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LitCovid-OGER-BB

Id Subject Object Predicate Lexical cue
T1 33-38 CHEBI:67079 denotes anti-
T2 33-38 CHEBI:67079 denotes anti-
T3 79-87 SP_7 denotes COVID-19
T4 401-407 UBERON:0007023 denotes adults
T5 446-454 SP_7 denotes COVID-19
T6 578-585 GO:0007612 denotes learned
T7 730-735 GO:0016265 denotes death
T8 870-880 CL:0000542 denotes lymphocyte
T9 914-919 CHEBI:67079 denotes anti-
T10 914-919 CHEBI:67079 denotes anti-
T11 929-935 CHEBI:67079 denotes agents
T12 929-935 CHEBI:67079 denotes agents
T13 941-950 CHEBI:31781 denotes lopinavir
T14 941-950 CHEBI:31781 denotes lopinavir
T15 941-950 DG_23 denotes lopinavir
T16 951-960 DG_30 denotes ritonavir
T17 969-981 CHEBI:2955 denotes azithromycin
T18 969-981 CHEBI:2955 denotes azithromycin
T19 969-981 DG_6 denotes azithromycin
T20 1017-1035 CHEBI:5801 denotes hydroxychloroquine
T21 1017-1035 CHEBI:5801 denotes hydroxychloroquine
T22 1017-1035 DG_20 denotes hydroxychloroquine
T23 1218-1227 UBERON:0002048 denotes Pulmonary
T24 1597-1608 NCBITaxon:1 denotes individuals
T25 1610-1620 CL:0000542 denotes lymphocyte
T26 1811-1820 UBERON:0002048 denotes pulmonary
T27 1880-1901 CHEBI:67079 denotes anti-infective agents
T28 1880-1901 CHEBI:67079 denotes anti-infective agents

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T1 870-880 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T2 1610-1620 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 79-87 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T2 446-454 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1 424-425 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T2 444-445 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T3 597-600 http://purl.obolibrary.org/obo/PR_000001343 denotes Aim
T4 868-869 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T5 1045-1047 http://purl.obolibrary.org/obo/CLO_0001407 denotes 52
T6 1081-1082 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T7 1451-1452 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T8 1687-1688 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T9 1788-1789 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T10 1853-1854 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T1 33-54 Chemical denotes anti-infective agents http://purl.obolibrary.org/obo/CHEBI_35441
T2 147-168 Chemical denotes anti-infective agents http://purl.obolibrary.org/obo/CHEBI_35441
T3 426-434 Chemical denotes medicine http://purl.obolibrary.org/obo/CHEBI_23888
T4 914-935 Chemical denotes anti-infective agents http://purl.obolibrary.org/obo/CHEBI_35441
T5 941-960 Chemical denotes lopinavir-ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T6 941-950 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T7 951-960 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T8 969-981 Chemical denotes azithromycin http://purl.obolibrary.org/obo/CHEBI_2955
T9 983-986 Chemical denotes AZI http://purl.obolibrary.org/obo/CHEBI_2955
T10 999-1002 Chemical denotes AZI http://purl.obolibrary.org/obo/CHEBI_2955
T11 1017-1035 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T12 1302-1308 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T13 1362-1365 Chemical denotes AZI http://purl.obolibrary.org/obo/CHEBI_2955
T14 1508-1511 Chemical denotes AZI http://purl.obolibrary.org/obo/CHEBI_2955
T15 1833-1839 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T16 1880-1901 Chemical denotes anti-infective agents http://purl.obolibrary.org/obo/CHEBI_35441

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T1 0-120 Sentence denotes Impact of medical care including anti-infective agents use on the prognosis of COVID-19 hospitalized patients over time.
T2 121-134 Sentence denotes INTRODUCTION:
T3 135-206 Sentence denotes Interest of anti-infective agents in COVD-19 showed discrepant results.
T4 207-307 Sentence denotes However, there is no evaluation about the impact in changes of practices on the prognosis over time.
T5 308-316 Sentence denotes METHODS:
T6 317-455 Sentence denotes Single center, retrospective study, conducted from March 5th to April 25th 2020, in adults hospitalized in a medicine ward for a COVID-19.
T7 456-596 Sentence denotes Patient characteristics were compared between 2 periods (before/after March 19th) considering French guidelines issued by learned societies.
T8 597-736 Sentence denotes Aim of the study was to evaluate how medical care impacted unfavorable outcome, namely admission in intensive care unit (ICU) and/or death.
T9 737-745 Sentence denotes RESULTS:
T10 746-896 Sentence denotes One hundred thirty-two patients were admitted, mean age was 59.0 ± 16.3 years, mean CRP level was 84.0±71.1 mg/L, 46% had a lymphocyte count<1000/mm3.
T11 897-1049 Sentence denotes When prescribed, anti-infective agents were lopinavir-ritonavir (n=12), azithromycin (AZI) (n=28) and AZI combined with hydroxychloroquine (HCQ) (n=52).
T12 1050-1149 Sentence denotes Between the 2 periods we noted a significant decrease of ICU admission, from 43% to 12% (p<0.0001).
T13 1150-1217 Sentence denotes Delays until transfer in ICU were similar between periods (p=0.86).
T14 1218-1421 Sentence denotes Pulmonary CT-scan were significantly more performed (from 50% to 90%, p<0.0001), as oxygen-dependency (53% vs 80%, p=0.001) and prescription of AZI±HCQ (from 25% to 76%, p<0.0001) were greater over time.
T15 1422-1647 Sentence denotes Multivariate analyses showed a reduction of unfavorable outcome in patients receiving AZI±HCQ (HR=0.45, 95%IC [0.21-0.97], p=0.04), especially among an identified category of individuals (lymphocyte≥1000/mm3 or CRP≥100 mg/L).
T16 1648-1659 Sentence denotes CONCLUSION:
T17 1660-1902 Sentence denotes The present study revealed a significant decrease of admission in ICU over time probably related to multiple factors, including a better indication of pulmonary CT-scan, of oxygen therapy, and a suitable prescription of anti-infective agents.