PubMed:32657586
Annnotations
Inflammaging
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-99 | Sentence | denotes | Proteomics and Informatics for Understanding Phases and Identifying Biomarkers in COVID-19 Disease. |
| T2 | 100-283 | Sentence | denotes | The emergence of novel coronavirus disease 2019 (COVID-19), caused by the SARS-CoV-2 coronavirus, has necessitated the urgent development of new diagnostic and therapeutic strategies. |
| T3 | 284-426 | Sentence | denotes | Rapid research and development, on an international scale, has already generated assays for detecting SARS-CoV-2 RNA and host immunoglobulins. |
| T4 | 427-581 | Sentence | denotes | However, the complexities of COVID-19 are such that fuller definitions of patient status, trajectory, sequelae, and responses to therapy are now required. |
| T5 | 582-734 | Sentence | denotes | There is accumulating evidence-from studies of both COVID-19 and the related disease SARS-that protein biomarkers could help to provide this definition. |
| T6 | 735-969 | Sentence | denotes | Proteins associated with blood coagulation (D-dimer), cell damage (lactate dehydrogenase), and the inflammatory response (e.g., C-reactive protein) have already been identified as possible predictors of COVID-19 severity or mortality. |
| T7 | 970-1094 | Sentence | denotes | Proteomics technologies, with their ability to detect many proteins per analysis, have begun to extend these early findings. |
| T8 | 1095-1327 | Sentence | denotes | To be effective, proteomics strategies must include not only methods for comprehensive data acquisition (e.g., using mass spectrometry) but also informatics approaches via which to derive actionable information from large data sets. |
| T9 | 1328-1521 | Sentence | denotes | Here we review applications of proteomics to COVID-19 and SARS and outline how pipelines involving technologies such as artificial intelligence could be of value for research on these diseases. |
| T1 | 0-99 | Sentence | denotes | Proteomics and Informatics for Understanding Phases and Identifying Biomarkers in COVID-19 Disease. |
| T2 | 100-283 | Sentence | denotes | The emergence of novel coronavirus disease 2019 (COVID-19), caused by the SARS-CoV-2 coronavirus, has necessitated the urgent development of new diagnostic and therapeutic strategies. |
| T3 | 284-426 | Sentence | denotes | Rapid research and development, on an international scale, has already generated assays for detecting SARS-CoV-2 RNA and host immunoglobulins. |
| T4 | 427-581 | Sentence | denotes | However, the complexities of COVID-19 are such that fuller definitions of patient status, trajectory, sequelae, and responses to therapy are now required. |
| T5 | 582-734 | Sentence | denotes | There is accumulating evidence-from studies of both COVID-19 and the related disease SARS-that protein biomarkers could help to provide this definition. |
| T6 | 735-969 | Sentence | denotes | Proteins associated with blood coagulation (D-dimer), cell damage (lactate dehydrogenase), and the inflammatory response (e.g., C-reactive protein) have already been identified as possible predictors of COVID-19 severity or mortality. |
| T7 | 970-1094 | Sentence | denotes | Proteomics technologies, with their ability to detect many proteins per analysis, have begun to extend these early findings. |
| T8 | 1095-1327 | Sentence | denotes | To be effective, proteomics strategies must include not only methods for comprehensive data acquisition (e.g., using mass spectrometry) but also informatics approaches via which to derive actionable information from large data sets. |
| T9 | 1328-1521 | Sentence | denotes | Here we review applications of proteomics to COVID-19 and SARS and outline how pipelines involving technologies such as artificial intelligence could be of value for research on these diseases. |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T1 | 397-400 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T2 | 410-425 | Body_part | denotes | immunoglobulins | http://purl.org/sig/ont/fma/fma62871 |
| T3 | 677-684 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T4 | 735-743 | Body_part | denotes | Proteins | http://purl.org/sig/ont/fma/fma67257 |
| T5 | 760-765 | Body_part | denotes | blood | http://purl.org/sig/ont/fma/fma9670 |
| T6 | 789-793 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T7 | 874-881 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T8 | 1029-1037 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 336-341 | Body_part | denotes | scale | http://purl.obolibrary.org/obo/UBERON_0002542 |
| T2 | 760-765 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 82-90 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T2 | 123-147 | Disease | denotes | coronavirus disease 2019 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T3 | 149-157 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T4 | 174-182 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T5 | 386-394 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T6 | 456-464 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T7 | 634-642 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T8 | 667-671 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T9 | 938-946 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T10 | 1373-1381 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T11 | 1386-1390 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 198-201 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T2 | 343-346 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T3 | 760-765 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
| T4 | 760-765 | http://www.ebi.ac.uk/efo/EFO_0000296 | denotes | blood |
| T5 | 789-793 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T1 | 677-684 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T2 | 802-809 | Chemical | denotes | lactate | http://purl.obolibrary.org/obo/CHEBI_24996 |
| T3 | 874-881 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T4 | 1029-1037 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 760-777 | http://purl.obolibrary.org/obo/GO_0007596 | denotes | blood coagulation |
| T2 | 766-777 | http://purl.obolibrary.org/obo/GO_0050817 | denotes | coagulation |
| T3 | 834-855 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammatory response |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-99 | Sentence | denotes | Proteomics and Informatics for Understanding Phases and Identifying Biomarkers in COVID-19 Disease. |
| T2 | 100-283 | Sentence | denotes | The emergence of novel coronavirus disease 2019 (COVID-19), caused by the SARS-CoV-2 coronavirus, has necessitated the urgent development of new diagnostic and therapeutic strategies. |
| T3 | 284-426 | Sentence | denotes | Rapid research and development, on an international scale, has already generated assays for detecting SARS-CoV-2 RNA and host immunoglobulins. |
| T4 | 427-581 | Sentence | denotes | However, the complexities of COVID-19 are such that fuller definitions of patient status, trajectory, sequelae, and responses to therapy are now required. |
| T5 | 582-734 | Sentence | denotes | There is accumulating evidence-from studies of both COVID-19 and the related disease SARS-that protein biomarkers could help to provide this definition. |
| T6 | 735-969 | Sentence | denotes | Proteins associated with blood coagulation (D-dimer), cell damage (lactate dehydrogenase), and the inflammatory response (e.g., C-reactive protein) have already been identified as possible predictors of COVID-19 severity or mortality. |
| T7 | 970-1094 | Sentence | denotes | Proteomics technologies, with their ability to detect many proteins per analysis, have begun to extend these early findings. |
| T8 | 1095-1327 | Sentence | denotes | To be effective, proteomics strategies must include not only methods for comprehensive data acquisition (e.g., using mass spectrometry) but also informatics approaches via which to derive actionable information from large data sets. |
| T9 | 1328-1521 | Sentence | denotes | Here we review applications of proteomics to COVID-19 and SARS and outline how pipelines involving technologies such as artificial intelligence could be of value for research on these diseases. |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 1 | 82-90 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 17 | 117-142 | Disease | denotes | novel coronavirus disease | MESH:C000657245 |
| 18 | 149-157 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 19 | 174-184 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 20 | 185-196 | Species | denotes | coronavirus | Tax:11118 |
| 21 | 386-396 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 22 | 456-464 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 23 | 501-508 | Species | denotes | patient | Tax:9606 |
| 24 | 634-642 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 25 | 667-671 | Disease | denotes | SARS | MESH:D045169 |
| 26 | 760-777 | Disease | denotes | blood coagulation | MESH:D001778 |
| 27 | 863-881 | Gene | denotes | C-reactive protein | Gene:1401 |
| 28 | 938-946 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 29 | 959-968 | Disease | denotes | mortality | MESH:D003643 |
| 30 | 1373-1381 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 31 | 1386-1390 | Disease | denotes | SARS | MESH:D045169 |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-99 | Sentence | denotes | Proteomics and Informatics for Understanding Phases and Identifying Biomarkers in COVID-19 Disease. |
| T2 | 100-283 | Sentence | denotes | The emergence of novel coronavirus disease 2019 (COVID-19), caused by the SARS-CoV-2 coronavirus, has necessitated the urgent development of new diagnostic and therapeutic strategies. |
| T3 | 284-426 | Sentence | denotes | Rapid research and development, on an international scale, has already generated assays for detecting SARS-CoV-2 RNA and host immunoglobulins. |
| T4 | 427-581 | Sentence | denotes | However, the complexities of COVID-19 are such that fuller definitions of patient status, trajectory, sequelae, and responses to therapy are now required. |
| T5 | 582-734 | Sentence | denotes | There is accumulating evidence-from studies of both COVID-19 and the related disease SARS-that protein biomarkers could help to provide this definition. |
| T6 | 735-969 | Sentence | denotes | Proteins associated with blood coagulation (D-dimer), cell damage (lactate dehydrogenase), and the inflammatory response (e.g., C-reactive protein) have already been identified as possible predictors of COVID-19 severity or mortality. |
| T7 | 970-1094 | Sentence | denotes | Proteomics technologies, with their ability to detect many proteins per analysis, have begun to extend these early findings. |
| T8 | 1095-1327 | Sentence | denotes | To be effective, proteomics strategies must include not only methods for comprehensive data acquisition (e.g., using mass spectrometry) but also informatics approaches via which to derive actionable information from large data sets. |
| T9 | 1328-1521 | Sentence | denotes | Here we review applications of proteomics to COVID-19 and SARS and outline how pipelines involving technologies such as artificial intelligence could be of value for research on these diseases. |
| T1 | 0-99 | Sentence | denotes | Proteomics and Informatics for Understanding Phases and Identifying Biomarkers in COVID-19 Disease. |
| T2 | 100-283 | Sentence | denotes | The emergence of novel coronavirus disease 2019 (COVID-19), caused by the SARS-CoV-2 coronavirus, has necessitated the urgent development of new diagnostic and therapeutic strategies. |
| T3 | 284-426 | Sentence | denotes | Rapid research and development, on an international scale, has already generated assays for detecting SARS-CoV-2 RNA and host immunoglobulins. |
| T4 | 427-581 | Sentence | denotes | However, the complexities of COVID-19 are such that fuller definitions of patient status, trajectory, sequelae, and responses to therapy are now required. |
| T5 | 582-734 | Sentence | denotes | There is accumulating evidence-from studies of both COVID-19 and the related disease SARS-that protein biomarkers could help to provide this definition. |
| T6 | 735-969 | Sentence | denotes | Proteins associated with blood coagulation (D-dimer), cell damage (lactate dehydrogenase), and the inflammatory response (e.g., C-reactive protein) have already been identified as possible predictors of COVID-19 severity or mortality. |
| T7 | 970-1094 | Sentence | denotes | Proteomics technologies, with their ability to detect many proteins per analysis, have begun to extend these early findings. |
| T8 | 1095-1327 | Sentence | denotes | To be effective, proteomics strategies must include not only methods for comprehensive data acquisition (e.g., using mass spectrometry) but also informatics approaches via which to derive actionable information from large data sets. |
| T9 | 1328-1521 | Sentence | denotes | Here we review applications of proteomics to COVID-19 and SARS and outline how pipelines involving technologies such as artificial intelligence could be of value for research on these diseases. |
Glycosmos6-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 760-765 | http://purl.obolibrary.org/obo/MAT_0000083 | denotes | blood |
| T2 | 760-765 | http://purl.obolibrary.org/obo/MAT_0000315 | denotes | blood |
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 82-90 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T2 | 123-147 | Disease | denotes | coronavirus disease 2019 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T3 | 149-157 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T4 | 174-184 | Disease | denotes | SARS-CoV-2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T5 | 386-396 | Disease | denotes | SARS-CoV-2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T6 | 456-464 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T7 | 634-642 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T8 | 667-671 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T9 | 938-946 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T10 | 1373-1381 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T11 | 1386-1390 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 760-765 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 123-147 | OrganismTaxon | denotes | coronavirus disease 2019 | 2697049 |
| T2 | 174-182 | OrganismTaxon | denotes | SARS-CoV | 694009 |
| T3 | 386-394 | OrganismTaxon | denotes | SARS-CoV | 694009 |
| T4 | 501-508 | OrganismTaxon | denotes | patient | 9606 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 336-341 | Body_part | denotes | scale | http://purl.obolibrary.org/obo/UBERON_0002542 |
| T2 | 760-765 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |