> top > docs > PubMed:32763970 > annotations

PubMed:32763970 JSONTXT

Annnotations TAB JSON ListView MergeView

LitCovid-OGER-BB

Id Subject Object Predicate Lexical cue
T1 9-14 PR:000011271 denotes NLRP3
T2 28-38 GO:0042116 denotes activation
T3 39-49 GO:0070269 denotes pyroptosis
T4 66-83 CL:0009002 denotes inflammatory cell
T5 79-89 GO:0008219 denotes cell death
T6 94-103 PR:000002317 denotes caspase-8
T7 104-109 PR:000014024 denotes RIPK3
T8 117-128 NCBITaxon:11118 denotes coronavirus
T9 140-153 NCBITaxon:11118 denotes Coronaviruses
T10 285-309 GO:0010941 denotes regulation of cell death
T11 327-333 UBERON:0002405 denotes immune
T12 327-343 GO:0006955 denotes immune responses
T13 387-398 NCBITaxon:11118 denotes coronavirus
T14 450-457 GO:0065007 denotes control
T15 541-547 NCBITaxon:39107 denotes murine
T16 548-559 NCBITaxon:11118 denotes coronavirus
T17 560-565 NCBITaxon:10088 denotes mouse
T18 566-575 NCBITaxon:5690 denotes hepatitis
T19 576-581 NCBITaxon:10376 denotes virus
T20 583-586 NCBITaxon:11757 denotes MHV
T21 602-607 PR:000011271 denotes NLRP3
T22 625-642 CL:0009002 denotes inflammatory cell
T23 638-648 GO:0008219 denotes cell death
T24 685-690 PR:000011271 denotes NLRP3
T25 733-743 GO:0008219 denotes cell death
T26 756-767 PR:000029521 denotes gasdermin D
T27 807-817 GO:0008219 denotes cell death
T28 868-877 PR:000002317 denotes caspase-8
T29 883-937 PR:000014024 denotes receptor-interacting serine/threonine-protein kinase 3
T30 939-944 PR:000014024 denotes RIPK3
T31 955-972 CL:0009002 denotes inflammatory cell
T32 968-978 GO:0008219 denotes cell death
T33 985-996 NCBITaxon:11118 denotes coronavirus
T34 1052-1057 PR:000011271 denotes NLRP3
T35 1071-1081 GO:0002437 denotes activation
T36 1139-1150 NCBITaxon:11118 denotes coronavirus
T37 1251-1268 CL:0009002 denotes inflammatory cell
T38 1264-1274 GO:0008219 denotes cell death
T39 1289-1300 NCBITaxon:11118 denotes coronavirus
T40 1329-1334 PR:000011271 denotes NLRP3
T41 1360-1370 GO:0070269 denotes pyroptosis
T42 1481-1492 NCBITaxon:11118 denotes coronavirus

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T1 79-83 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T2 299-303 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T3 638-642 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T4 733-737 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T5 807-811 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T6 904-910 Body_part denotes serine http://purl.org/sig/ont/fma/fma82764
T7 911-920 Body_part denotes threonine http://purl.org/sig/ont/fma/fma82765
T8 921-928 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T9 968-972 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T10 1113-1122 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T11 1264-1268 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 129-138 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T2 174-193 Disease denotes zoonotic infections http://purl.obolibrary.org/obo/MONDO_0025481
T3 399-408 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T4 522-531 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T5 566-575 Disease denotes hepatitis http://purl.obolibrary.org/obo/MONDO_0002251
T6 997-1006 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T7 1151-1160 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T8 1301-1310 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1 28-38 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T2 79-83 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T3 299-303 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T4 560-565 http://purl.obolibrary.org/obo/CLO_0007836 denotes mouse
T5 576-581 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T6 588-597 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T7 638-642 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T8 733-737 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T9 807-811 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T10 830-831 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T11 968-972 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T12 1071-1081 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T13 1264-1268 http://purl.obolibrary.org/obo/GO_0005623 denotes cell

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T1 904-910 Chemical denotes serine http://purl.obolibrary.org/obo/CHEBI_17822
T2 911-920 Chemical denotes threonine http://purl.obolibrary.org/obo/CHEBI_26986
T3 921-928 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T1 566-575 Phenotype denotes hepatitis http://purl.obolibrary.org/obo/HP_0012115

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T1 9-38 http://purl.obolibrary.org/obo/GO_0044546 denotes NLRP3 inflammasome activation
T2 39-49 http://purl.obolibrary.org/obo/GO_0070269 denotes pyroptosis
T3 79-89 http://purl.obolibrary.org/obo/GO_0008219 denotes cell death
T4 285-309 http://purl.obolibrary.org/obo/GO_0010941 denotes regulation of cell death
T5 285-295 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T6 299-309 http://purl.obolibrary.org/obo/GO_0008219 denotes cell death
T7 327-343 http://purl.obolibrary.org/obo/GO_0006955 denotes immune responses
T8 638-648 http://purl.obolibrary.org/obo/GO_0008219 denotes cell death
T9 733-743 http://purl.obolibrary.org/obo/GO_0008219 denotes cell death
T10 807-817 http://purl.obolibrary.org/obo/GO_0008219 denotes cell death
T11 968-978 http://purl.obolibrary.org/obo/GO_0008219 denotes cell death
T12 1052-1081 http://purl.obolibrary.org/obo/GO_0044546 denotes NLRP3 inflammasome activation
T13 1264-1274 http://purl.obolibrary.org/obo/GO_0008219 denotes cell death
T14 1360-1370 http://purl.obolibrary.org/obo/GO_0070269 denotes pyroptosis

Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-139 Sentence denotes Impaired NLRP3 inflammasome activation/pyroptosis leads to robust inflammatory cell death via caspase-8/RIPK3 during coronavirus infection.
T2 140-275 Sentence denotes Coronaviruses have caused several zoonotic infections in the past two decades, leading to significant morbidity and mortality globally.
T3 276-496 Sentence denotes Balanced regulation of cell death and inflammatory immune responses is essential to promote protection against coronavirus infection; however, the underlying mechanisms that control these processes remain to be resolved.
T4 497-675 Sentence denotes Here we demonstrate that infection with the murine coronavirus mouse hepatitis virus (MHV) activated the NLRP3 inflammasome and inflammatory cell death in the form of PANoptosis.
T5 676-1007 Sentence denotes Deleting NLRP3 inflammasome components or the downstream cell death executioner gasdermin D (GSDMD) led to an initial reduction in cell death followed by a robust increase in the incidence of caspase-8- and receptor-interacting serine/threonine-protein kinase 3 (RIPK3)-mediated inflammatory cell death after coronavirus infection.
T6 1008-1082 Sentence denotes Additionally, loss of GSDMD promoted robust NLRP3 inflammasome activation.
T7 1083-1216 Sentence denotes Moreover, the amounts of some cytokines released during coronavirus infection were significantly altered due to the absence of GSDMD.
T8 1217-1418 Sentence denotes Altogether our findings show that inflammatory cell death is induced by coronavirus infection and that impaired NLRP3 inflammasome function or pyroptosis can lead to negative consequences for the host.
T9 1419-1509 Sentence denotes These findings may have important implications for studies of coronavirus-induced disease.
T1 0-139 Sentence denotes Impaired NLRP3 inflammasome activation/pyroptosis leads to robust inflammatory cell death via caspase-8/RIPK3 during coronavirus infection.
T2 140-275 Sentence denotes Coronaviruses have caused several zoonotic infections in the past two decades, leading to significant morbidity and mortality globally.
T3 276-496 Sentence denotes Balanced regulation of cell death and inflammatory immune responses is essential to promote protection against coronavirus infection; however, the underlying mechanisms that control these processes remain to be resolved.
T4 497-675 Sentence denotes Here we demonstrate that infection with the murine coronavirus mouse hepatitis virus (MHV) activated the NLRP3 inflammasome and inflammatory cell death in the form of PANoptosis.
T5 676-1007 Sentence denotes Deleting NLRP3 inflammasome components or the downstream cell death executioner gasdermin D (GSDMD) led to an initial reduction in cell death followed by a robust increase in the incidence of caspase-8- and receptor-interacting serine/threonine-protein kinase 3 (RIPK3)-mediated inflammatory cell death after coronavirus infection.
T6 1008-1082 Sentence denotes Additionally, loss of GSDMD promoted robust NLRP3 inflammasome activation.
T7 1083-1216 Sentence denotes Moreover, the amounts of some cytokines released during coronavirus infection were significantly altered due to the absence of GSDMD.
T8 1217-1418 Sentence denotes Altogether our findings show that inflammatory cell death is induced by coronavirus infection and that impaired NLRP3 inflammasome function or pyroptosis can lead to negative consequences for the host.
T9 1419-1509 Sentence denotes These findings may have important implications for studies of coronavirus-induced disease.

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T1 0-139 Sentence denotes Impaired NLRP3 inflammasome activation/pyroptosis leads to robust inflammatory cell death via caspase-8/RIPK3 during coronavirus infection.
T2 140-275 Sentence denotes Coronaviruses have caused several zoonotic infections in the past two decades, leading to significant morbidity and mortality globally.
T3 276-496 Sentence denotes Balanced regulation of cell death and inflammatory immune responses is essential to promote protection against coronavirus infection; however, the underlying mechanisms that control these processes remain to be resolved.
T4 497-675 Sentence denotes Here we demonstrate that infection with the murine coronavirus mouse hepatitis virus (MHV) activated the NLRP3 inflammasome and inflammatory cell death in the form of PANoptosis.
T5 676-1007 Sentence denotes Deleting NLRP3 inflammasome components or the downstream cell death executioner gasdermin D (GSDMD) led to an initial reduction in cell death followed by a robust increase in the incidence of caspase-8- and receptor-interacting serine/threonine-protein kinase 3 (RIPK3)-mediated inflammatory cell death after coronavirus infection.
T6 1008-1082 Sentence denotes Additionally, loss of GSDMD promoted robust NLRP3 inflammasome activation.
T7 1083-1216 Sentence denotes Moreover, the amounts of some cytokines released during coronavirus infection were significantly altered due to the absence of GSDMD.
T8 1217-1418 Sentence denotes Altogether our findings show that inflammatory cell death is induced by coronavirus infection and that impaired NLRP3 inflammasome function or pyroptosis can lead to negative consequences for the host.
T9 1419-1509 Sentence denotes These findings may have important implications for studies of coronavirus-induced disease.

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
2 9-14 Gene denotes NLRP3 Gene:114548
3 117-138 Disease denotes coronavirus infection MESH:D018352
21 140-153 Species denotes Coronaviruses Tax:11118
22 174-193 Disease denotes zoonotic infections MESH:D015047
23 256-265 Disease denotes mortality MESH:D003643
24 387-408 Disease denotes coronavirus infection MESH:D018352
25 522-531 Disease denotes infection MESH:D007239
26 541-559 Species denotes murine coronavirus Tax:694005
27 560-581 Species denotes mouse hepatitis virus Tax:11138
28 583-586 Species denotes MHV Tax:11138
29 602-607 Gene denotes NLRP3 Gene:114548
30 685-690 Gene denotes NLRP3 Gene:114548
31 904-910 Chemical denotes serine MESH:D012694
32 985-1006 Disease denotes coronavirus infection MESH:D018352
33 1052-1057 Gene denotes NLRP3 Gene:114548
34 1139-1160 Disease denotes coronavirus infection MESH:D018352
35 1289-1310 Disease denotes coronavirus infection MESH:D018352
36 1329-1334 Gene denotes NLRP3 Gene:114548
37 1481-1508 Disease denotes coronavirus-induced disease MESH:D018352

LitCovid_AGAC_only

Id Subject Object Predicate Lexical cue
p86822s0 676-684 Var denotes Deleting
p86822s1 685-690 Gene denotes NLRP3
p86822s21 807-817 CPA denotes cell death
p86822s47 938-945 Gene denotes (RIPK3)
p86823s2 1022-1026 Var denotes loss

sentences

Id Subject Object Predicate Lexical cue
T1 0-139 Sentence denotes Impaired NLRP3 inflammasome activation/pyroptosis leads to robust inflammatory cell death via caspase-8/RIPK3 during coronavirus infection.
T2 140-275 Sentence denotes Coronaviruses have caused several zoonotic infections in the past two decades, leading to significant morbidity and mortality globally.
T3 276-496 Sentence denotes Balanced regulation of cell death and inflammatory immune responses is essential to promote protection against coronavirus infection; however, the underlying mechanisms that control these processes remain to be resolved.
T4 497-675 Sentence denotes Here we demonstrate that infection with the murine coronavirus mouse hepatitis virus (MHV) activated the NLRP3 inflammasome and inflammatory cell death in the form of PANoptosis.
T5 676-1007 Sentence denotes Deleting NLRP3 inflammasome components or the downstream cell death executioner gasdermin D (GSDMD) led to an initial reduction in cell death followed by a robust increase in the incidence of caspase-8- and receptor-interacting serine/threonine-protein kinase 3 (RIPK3)-mediated inflammatory cell death after coronavirus infection.
T6 1008-1082 Sentence denotes Additionally, loss of GSDMD promoted robust NLRP3 inflammasome activation.
T7 1083-1216 Sentence denotes Moreover, the amounts of some cytokines released during coronavirus infection were significantly altered due to the absence of GSDMD.
T8 1217-1418 Sentence denotes Altogether our findings show that inflammatory cell death is induced by coronavirus infection and that impaired NLRP3 inflammasome function or pyroptosis can lead to negative consequences for the host.
T9 1419-1509 Sentence denotes These findings may have important implications for studies of coronavirus-induced disease.

HP-phenotype

Id Subject Object Predicate Lexical cue hp_id
T1 566-575 Phenotype denotes hepatitis HP:0012115

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 129-138 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T2 174-193 Disease denotes zoonotic infections http://purl.obolibrary.org/obo/MONDO_0025481
T3 399-408 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T4 522-531 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T5 566-575 Disease denotes hepatitis http://purl.obolibrary.org/obo/MONDO_0002251
T6 997-1006 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T7 1151-1160 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T8 1301-1310 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 541-559 OrganismTaxon denotes murine coronavirus 694005
T2 560-565 OrganismTaxon denotes mouse 10088|10090
T4 566-581 OrganismTaxon denotes hepatitis virus 10407

CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 66-83 Cell denotes inflammatory cell http://purl.obolibrary.org/obo/CL:0009002
T2 625-642 Cell denotes inflammatory cell http://purl.obolibrary.org/obo/CL:0009002
T3 955-972 Cell denotes inflammatory cell http://purl.obolibrary.org/obo/CL:0009002
T4 1251-1268 Cell denotes inflammatory cell http://purl.obolibrary.org/obo/CL:0009002