PubMed:32691370 / 1952-2392 JSONTXT

{"project":"LitCovid-OGER-BB","denotations":[{"id":"T94","span":{"begin":20,"end":25},"obj":"SP_6"},{"id":"T95","span":{"begin":20,"end":25},"obj":"NCBITaxon:9606"},{"id":"T96","span":{"begin":41,"end":48},"obj":"GO:0010467"},{"id":"T97","span":{"begin":49,"end":53},"obj":"G_3"},{"id":"T98","span":{"begin":49,"end":53},"obj":"PG_10"},{"id":"T99","span":{"begin":49,"end":53},"obj":"PR:000003622"},{"id":"T100","span":{"begin":67,"end":76},"obj":"SP_7"},{"id":"T101","span":{"begin":100,"end":105},"obj":"NCBITaxon:10239"},{"id":"T102","span":{"begin":125,"end":129},"obj":"G_3"},{"id":"T103","span":{"begin":125,"end":129},"obj":"PG_10"},{"id":"T104","span":{"begin":125,"end":129},"obj":"PR:000003622"},{"id":"T105","span":{"begin":157,"end":162},"obj":"PR:000011271"},{"id":"T106","span":{"begin":190,"end":200},"obj":"GO:0008219"},{"id":"T107","span":{"begin":204,"end":214},"obj":"GO:0070269"},{"id":"T108","span":{"begin":217,"end":226},"obj":"SP_7"},{"id":"T109","span":{"begin":270,"end":280},"obj":"GO:0019835"},{"id":"T110","span":{"begin":319,"end":326},"obj":"GO:0010467"},{"id":"T111","span":{"begin":332,"end":335},"obj":"CHEBI:37886"},{"id":"T112","span":{"begin":332,"end":335},"obj":"CHEBI:37886"},{"id":"T113","span":{"begin":332,"end":338},"obj":"PR:000036009"},{"id":"T114","span":{"begin":371,"end":376},"obj":"PR:000011271"},{"id":"T115","span":{"begin":405,"end":408},"obj":"CHEBI:37886"},{"id":"T116","span":{"begin":405,"end":408},"obj":"CHEBI:37886"},{"id":"T117","span":{"begin":405,"end":411},"obj":"PR:000036009"},{"id":"T118","span":{"begin":429,"end":439},"obj":"GO:0070269"}],"namespaces":[{"prefix":"NCBITaxon","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"}],"text":"Graphical Abstract •Human VSELs and HSCs express ACE2 receptor for SARS-CoV2 entry. •Interaction of viral spike protein with ACE2 receptor may hyperactivate Nlrp3 inflammasome which induces cell death by pyroptosis. •SARS-CoV2 may also enter cells and eliminate them by cell lysis. •What is not shown since these cells express also Ang II receptor they may hyperactivate Nlrp3 inflammasome in response to Ang II which may induce pyroptosis."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T26","span":{"begin":112,"end":119},"obj":"Body_part"},{"id":"T27","span":{"begin":190,"end":194},"obj":"Body_part"},{"id":"T28","span":{"begin":242,"end":247},"obj":"Body_part"},{"id":"T29","span":{"begin":270,"end":274},"obj":"Body_part"},{"id":"T30","span":{"begin":313,"end":318},"obj":"Body_part"}],"attributes":[{"id":"A26","pred":"fma_id","subj":"T26","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A27","pred":"fma_id","subj":"T27","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A28","pred":"fma_id","subj":"T28","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A29","pred":"fma_id","subj":"T29","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A30","pred":"fma_id","subj":"T30","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":"Graphical Abstract •Human VSELs and HSCs express ACE2 receptor for SARS-CoV2 entry. •Interaction of viral spike protein with ACE2 receptor may hyperactivate Nlrp3 inflammasome which induces cell death by pyroptosis. •SARS-CoV2 may also enter cells and eliminate them by cell lysis. •What is not shown since these cells express also Ang II receptor they may hyperactivate Nlrp3 inflammasome in response to Ang II which may induce pyroptosis."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T6","span":{"begin":67,"end":71},"obj":"Disease"},{"id":"T7","span":{"begin":217,"end":221},"obj":"Disease"}],"attributes":[{"id":"A6","pred":"mondo_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A7","pred":"mondo_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"Graphical Abstract •Human VSELs and HSCs express ACE2 receptor for SARS-CoV2 entry. •Interaction of viral spike protein with ACE2 receptor may hyperactivate Nlrp3 inflammasome which induces cell death by pyroptosis. •SARS-CoV2 may also enter cells and eliminate them by cell lysis. •What is not shown since these cells express also Ang II receptor they may hyperactivate Nlrp3 inflammasome in response to Ang II which may induce pyroptosis."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T36","span":{"begin":20,"end":25},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T37","span":{"begin":190,"end":194},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T38","span":{"begin":242,"end":247},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T39","span":{"begin":270,"end":274},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T40","span":{"begin":313,"end":318},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"text":"Graphical Abstract •Human VSELs and HSCs express ACE2 receptor for SARS-CoV2 entry. •Interaction of viral spike protein with ACE2 receptor may hyperactivate Nlrp3 inflammasome which induces cell death by pyroptosis. •SARS-CoV2 may also enter cells and eliminate them by cell lysis. •What is not shown since these cells express also Ang II receptor they may hyperactivate Nlrp3 inflammasome in response to Ang II which may induce pyroptosis."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T15","span":{"begin":112,"end":119},"obj":"Chemical"},{"id":"T16","span":{"begin":336,"end":338},"obj":"Chemical"},{"id":"T17","span":{"begin":409,"end":411},"obj":"Chemical"}],"attributes":[{"id":"A15","pred":"chebi_id","subj":"T15","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A16","pred":"chebi_id","subj":"T16","obj":"http://purl.obolibrary.org/obo/CHEBI_74067"},{"id":"A17","pred":"chebi_id","subj":"T17","obj":"http://purl.obolibrary.org/obo/CHEBI_74067"}],"text":"Graphical Abstract •Human VSELs and HSCs express ACE2 receptor for SARS-CoV2 entry. •Interaction of viral spike protein with ACE2 receptor may hyperactivate Nlrp3 inflammasome which induces cell death by pyroptosis. •SARS-CoV2 may also enter cells and eliminate them by cell lysis. •What is not shown since these cells express also Ang II receptor they may hyperactivate Nlrp3 inflammasome in response to Ang II which may induce pyroptosis."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T5","span":{"begin":190,"end":200},"obj":"http://purl.obolibrary.org/obo/GO_0008219"},{"id":"T6","span":{"begin":204,"end":214},"obj":"http://purl.obolibrary.org/obo/GO_0070269"},{"id":"T7","span":{"begin":275,"end":280},"obj":"http://purl.obolibrary.org/obo/GO_0019835"},{"id":"T8","span":{"begin":429,"end":439},"obj":"http://purl.obolibrary.org/obo/GO_0070269"}],"text":"Graphical Abstract •Human VSELs and HSCs express ACE2 receptor for SARS-CoV2 entry. •Interaction of viral spike protein with ACE2 receptor may hyperactivate Nlrp3 inflammasome which induces cell death by pyroptosis. •SARS-CoV2 may also enter cells and eliminate them by cell lysis. •What is not shown since these cells express also Ang II receptor they may hyperactivate Nlrp3 inflammasome in response to Ang II which may induce pyroptosis."}

{"project":"LitCovid-sentences","denotations":[{"id":"T11","span":{"begin":0,"end":440},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Graphical Abstract •Human VSELs and HSCs express ACE2 receptor for SARS-CoV2 entry. •Interaction of viral spike protein with ACE2 receptor may hyperactivate Nlrp3 inflammasome which induces cell death by pyroptosis. •SARS-CoV2 may also enter cells and eliminate them by cell lysis. •What is not shown since these cells express also Ang II receptor they may hyperactivate Nlrp3 inflammasome in response to Ang II which may induce pyroptosis."}