PubMed:32654489
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T1 | 810-818 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T2 | 1234-1239 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 875-881 | Body_part | denotes | corpus | http://purl.obolibrary.org/obo/UBERON_3000645 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 49-57 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T2 | 172-196 | Disease | denotes | coronavirus disease 2019 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T3 | 198-206 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T4 | 238-271 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T5 | 285-293 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T6 | 401-409 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T7 | 516-524 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T8 | 636-644 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T9 | 1143-1151 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T10 | 1208-1216 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T11 | 1514-1522 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 166-171 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T2 | 354-355 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T3 | 435-436 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T4 | 686-687 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T5 | 819-824 | http://purl.obolibrary.org/obo/OGG_0000000002 | denotes | genes |
| T6 | 856-857 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T7 | 960-961 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T8 | 1016-1018 | http://purl.obolibrary.org/obo/CLO_0053794 | denotes | 41 |
| T9 | 1228-1239 | http://purl.obolibrary.org/obo/CLO_0053065 | denotes | human cells |
| T10 | 1353-1354 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T1 | 626-631 | Chemical | denotes | drugs | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T2 | 793-798 | Chemical | denotes | drugs | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T3 | 810-818 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T4 | 1032-1037 | Chemical | denotes | drugs | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T5 | 1049-1062 | Chemical | denotes | dexamethasone | http://purl.obolibrary.org/obo/CHEBI_41879 |
| T6 | 1095-1105 | Chemical | denotes | toremifene | http://purl.obolibrary.org/obo/CHEBI_9635 |
| T7 | 1330-1335 | Chemical | denotes | drugs | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T8 | 1413-1418 | Chemical | denotes | drugs | http://purl.obolibrary.org/obo/CHEBI_23888 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 69-77 | http://purl.obolibrary.org/obo/GO_0007612 | denotes | Learning |
| T2 | 580-588 | http://purl.obolibrary.org/obo/GO_0007612 | denotes | learning |
| T3 | 982-990 | http://purl.obolibrary.org/obo/GO_0007612 | denotes | learning |
| T4 | 1369-1377 | http://purl.obolibrary.org/obo/GO_0007612 | denotes | learning |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 1 | 49-57 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 19 | 150-156 | Disease | denotes | deaths | MESH:D003643 |
| 20 | 172-196 | Disease | denotes | coronavirus disease 2019 | MESH:C000657245 |
| 21 | 198-206 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 22 | 238-283 | Species | denotes | severe acute respiratory syndrome coronavirus | Tax:694009 |
| 23 | 285-295 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 24 | 401-409 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 25 | 516-524 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 26 | 636-644 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 27 | 653-656 | Species | denotes | CoV | Tax:11118 |
| 28 | 1049-1062 | Chemical | denotes | dexamethasone | MESH:D003907 |
| 29 | 1064-1076 | Chemical | denotes | indomethacin | MESH:D007213 |
| 30 | 1078-1089 | Chemical | denotes | niclosamide | MESH:D009534 |
| 31 | 1095-1105 | Chemical | denotes | toremifene | MESH:D017312 |
| 32 | 1143-1151 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 33 | 1208-1227 | Disease | denotes | SARS-CoV-2-infected | MESH:C000657245 |
| 34 | 1228-1233 | Species | denotes | human | Tax:9606 |
| 35 | 1514-1522 | Disease | denotes | COVID-19 | MESH:C000657245 |
LitCovid_AGAC_only
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| p53299s29 | 216-220 | Reg | denotes | , ca |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-78 | Sentence | denotes | Repurpose Open Data to Discover Therapeutics for COVID-19 Using Deep Learning. |
| T2 | 79-325 | Sentence | denotes | There have been more than 2.2 million confirmed cases and over 120 000 deaths from the human coronavirus disease 2019 (COVID-19) pandemic, caused by the novel severe acute respiratory syndrome coronavirus (SARS-CoV-2), in the United States alone. |
| T3 | 326-410 | Sentence | denotes | However, there is currently a lack of proven effective medications against COVID-19. |
| T4 | 411-525 | Sentence | denotes | Drug repurposing offers a promising route for the development of prevention and treatment strategies for COVID-19. |
| T5 | 526-662 | Sentence | denotes | This study reports an integrative, network-based deep-learning methodology to identify repurposable drugs for COVID-19 (termed CoV-KGE). |
| T6 | 663-916 | Sentence | denotes | Specifically, we built a comprehensive knowledge graph that includes 15 million edges across 39 types of relationships connecting drugs, diseases, proteins/genes, pathways, and expression from a large scientific corpus of 24 million PubMed publications. |
| T7 | 917-1278 | Sentence | denotes | Using Amazon's AWS computing resources and a network-based, deep-learning framework, we identified 41 repurposable drugs (including dexamethasone, indomethacin, niclosamide, and toremifene) whose therapeutic associations with COVID-19 were validated by transcriptomic and proteomics data in SARS-CoV-2-infected human cells and data from ongoing clinical trials. |
| T8 | 1279-1523 | Sentence | denotes | Whereas this study by no means recommends specific drugs, it demonstrates a powerful deep-learning methodology to prioritize existing drugs for further investigation, which holds the potential to accelerate therapeutic development for COVID-19. |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-78 | Sentence | denotes | Repurpose Open Data to Discover Therapeutics for COVID-19 Using Deep Learning. |
| T2 | 79-325 | Sentence | denotes | There have been more than 2.2 million confirmed cases and over 120 000 deaths from the human coronavirus disease 2019 (COVID-19) pandemic, caused by the novel severe acute respiratory syndrome coronavirus (SARS-CoV-2), in the United States alone. |
| T3 | 326-410 | Sentence | denotes | However, there is currently a lack of proven effective medications against COVID-19. |
| T4 | 411-525 | Sentence | denotes | Drug repurposing offers a promising route for the development of prevention and treatment strategies for COVID-19. |
| T5 | 526-662 | Sentence | denotes | This study reports an integrative, network-based deep-learning methodology to identify repurposable drugs for COVID-19 (termed CoV-KGE). |
| T6 | 663-916 | Sentence | denotes | Specifically, we built a comprehensive knowledge graph that includes 15 million edges across 39 types of relationships connecting drugs, diseases, proteins/genes, pathways, and expression from a large scientific corpus of 24 million PubMed publications. |
| T7 | 917-1278 | Sentence | denotes | Using Amazon's AWS computing resources and a network-based, deep-learning framework, we identified 41 repurposable drugs (including dexamethasone, indomethacin, niclosamide, and toremifene) whose therapeutic associations with COVID-19 were validated by transcriptomic and proteomics data in SARS-CoV-2-infected human cells and data from ongoing clinical trials. |
| T8 | 1279-1523 | Sentence | denotes | Whereas this study by no means recommends specific drugs, it demonstrates a powerful deep-learning methodology to prioritize existing drugs for further investigation, which holds the potential to accelerate therapeutic development for COVID-19. |
| T1 | 0-78 | Sentence | denotes | Repurpose Open Data to Discover Therapeutics for COVID-19 Using Deep Learning. |
| T2 | 79-325 | Sentence | denotes | There have been more than 2.2 million confirmed cases and over 120 000 deaths from the human coronavirus disease 2019 (COVID-19) pandemic, caused by the novel severe acute respiratory syndrome coronavirus (SARS-CoV-2), in the United States alone. |
| T3 | 326-410 | Sentence | denotes | However, there is currently a lack of proven effective medications against COVID-19. |
| T4 | 411-525 | Sentence | denotes | Drug repurposing offers a promising route for the development of prevention and treatment strategies for COVID-19. |
| T5 | 526-662 | Sentence | denotes | This study reports an integrative, network-based deep-learning methodology to identify repurposable drugs for COVID-19 (termed CoV-KGE). |
| T6 | 663-916 | Sentence | denotes | Specifically, we built a comprehensive knowledge graph that includes 15 million edges across 39 types of relationships connecting drugs, diseases, proteins/genes, pathways, and expression from a large scientific corpus of 24 million PubMed publications. |
| T7 | 917-1278 | Sentence | denotes | Using Amazon's AWS computing resources and a network-based, deep-learning framework, we identified 41 repurposable drugs (including dexamethasone, indomethacin, niclosamide, and toremifene) whose therapeutic associations with COVID-19 were validated by transcriptomic and proteomics data in SARS-CoV-2-infected human cells and data from ongoing clinical trials. |
| T8 | 1279-1523 | Sentence | denotes | Whereas this study by no means recommends specific drugs, it demonstrates a powerful deep-learning methodology to prioritize existing drugs for further investigation, which holds the potential to accelerate therapeutic development for COVID-19. |
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 49-57 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T2 | 172-196 | Disease | denotes | coronavirus disease 2019 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T3 | 198-206 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T4 | 238-271 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T5 | 285-295 | Disease | denotes | SARS-CoV-2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T6 | 401-409 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T7 | 516-524 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T8 | 636-644 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T9 | 1143-1151 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T10 | 1208-1218 | Disease | denotes | SARS-CoV-2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T11 | 1514-1522 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 166-171 | OrganismTaxon | denotes | human | 9606 |
| T2 | 172-196 | OrganismTaxon | denotes | coronavirus disease 2019 | 2697049 |
| T3 | 238-271 | OrganismTaxon | denotes | severe acute respiratory syndrome | 694009 |
| T4 | 285-293 | OrganismTaxon | denotes | SARS-CoV | 694009 |
| T5 | 1208-1216 | OrganismTaxon | denotes | SARS-CoV | 694009 |
| T6 | 1228-1233 | OrganismTaxon | denotes | human | 9606 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 875-881 | Body_part | denotes | corpus | http://purl.obolibrary.org/obo/UBERON_0004360|http://purl.obolibrary.org/obo/UBERON_3000645 |