR adjusted for IPSW, 0.31; 95% CI:
T15 1597-1646 Sentence denotes 0.11, 0.86; P = 0.024) in the CS vs BCT-CS group.
T16 1647-1661 Sentence denotes CONCLUSIONS: .
T17 1662-1872 Sentence denotes In patients with moderate to severe SARS-CoV-2 pneumonia a combination of baricitinib with corticosteroids was associated with greater improvement in pulmonary function when compared with corticosteroids alone.
T18 1873-1892 Sentence denotes TRIAL REGISTRATION:
T19 1893-2047 Sentence denotes European Network of Centres for Pharmacoepidemiology and Pharmacovigilance, ENCEPP (EUPAS34966, http://www.encepp.eu/encepp/viewResource.htm? id = 34967).

hydroxychloroquine

Id Subject Object Predicate Lexical cue hp_id
T1 98-107 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T2 248-262 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T3 291-300 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T4 454-463 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T5 552-561 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T6 1709-1718 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090