PubMed:33012653
Annnotations
LitCovid_Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 981-994 | https://glytoucan.org/Structures/Glycans/G93424OB | denotes | galactomannan |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 0-8 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T2 | 35-48 | Disease | denotes | aspergillosis | http://purl.obolibrary.org/obo/MONDO_0005657 |
| T3 | 93-103 | Disease | denotes | infections | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T4 | 109-156 | Disease | denotes | severe acute respiratory syndrome coronavirus 2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T5 | 109-142 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T6 | 158-166 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T7 | 247-256 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T8 | 277-301 | Disease | denotes | coronavirus disease 2019 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T9 | 303-311 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T10 | 408-416 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T11 | 443-456 | Disease | denotes | aspergillosis | http://purl.obolibrary.org/obo/MONDO_0005657 |
| T12 | 502-515 | Disease | denotes | infections in | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T13 | 530-538 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T14 | 603-611 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T15 | 640-675 | Disease | denotes | Acute respiratory distress syndrome | http://purl.obolibrary.org/obo/MONDO_0006502 |
| T16 | 646-675 | Disease | denotes | respiratory distress syndrome | http://purl.obolibrary.org/obo/MONDO_0009971 |
| T17 | 889-911 | Disease | denotes | invasive aspergillosis | http://purl.obolibrary.org/obo/MONDO_0000240 |
| T18 | 898-911 | Disease | denotes | aspergillosis | http://purl.obolibrary.org/obo/MONDO_0005657 |
| T19 | 1128-1137 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T20 | 1141-1149 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T21 | 1306-1319 | Disease | denotes | aspergillosis | http://purl.obolibrary.org/obo/MONDO_0005657 |
| T22 | 1526-1534 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T23 | 1649-1662 | Disease | denotes | aspergillosis | http://purl.obolibrary.org/obo/MONDO_0005657 |
| T24 | 1682-1690 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T25 | 1753-1761 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 50-51 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T2 | 84-89 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T3 | 803-809 | http://purl.obolibrary.org/obo/CLO_0007926 | denotes | n = 22 |
| T4 | 837-839 | http://purl.obolibrary.org/obo/CLO_0001302 | denotes | 34 |
| T5 | 995-999 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | test |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T1 | 596-599 | Chemical | denotes | IPA | http://purl.obolibrary.org/obo/CHEBI_17824|http://purl.obolibrary.org/obo/CHEBI_30802 |
| T3 | 981-994 | Chemical | denotes | galactomannan | http://purl.obolibrary.org/obo/CHEBI_27680 |
| T4 | 1201-1213 | Chemical | denotes | voriconazole | http://purl.obolibrary.org/obo/CHEBI_10023 |
| T5 | 1288-1304 | Chemical | denotes | antifungal agent | http://purl.obolibrary.org/obo/CHEBI_35718 |
| T6 | 1330-1335 | Chemical | denotes | azole | http://purl.obolibrary.org/obo/CHEBI_68452 |
| T7 | 1390-1402 | Chemical | denotes | voriconazole | http://purl.obolibrary.org/obo/CHEBI_10023 |
| T8 | 1458-1462 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T9 | 1463-1467 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 2 | 0-8 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 3 | 25-48 | Disease | denotes | pulmonary aspergillosis | MESH:D055732 |
| 40 | 84-103 | Disease | denotes | virus co-infections | MESH:D060085 |
| 41 | 109-156 | Species | denotes | severe acute respiratory syndrome coronavirus 2 | Tax:2697049 |
| 42 | 158-168 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 43 | 232-243 | Species | denotes | Aspergillus | Tax:746128 |
| 44 | 247-256 | Disease | denotes | infection | MESH:D007239 |
| 45 | 263-271 | Species | denotes | patients | Tax:9606 |
| 46 | 277-301 | Disease | denotes | coronavirus disease 2019 | MESH:C000657245 |
| 47 | 303-311 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 48 | 408-416 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 49 | 433-456 | Disease | denotes | pulmonary aspergillosis | MESH:D055732 |
| 50 | 472-483 | Species | denotes | Aspergillus | Tax:746128 |
| 51 | 499-512 | Disease | denotes | co-infections | MESH:D060085 |
| 52 | 516-524 | Species | denotes | patients | Tax:9606 |
| 53 | 530-538 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 54 | 603-611 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 55 | 640-675 | Disease | denotes | Acute respiratory distress syndrome | MESH:D012128 |
| 56 | 755-764 | Disease | denotes | mortality | MESH:D003643 |
| 57 | 889-911 | Disease | denotes | invasive aspergillosis | MESH:D055744 |
| 58 | 981-994 | Chemical | denotes | galactomannan | MESH:C012990 |
| 59 | 1067-1088 | Species | denotes | Aspergillus fumigatus | Tax:746128 |
| 60 | 1128-1137 | Disease | denotes | infection | MESH:D007239 |
| 61 | 1141-1149 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 62 | 1150-1158 | Species | denotes | patients | Tax:9606 |
| 63 | 1172-1190 | Species | denotes | Aspergillus flavus | Tax:5059 |
| 64 | 1201-1213 | Chemical | denotes | voriconazole | MESH:D065819 |
| 65 | 1238-1249 | Species | denotes | Aspergillus | Tax:746128 |
| 66 | 1306-1319 | Disease | denotes | aspergillosis | MESH:D001228 |
| 67 | 1330-1335 | Chemical | denotes | azole | MESH:D001393 |
| 68 | 1346-1357 | Species | denotes | Aspergillus | Tax:746128 |
| 69 | 1390-1402 | Chemical | denotes | voriconazole | MESH:D065819 |
| 70 | 1494-1517 | Disease | denotes | cardiovascular toxicity | MESH:D002318 |
| 71 | 1526-1536 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 72 | 1639-1662 | Disease | denotes | pulmonary aspergillosis | MESH:D055732 |
| 73 | 1682-1690 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 74 | 1691-1699 | Species | denotes | patients | Tax:9606 |
| 75 | 1753-1763 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
LitCovid-PD-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glyco_epitope_db_id |
|---|---|---|---|---|---|
| T1 | 981-994 | GlycoEpitope | denotes | galactomannan | http://www.glycoepitope.jp/epitopes/EP0510 |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 646-666 | Phenotype | denotes | respiratory distress | http://purl.obolibrary.org/obo/HP_0002098 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-49 | Sentence | denotes | COVID-19 associated with pulmonary aspergillosis: |
| T2 | 50-70 | Sentence | denotes | A literature review. |
| T3 | 71-325 | Sentence | denotes | Bacterial or virus co-infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been reported in many studies, however, the knowledge on Aspergillus co-infection among patients with coronavirus disease 2019 (COVID-19) was limited. |
| T4 | 326-457 | Sentence | denotes | This literature review aims to explore and describe the updated information about COVID-19 associated with pulmonary aspergillosis. |
| T5 | 458-578 | Sentence | denotes | We found that Aspergillus spp. can cause co-infections in patients with COVID-19, especially in severe/critical illness. |
| T6 | 579-639 | Sentence | denotes | The incidence of IPA in COVID-19 ranged from 19.6% to 33.3%. |
| T7 | 640-855 | Sentence | denotes | Acute respiratory distress syndrome requiring mechanical ventilation was the common complications, and the overall mortality was high, which could be up to 64.7% (n = 22) in the pooled analysis of 34 reported cases. |
| T8 | 856-961 | Sentence | denotes | The conventional risk factors of invasive aspergillosis were not common among these specific populations. |
| T9 | 962-1066 | Sentence | denotes | Fungus culture and galactomannan test, especially from respiratory specimens could help early diagnosis. |
| T10 | 1067-1191 | Sentence | denotes | Aspergillus fumigatus was the most common species causing co-infection in COVID-19 patients, followed by Aspergillus flavus. |
| T11 | 1192-1375 | Sentence | denotes | Although voriconazole is the recommended anti-Aspergillus agent and also the most commonly used antifungal agent, aspergillosis caused by azole-resistant Aspergillus is also possible. |
| T12 | 1376-1544 | Sentence | denotes | Additionally, voriconazole should be used carefully in the concern of complicated drug-drug interaction and enhancing cardiovascular toxicity on anti-SARS-CoV-2 agents. |
| T13 | 1545-1810 | Sentence | denotes | Finally, this review suggests that clinicians should keep alerting the possible occurrence of pulmonary aspergillosis in severe/critical COVID-19 patients, and aggressively microbiologic study in addition to SARS-CoV-2 via respiratory specimens should be indicated. |