PubMed:32970989 / 334-473
Annnotations
LitCovid_Glycan-Motif-Structure
{"project":"LitCovid_Glycan-Motif-Structure","denotations":[{"id":"T3","span":{"begin":14,"end":21},"obj":"https://glytoucan.org/Structures/Glycans/G00021MO"},{"id":"T4","span":{"begin":14,"end":21},"obj":"https://glytoucan.org/Structures/Glycans/G54161DR"},{"id":"T5","span":{"begin":117,"end":124},"obj":"https://glytoucan.org/Structures/Glycans/G00021MO"},{"id":"T6","span":{"begin":117,"end":124},"obj":"https://glytoucan.org/Structures/Glycans/G54161DR"}],"text":"Both ACE2 and heparin can bind independently to spike protein in vitro, and a ternary complex can be generated using heparin as a scaffold."}
LitCovid-PD-FMA-UBERON
{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T7","span":{"begin":14,"end":21},"obj":"Body_part"},{"id":"T8","span":{"begin":54,"end":61},"obj":"Body_part"},{"id":"T9","span":{"begin":117,"end":124},"obj":"Body_part"}],"attributes":[{"id":"A7","pred":"fma_id","subj":"T7","obj":"http://purl.org/sig/ont/fma/fma82839"},{"id":"A8","pred":"fma_id","subj":"T8","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A9","pred":"fma_id","subj":"T9","obj":"http://purl.org/sig/ont/fma/fma82839"}],"text":"Both ACE2 and heparin can bind independently to spike protein in vitro, and a ternary complex can be generated using heparin as a scaffold."}
LitCovid-PD-CLO
{"project":"LitCovid-PD-CLO","denotations":[{"id":"T2","span":{"begin":76,"end":77},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T3","span":{"begin":128,"end":129},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"Both ACE2 and heparin can bind independently to spike protein in vitro, and a ternary complex can be generated using heparin as a scaffold."}
LitCovid-PD-CHEBI
{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T11","span":{"begin":14,"end":21},"obj":"Chemical"},{"id":"T12","span":{"begin":54,"end":61},"obj":"Chemical"},{"id":"T13","span":{"begin":117,"end":124},"obj":"Chemical"}],"attributes":[{"id":"A11","pred":"chebi_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/CHEBI_28304"},{"id":"A12","pred":"chebi_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A13","pred":"chebi_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/CHEBI_28304"}],"text":"Both ACE2 and heparin can bind independently to spike protein in vitro, and a ternary complex can be generated using heparin as a scaffold."}
LitCovid-sentences
{"project":"LitCovid-sentences","denotations":[{"id":"T4","span":{"begin":0,"end":139},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Both ACE2 and heparin can bind independently to spike protein in vitro, and a ternary complex can be generated using heparin as a scaffold."}
LitCovid-PubTator
{"project":"LitCovid-PubTator","denotations":[{"id":"45","span":{"begin":5,"end":9},"obj":"Gene"},{"id":"46","span":{"begin":14,"end":21},"obj":"Chemical"},{"id":"47","span":{"begin":48,"end":53},"obj":"Gene"},{"id":"48","span":{"begin":117,"end":124},"obj":"Chemical"}],"attributes":[{"id":"A45","pred":"tao:has_database_id","subj":"45","obj":"Gene:59272"},{"id":"A46","pred":"tao:has_database_id","subj":"46","obj":"MESH:D006493"},{"id":"A47","pred":"tao:has_database_id","subj":"47","obj":"Gene:43740568"},{"id":"A48","pred":"tao:has_database_id","subj":"48","obj":"MESH:D006493"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Both ACE2 and heparin can bind independently to spike protein in vitro, and a ternary complex can be generated using heparin as a scaffold."}
Covid19_manual_annotation_v2
{"project":"Covid19_manual_annotation_v2","denotations":[{"id":"45","span":{"begin":5,"end":9},"obj":"Gene"},{"id":"46","span":{"begin":14,"end":21},"obj":"Glycan"},{"id":"47","span":{"begin":48,"end":53},"obj":"Gene"},{"id":"48","span":{"begin":117,"end":124},"obj":"Glycan"},{"id":"T1","span":{"begin":62,"end":70},"obj":"Condition"},{"id":"T16","span":{"begin":78,"end":85},"obj":"Number"},{"id":"T20","span":{"begin":26,"end":30},"obj":"Phenomena"},{"id":"T21","span":{"begin":101,"end":110},"obj":"PositiveRegulation"},{"id":"T42","span":{"begin":26,"end":30},"obj":"Phenomena"},{"id":"T46","span":{"begin":86,"end":93},"obj":"Biological"},{"id":"T52","span":{"begin":5,"end":9},"obj":"Gene"},{"id":"T53","span":{"begin":14,"end":21},"obj":"Glycan"},{"id":"T54","span":{"begin":48,"end":53},"obj":"Gene"},{"id":"T6","span":{"begin":31,"end":44},"obj":"Condition"}],"relations":[{"id":"R17","pred":"has_status","subj":"T20","obj":"T1"},{"id":"R18","pred":"has_status","subj":"T42","obj":"T1"},{"id":"R24","pred":"is_a","subj":"47","obj":"T20"},{"id":"R27","pred":"is_a","subj":"47","obj":"T42"},{"id":"R65","pred":"of_a","subj":"T16","obj":"T46"},{"id":"R69","pred":"has_status","subj":"T20","obj":"T6"},{"id":"R70","pred":"has_status","subj":"T42","obj":"T6"},{"id":"R71","pred":"to","subj":"T20","obj":"45"},{"id":"R72","pred":"to","subj":"T42","obj":"46"},{"id":"R88","pred":"coreference","subj":"T46","obj":"T52"},{"id":"R89","pred":"coreference","subj":"T46","obj":"T53"},{"id":"R90","pred":"coreference","subj":"T46","obj":"T54"},{"id":"R91","pred":"is_a","subj":"T46","obj":"T21"},{"id":"R92","pred":"using","subj":"48","obj":"T21"},{"id":"R93","pred":"has_status","subj":"T21","obj":"T1"}],"attributes":[{"id":"A90","pred":"Memo","subj":"T42","obj":"MESH:D000076662"},{"id":"A48","pred":"tao:has_database_id","subj":"48","obj":"MESH:D006493"},{"id":"A104","pred":"tao:has_database_id","subj":"T52","obj":"Gene:59272"},{"id":"A46","pred":"tao:has_database_id","subj":"46","obj":"MESH:D006493"},{"id":"A47","pred":"tao:has_database_id","subj":"47","obj":"Gene:43740568"},{"id":"A106","pred":"tao:has_database_id","subj":"T54","obj":"Gene:43740568"},{"id":"A45","pred":"tao:has_database_id","subj":"45","obj":"Gene:59272"},{"id":"A105","pred":"tao:has_database_id","subj":"T53","obj":"MESH:D006493"},{"id":"A100","pred":"tao:has_database_id","subj":"T20","obj":"MESH:D053585"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"BioProject","uri":"https://www.ncbi.nlm.nih.gov/bioproject/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"},{"prefix":"HP","uri":"https://hpo.jax.org/app/browse/term/HP:"},{"prefix":"BioSample","uri":"https://www.ncbi.nlm.nih.gov/biosample/"}],"text":"Both ACE2 and heparin can bind independently to spike protein in vitro, and a ternary complex can be generated using heparin as a scaffold."}
Zoonoses
{"project":"Zoonoses","denotations":[{"id":"45","span":{"begin":5,"end":9},"obj":"Gene"},{"id":"46","span":{"begin":14,"end":21},"obj":"Glycan"},{"id":"47","span":{"begin":48,"end":53},"obj":"Gene"},{"id":"48","span":{"begin":117,"end":124},"obj":"Glycan"},{"id":"T1","span":{"begin":62,"end":70},"obj":"Condition"},{"id":"T16","span":{"begin":78,"end":85},"obj":"Number"},{"id":"T20","span":{"begin":26,"end":30},"obj":"Phenomena"},{"id":"T21","span":{"begin":101,"end":110},"obj":"PositiveRegulation"},{"id":"T42","span":{"begin":26,"end":30},"obj":"Phenomena"},{"id":"T46","span":{"begin":86,"end":93},"obj":"Biological"},{"id":"T52","span":{"begin":5,"end":9},"obj":"Gene"},{"id":"T53","span":{"begin":14,"end":21},"obj":"Glycan"},{"id":"T54","span":{"begin":48,"end":53},"obj":"Gene"},{"id":"T6","span":{"begin":31,"end":44},"obj":"Condition"}],"relations":[{"id":"R65","pred":"of_a","subj":"T16","obj":"T46"},{"id":"R71","pred":"to","subj":"T20","obj":"45"},{"id":"R72","pred":"to","subj":"T42","obj":"46"},{"id":"R69","pred":"has_status","subj":"T20","obj":"T6"},{"id":"R70","pred":"has_status","subj":"T42","obj":"T6"},{"id":"R88","pred":"coreference","subj":"T46","obj":"T52"},{"id":"R89","pred":"coreference","subj":"T46","obj":"T53"},{"id":"R90","pred":"coreference","subj":"T46","obj":"T54"},{"id":"R91","pred":"is_a","subj":"T46","obj":"T21"},{"id":"R92","pred":"using","subj":"48","obj":"T21"},{"id":"R93","pred":"has_status","subj":"T21","obj":"T1"},{"id":"R17","pred":"has_status","subj":"T20","obj":"T1"},{"id":"R18","pred":"has_status","subj":"T42","obj":"T1"},{"id":"R24","pred":"is_a","subj":"47","obj":"T20"},{"id":"R27","pred":"is_a","subj":"47","obj":"T42"}],"attributes":[{"id":"A113","pred":"Memo","subj":"T42","obj":"MESH:D054884"},{"id":"A48","pred":"tao:has_database_id","subj":"48","obj":"MESH:D006493"},{"id":"A45","pred":"tao:has_database_id","subj":"45","obj":"Gene:59272"},{"id":"A105","pred":"tao:has_database_id","subj":"T53","obj":"MESH:D006493"},{"id":"A100","pred":"tao:has_database_id","subj":"T20","obj":"MESH:D053585"},{"id":"A106","pred":"tao:has_database_id","subj":"T54","obj":"Gene:43740568"},{"id":"A46","pred":"tao:has_database_id","subj":"46","obj":"MESH:D006493"},{"id":"A47","pred":"tao:has_database_id","subj":"47","obj":"Gene:43740568"},{"id":"A104","pred":"tao:has_database_id","subj":"T52","obj":"Gene:59272"}],"text":"Both ACE2 and heparin can bind independently to spike protein in vitro, and a ternary complex can be generated using heparin as a scaffold."}
Inflammaging
{"project":"Inflammaging","denotations":[{"id":"T4","span":{"begin":0,"end":139},"obj":"Sentence"},{"id":"T4","span":{"begin":0,"end":139},"obj":"Sentence"}],"text":"Both ACE2 and heparin can bind independently to spike protein in vitro, and a ternary complex can be generated using heparin as a scaffold."}
Covid19_manual_annotation
{"project":"Covid19_manual_annotation","denotations":[{"id":"45","span":{"begin":5,"end":9},"obj":"Gene"},{"id":"46","span":{"begin":14,"end":21},"obj":"Biological"},{"id":"47","span":{"begin":48,"end":53},"obj":"Gene"},{"id":"48","span":{"begin":117,"end":124},"obj":"Biological"},{"id":"T1","span":{"begin":62,"end":70},"obj":"Condition"},{"id":"T16","span":{"begin":78,"end":93},"obj":"Structure"},{"id":"T20","span":{"begin":26,"end":30},"obj":"Bind"},{"id":"T21","span":{"begin":101,"end":110},"obj":"Produce"},{"id":"T6","span":{"begin":31,"end":44},"obj":"Condition"}],"relations":[{"id":"R34","pred":"is_a","subj":"46","obj":"T20"},{"id":"R35","pred":"of_a","subj":"T6","obj":"T20"},{"id":"R36","pred":"to","subj":"T20","obj":"47"},{"id":"R37","pred":"of_a","subj":"T1","obj":"T20"},{"id":"R33","pred":"is_a","subj":"45","obj":"T20"},{"id":"R38","pred":"is_a","subj":"T16","obj":"T21"},{"id":"R39","pred":"using","subj":"48","obj":"T21"}],"attributes":[{"id":"A45","pred":"tao:has_database_id","subj":"45","obj":"Gene:59272"},{"id":"A46","pred":"tao:has_database_id","subj":"46","obj":"MESH:D006493"},{"id":"A47","pred":"tao:has_database_id","subj":"47","obj":"Gene:43740568"},{"id":"A48","pred":"tao:has_database_id","subj":"48","obj":"MESH:D006493"}],"text":"Both ACE2 and heparin can bind independently to spike protein in vitro, and a ternary complex can be generated using heparin as a scaffold."}