> top > docs > PubMed:32734353 > annotations

PubMed:32734353 JSONTXT

Annnotations TAB JSON ListView MergeView

LitCovid-OGER-BB

Id Subject Object Predicate Lexical cue
T1 16-28 UBERON:0001016 denotes neurological
T2 42-52 SP_7 denotes SARS-CoV-2
T3 96-102 UBERON:0002405 denotes immune
T4 112-124 UBERON:0001016 denotes neurological
T5 155-200 SP_10 denotes severe acute respiratory syndrome coronavirus
T6 168-179 UBERON:0001004 denotes respiratory
T7 202-212 SP_7 denotes SARS-CoV-2
T8 304-315 NCBITaxon:11118 denotes coronavirus
T9 330-338 SP_7 denotes COVID-19
T10 354-366 UBERON:0001016 denotes neurological
T11 404-412 SP_7 denotes COVID-19
T12 427-439 UBERON:0001016 denotes neurological
T13 532-544 UBERON:0001016 denotes neurological
T14 599-611 UBERON:0001016 denotes Neurological
T15 735-740 UBERON:0001977 denotes Serum
T16 746-758 CHEBI:28892 denotes gangliosides
T17 746-758 CHEBI:28892 denotes gangliosides
T18 759-769 GO:0042571 denotes antibodies
T19 829-837 SP_7 denotes COVID-19
T20 924-936 UBERON:0001016 denotes neurological
T21 1062-1073 CL:0000542 denotes lymphocytic
T22 1113-1141 PR:000025842 denotes contactin-associated protein
T23 1150-1156 PR:000005673 denotes Caspr2
T24 1158-1166 GO:0042571 denotes antibody
T25 1226-1231 UBERON:0001977 denotes serum
T26 1251-1261 GO:0042571 denotes antibodies
T27 1406-1415 UBERON:0002298 denotes brainstem
T28 1455-1465 SP_7 denotes SARS-CoV-2
T29 1512-1522 SP_7 denotes SARS-Cov-2
T30 1546-1558 UBERON:0001016 denotes neurological
T31 1579-1590 GO:0006909 denotes pleocytosis
T32 1674-1678 PR:B9DHD3 denotes GD1b
T33 1688-1694 PR:000005673 denotes Caspr2
T34 1695-1709 GO:0042571 denotes autoantibodies
T35 1770-1780 SP_7 denotes SARS-CoV-2

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T1 288-291 Body_part denotes CSF http://purl.org/sig/ont/fma/fma20935
T2 679-682 Body_part denotes CSF http://purl.org/sig/ont/fma/fma20935
T3 735-740 Body_part denotes Serum http://purl.org/sig/ont/fma/fma63083
T4 746-758 Body_part denotes gangliosides http://purl.org/sig/ont/fma/fma82816
T5 1006-1009 Body_part denotes CSF http://purl.org/sig/ont/fma/fma20935
T6 1062-1073 Body_part denotes lymphocytic http://purl.org/sig/ont/fma/fma62863
T7 1134-1141 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T8 1158-1166 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T9 1226-1231 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T10 1406-1415 Body_part denotes brainstem http://purl.org/sig/ont/fma/fma79876
T11 1443-1446 Body_part denotes CSF http://purl.org/sig/ont/fma/fma20935
T12 1575-1578 Body_part denotes CSF http://purl.org/sig/ont/fma/fma20935

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 735-740 Body_part denotes Serum http://purl.obolibrary.org/obo/UBERON_0001977
T2 1226-1231 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T3 1406-1415 Body_part denotes brainstem http://purl.obolibrary.org/obo/UBERON_0002298

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 42-50 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T2 155-188 Disease denotes severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T3 202-210 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T4 214-223 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T5 304-328 Disease denotes coronavirus disease 2019 http://purl.obolibrary.org/obo/MONDO_0100096
T6 330-338 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T7 404-412 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T8 475-482 Disease denotes anosmia http://purl.obolibrary.org/obo/MONDO_0010528
T9 548-569 Disease denotes psychiatric disorders http://purl.obolibrary.org/obo/MONDO_0002025
T10 829-837 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T11 1167-1179 Disease denotes encephalitis http://purl.obolibrary.org/obo/MONDO_0019956
T12 1357-1375 Disease denotes cranial neuropathy http://purl.obolibrary.org/obo/MONDO_0003569
T13 1365-1375 Disease denotes neuropathy http://purl.obolibrary.org/obo/MONDO_0005244
T14 1416-1428 Disease denotes encephalitis http://purl.obolibrary.org/obo/MONDO_0019956
T15 1433-1441 Disease denotes delirium http://purl.obolibrary.org/obo/MONDO_0045057
T16 1455-1463 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T17 1512-1516 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T18 1619-1647 Disease denotes post-infectious encephalitis http://purl.obolibrary.org/obo/MONDO_0020068
T19 1624-1647 Disease denotes infectious encephalitis http://purl.obolibrary.org/obo/MONDO_0020067
T20 1624-1634 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T21 1635-1647 Disease denotes encephalitis http://purl.obolibrary.org/obo/MONDO_0019956
T22 1770-1778 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1 775-781 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T1 746-758 Chemical denotes gangliosides http://purl.obolibrary.org/obo/CHEBI_28892
T2 1134-1141 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T3 1246-1250 Chemical denotes GD1b http://purl.obolibrary.org/obo/CHEBI_28175
T4 1674-1678 Chemical denotes GD1b http://purl.obolibrary.org/obo/CHEBI_28175

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T1 475-482 Phenotype denotes anosmia http://purl.obolibrary.org/obo/HP_0000458
T2 501-509 Phenotype denotes headache http://purl.obolibrary.org/obo/HP_0002315
T3 548-569 Phenotype denotes psychiatric disorders http://purl.obolibrary.org/obo/HP_0000708
T4 1167-1179 Phenotype denotes encephalitis http://purl.obolibrary.org/obo/HP_0002383
T5 1365-1375 Phenotype denotes neuropathy http://purl.obolibrary.org/obo/HP_0009830
T6 1416-1428 Phenotype denotes encephalitis http://purl.obolibrary.org/obo/HP_0002383
T7 1433-1441 Phenotype denotes delirium http://purl.obolibrary.org/obo/HP_0031258
T8 1575-1590 Phenotype denotes CSF pleocytosis http://purl.obolibrary.org/obo/HP_0012229
T9 1635-1647 Phenotype denotes encephalitis http://purl.obolibrary.org/obo/HP_0002383
T10 1799-1811 Phenotype denotes autoimmunity http://purl.obolibrary.org/obo/HP_0002960

LitCovid-PD-GlycoEpitope

Id Subject Object Predicate Lexical cue glyco_epitope_db_id
T1 1241-1250 GlycoEpitope denotes anti-GD1b http://www.glycoepitope.jp/epitopes/AN0403
T2 1246-1250 GlycoEpitope denotes GD1b http://www.glycoepitope.jp/epitopes/EP0059
T3 1669-1678 GlycoEpitope denotes Anti-GD1b http://www.glycoepitope.jp/epitopes/AN0403
T4 1674-1678 GlycoEpitope denotes GD1b http://www.glycoepitope.jp/epitopes/EP0059

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
2 42-61 Disease denotes SARS-CoV-2-infected MESH:C000657245
3 62-70 Species denotes patients Tax:9606
38 155-200 Species denotes severe acute respiratory syndrome coronavirus Tax:694009
39 202-212 Species denotes SARS-CoV-2 Tax:2697049
40 214-223 Disease denotes infection MESH:D007239
41 304-328 Disease denotes coronavirus disease 2019 MESH:C000657245
42 330-338 Disease denotes COVID-19 MESH:C000657245
43 340-348 Species denotes patients Tax:9606
44 404-412 Disease denotes COVID-19 MESH:C000657245
45 413-421 Species denotes patients Tax:9606
46 501-509 Disease denotes headache MESH:D006261
47 532-569 Disease denotes neurological or psychiatric disorders MESH:D001523
48 645-653 Species denotes patients Tax:9606
49 746-758 Chemical denotes gangliosides MESH:D005732
50 829-837 Disease denotes COVID-19 MESH:C000657245
51 904-912 Species denotes patients Tax:9606
52 1042-1050 Species denotes patients Tax:9606
53 1062-1085 Disease denotes lymphocytic pleocytosis MESH:D007964
54 1091-1099 Species denotes patients Tax:9606
55 1150-1156 Gene denotes Caspr2 Gene:26047
56 1167-1179 Disease denotes encephalitis MESH:D004660
57 1191-1214 Disease denotes meningo-polyradiculitis MESH:D011128
58 1281-1289 Species denotes patients Tax:9606
59 1357-1375 Disease denotes cranial neuropathy MESH:D003389
60 1381-1404 Disease denotes meningo-polyradiculitis MESH:D011128
61 1416-1428 Disease denotes encephalitis MESH:D004660
62 1433-1441 Disease denotes delirium MESH:D003693
63 1455-1465 Species denotes SARS-CoV-2 Tax:2697049
64 1486-1494 Species denotes patients Tax:9606
65 1512-1531 Disease denotes SARS-Cov-2 infected MESH:C000657245
66 1532-1540 Species denotes patients Tax:9606
67 1575-1590 Disease denotes CSF pleocytosis MESH:D007964
68 1635-1647 Disease denotes encephalitis MESH:D004660
69 1652-1667 Disease denotes polyradiculitis MESH:D011128
70 1688-1694 Gene denotes Caspr2 Gene:26047
71 1770-1780 Species denotes SARS-CoV-2 Tax:2697049

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T1 0-71 Sentence denotes Immune-mediated neurological syndromes in SARS-CoV-2-infected patients.
T2 72-83 Sentence denotes BACKGROUND:
T3 84-235 Sentence denotes Evidence of immune-mediated neurological syndromes associated with the severe acute respiratory syndrome coronavirus (SARS-CoV-2) infection is limited.
T4 236-382 Sentence denotes We therefore investigated clinical, serological and CSF features of coronavirus disease 2019 (COVID-19) patients with neurological manifestations.
T5 383-391 Sentence denotes METHODS:
T6 392-598 Sentence denotes Consecutive COVID-19 patients with neurological manifestations other than isolated anosmia and/or non-severe headache, and with no previous neurological or psychiatric disorders were prospectively included.
T7 599-734 Sentence denotes Neurological examination was performed in all patients and lumbar puncture with CSF examination was performed when not contraindicated.
T8 735-808 Sentence denotes Serum anti-gangliosides antibodies were tested when clinically indicated.
T9 809-817 Sentence denotes RESULTS:
T10 818-1005 Sentence denotes Of the 349 COVID-19 admitted to our center between March 23rd and April 24th 2020, 15 patients (4.3%) had neurological manifestations and fulfilled the study inclusion/exclusion criteria.
T11 1006-1100 Sentence denotes CSF examination was available in 13 patients and showed lymphocytic pleocytosis in 2 patients:
T12 1101-1215 Sentence denotes 1 with anti-contactin-associated protein 2 (anti-Caspr2) antibody encephalitis and 1 with meningo-polyradiculitis.
T13 1216-1442 Sentence denotes Increased serum titer of anti-GD1b antibodies was found in three patients and was associated with variable clinical presentations, including cranial neuropathy with meningo-polyradiculitis, brainstem encephalitis and delirium.
T14 1443-1495 Sentence denotes CSF PCR for SARS-CoV-2 was negative in all patients.
T15 1496-1508 Sentence denotes CONCLUSIONS:
T16 1509-1668 Sentence denotes In SARS-Cov-2 infected patients with neurological manifestations, CSF pleocytosis is associated with para- or post-infectious encephalitis and polyradiculitis.
T17 1669-1812 Sentence denotes Anti-GD1b and anti-Caspr2 autoantibodies can be identified in certain cases, raising the question of SARS-CoV-2-induced secondary autoimmunity.