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GlyCosmos15-Species

Id Subject Object Predicate Lexical cue db_id
2 0-5 Species denotes Human 9606
18 274-279 Species denotes human 9606

GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 60-72 Glycan_Motif denotes sialic acids https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY
T2 123-134 Glycan_Motif denotes sialic acid https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY
T3 327-338 Glycan_Motif denotes sialic acid https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY
T4 428-454 Glycan_Motif denotes 9-O-acetylated sialic acid https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G47325QT
T5 443-454 Glycan_Motif denotes sialic acid https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY
T6 532-558 Glycan_Motif denotes 9-O-acetylated sialic acid https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G47325QT
T7 547-558 Glycan_Motif denotes sialic acid https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY
T8 564-570 Glycan_Motif denotes Neu5Ac https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY
T9 822-828 Glycan_Motif denotes Neu5Ac https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY
T10 1036-1048 Glycan_Motif denotes sialic acids https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 60-72 https://glytoucan.org/Structures/Glycans/G81533KY denotes sialic acids
T2 123-134 https://glytoucan.org/Structures/Glycans/G81533KY denotes sialic acid
T3 327-338 https://glytoucan.org/Structures/Glycans/G81533KY denotes sialic acid
T4 428-454 https://glytoucan.org/Structures/Glycans/G47325QT denotes 9-O-acetylated sialic acid
T5 443-454 https://glytoucan.org/Structures/Glycans/G81533KY denotes sialic acid
T6 532-558 https://glytoucan.org/Structures/Glycans/G47325QT denotes 9-O-acetylated sialic acid
T7 547-558 https://glytoucan.org/Structures/Glycans/G81533KY denotes sialic acid
T8 564-570 https://glytoucan.org/Structures/Glycans/G81533KY denotes Neu5Ac
T9 822-828 https://glytoucan.org/Structures/Glycans/G81533KY denotes Neu5Ac
T10 1036-1048 https://glytoucan.org/Structures/Glycans/G81533KY denotes sialic acids

sentences

Id Subject Object Predicate Lexical cue
T1 0-90 Sentence denotes Human neuraminidases have reduced activity towards modified sialic acids on glycoproteins.
T2 91-224 Sentence denotes Multiple levels of diversity in sialic acid presentation can influence the substrate activity of sialosides for glycoside hydrolases.
T3 225-380 Sentence denotes Few reports have investigated the specificity of human neuraminidase (hNEU) activity towards modified sialic acid residues that can occur on glycoproteins.
T4 381-571 Sentence denotes Previously, we evaluated hNEU activity towards 9-O-acetylated sialic acid in glycolipid substrates and found that hNEU generally discriminated against 9-O-acetylated sialic acid over Neu5Ac.
T5 572-744 Sentence denotes Here, we have investigated the substrate specificity of hNEU enzymes for a glycoprotein substrate (bovine submaxillary mucin) containing 9-O-acetylated and Neu5Gc residues.
T6 745-915 Sentence denotes Using this model substrate, we observe a general trend for hNEU tolerance of Neu5Ac > Neu5Gc ≫ Neu5,9Ac2, consistent with our previous results with glycolipid substrates.
T7 916-1093 Sentence denotes These results expand our understanding of hNEU enzyme specificity and suggest that naturally occurring modifications of sialic acids can play a role in regulating hNEU activity.

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue image
T1 428-454 Glycan denotes 9-O-acetylated sialic acid https://api.glycosmos.org/wurcs2image/latest/png/binary/G47325QT
T2 532-558 Glycan denotes 9-O-acetylated sialic acid https://api.glycosmos.org/wurcs2image/latest/png/binary/G47325QT
T3 564-570 Glycan denotes Neu5Ac https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR
T4 822-828 Glycan denotes Neu5Ac https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR

Glycan-GlyCosmos

Id Subject Object Predicate Lexical cue image
T1 564-570 Glycan denotes Neu5Ac https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR
T2 822-828 Glycan denotes Neu5Ac https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-90 Sentence denotes Human neuraminidases have reduced activity towards modified sialic acids on glycoproteins.
T2 91-224 Sentence denotes Multiple levels of diversity in sialic acid presentation can influence the substrate activity of sialosides for glycoside hydrolases.
T3 225-380 Sentence denotes Few reports have investigated the specificity of human neuraminidase (hNEU) activity towards modified sialic acid residues that can occur on glycoproteins.
T4 381-571 Sentence denotes Previously, we evaluated hNEU activity towards 9-O-acetylated sialic acid in glycolipid substrates and found that hNEU generally discriminated against 9-O-acetylated sialic acid over Neu5Ac.
T5 572-744 Sentence denotes Here, we have investigated the substrate specificity of hNEU enzymes for a glycoprotein substrate (bovine submaxillary mucin) containing 9-O-acetylated and Neu5Gc residues.
T6 745-915 Sentence denotes Using this model substrate, we observe a general trend for hNEU tolerance of Neu5Ac > Neu5Gc ≫ Neu5,9Ac2, consistent with our previous results with glycolipid substrates.
T7 916-1093 Sentence denotes These results expand our understanding of hNEU enzyme specificity and suggest that naturally occurring modifications of sialic acids can play a role in regulating hNEU activity.

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 0-5 OrganismTaxon denotes Human 9606
T2 274-279 OrganismTaxon denotes human 9606
T3 671-677 OrganismTaxon denotes bovine 9913