PubMed:32712670 / 4702-5215 JSONTXT

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LitCovid-OGER-BB

Id Subject Object Predicate Lexical cue
T156 81-90 CHEBI:31781 denotes lopinavir
T157 81-90 DG_23 denotes lopinavir
T158 81-90 CHEBI:31781 denotes lopinavir
T159 98-107 GO:0007565 denotes pregnancy
T160 126-135 CHEBI:31781 denotes lopinavir
T161 126-135 DG_23 denotes lopinavir
T162 126-135 CHEBI:31781 denotes lopinavir
T163 197-206 DG_13 denotes darunavir
T164 256-265 GO:0007565 denotes pregnancy
T165 299-307 SP_7 denotes COVID-19
T166 318-327 CHEBI:31781 denotes lopinavir
T167 318-327 DG_23 denotes lopinavir
T168 318-327 CHEBI:31781 denotes lopinavir
T169 345-349 CHEBI:23888 denotes drug
T170 345-349 CHEBI:23888 denotes drug
T171 493-504 UBERON:0001004 denotes respiratory

Inflammaging

Id Subject Object Predicate Lexical cue
T38 0-513 Sentence denotes Our results highlight the need for reconsidering current guidelines recommending lopinavir use in pregnancy and indicate that lopinavir should be avoided especially in the first trimester, whereas darunavir is safe to use and should be the preferred PI in pregnancy.Further, in current times of the COVID-19 pandemic, lopinavir is among the top drug candidates which are being repurposed for inclusion in clinical trials world-over, to assess their therapeutic potential against the dangerous respiratory disease.
T38 0-513 Sentence denotes Our results highlight the need for reconsidering current guidelines recommending lopinavir use in pregnancy and indicate that lopinavir should be avoided especially in the first trimester, whereas darunavir is safe to use and should be the preferred PI in pregnancy.Further, in current times of the COVID-19 pandemic, lopinavir is among the top drug candidates which are being repurposed for inclusion in clinical trials world-over, to assess their therapeutic potential against the dangerous respiratory disease.