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LitCovid-OGER-BB

Id Subject Object Predicate Lexical cue
T1 0-8 UBERON:0004877 denotes Visceral
T2 94-102 SP_7 denotes COVID-19
T3 181-189 SP_7 denotes COVID-19
T4 461-469 SP_7 denotes COVID-19
T5 482-491 UBERON:0007808 denotes abdominal
T6 492-495 UBERON:0001013 denotes fat
T7 570-575 UBERON:0001443 denotes chest
T8 756-766 SP_7 denotes SARS-Cov-2
T9 783-788 UBERON:0001443 denotes chest
T10 939-947 UBERON:0004877 denotes Visceral
T11 953-956 UBERON:0004044 denotes VAT
T12 1136-1148 UBERON:0005169 denotes interstitial
T13 1185-1189 UBERON:0002048 denotes Lung
T14 1240-1251 CL:0000542 denotes lymphocytes
T15 1283-1292 UBERON:0007808 denotes abdominal
T16 1293-1296 UBERON:0001013 denotes fat
T17 1308-1311 UBERON:0001348 denotes VAT
T18 1686-1694 SP_7 denotes COVID-19

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T1 422-426 Body_part denotes body http://purl.org/sig/ont/fma/fma256135
T2 511-515 Body_part denotes body http://purl.org/sig/ont/fma/fma256135
T3 570-575 Body_part denotes chest http://purl.org/sig/ont/fma/fma9576
T4 783-788 Body_part denotes chest http://purl.org/sig/ont/fma/fma9576
T5 1185-1189 Body_part denotes Lung http://purl.org/sig/ont/fma/fma7195
T6 1240-1251 Body_part denotes lymphocytes http://purl.org/sig/ont/fma/fma62863

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 0-12 Body_part denotes Visceral fat http://purl.obolibrary.org/obo/UBERON_0035818
T2 570-575 Body_part denotes chest http://purl.obolibrary.org/obo/UBERON_0001443
T3 783-788 Body_part denotes chest http://purl.obolibrary.org/obo/UBERON_0001443
T4 939-951 Body_part denotes Visceral fat http://purl.obolibrary.org/obo/UBERON_0035818
T5 953-956 Body_part denotes VAT http://purl.obolibrary.org/obo/UBERON_0035818
T6 1185-1189 Body_part denotes Lung http://purl.obolibrary.org/obo/UBERON_0002048
T7 1308-1311 Body_part denotes VAT http://purl.obolibrary.org/obo/UBERON_0035818
T8 1445-1448 Body_part denotes VAT http://purl.obolibrary.org/obo/UBERON_0035818
T9 1626-1629 Body_part denotes VAT http://purl.obolibrary.org/obo/UBERON_0035818

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 94-102 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T2 116-123 Disease denotes Obesity http://purl.obolibrary.org/obo/MONDO_0011122
T3 181-189 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T4 461-469 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T5 756-760 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T6 1062-1074 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T7 1149-1158 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T8 1206-1209 Disease denotes LSS http://purl.obolibrary.org/obo/MONDO_0007615
T9 1272-1275 Disease denotes LSS http://purl.obolibrary.org/obo/MONDO_0007615
T10 1437-1440 Disease denotes LSS http://purl.obolibrary.org/obo/MONDO_0007615
T11 1686-1694 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1 9-12 http://purl.obolibrary.org/obo/UBERON_0001013 denotes fat
T2 151-152 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T3 386-391 http://purl.obolibrary.org/obo/CLO_0009985 denotes focus
T4 427-430 http://purl.obolibrary.org/obo/UBERON_0001013 denotes fat
T5 432-435 http://purl.obolibrary.org/obo/PR_000001343 denotes Aim
T6 492-495 http://purl.obolibrary.org/obo/UBERON_0001013 denotes fat
T7 499-500 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T8 568-569 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T9 570-575 http://www.ebi.ac.uk/efo/EFO_0000965 denotes chest
T10 736-742 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T11 781-782 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T12 783-788 http://www.ebi.ac.uk/efo/EFO_0000965 denotes chest
T13 908-912 http://purl.obolibrary.org/obo/UBERON_0003101 denotes male
T14 908-912 http://www.ebi.ac.uk/efo/EFO_0000970 denotes male
T15 948-951 http://purl.obolibrary.org/obo/UBERON_0001013 denotes fat
T16 1183-1184 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T17 1185-1189 http://purl.obolibrary.org/obo/UBERON_0002048 denotes Lung
T18 1185-1189 http://www.ebi.ac.uk/efo/EFO_0000934 denotes Lung
T19 1293-1296 http://purl.obolibrary.org/obo/UBERON_0001013 denotes fat
T20 1331-1332 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T21 1401-1402 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T22 1633-1634 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T1 908-912 Chemical denotes male http://purl.obolibrary.org/obo/CHEBI_30780

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T1 1062-1074 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
2 80-88 Species denotes Patients Tax:9606
3 94-102 Disease denotes COVID-19 MESH:C000657245
17 181-189 Disease denotes COVID-19 MESH:C000657245
18 461-469 Disease denotes COVID-19 MESH:C000657245
19 548-556 Species denotes patients Tax:9606
20 594-602 Species denotes Patients Tax:9606
21 756-766 Species denotes SARS-Cov-2 Tax:2697049
22 878-886 Species denotes patients Tax:9606
23 986-994 Species denotes patients Tax:9606
24 1062-1074 Disease denotes inflammation MESH:D007249
25 1083-1094 Gene denotes CRP and LDH Gene:1401
26 1149-1158 Disease denotes pneumonia MESH:D011014
27 1253-1256 Gene denotes CRP Gene:1401
28 1672-1680 Species denotes patients Tax:9606
29 1686-1694 Disease denotes COVID-19 MESH:C000657245

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T1 116-123 Phenotype denotes Obesity http://purl.obolibrary.org/obo/HP_0001513
T2 1149-1158 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T1 0-103 Sentence denotes Visceral fat shows the strongest association with the need of intensive Care in Patients with COVID-19.
T2 104-115 Sentence denotes BACKGROUND:
T3 116-227 Sentence denotes Obesity was recently identified as a major risk factor for worse COVID-19 severity, especially among the young.
T4 228-359 Sentence denotes The reason why its impact seems to be less pronounced in the elderly may be due to the concomitant presence of other comorbidities.
T5 360-431 Sentence denotes However, all reports only focus on BMI, an indirect marker of body fat.
T6 432-584 Sentence denotes Aim To explore the impact on COVID-19 severity of abdominal fat as a marker of body composition easily collected in patients undergoing a chest CT scan.
T7 585-593 Sentence denotes METHODS:
T8 594-811 Sentence denotes Patients included in this retrospective study were consecutively enrolled among those admitted to an Emergency Department in Rome, Italy, who tested positive for SARS-Cov-2 and underwent a chest CT scan in March 2020.
T9 812-864 Sentence denotes Data were extracted from electronic medical records.
T10 865-873 Sentence denotes RESULTS:
T11 874-938 Sentence denotes 150 patients were included (64.7% male, mean age 64 ± 16 years).
T12 939-1223 Sentence denotes Visceral fat (VAT) was significantly higher in patients requiring intensive care (p = .032), together with age (p = .009), inflammation markers CRP and LDH (p < .0001, p = .003, respectively), and interstitial pneumonia severity as assessed by a Lung Severity Score (LSS) (p < .0001).
T13 1224-1400 Sentence denotes Increasing age, lymphocytes, CRP, LDH, D-Dimer, LSS, total abdominal fat as well as VAT were found to have a significant univariate association with the need of intensive care.
T14 1401-1515 Sentence denotes A multivariate analysis showed that LSS and VAT were independently associated with the need of intensive care (OR:
T15 1516-1529 Sentence denotes 1.262; 95%CI:
T16 1530-1560 Sentence denotes 1.0171-1.488; p = .005 and OR:
T17 1561-1574 Sentence denotes 2.474; 95%CI:
T18 1575-1612 Sentence denotes 1.017-6.019; p = .046, respectively).
T19 1613-1695 Sentence denotes CONCLUSIONS: VAT is a marker of worse clinical outcomes in patients with COVID-19.
T20 1696-1852 Sentence denotes Given the exploratory nature of our study, further investigation is needed to confirm our findings and elucidate the mechanisms underlying such association.

Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-103 Sentence denotes Visceral fat shows the strongest association with the need of intensive Care in Patients with COVID-19.
T2 104-115 Sentence denotes BACKGROUND:
T3 116-227 Sentence denotes Obesity was recently identified as a major risk factor for worse COVID-19 severity, especially among the young.
T4 228-359 Sentence denotes The reason why its impact seems to be less pronounced in the elderly may be due to the concomitant presence of other comorbidities.
T5 360-431 Sentence denotes However, all reports only focus on BMI, an indirect marker of body fat.
T6 432-584 Sentence denotes Aim To explore the impact on COVID-19 severity of abdominal fat as a marker of body composition easily collected in patients undergoing a chest CT scan.
T7 585-593 Sentence denotes METHODS:
T8 594-811 Sentence denotes Patients included in this retrospective study were consecutively enrolled among those admitted to an Emergency Department in Rome, Italy, who tested positive for SARS-Cov-2 and underwent a chest CT scan in March 2020.
T9 812-864 Sentence denotes Data were extracted from electronic medical records.
T10 865-873 Sentence denotes RESULTS:
T11 874-938 Sentence denotes 150 patients were included (64.7% male, mean age 64 ± 16 years).
T12 939-1223 Sentence denotes Visceral fat (VAT) was significantly higher in patients requiring intensive care (p = .032), together with age (p = .009), inflammation markers CRP and LDH (p < .0001, p = .003, respectively), and interstitial pneumonia severity as assessed by a Lung Severity Score (LSS) (p < .0001).
T13 1224-1400 Sentence denotes Increasing age, lymphocytes, CRP, LDH, D-Dimer, LSS, total abdominal fat as well as VAT were found to have a significant univariate association with the need of intensive care.
T14 1401-1515 Sentence denotes A multivariate analysis showed that LSS and VAT were independently associated with the need of intensive care (OR:
T15 1516-1529 Sentence denotes 1.262; 95%CI:
T16 1530-1560 Sentence denotes 1.0171-1.488; p = .005 and OR:
T17 1561-1574 Sentence denotes 2.474; 95%CI:
T18 1575-1612 Sentence denotes 1.017-6.019; p = .046, respectively).
T19 1613-1695 Sentence denotes CONCLUSIONS: VAT is a marker of worse clinical outcomes in patients with COVID-19.
T20 1696-1852 Sentence denotes Given the exploratory nature of our study, further investigation is needed to confirm our findings and elucidate the mechanisms underlying such association.
T1 0-103 Sentence denotes Visceral fat shows the strongest association with the need of intensive Care in Patients with COVID-19.
T2 104-115 Sentence denotes BACKGROUND:
T3 116-227 Sentence denotes Obesity was recently identified as a major risk factor for worse COVID-19 severity, especially among the young.
T4 228-359 Sentence denotes The reason why its impact seems to be less pronounced in the elderly may be due to the concomitant presence of other comorbidities.
T5 360-431 Sentence denotes However, all reports only focus on BMI, an indirect marker of body fat.
T6 432-584 Sentence denotes Aim To explore the impact on COVID-19 severity of abdominal fat as a marker of body composition easily collected in patients undergoing a chest CT scan.
T7 585-593 Sentence denotes METHODS:
T8 594-811 Sentence denotes Patients included in this retrospective study were consecutively enrolled among those admitted to an Emergency Department in Rome, Italy, who tested positive for SARS-Cov-2 and underwent a chest CT scan in March 2020.
T9 812-864 Sentence denotes Data were extracted from electronic medical records.
T10 865-873 Sentence denotes RESULTS:
T11 874-938 Sentence denotes 150 patients were included (64.7% male, mean age 64 ± 16 years).
T12 939-1223 Sentence denotes Visceral fat (VAT) was significantly higher in patients requiring intensive care (p = .032), together with age (p = .009), inflammation markers CRP and LDH (p < .0001, p = .003, respectively), and interstitial pneumonia severity as assessed by a Lung Severity Score (LSS) (p < .0001).
T13 1224-1400 Sentence denotes Increasing age, lymphocytes, CRP, LDH, D-Dimer, LSS, total abdominal fat as well as VAT were found to have a significant univariate association with the need of intensive care.
T14 1401-1515 Sentence denotes A multivariate analysis showed that LSS and VAT were independently associated with the need of intensive care (OR:
T15 1516-1529 Sentence denotes 1.262; 95%CI:
T16 1530-1560 Sentence denotes 1.0171-1.488; p = .005 and OR:
T17 1561-1574 Sentence denotes 2.474; 95%CI:
T18 1575-1612 Sentence denotes 1.017-6.019; p = .046, respectively).
T19 1613-1695 Sentence denotes CONCLUSIONS: VAT is a marker of worse clinical outcomes in patients with COVID-19.
T20 1696-1852 Sentence denotes Given the exploratory nature of our study, further investigation is needed to confirm our findings and elucidate the mechanisms underlying such association.